iiinova — where your digital self keeps evolving

Reposted by Sara Nowinski

Van Andel Institute (VAI) @vai.org · 15/09/2026

Congratulations to Drs. James Eapen, Abigail Godec, Lauren Harmon and Riley Wedan, who recently earned their Ph.D.s in molecular and cellular biology from Van Andel Institute Graduate School. We look forward to seeing where their passion for discovery takes them next!

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Reposted by Sara Nowinski

Sara Nowinski @saranowinski.bsky.social · 26/05/2026

Big weekend for the Nowinski lab! TWO new mtFAS preprints online!

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Reposted by Sara Nowinski

bioRxivpreprint @biorxivpreprint.bsky.social · 23/05/2026

Cells Engage Endogenous Malonate Synthesis to Drive Mitochondrial Metabolism www.biorxiv.org/content/10.64898/20…

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Reposted by Sara Nowinski

bioRxivpreprint @biorxivpreprint.bsky.social · 23/05/2026

Functional partitioning of lipoic acid decouples cellular abundance from mitochondrial utilization www.biorxiv.org/content/10.64898/20…

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Sara Nowinski @saranowinski.bsky.social · 26/05/2026

Big weekend for the Nowinski lab! TWO new mtFAS preprints online!

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Reposted by Sara Nowinski

Sara Nowinski @saranowinski.bsky.social · 04/03/2026

Hot meeting alert!! 🚨🚨 @vai.org is hosting Rising Stars and Horizons in Metabolism, a new format, 2 day symposium highlighting both established and up and coming leaders in Metabolic research. Check it out and register here: www.vai.org/event/rising...

vai.org

Rising Stars in Metabolism Symposium

Join us for Rising Stars in Metabolism Symposium at Van Andel Institute Stay informed about exciting upcoming events and activities.

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Sara Nowinski @saranowinski.bsky.social · 04/03/2026

vai.org

Rising Stars in Metabolism Symposium

Join us for Rising Stars in Metabolism Symposium at Van Andel Institute Stay informed about exciting upcoming events and activities.

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Sara Nowinski @saranowinski.bsky.social · 10/10/2025

Whoo hoo! The final version of our first paper is online! So proud of the team. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

kwnsfk27.r.eu-west-1.awstrack.me

Redirecting

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Reposted by Sara Nowinski

Katsu Funai @katsufunai.bsky.social · 28/08/2025

We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the University of Utah their new home to build a metabolic research program. Please share! @uofunuip.bsky.social

nature.com

Open Rank, Tenure Track Position – Metabolic Physiology - Salt Lake City, Utah job with University of Utah, Department of Nutrition & Integrative Physiology | 12844064

The Department of Nutrition and Integrated Physiology (NUIP) at the University of Utah seeks a Tenure Track faculty member at the rank of Assistant...

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Reposted by Sara Nowinski

Sara Nowinski @saranowinski.bsky.social · 18/08/2025

Abstracts for Midwest Metabolism / TriMAD meeting are due Sept 8! That’s 2 weeks away folks! Join us in Ann Arbor this fall. www.vai.org/event/2025-m...

vai.org

2025 Midwest Metabolism Meeting

Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.

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Sara Nowinski @saranowinski.bsky.social · 18/08/2025

Abstracts for Midwest Metabolism / TriMAD meeting are due Sept 8! That’s 2 weeks away folks! Join us in Ann Arbor this fall. www.vai.org/event/2025-m...

vai.org

2025 Midwest Metabolism Meeting

Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.

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Reposted by Sara Nowinski

Nick Burton @nickburton.bsky.social · 12/08/2025

I’m really beyond thrilled to be included in this years Pew Biomedical Scholars cohort and to be able to meet all the incredible scientists in this program. I was in Scott Kennedy’s lab when he was a Pew Scholar and never thought I’d be lucky enough to also be one! www.pew.org/en/about/new...

pew.org

Pew Awards 22 Researchers Biomedical Science Grants

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Reposted by Sara Nowinski

Judi Simcox @judisimcox.bsky.social · 10/07/2025

Officially tenured. Thank you to all the mentors who guided me, and to the trainees who made this possible with your ideas, hard work, and scientific joy.

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Reposted by Sara Nowinski

Mark Peifer (He, him) @peiferlabunc.bsky.social · 02/07/2025

For ESIs dealing with grants being rescinded: if an investigator’s 1st substantial independent research award is terminated within the first 3 years of the project period (not due to scientific misconduct ) they can request the reinstatement of ESI status grants.nih.gov/news-events/...

My First Substantial Independent Research Award Was Terminated Early. Can My ESI Status Be Reinstated?
June 12, 2025
Investigators lose their Early Stage Investigator (ESI) eligibility when they successfully compete for and receive a substantial independent research award. In the event an investigator’s first substantial independent research award is terminated within the first three years of the project period, and this was not due to scientific misconduct or other disqualifying events, the investigator can request the reinstatement of ESI status, using the ESI Extensions request tool in eRA commons. See Requesting an Extension for instructions.

For more, see the Early Stage Investigators FAQ page.

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Sara Nowinski @saranowinski.bsky.social · 11/06/2025

Amazing NoWINski lab showing at the VAI scientific retreat - 3 poster session awards to 3 very talented lab trainees! #proudPI

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Reposted by Sara Nowinski

Sara Nowinski @saranowinski.bsky.social · 04/06/2025

Sign up for midwest metabolism & Trimad joint meeting! Abstracts are due 9/2/25. The vast majority of talks will come from the abstracts - great opportunity for trainees! www.vai.org/event/2025-m...

vai.org

2025 Midwest Metabolism Meeting

Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.

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Sara Nowinski @saranowinski.bsky.social · 04/06/2025

Sign up for midwest metabolism & Trimad joint meeting! Abstracts are due 9/2/25. The vast majority of talks will come from the abstracts - great opportunity for trainees! www.vai.org/event/2025-m...

vai.org

2025 Midwest Metabolism Meeting

Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.

01815

Reposted by Sara Nowinski

Brandon Chen, PhD @brandontwchen.bsky.social · 17/04/2025

Happy to share our most recent review on mitochondria-organelle metabolic communication with Yatrik Shah and Costas Lyssiotis now online at Molecular Cell! We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals! www.sciencedirect.com/science/arti...

sciencedirect.com

Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis

Mitochondria serve as central hubs in cellular metabolism by sensing, integrating, and responding to metabolic demands. This integrative function is a…

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Reposted by Sara Nowinski

Eddie Rashan @edreesrashan.bsky.social · 12/04/2025

I'm excited to present my work on the deorphanization of atypical lipid catabolic enzymes at #ASBMB25 on Monday April 14th. Please come to W179 to hear my flash-talk at 9:30AM and hang out with me at poster #350! #lipidtime

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Reposted by Sara Nowinski

Sara Nowinski @saranowinski.bsky.social · 29/03/2025

Registration is live for the 1st ever Midwest Metabolism & TRiMAD dual meeting, hosted jointly by VAI + U of M in Ann Arbor, MI November 10-11, 2025! We have some exciting speakers but most will come from abstracts so submit your best #mitochondria & #metabolism research! www.vai.org/event/2025-m...

vai.org

2025 Midwest Metabolism Meeting

Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.

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Sara Nowinski @saranowinski.bsky.social · 29/03/2025

vai.org

2025 Midwest Metabolism Meeting

Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.

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Reposted by Sara Nowinski

Nick Burton @nickburton.bsky.social · 28/02/2025

I’m going to staple these peeves to my door just so my students know it’s not just me.

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Sara Nowinski @saranowinski.bsky.social · 26/02/2025

I’ve had such a great few days of science and sunshine thanks to @fusionconf.bsky.social !! Super big congrats to lab postdoc Sam Preston who won a poster award!! Many thanks to the organizers for an awesome meeting.

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Reposted by Sara Nowinski

Lucas Sullivan @lucasbsullivan.bsky.social · 20/02/2025

Next, our 2nd preprint of the week (!), this one driven by @madelouhart.bsky.social Previously: Mitochondrial inhibition impairs cell proliferation by constraining aspartate (ASP) availability. Here: we investigate the kinetics of ASP depletion/ proliferation impairments and...surprises ensue!

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Reposted by Sara Nowinski

Lucas Sullivan @lucasbsullivan.bsky.social · 20/02/2025

Excited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside: A broadly applicable serum-free media, Quantitative lipid uptake characterization, Evidence lipid scavenging > synthesis for cancer cell proliferation.

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Reposted by Sara Nowinski

Jason Cantor @jasonrcantor.bsky.social · 10/02/2025

excited to share a new preprint from our lab! led by the outstanding (& newly minted PhD) @thebiokimist.bsky.social we first uncover a basis for conditional HK2 essentiality in HPLM - leveraging this dependence then leads us to distinct rationale underlying why the Warburg Effect is beneficial!

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Reposted by Sara Nowinski

Scott Soleimanpour @soleimanpourlab.bsky.social · 06/02/2025

A post over a decade in the making… 🙌beyond excited to share our work out today in @science.org. We found that retrograde (mitonuclear) signaling regulates the identity and maturity of metabolic tissues.🧵 1/6 www.science.org/doi/10.1126/...

science.org

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

Mitochondrial damage is a hallmark of metabolic diseases, including diabetes, yet the consequences of compromised mitochondria in metabolic tissues are often unclear. Here, we report that dysfunctiona...

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Sara Nowinski @saranowinski.bsky.social · 02/02/2025

Finally made the effort to go back to that other app that used to be the bird app and actually delete my account… feels good!

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Reposted by Sara Nowinski

Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 30/01/2025

This account is for sharing info with US scientists, both extramural and intramural to NIH, about attacks on science in the US. Education is power, and we can help advocate for science and medicine together. 💪🧪 We are a team of NIH people. Please ask us questions you might have.

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Reposted by Sara Nowinski

Jeremy Berg @jeremymberg.bsky.social · 26/01/2025

In the present discussions about NIH and the need for reform, two recurring points I am seeing are: (1) NIH doesn't fund truly high impact research (2) NIH needs to experiment with alternative approaches to peer review, particularly for high risk-high impact research 1/n

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Reposted by Sara Nowinski

Jennifer Groh @jmgrohneuro.bsky.social · 23/01/2025

If you had a study section or similar NIH travel canceled, or indeed if you have not, can you reply with the dates of the meeting and whether it's on or not? Would be good to get a sense of what time period this applies to for now (esp if NIH is muzzled and can't announce it...)

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Reposted by Sara Nowinski

Science Magazine @science.org · 22/01/2025

“The impact of the collective executive orders and directives appears devastating.” scim.ag/40ureTO

scim.ag

Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring

Researchers facing

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Reposted by Sara Nowinski

Thiago Carvalho @cyrilpedia.bsky.social · 23/12/2024

'Using a mouse in which NDI1 is ubiquitously expressed (...) the authors found that the presence of NDI1 prevented the ability of metformin to reduce glucose levels in healthy and obese mice. The inescapable conclusion is that metformin reduces glucose levels via the inhibition of complex I.'

science.org

Meeting metformin again for the first time

New evidence convincingly shows that metformin, a drug that reduces circulating glucose, acts by inhibiting mitochondrial complex I.

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Sara Nowinski @saranowinski.bsky.social · 07/12/2024

My holiday wish this year was one pic of the lab and their +1’s at the holiday party - last year I waited in the photo booth line 3 times and every time we got to the front someone had run off to get a new drink etc. I’m so proud of this group, and love what we have built together!

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Sara Nowinski @saranowinski.bsky.social · 12/05/2024

The lab’s first preprint is live! We explored how mitochondrial proteins get modified by phosphopantetheine (4’PP) in mammals, and found that it’s absolutely required for respiration! Check it out! biorxiv.org/cgi/content/...

biorxiv.org

Mitochondrial Phosphopantetheinylation is Required for Oxidative Function

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

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Sara Nowinski @saranowinski.bsky.social · 20/12/2023

Excited to share the first publication from the lab! MtFAS: coming soon to a metabolism context near you! authors.elsevier.com/a/1iHu15WXUl...

authors.elsevier.com

Client Request ErrorScienceDirect

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Sara Nowinski @saranowinski.bsky.social · 04/11/2023

Very proud of our summer interns including GVSU senior Bio major Morgan Canfield, who presented a poster on her summer research at #WMRUGS today! The lab’s first undergraduate poster!

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