Researchers found that AI-redesigned versions of natural proteins serve as superior starting points to evolve proteins with new functions.

Colorectal cancer is the No. 1 cause of cancer deaths among people under age 50. Here’s what Stanford Medicine experts want people to know.

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Gladstone scientists have developed a thinking microscope that can conduct its own experiments, with the ultimate goal of treating neurodegenerative diseases.

Gladstone scientists developed a new tool to trace how the brain clears “waste,” uncovering surprising new biology about how it keeps itself healthy.

Approaching Alzheimer’s from every angle, Columbia scientists are finding unexpected inroads to this complex disease and forging paths to new treatment possibilities.

A new fabrication method enables large-scale stretchable transistor arrays to run AI algorithms directly on the body, without transmitting data to an external computer

A new study upends long-held view about how DNA is stored, explaining how subtle shifts in gene activity contribute to cancer, aging, and other complex diseases.

Gladstone scientists are developing novel AI models to predict what goes wrong in disease—and how to fix it.

Scientists at Gladstone expanded their retron-based genome editing technology beyond E. coli, showing it works in 15 diverse bacterial species.

The new approach, developed by UChicago PME and Argonne National Laboratory researchers, offers a streamlined and cost-effective pathway toward decarbonization.

Researchers pinpointed distinct genetic sequences, work that could inform therapeutic strategies for chronic inflammation.

Trained on data spanning the human lifespan, a new tool developed at Gladstone can predict genes associated with aging and age-related diseases.

Women develop Alzheimer’s disease at higher rates than men. Stanford Medicine neurologists explain what science knows about why and the many things it doesn’t yet know.

TRPM8, a key cold-sensing protein in nerve cells, activates to send “cold” signals to the brain when exposed to low temperatures or cooling sensations like menthol. New research from UCSF reveals how ...

UCSF scientists found a precise way to turn on cancer-fighting immune cells inside the body. This more potent form of CAR-T has the potential to treat many more cancers.

Right now, in nearly every cell of your body,microscopic machines are copying your DNA. Clusters of proteins glide down each strand of genetic material, racing to assemble a full replica of your genom...

Nephrologist Alan Pao is developing drugs that boost the urine’s citrate, a natural kidney stone blocker, to stop kidney stones from forming.

A collaboration between an engineer and a stroke specialist led to a spinning device that shrinks blood clots to remove them from the brain.

Study reveals how the gut microbiome and diet work together to transform white fat cells into energy-burning beige fat in mice.

For decades, textbooks depicted our genome as a disordered tangle of strands. Developmental biologist Alistair Boettiger is helping prove that wrong.

A new framework that matches vitamins with genetic diseases helped uncover that high-dose vitamin B3 can dramatically extend survival in mice with NAXD deficiency.

New study shows red blood cells act as hidden glucose sponges in low-oxygen conditions, explaining why people living at high altitude have lower diabetes rates and pointing toward new treatments.

Gladstone scientists identified a cellular boundary that guides heart development and revealed how disrupting it can lead to holes in the heart’s wall.

The molecules mimic a gene variant that protects against Crohn’s, demonstrating a roadmap for using genetics to develop therapies for inflammatory bowel disease and other chronic inflammatory disorder...

UCSF researchers showed that estrogen can turn on pain signals in the gut, offering new insights into conditions like irritable bowel syndrome, especially for women.

Scientists at Gladstone show the new method could treat the majority of patients with Charcot-Marie-Tooth disease.

Your skin is in a constant state of reinvention. Every month, your body sheds and regenerates its entire outer layer—a complete turnover powered by tiny, tireless stem cells. These same cells spring i...

The new theoretical research by UChicago PME and ICTP researchers has implications for melting permafrost and climate change

Columbia researchers are stretching the limits of what is possible for kidney, heart, and liver transplants, pioneering ways to expand the organ supply and avoid lifelong immunosuppressant drugs.

QnAs with Graham F. Hatfull

A new study from Gladstone Institutes strengthens the links between energy breakdown in cells and the onset of Parkinson’s, potentially illuminating new paths for treatment.

Scientists learn to fine-tune a gene that is centrally involved in regulating the immune system, offering potential clues for future autoimmunity and cancer treatments.

UChicago PME researchers built a fully automated system to optimize physical vapor deposition—a process used to make thin films for electronics.

“The phrase ‘Sugar feeds cancer’ is a dangerous statement,” says Stanford Medicine oncology dietitian Erika Connor. “It switches people’s anxiety on and sets them up for misinformation and panic.”

After decades of mystery, Gladstone researchers identify a gene that can derail heart formation—and show that fixing it prevents the problem in mice.

Stanford Medicine experts are developing innovative approaches to preventing, diagnosing and treating chronic diseases so people can live healthier lives.

New research shows that the surrounding cells and tissues of the ovary play a crucial role in how eggs mature and how quickly fertility wanes.