Mit tiefer Trauer nehmen wir Abschied von unserem Kollegen Professor Ralf Seidel. Er ist am 17. Juli 2026 plötzlich und völlig unerwartet verstorben. Sein Tod hinterlässt eine große Lücke. Wir vermiss...

Prof Aaron Newman and I discuss a blood test to assess the tumor microenvironment

Two scientists.Two crystallographers.Both successful, but one died young after her most significant discovery was snatched from her, while the other lived to a ripe old age after a string of ground-breaking discoveries and a Nobel Prize. The former, Rosalind Franklin, is a household name. But the latter, in spite of the foundational importance of her work, has always remained on the fringe of our cultural perception: Dorothy Crowfoot Hodgkin (1910-1994).  It is one of the truly frustrating thing

Two new studies add to a remarkable body of evidence for benefit

YouTube video by Universität Jena

The communication hinge, found in type IV ABC transporters, forms a bidirectional communication between ATP- and substrate-binding sites. This is an unexplored allosteric pathway critical for function...

Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialisation of antibiotics influenced their evolution is limited by a paucity of data predati...

Artificial base-pairs expand the genetic alphabet and allow for site-specific labeling, for example with fluorophores or spin labels, thereby enhancing the capabilities of biomolecular sensing. We…

The COVID pandemic likely began when the virus jumped from animals to humans, and didn’t start in a lab. But false narratives continue to circulate.

The starting point of this study is the solid state structure of a complex between human carbonic anhydrase II (HCAII) and a helically folded tetradecaamide aromatic foldamer with a nanomolar HCAII li...

Toll-like receptors (TLRs) 7 and 8 detect RNA degradation products to sense infection. However, modified nucleosides common in self-RNA—most notably pseudouridine—evade recognition. This study finds t...

Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens...

Most of the available fluorogenic RNA approaches emit visible fluorescence, and there is a need for tools working at longer wavelengths. Here, the authors identify and modulate red fluorescent protein...

Listen now (49 mins) | A pioneer and Nobel laureate for advancing the biology of RNA has a new book THE CATALYST

When dealing with pseudoscience, the devil is in the detail - in this case, narrowing down a specific

Dr. Peter Hotez is a vaccination expert who has nothing to do with COVID. The GOP's COVID committee just put him in its crosshairs -- but why?