Reposted by romain derelle
@rom12relle.bsky.social @johnlees.bacpop.org & Chindelevitch present kamino, a reference- and alignment-free method that rapidly builds amino acid phylogenomic alignments directly from proteomes.
🔗 doi.org/10.1093/molb...
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doi.org
kamino: fast proteome-wide variant calling for amino acid phylogenomics
Abstract. Amino acid-based phylogenetics usually relies on first clustering and aligning orthologous proteins. This approach is powerful but computationall