iiinova — where your digital self keeps evolving

Pierre Peterlongo @pierrepeterlongo.bsky.social · 09/07/2026

1/ 🧬 & 🖥️ New tool: kmhelpers — a Python toolkit dedicated to kmindex, automating the building, updating & querying of large-scale k-mer genomic indexes. Turning raw sequencing samples into a fast, size-optimized search engine — without needing to be a Bloom-filter expert. 🧵

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 08/07/2026

Might be useful. Here is a short blog entry describing a tool that annotates a PDF using a text file. I couldn't find anything that simply does this single task, so I created this. Blog post: pierrepeterlongo.github.io Git repo: github.com/pierrepeterl...

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Heng Li @lh3lh3.bsky.social · 28/06/2026

minibwa v0.3 released with a few minor bug fixes and two missing bwa-mem features (XA tag for secondary hits and option -H to inject header lines). Also added the "mem" subcommand to mimic "bwa mem" CLI to some extent. github.com/lh3/minibwa/...

github.com

Release Minibwa-0.3 (r391) · lh3/minibwa

Notable changes: New feature: added the mem subcommand to mimic the bwa-mem command-line interface (CLI). Most input/output options and commonly used options are retained; unsupported or incompat...

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Ben Langmead @benlangmead.bsky.social · 22/06/2026

Movi 2 has appeared (as an advance article) in Bioinformatics 🧬 Faster, leaner pangenome queries — half the memory of Movi 1, ~30% faster. Paper: academic.oup.com/bioinformati... Code: github.com/mohsenzakeri/Movi (1/6)

academic.oup.com

Validate User

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 11/06/2026

Happy to see that K2Rmini was recommended today by PCI Mathematical & Computational Biology. "quickly evaluate whether an arbitrary sequence has a number of k-mer [of interest] matches above or below a threshold." by @imartayan.bsky.social and colleagues: www.biorxiv.org/content/10.1...

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 03/06/2026

🌎 🧬 🖥️ logan-search.org the tool to query all SRA sequences (Dec 2023 snapshot) — just got major updates. Here's what's new. 🧵 1/12

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Bioinformatics Advances @bioinfoadv.bsky.social · 07/05/2026

🔍 New paper in Bioinformatics Advances: "Kaminari: A frugal colored index for approximate k-mer queries" Read it here: doi.org/10.1093/bioadv/vbag120 Authors include: @yhhshb.bsky.social, @yoann.bsky.social, @robp.bsky.social, @pierrepeterlongo.bsky.social, @jermp.bsky.social

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 21/11/2025

Good Friday Evening news: we updated back_to_sequences (find the origin of kmers) - Faster - Can consider multiline fasta files - Much easier installation: see github.com/pierrepeterl...

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Rob Patro @robp.bsky.social · 09/10/2025

The Metagraph paper is out in Nature; it showed up in my feeds today! Congratulations to Mikhail Karasikov, @gxxxr.bsky.social, @akkah21.bsky.social and all of the other authors (whom I'd love to follow on Bluesky if I can find you ;P) www.nature.com/articles/s41...

nature.com

Efficient and accurate search in petabase-scale sequence repositories - Nature

MetaGraph enables scalable indexing of large sets of DNA, RNA or protein sequences using annotated de Bruijn graphs.

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Jim Shaw @jimshaw.bsky.social · 08/09/2025

Preprint out for myloasm, our new nanopore / HiFi metagenome assembler! Nanopore's getting accurate, but 1. Can this lead to better metagenome assemblies? 2. How, algorithmically, to leverage them? with co-author Max Marin @mgmarin.bsky.social, supervised by Heng Li @lh3lh3.bsky.social 1 / N

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 04/09/2025

❗ I clearly consider this result as THE most important result achieved over this last decade for exploiting and democratizing genomic data. I think there will be a "before" and an "after" logan and logan-search github.com/IndexThePlan... logan-search.org Have a look at this thread

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 27/05/2025

📜 Excited to share insights from our recent paper: "Kaminari: a resource-frugal index for approximate colored k-mer queries". The study aims to efficiently identify documents containing a query string, focusing on DNA strings. www.biorxiv.org/content/10.1... 🧬 🖥️ 1/8

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 18/03/2025

Maybe the simplest idea to decrease overestimations of a counting bloom filter. A trivial observation + 10 lines of code. I'm surprised it has not been described before. Please comment if this is not the case. Blog post here: pierrepeterlongo.github.io/2025/03/17/m... 🧪🧬🖥️

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 30/01/2025

Today I wanted to know the number of unique 27-mers in the hg38 human genome (spoiler there are 2.49 billion). I found no tool for doing this. So I wrote that github.com/pierrepeterl... It may help. Please use it / improve it. 🧬💻 #bioinformatics

github.com

GitHub - pierrepeterlongo/unique_kmer_counter: Count number of unique kmers from fasta or fasta.gz files

Count number of unique kmers from fasta or fasta.gz files - pierrepeterlongo/unique_kmer_counter

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Workshops @evomics.bsky.social · 08/01/2025

We are back in the Town Theatre for a great lecture on Alignment, by @rayanchikhi.bsky.social! 🧬💻 #evomics2025 #genomics #bioinformatics

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 08/01/2025

bsky.app/profile/pier... Applications for this position are still open. If you're passionate about large-scale science, we'd love to hear from you. 🧬 & 🖥️

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 12/12/2024

🚨🚨🚨 We are hiring 🚨🚨🚨 After the creation of logan-search (see: bsky.app/profile/pier...) we propose a 2-years engineer position for continuing the development and optimizations. With @rayanchikhi.bsky.social and @tlemane.bsky.social Details + applications: recrutement.inria.fr/public/class...

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recombseq.bsky.social @recombseq.bsky.social · 11/12/2024

🚨 Call for Papers: RECOMB-seq 2025 🚨 🗓️ Dates: April 24-25, 2025 📍 Location: Seoul, South Korea Key deadlines: 🔹 Abstract registration: Jan 24, 2025 🔹 Submission: Jan 31, 2025 More details: recomb-seq.github.io/papers/

recomb-seq.github.io

Call for Papers

RECOMB-seq is the RECOMB Satellite Conference on Biological Sequence Analysis

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 12/12/2024

🗓️Tomorrow, Friday December 13, Khodor HANNOUSH, from the @genscaleteam.bsky.social team, will defend his thesis entitled “Dynamic Pan-genome Graphs”. Details by following this link: www.irisa.fr/date/2024-12...

irisa.fr

Graphes dynamiques de pangénome | le site web de l'IRISA

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 04/12/2024

Amazing ideas here www.biorxiv.org/content/bior... from @yoann.bsky.social and collaborators. Reorganize minimizers to allow kmers dichotomic search. That's brilliant. #bioinformatics 🧬🖥️

Toy example of the AAAAAAA bucket associated to four super-k-mer turned into their interleaved representation.

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Rob Patro @robp.bsky.social · 12/11/2024

I made a starter pack for algorithmic genomics. It's certainly incomplete, but already has a ton of awesome peeps. Let me know if you know people I should add (with a focus on algorithms and data structures in genomics) go.bsky.app/TRWCnZs

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Pierre Peterlongo @pierrepeterlongo.bsky.social · 11/11/2024

🧬🔍There are 50 petabases of freely-available DNA sequencing data. We introducing Logan Search which allows you to search for any DNA sequence in minutes, bringing Earth’s largest genomic resource to your fingertips. 🏔️ logan-search.org 🏔️ #Genomics #Bioinformatics #OpenScience

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