iiinova — where your digital self keeps evolving

Johannes Rebelein @rebeleinlab.bsky.social · 07/03/2026

Thank you Julia! Looking forward to working with you!

Johannes Rebelein @rebeleinlab.bsky.social · 06/03/2026

We are currently recruiting PhD students, postdocs, and a group leader to join the Institute. If you’re interested, please send me a personal message or email your CV and a brief motivation letter to: johannes.rebelein@hhu.de.

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Johannes Rebelein @rebeleinlab.bsky.social · 06/03/2026

I’m deeply grateful to all my mentors, PIs, colleagues, and collaborators for their support and for helping make this possible. I’m truly excited to build my new lab at Forschungszentrum Jülich and shape IMET’s next chapter.

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Johannes Rebelein @rebeleinlab.bsky.social · 06/03/2026

A childhood dream has come true – I was appointed Full Professor for Sustainable Biotechnology at the University of Düsseldorf @hhu.de : tinyurl.com/f43s74hp and as Director of the Institute for Molecular Enzyme Technology (IMET, www.iet.uni-duesseldorf.de/en/) at FZ Jülich @fz-juelich.de .

tinyurl.com

Mathematisch-Naturwissenschaftliche Fakultät

Heute ernannte Rektorin Prof. Dr. Anja Steinbeck den Biotechnologen Dr. Johannes Rebelein zum W3-Professor für Nachhaltige Biotechnologie. Rebelein wird damit auch Direktor des Instituts für Molekular...

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Julia Frunzke @frunzkelab.bsky.social · 06/03/2026

Welcome to our new colleague Johannes Rebelein, head of the Institut of Sustainable Biotechnology @hhu.de and our new colleague at the Institute of Bio- and Geosciences 1 @fz-juelich.de. Welcome to @mibinet.bsky.social! www.chemie.hhu.de/en/latest-ne...

chemie.hhu.de

Mathematisch-Naturwissenschaftliche Fakultät

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Fidel Ramírez-Amador @fidelormz.bsky.social · 08/12/2025

Last Friday was the defense of my PhD thesis entitled "Structural basis of anaerobic enzymes mediated by noncanonical metalloclusters" after 4 yrs at the @synmikro.bsky.social 🎓🎓 Big thanks to my supervisor @schullerjm.bsky.social and the whole Schuller lab for their continuous and massive support!

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Johannes Rebelein @rebeleinlab.bsky.social · 01/11/2025

Very cool story about the efficient transport and incorporation of non canonical amino acid!

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Johannes Rebelein @rebeleinlab.bsky.social · 23/10/2025

and Gabriella T. Heller, Simone Prinz, @georghochberg.bsky.social and Antonio Pierik.

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Johannes Rebelein @rebeleinlab.bsky.social · 23/10/2025

This is outstanding work by Ana Lago Maciel and all collaborators involved: @jessicacsfla.bsky.social, Jan Zarzycki, Charlie Buchanan, Tristan Reif-Trauttmansdorff, Frederik Schmidt, Stefano Lometto, Nicole Paczia, @schullerjm.bsky.social , @dflemminghansen.bsky.social 🧪

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Johannes Rebelein @rebeleinlab.bsky.social · 03/07/2025

Great collaboration with @lennartschada.bsky.social on an #enzyme converting the #plastic component ethylene glycol and to a feedstock chemical for microbes. Offering new ways to use plastic biotechnologically. 🧪

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Johannes Rebelein @rebeleinlab.bsky.social · 03/07/2025

I am honored and excited that our research on #nitrogenases and the conversion of #CO2 to hydrocarbons is highlighted in the Yearbook 2024 of the Max Planck Society, see page 29. An English and a German version of the Yearbook are available in www.mpg.de/13631298/yea....

mpg.de

Yearbook Highlights

The Yearbook Highlights of the Max Planck Society

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Johannes Rebelein @rebeleinlab.bsky.social · 13/06/2025

A must read for anybody interested in the evolution of life and how to construct phylogenies using structures. Outstanding work by @georghochberg.bsky.social and co-worker. Congrats!

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georghochberg.bsky.social @georghochberg.bsky.social · 11/06/2025

New paper from the lab from Sriram Garg in my group. We introduce a general substitution matrix for structural phylogenetics. I think this is a big deal, so read on below if you think deep history is important. academic.oup.com/mbe/advance-...

academic.oup.com

A general substitution matrix for structural phylogenetics.

Abstract. Sequence-based maximum likelihood (ML) phylogenetics is a widely used method for inferring evolutionary relationships, which has illuminated the

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Johannes Rebelein @rebeleinlab.bsky.social · 01/06/2025

Leveraging spectroscopic and structural approaches we obtained new insights into the role of #ferredoxins in N2 fixation. Just published in Chemistry – A European Journal: doi.org/10.1002/chem...! Great work by Holly Addison. Fantastic collaboration with Antonio Pierik on the EPR characterization.

doi.org

Two Key Ferredoxins for Nitrogen Fixation Have Different Specificities and Biophysical Properties

Two ferredoxins, FdC and FdN, are collectively essential for the process of nitrogen fixation by the iron nitrogenase in R. capsulatus. We explore the biophysical factors, through spectroscopic and s....

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Wim Meijer @wimgmeijer.bsky.social · 04/05/2025

The National Climate Assessment — already in the works for months — was gutted earlier this week, when President Trump’s administration dismissed hundreds of scientists working on it.. The National Nature Assessment was cancelled on his first day back in office.. 🧪🦠 www.nature.com/articles/d41...

nature.com

Trump gutted two landmark environmental reports — can researchers save them?

Scientists working on disrupted national climate and nature assessments aren’t giving up.

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David Ho @davidho.bsky.social · 04/05/2025

I think a lot about what Carl Sagan said in one of his final interviews.

"WE'VE ARRANGED A society based on science and technology, in which nobody understands anything about science technology. And this combustible mixture of ignorance and power, sooner or later, is going to blow up in our faces. Who is running the science and technology in a democracy if the people don't know anything about it?"
"Science is more than a body of knowledge, it's a way of thinking. A way of skeptically interrogating the universe with a fine understanding of human fallibility. If we are not able to ask skeptical questions, to interrogate those who tell us that something is true, to be skeptical of those in authority, then we're up for grabs for the next charlatan, political or religious, who comes ambling along."

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Martin Thanbichler @thanbichlerlab.bsky.social · 01/05/2025

*** Only a few days left to apply *** Postdoc position at the University of Marburg (Germany), funded within our ERC Advanced Grant "C-SWITCH" Spatiotemporal regulation of cellular processes by CTP-switches in bacteria Apply by 04 May: stellenangebote.uni-marburg.de/jobposting/2...

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Tom Ellis @proftomellis.bsky.social · 02/05/2025

My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA. www.imperial.ac.uk/jobs/search-...

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Johannes Rebelein @rebeleinlab.bsky.social · 03/05/2025

Exciting work by Ribbe & Hu lab demonstrating the in vivo reduction of N2 by L-cluster containing Nif(EN)2 inside E. coli: www.science.org/doi/10.1126/... This finding suggests a smaller minimal gene set for the heterologous expression of #nitrogenase and an easier route to synthetic #N2-fixation

science.org

Heterologous synthesis of a simplified nitrogenase analog in Escherichia coli

Heterologous synthesis of a nitrogenase analog (NifH/NifEN) in E. coli enables N2 reduction and incorporation of N into biomass.

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Johannes Rebelein @rebeleinlab.bsky.social · 21/04/2025

This title is at best misleading. The word fertilizer probably suggests to most readers that fungi can fix molecular nitrogen (N2) to ammonia (NH3),which is not the case. So the impact of that finding is debatable...

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Reinhard Steurer @steurer.bsky.social · 20/04/2025

Gab es dazu wirklich KEINE Berichterstattung? Eine Google-News Suche zu CO2-Konzentration liefert nur Ergebnisse zu einem UN-Bericht aus 2024. Keine Studie, keine News? Außer natürlich bei BIP, Inflation, Arbeitslosigkeit... 😬 Bitte gerne Links darunter posten.

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Chris Greening @greening.bsky.social · 20/03/2025

Energy from air? No problem! In our new preprint, we reconstitute the machinery that allows microbes to endure starvation. By using the trace amounts of hydrogen in air alone, they produce plenty of chemical energy (2 ATP) to get by. The only byproduct? Water. www.biorxiv.org/content/10.1...

biorxiv.org

Hydrogenase-driven ATP synthesis from air

All cells require a continuous supply of the universal energy currency, adenosine triphosphate (ATP), to drive countless cellular reactions. The universally conserved F1Fo-ATP synthase regenerates ATP...

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Ben Engel @cellarchlab.com · 06/01/2025

Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍 Preprint📜: www.biorxiv.org/content/10.1... A short thread🧵👇

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Johannes Rebelein @rebeleinlab.bsky.social · 19/04/2025

This is an excellent explanation about the implications of finding #nitrogenase #metalloclusters in the MCR activation complex

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Fidel Ramírez-Amador @fidelormz.bsky.social · 16/04/2025

I'm truly excited to announce our new publication in @nature.com unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to @rnfr2d2.bsky.social for the fantastic illustration! LINK: www.nature.com/articles/s41...

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cryoEM papers @cryoempapers.bsky.social · 17/04/2025

Structure of the ATP-driven methyl-coenzyme M reductase activation complex pubmed.ncbi.nlm.nih.gov/40240609/ #cryoEM

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Johannes Rebelein @rebeleinlab.bsky.social · 30/03/2025

Had a blast at VAAM 2025 in Bochum @vaam-microbes.bsky.social. Holly Addison and Frederik Schmidt gave fantastic talks about our work electron transport to #nitrogenase and nitrogenase #catalysis

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Sven T. Stripp @stripplab.bsky.social · 01/02/2025

Forgot to tag @jamesbirrell.bsky.social‼️

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Johannes Rebelein @rebeleinlab.bsky.social · 31/01/2025

Very proud to see my first PhD student defend his thesis @mpimicrobiomarburg.bsky.social ! Congrats to Leonard Ernst 🎊🍾🎉🥳

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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 26/01/2025

Ten simple rules for developing good reading habits during graduate school and beyond To me, the most important are: Read often, read broadly (incl. older papers and outside your field), and learn to read some papers in detail and others more superficially (and quickly)

Ten simple rules for developing good reading habits during graduate school and beyond by Marcos Méndez
1: Develop the habit of reading on a daily basis
2: Read thoroughly to build a sound background understanding of your topic
3: Do not ignore the pillars of your discipline; read the classics
4: If you have to get familiar with a new topic, consider reading in chronological order
5: Avoid narrow-mindedness by reading beyond your discipline
6: Create a list of relevant journals
7: Not all interesting stuff will appear in articles; read books
8: Use a reference manager to keep track of your literature
9: Keep a long-term review for your own use as a way to remember what you read
10: Build your own library to make yourself independent and inspire others

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Lee Sweetlove @leesweetlove.bsky.social · 24/01/2025

www.nature.com/articles/s41... They "identified many highly conserved positions that tolerate mutation and rare mutations that improve CO2 affinity. These data indicate that non-trivial biochemical changes are readily accessible" #PlantScience

nature.com

A map of the rubisco biochemical landscape - Nature

A massively parallel assay developed to map the essential photosynthetic enzyme rubisco showed that non-trivial biochemical changes and improvements in CO2 affinity are possible, signposting further e...

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Johannes Rebelein @rebeleinlab.bsky.social · 09/01/2025

Two exciting papers about the the protection of nitrogenases from O2 by the ferredoxin Shethna protein II from the Tezcan doi.org/10.1038/s415... and Einsle doi.org/10.1038/s415... labs were published today by @nature.com. Surprisingly both papers reveal superstructures of nitrogenase filaments.

doi.org

Structural basis for the conformational protection of nitrogenase from O2 - Nature

Cryo-electron microscopy of Azotobacter vinelandii FeSII–nitrogenase reveals a core complex of molybdenum–iron proteins (MoFePs), iron proteins (FePs) and FeSII, in which FeSII mediates interactions w...

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