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Rob Denton

@rddenton.bsky.social
1.8K followers 1.7K following 186 posts

Bio Professor | scientist (genomics, evolution, conservation), educator, perpetual student | he/him | posts don't represent employer | dentonlab.org

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Reposted by Rob Denton
Joe Hanly @hanliconius.bsky.social · 22/09/2026
I hate to do this with real data, but this is a persistent data vis issue in chromosome synteny riparian plots that we Need to get better at. Left, a synteny plot published today. Right, a rearranged version with exactly the same gross arrangement but with reordered chromosomes:
chromosome synteny riparian plot in which every chromosome has crossing lineschromosome synteny plot in which no chromosomes have crossing lines. The underlying structure is identical.
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Rob Denton @rddenton.bsky.social · 23/09/2026
Said "Do you think Edward Norton is actually genetically related to Pocahontas or what?" while teaching today. First time sentence for me.
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Rob Denton @rddenton.bsky.social · 17/09/2026
Tonight at our weekly pick-up hockey skate, a guy plugged his phone into the PA system and cued up a playlist of all songs from Tony Hawk's Pro Skater (in order!). What a night.
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Jeffrey Mervis @policyhound.bsky.social · 15/09/2026
A deep dive into the memo that marks the end of how NSF has done business for 76 years www.science.org/content/arti...
science.org
NSF memo implementing Trump’s ‘golden age’ of science unsettles researchers
New document emphasizes support for White House priorities over curiosity-driven ideas
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Rob Denton @rddenton.bsky.social · 15/09/2026
New lab art getting framed. What a privilege to work with talented people who think this kind of thing is a perfectly good use of their time.
A watercolor drawing of a salamander (probably genus Ambystoma) with a cowboy hat on, standing in front of some coiled rope.
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Rob Denton @rddenton.bsky.social · 14/09/2026
Boosting this back out there. Just a couple weeks to apply!
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Jake Grumbach @jakemgrumbach.bsky.social · 09/09/2026
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Colin Carlson @colincarlson.bsky.social · 08/09/2026
If this is true, it’s an interesting warning for scientists using LLMs: there are human beings on the other side of the screen who may not only exploit backdoor access to your discoveries, but also start talking like old timey mobsters (“Why would you ruin your career?”) as they do it 🙃
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Maurine Neiman @maurineneiman.bsky.social · 03/09/2026
Terrific article in @quantamagazine.org about polyploidy and featuring our snails, along with some amazing other scientists! ❤️🐌🧬 www.quantamagazine.org/genome-dupli... @johnlogsdon.bsky.social @chelseahiggins.bsky.social @kylemcelroy.bsky.social @peterdfields.bsky.social @jsharbro.bsky.social
quantamagazine.org
Genome Duplication Is a Radical Evolutionary Gamble | Quanta Magazine
By doubling their entire genome, organisms can evolve extremely rapidly — or they can lose it all. New studies reveal how to survive the high-risk, high-reward evolutionary event.
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Yves Clément @yvesclement.bsky.social · 07/09/2026
A banana genome paper *whithout* a banana-shaped Venn diagram
static.klipy.com
Hot Fuzz: Nicholas Angel Says 'Shame'
ALT: Hot Fuzz: Nicholas Angel Says 'Shame'
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Karolina Heyduk @kheyduk.bsky.social · 24/08/2026
New NSF BIO solicitation says expected number of awards is 250-300. Historically, the number of awards is closer to 800-1000 for the Directorate of Bio Sciences: grantwitness.org/nsf/analyses... Unless I'm missing large, non-core programs, this seems really not good?
grantwitness.org
Agency Pulse: Grantmaking at NSF
An independent, up-to-date, grant-level record of federal science funding disruptions in the United States.
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Stand Up for Science! @standupforscience.net · 24/08/2026
🚨WARNING🚨 Today is the LAST DAY to leave your public comment on the NSF Proposal. The Proposal implements some of Vought's Science-Destroying OMB Proposal plans in advance: zurl.co/9nywR Leave your public comment TODAY using our guide & tool: fight2win.standupforscience.net/campaign/Pro...
fight2win.standupforscience.net
Stand up for Science
Stand up for Science
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Jeremy Yoder says no war @jbyoder.org · 23/08/2026
This is as good a time as any to say that I'm about to start as an Associate Editor at @asn-amnat.bsky.social, and I'm as nerdily excited as you might expect
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Noam Ross @noamross.net · 01/08/2026
My comment on NSF-2026-OTR-0001, NSF's obsequious gutting of their own procedures, replacing them with OMB's proposed rules undermining federal grantmaking with their ideological agenda. Need guidance on commenting? @standupforscience.net has you covered: fight2win.standupforscience.net #NSF
Full text at https://gist.githubusercontent.com/noamross/292dee0ff3b9d47e345801cc7796f70c/raw/2f9bde9cdd1ce067bcce6633e7ddaf70bf0db041/2026-07-31-comment-NSF-2026-OTR-0001.txtFull text at https://gist.githubusercontent.com/noamross/292dee0ff3b9d47e345801cc7796f70c/raw/2f9bde9cdd1ce067bcce6633e7ddaf70bf0db041/2026-07-31-comment-NSF-2026-OTR-0001.txt
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Dan Garisto @dangaristo.bsky.social · 20/08/2026
Scoop: For nearly a year, NSF has struggled to make new grants. Now we know that it will not catch up. In fact, NSF will award just 6,100 new grants—a 30% y/o/y decline, itself down from a previous avg. of 11,000+. In fact, the last time NSF awarded so few grants was in the early '80s.
nature.com
Exclusive: NSF set to issue lowest number of new grants in four decades
The US science-funding agency is withholding $1 billion of its budget so that the money can go to a special White House project.
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Rob Denton @rddenton.bsky.social · 19/08/2026
[JOB!] I'm hiring for a really exciting postdoc position. A combination of breeding experiments, conservation genomics, and student mentorship. Room/board at the @amnh.org Southwestern Research Station each summer, 40 months of support, new science building at BSU. Share broadly! ad: bit.ly/4hKaUIL
A human hand holds a medium sized green frog with distinct gray spots and yellow eyes. This is a Chiricahua Leopard Frog, a threatened species native to the southwest US and Mexico.
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Anna Allen @akallen10.bsky.social · 17/08/2026
New NSF BIO solicitation is live.... this replaces the previous IOS, MCB, DEB solicitation www.nsf.gov/funding/oppo...
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Aramati Casper @aramaticasper.bsky.social · 13/08/2026
Why is there "no consensus" about sex in biology? Turns out, we're using seven different concepts. In "Evolution, development and the incoherence of sex" we name & elucidate these concepts. With Karen Warkentin and Jay Falk @jjinsing.bsky.social @sicbjournals.bsky.social doi.org/10.1093/icb/...
The cover of the article, in Integrative and Comparative Biology. The image caption is "Examples of seven biological phenomena sometimes called sex and the evolutionary relationships among them. The seven sex concepts are depicted with images: 0) horizontal gene transfer, 1) meiosis and syngamy, 2) anisogamy, 3) the gametes produced by an individual, 4) traits often associated with gamete production, 5) processes that bring gametes in proximity to facilitate syngamy, 6) processes/behaviors/traits derived from sex5.
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Matthew Hahn @3rdreviewer.bsky.social · 31/07/2026
Very cool pair of papers demonstrating little link between amount of additive genetic variation and amount of nucleotide variation within species: journals.plos.org/plosbiology/... www.pnas.org/doi/10.1073/...
journals.plos.org
Levels of additive genetic variation vary substantially between species
Adaptive potential determines how populations respond to environmental change. This study compiles evolvability estimates from over 170 multicellular species, revealing substantial variation across th...
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Molecular Biology and Evolution @molbioevol.bsky.social · 29/07/2026
Kayhani et al. find that introgression of warm-adapted alleles was largely successful despite the risk of introducing mitonuclear incompatibilities that could result from genome-wide shifts toward the paternal allele in Tigriopus californicus. 🔗 doi.org/10.1093/molbev/msag158 #societyjournal
doi.org
Introgression of thermal tolerance alleles drives adaptation despite risk of mitonuclear conflict
Abstract. Hybridization may offer a form of genetic rescue from warming temperatures through the introgression of heat-adapted alleles from a high-toleranc
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Janina Rinke @jannelrinke.bsky.social · 02/07/2026
Excited to share that our paper on Horizontal Gene Transfer is now out in its final form in @gigascience.bsky.social! 🥳 By analysing 163 high-quality ant genomes, we show that HGT from bacteria is widespread across the ants and likely has adaptive functions! doi.org/10.1093/giga... 🐜📸: Alex Wild
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Jeremy Yoder says no war @jbyoder.org · 28/07/2026
Finally posted an ad for the postdoc position on my new NSF-funded project—come help build a new method to study plants' responses to environmental variation in space and over time, and figure out interesting ways to use it! Apply by 23 August to ensure consideration. Details: buff.ly/qTvaqvD
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Plant Science Spotlight @plant-sci.bsky.social · 13/06/2026
Don’t reach for ChatGPT Images or Nano Banana as your first option when creating scientific images There are multiple free and open-source images, icons, and tools for creating scientific illustrations. #plantscience @stephenturner.us blog.stephenturner.us/p/free-open-...
blog.stephenturner.us
Free and open-source images, icons, and tools for creating scientific illustrations
Phylopic, NIH Bioart, Bioicons, Scidraw, Open Science Art, Health Icons, Servier Medical Art, Biodiversity Heritage Library, the Noun Project, Segment Anything, Excalidraw, draw.io, Biographics
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Daniel Bolnick @danielbolnick.bsky.social · 14/07/2026
I often give similar advice to my former postdocs / students as they begin faculty jobs: the first year or two are really really hard. It gets much better and is worth it. The successful senior faculty had shitty first years too.
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Dr. Arun Sethuraman @arunsethuraman.bsky.social · 11/07/2026
Hey team - it’s looking very likely that I’ll be hiring not one but two four year postdocs! We’re a fun lab with tons of theoretical and applied pop gen projects - broadly in polyploid, conservation, and human evo. Competitive salary, sunny San Diego! Do share with your about to defend grads!
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Steven Salzberg @stevensalzberg.bsky.social · 07/07/2026
Our new genome annotation method relies almost entirely on transcriptome and alignment evidence, and as a result outperforms pretty much all other de novo pipelines. Check out the just-published paper led by Aleksey Zimin: rdcu.be/frSOg
rdcu.be
Efficient evidence-based genome annotation with EviAnn
Nature Methods - EviAnn surpasses existing genome annotation methods by leveraging gene expression and protein sequence homology evidence to achieve higher accuracy and efficiency.
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Rob Denton @rddenton.bsky.social · 03/07/2026
A former uni president of mine came from K-12 background and was supposedly critical of faculty teaching loads because we weren't teaching all day, M-F, like high school. And research production was part of our promotion and tenure! Just a wild disconnect between big money admin and faculty.
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Rob Denton @rddenton.bsky.social · 02/07/2026
I'm pro Neil and all he stands for.
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Rob Denton @rddenton.bsky.social · 30/06/2026
Happy Fiscal Year's Eve to all that celebrate and/or hate it
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Prosanta Chakrabarty @prosanta.bsky.social · 26/06/2026
Y'all - the Smithsonian is hiring three new curators - herpetology, ichthyology, and ornithology! Notably, this is a 2nd fish curator position - i.e., not the same as the one advertised last month. So if you applied for that one apply again. www.usajobs.gov/job/873849000
Curator of Vertebrates

Smithsonian’s National Museum of Natural History currently has openings for three early-career Research Curators in Vertebrate Zoology, one each from the disciplines of ornithology, herpetology and ichthyology. The Department of Vertebrate Zoology seeks candidates with demonstrated expertise in, and a commitment to, collections-based research centered on systematics and evolution of birds, reptiles, amphibians, and fishes. This includes the ability to pursue an original approach to systematics and comparative analyses using, for example, morphology, development, and/or molecular data, and showing evidence of broader impacts or applications in evolutionary biology and/or collections-based ecology, as demonstrated by a record of peer-reviewed publications.

Candidates must have demonstrated the ability to establish an externally funded research program and to contribute to the growth and curation of the collections. Research in the Department is supported by the Museum’s shared laboratories, including the Laboratory of Analytic Biology and the Scientific Imaging facility, among others. The Department’s scientific collections are the largest in the world for fishes, amphibians, and reptiles, and the third largest for birds.

These federal positions will be filled at the GS-12 level, with a starting salary of $102,415, and excellent benefits. The positions are permanent and require a one-year probationary period. 

The official announcement is posted on USAJOBS, where applications must be submitted.
https://www.usajobs.gov/job/873849000

Please be sure to read the announcement and instructions carefully, as the process of applying via USAJOBS is stringent and differs from applying for an academic position. This website offers helpful advice: https://serc.si.edu/careers/tips-applying-federal-jobs

Please contact the Search Committee Chair, Michael McGowen (mcgowenm@si.edu) or the Department Chair, Helen James (jamesh@si.edu) with any questions.
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Kyle T David @kylethedavid.bsky.social · 23/06/2026
From lenticular printing to mounted displays, #Evol2026 is pushing the boundaries of what it means to present a poster
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The New Yorker @newyorker.com · 24/06/2026
Biologists have long wondered how to account for the bewildering array of ways that the world’s life-forms reproduce. But, recently, the study of sex has undergone a sexual revolution of its own. www.newyorker.com/magazine/202...
newyorker.com
What’s the Point of Sex, Anyway?
The world’s life-forms reproduce sexually in a bewildering variety of ways, even though scientists still aren’t sure why they bother.
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Rob Denton @rddenton.bsky.social · 21/06/2026
Bummed to miss #Evol2026. For all those students looking for a position, we're recruiting MS students (polyploid genomics) and a PostDoc (conservation genomics) for next year. Shoot me an email!
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John Hawks @johnhawks.net · 12/06/2026
It is a very challenging position that @neilshubin.bsky.social walks into as leader of @nasonline.org with partisan division over many areas of scientific work. Illuminating interview with @carlzimmer.com as he takes office. www.nytimes.com/2026/06/12/s...
nytimes.com
Neil Shubin on Trusted Science in a ‘Deeply Partisan Age’
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Molly Przeworski @mollyprz.bsky.social · 09/06/2026
Now published: journals.plos.org/plosbiology/...
journals.plos.org
What sets the mutation rate of a cell type in an animal species?
Mutation rates per generation are strikingly similar across germlines of animals and across at least one somatic cell type, suggesting a key role for natural selection in shaping mutation rates. This ...
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American Naturalist / ASN 🐌 @asn-amnat.bsky.social · 08/06/2026
Riddell uncovers that salamanders from different elevations achieve similar plastic responses through distinct molecular mechanisms, offering new insight into how populations may respond (or fail to respond) to environmental change. Read now ahead of print! www.journals.uchicago.edu/doi/10.1086/...
The American Naturalist classic cover
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Andrew Hardaway @andrewhardaway.bsky.social · 05/06/2026
This is an extremely helpful guide for how to discuss this with the lay public. And these people can comment too! Its been really fun to see some of my non-scientist friends and family comment on the register after talking it over with them.
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Rob Denton @rddenton.bsky.social · 05/06/2026
If you are attending #JMIH26 in New Orleans, please consider participating in the mentorship program! This is a *huge* thing for helping first time attendees and growing networks. If you missed it during registration, here is a form for participants (mentors and mentees): forms.gle/ERLGdXdQavzo...
forms.gle
2026 SSAR/JMIH Mentorship Program interest form
The SSAR Mentorship Program has become an important way for meeting attendees to make lasting professional connections. Each mentor is usually matched with 1-2 mentees and given a list of ideas for ...
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Rob Denton @rddenton.bsky.social · 05/06/2026
I like it here because I often (daily?) save things like this that are immediate adds to my teaching resources. I've taught genetic code for years and never once thought to include this.
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Rob Denton @rddenton.bsky.social · 03/06/2026
Dispatches from the lab: outside world is insane, but lab environment is wonderful: fun/rowdy group, lots of support, many interesting projects, ton of learning. Thankful for this job, the $ support to make the science go, and for the privilege to fight for it. Call your reps folks, organize.
A shelf for food and drinks outside of a science lab, showing a diversity of water bottles and lunchboxes, most adorned with playful stickers
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Joanna Masel @joannamasel.bsky.social · 03/06/2026
Our new paper doi.org/10.1098/rspb... on long-term genetic threats to small populations finds that "mutational meltdown" (bad mutations fixing) is less of a problem than "mutational drought" (too few good new mutations) @wmawass.bsky.social @uliseshmc.bsky.social @jeremyjberg.bsky.social 1/5
doi.org
Extinction vortices are driven more by a shortage of beneficial mutations than by deleterious mutation accumulation
Abstract. Habitat loss contributes to extinction risk in multiple ways. Genetically, small populations can face an ‘extinction vortex’—a positive feedback
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José Cerca @naturalselection.bsky.social · 02/06/2026
🧨 New publication out (I think this one is 🌶️ ): Cerca & @stelkens.bsky.social - "The identity crisis of speciation genomics". academic.oup.com/evolinnean/a...
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mara lawniczak @marakat.bsky.social · 29/05/2026
If you are interested in collecting specimens for chromosomal genomes and/or generating chromosomal reference genomes from specimens that were not cold-chain preserved, please read on and share this thread.
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Kevin Bird @stairwaytokevin.bsky.social · 02/06/2026
New post is live! 40 years of race science arguments about brain size & the racial IQ gap, nobody bothered to write down the math or do anything beyond gawk at correlations. I did, walking through the data & formalizing it with the Lande equation. It fares worse than you could even imagine.
open.substack.com
Race on The Brain: why brain-size differences can’t explain the IQ gap
Tackling a popular hereditarian argument
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Matthew Hahn @3rdreviewer.bsky.social · 02/06/2026
Very happy to announce a big new paper from the lab, led by grad students @smishra677.bsky.social and Laia Pomar-Pallarès (in collaboration with @roblanfear.bsky.social). We introduce a new way to study introgression, with accompanying software (DAFT) 1/n 🧵 www.biorxiv.org/content/10.6...
biorxiv.org
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Jeremy Yoder says no war @jbyoder.org · 01/06/2026
NSF really did say it
Screenshot from a Notice of Award email:

AWARD INFORMATION
Award Number (FAIN): 2536007
Award Instrument: Standard Grant
Award Date: 06/01/2026
Award Period of Performance:   Start Date: 06/01/2026     End Date: 05/31/2029
Project Title: RUI: Temporal analysis of reproduction distributed in space to characterize plant populations' responses to environmental variation
Managing Division Abbreviation: DEB
Research and Development Award: Yes
Funding Opportunity: NSF 14-579 Facilitating Research at Primarily Undergraduate Institutions:
Assistance Listing Number(s) and Name(s): 47.074 Biological Sciences (Predominant source of funding for SEFA reporting)

FUNDING INFORMATION
Amount Obligated by this Amendment: $814,012
Total Intended Award Amount: $814,012
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Rob Denton @rddenton.bsky.social · 01/06/2026
[new paper!] All-female, polyploid salamanders are weird: they have 3-4 sets of giant chromosomes, a mitochondria that doesn't match their nuclear genomes, and are made of fewer, bigger cells. We've thought about the consequences of this in lots of ways, stumbling on a neat one during my PhD..(1/n)
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Science Magazine @science.org · 28/05/2026
Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. scim.ag/4nTQ3nq
How animals sense Earth’s magnetic field is one of biology’s enduring mysteries. Researchers have now identified superparamagnetic macrophages in the livers of rock pigeons (Columba livia) to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.

Photo: Andreas Teichmann/laif/Redux
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Kristian G. Andersen @kgandersen.bsky.social · 28/05/2026
The full proposal is now available: public-inspection.federalregister.gov/2026-10817.pdf Some comments / highlights here: bsky.app/profile/kgan... TL:DR - It's exactly as expected. And that's not good, in case that wasn't clear.
public-inspection.federalregister.gov
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Rob Denton @rddenton.bsky.social · 22/05/2026
Fun science remains fun.
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