Sign in

raphmercier.bsky.social

@raphmercier.bsky.social
1.5K followers 288 following 69 posts

#Meiosis4ever. #ChromosomeBiology. Max Planck for Plant Breeding Research.

PostsRepliesMedia
Reposted by @raphmercier.bsky.social
Polina Novikova @pnovik.bsky.social · 16/09/2026
I am happy to present our work @liverworks.bsky.social @robinburns.bsky.social @alisondawnscott.bsky.social on centromeric repeat turnovers, of which we counted three in the Arabidopsis genus:
biorxiv.org
The Nature of Centromeric Repeat Turnovers in the genus Arabidopsis
Centromeres are critical for accurate segregation of chromosomes and are often composed of megabases of tandemly arranged satellite repeats. Yet, despite their conserved function, the DNA sequence of ...
22721
Reposted by @raphmercier.bsky.social
André Marques @amarques.bsky.social · 16/09/2026
Out today in Nature: sex without crossovers. Rhynchospora tenuis makes pollen, fertilises and sets seed, yet 0 crossovers in 10,997 pollen nuclei. Chromosome drive and ~87% seed abortion rebuild the mother's genotype, so the offspring are clones. doi.org/10.1038/s415...
916369
Reposted by @raphmercier.bsky.social
Max Planck Institute for Plant Breeding Research @mpipz.bsky.social · 17/09/2026
📣📣Paper Alert! New paper @nature.com from the Marques group @amarques.bsky.social and colleagues on Rhynchospora tenuis - 🌿a plant that reproduces sexually but has completely lost the reshuffling of DNA🧬 Congratulations! 👏 🥳 Read more👉 www.mpipz.mpg.de/pr-marques-2... www.nature.com/articles/s41...
nature.com
Sex without crossovers mimics clonal reproduction in Rhynchospora tenuis - Nature
Rhynchospora tenuis undergoes obligate, genome-wide achiasmy in both male and female meiosis.
04319
raphmercier.bsky.social @raphmercier.bsky.social · 24/07/2026
An impressive new paper from Kejian Wang’s lab: MiMe+HUAXU=full-penetrant apomixis www.vita-journal.com/vita/EN/10.1... Self-propagating hybrids are a reality!
vita-journal.com
065
raphmercier.bsky.social @raphmercier.bsky.social · 24/07/2026
Hot off the press (so to speak)! Where we described new factors that inhibit meiotic crossovers near centromeres rdcu.be/fvHfe thread👇
rdcu.be
The deSUMOylase SPF2 and the cohesin regulators SGO2 and CTF18 suppress crossovers near centromeres
Nature Plants - Gamboa et al. identified three proteins that restrict meiotic crossovers near centromeres. This finding suggests that cohesion regulation plays a role in this suppression and...
22210
Reposted by @raphmercier.bsky.social
PlantEvolution 🌱🌾 @plantevolution.bsky.social · 28/04/2026
What could be better than seeing a former member of your lab elected to the US National Academy of Sciences @nasonline.org? Huge congrats to Kirsten Bomblies @ethz.ch! Here are the two of us with @thanvisrikant.bsky.social , who was first a PhD student in my lab & then a postdoc with Kirsten.
48510
raphmercier.bsky.social @raphmercier.bsky.social · 16/04/2026
#TodayOnMyBike
000
raphmercier.bsky.social @raphmercier.bsky.social · 15/04/2026
#TodayOnMyBike
000
raphmercier.bsky.social @raphmercier.bsky.social · 02/04/2026
www.sciencedirect.com/science/arti...
sciencedirect.com
Cohesin and its regulation promote monopolar kinetochore orientation at meiosis I in Arabidopsis
The first division of meiosis is unique in its capacity to halve the ploidy of future gametes. To this end, one key innovation compared with mitosis i…
1116
raphmercier.bsky.social @raphmercier.bsky.social · 05/02/2026
#TodayOnMybike #SpringIsComing
020
Reposted by @raphmercier.bsky.social
CNRS Mathématiques @cnrs-insmi.bsky.social · 08/01/2026
Découvrez les 18 nouvelles et nouveaux membres élus à @academiesciences.bsky.social pour l'année 2026 🔎 Communiqué de presse à lire sur ➡️ www.academie-sciences.fr/sites/defaul...
4146
Reposted by @raphmercier.bsky.social
Russ Fischer @superelastic.bsky.social · 23/12/2025
and the winner of the "2025 best thing on Internet" has just arrived neal.fun/size-of-life/ @carlbergstrom.com
neal.fun
Size of Life
From an amoeba to a blue whale
113656
Reposted by @raphmercier.bsky.social
Charlie Underwood @charlieunderwood.bsky.social · 21/12/2025
An early Christmas present from our team for all of the tomato 🍅 & recombination fans: Chromosome-scale Solanum pennellii and Solanum cheesmaniae genome assemblies reveal structural variants, repeat content and recombination barriers of the tomato clade biorxiv.org/content/10.648…
22711
raphmercier.bsky.social @raphmercier.bsky.social · 12/12/2025
Merry Xmas from the department of Chromosome Biology!
060
Reposted by @raphmercier.bsky.social
CEPLAS - Cluster of Excellence on Plant Sciences @ceplas.bsky.social · 09/12/2025
‼️Please RT: The CEPLAS Graduate School call for 2026 is now open! Detailed info on our website: bit.ly/4q19JWk @hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
02335
Reposted by @raphmercier.bsky.social
UC Davis @ucdavis.bsky.social · 08/12/2025
Two researchers at UC Davis have been awarded a VinFuture Prize in recognition of their work developing self-cloning crops, a breakthrough for sustainable agriculture. Read more: ucdav.is/4oJ41Hx
Imtiyaz Khanday and Dr Venkatesan Sundaresan stand next to cloned rice plants in a green house.
0178
raphmercier.bsky.social @raphmercier.bsky.social · 07/11/2025
www.nature.com/articles/s42... Latest from the lab. The conclusion is in the title! Basically, we found that the KMN complex (outer kinetochore) is fully conserved between plants and fungi/animals, showing deep origin. (reminder, you are closer to a mushroom than a mushroom is to a plant.)
nature.com
The composition and structure of the outer kinetochore KMN complex is conserved across kingdoms - Communications Biology
Affinity purification in Arabidopsis identified all key subunits of the outer kinetochore KMN complex. Functional analyses revealed a striking conservation of its composition and organization across k...
12812
Reposted by @raphmercier.bsky.social
François Parcy @flowerwhatelse.bsky.social · 24/10/2025
On mange des OGM tous les jours depuis plusieurs décennies (les plantes obtenues par mutagénèse chimique ou radiative) et ça ne pose aucun problème
1198
Reposted by @raphmercier.bsky.social
PHD Comics @phdcomics.com · 23/10/2025
The Author List
27115
raphmercier.bsky.social @raphmercier.bsky.social · 21/10/2025
Only those who know🐖🎮
061
Reposted by @raphmercier.bsky.social
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 13/10/2025
“The scientific Nobels announced this week underscore that point. All three awards — granted each year in physiology or medicine, physics and chemistry — honored achievements rooted in fundamental research…Decades of inquiry paved the way for the technology, treatments and toys of tomorrow.” 🎁
nytimes.com
Nobel Prizes This Year Offer Three Cheers for Slow Science
13820
Reposted by @raphmercier.bsky.social
Oded Rechavi @odedrechavi.bsky.social · 04/10/2025
Thanking the reviewers
113112
Reposted by @raphmercier.bsky.social
Chloe Girard, PhD @chloegirard.bsky.social · 01/10/2025
This is the work of a tremendous PhD student, Benoit Madec, who did everything in this study (genetics, molecular biology, all the bioinformatics analyses) He defended his PhD on Monday and is now Dr Madec! I am very proud of him and all the work he has accomplished!
Benoît during his PhD defense on Monday!
1101
Reposted by @raphmercier.bsky.social
Chloe Girard, PhD @chloegirard.bsky.social · 01/10/2025
🚨 First pre-print from my team !! TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !
The recombination frequency (cM/Mb) along chromosome 4 of A. thaliana (female meiosis). 

In full hybrids (grey), where polymorphism is distributed all along chromosomes, most crossovers occur in the regions surrounding the Centromere (Cen), and very few at chromosome ends (Tel: telomeres). 

In lines where polymorphism is restricted to chromosome ends (purple), the local recombination rate increases drastically, at the expense of the non-polymorphic regions (yellow).
35119
Reposted by @raphmercier.bsky.social
PHD Comics @phdcomics.com · 14/09/2025
Writing: just add coffee **Hey, my new book comes out on Tuesday! 👉 amazon.com/gp/aw/d/1419764063
010112
Reposted by @raphmercier.bsky.social
Maddy Seale @maddyseale.bsky.social · 22/09/2025
Out First Release in @science.org this week: A large scale analysis of the epigenetics of transposable elements in Arabidopsis shows transgenerational stability www.science.org/doi/10.1126/... #PlantScience
science.org
Transposable elements are vectors of recurrent transgenerational epigenetic inheritance
DNA methylation loss at transposable elements (TEs) can affect neighboring genes and be epigenetically inherited in plants, yet the determinants and significance of this additional system of inheritan...
05018
Reposted by @raphmercier.bsky.social
wcrismani.bsky.social @wcrismani.bsky.social · 11/09/2025
I feel incredibly privileged to share this study on Fanconi anaemia, based on a small but important cohort. This work describes the genetics and clinical outcomes of patients in Australia and New Zealand with a diagnosis of FA. www.sciencedirect.com/science/arti...
sciencedirect.com
Clinical and genetic spectrum of Fanconi anemia in Australia and New Zealand
Fanconi anemia (FA) is a rare genetic condition that predisposes to progressive bone marrow failure, a specific spectrum of malignancies, including he…
175
Reposted by @raphmercier.bsky.social
Zwicker Group @zwickergroup.bsky.social · 10/09/2025
This is a great opportunity to start an independent group in one of the best research environments you could think of!
032
Reposted by @raphmercier.bsky.social
Max-Planck-Gesellschaft @maxplanck.de · 09/09/2025
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
Call for Applications / Ausschreibung
25256
raphmercier.bsky.social @raphmercier.bsky.social · 08/09/2025
www.nature.com/articles/d41... Interesting journalist piece on apomixix. With pieces of MiMe inside :-)
nature.com
Is this the future of food? 'Sexless' seeds that could transform farming
Scientists are tinkering with plant genes to create crops that seed their own clones, with a host of benefits for farmers.
030
Reposted by @raphmercier.bsky.social
Schnittger Lab @schnittger-lab.bsky.social · 25/08/2025
Six more years—plus a lot of blood, sweat, and tears—later, we are thrilled to finally share it: a cytological framework of female meiosis in Arabidopsis! www.biorxiv.org/content/10.1...
biorxiv.org
A cytological framework of female meiosis in Arabidopsis
Female and male meiosis often differ in many aspects, such as their duration and the frequency as well as the positioning of crossovers. However, studying female meiosis is often very challenging and ...
34519
raphmercier.bsky.social @raphmercier.bsky.social · 25/08/2025
Preprint Alert! 🚨🧬 Not one, but two preprints! Meiotic orientation of kinetochore at meiosis is inforced by...[see below] www.biorxiv.org/content/10.1... and Unlocking meiotic crossovers next to plant centromere www.biorxiv.org/content/10.1... #meiosis4ever #everythingisconnected a thread👇
biorxiv.org
Monopolar orientation of kinetochores at meiosis is enforced by COHESINS and their regulators, CENP-C, and the deSUMOylase SPF2
The first division of meiosis is unique in its capacity to halve the ploidy of the future gametes. To this end, one key innovation compared to mitosis is the monopolar orientation of the pairs of sist...
21911
Reposted by @raphmercier.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 12/08/2025
@alisondawnscott.bsky.social et al. use genome data from >400 Arabidopsis lyrata sampled across Eurasia to show it as the most polyploid-rich species complex in Arabidopsis, with multiple origins of autotetraploidy. 🔗 doi.org/10.1093/molbev/msaf153 #evobio #molbio #PlantSky
doi.org
Multiple Autopolyploid Arabidopsis lyrata Populations Stabilized by Long-Range Adaptive Introgression Across Eurasia
Abstract. Abundance of established polyploid lineages varies across lineages, evolutionary time, and geography, suggesting both genetics and environment pl
03315
Reposted by @raphmercier.bsky.social
Nick Desnoyer @nickdesnoyer.bsky.social · 11/08/2025
Introducing the 1,000 Flower Collection 🧬🌹 I’m creating 1,000 genetically designed flowers each crafted with new colors, patterns, and shapes. Here’s how I’m making it happen… and how you can join me on this journey 🧵(1/7)
213667
Reposted by @raphmercier.bsky.social
Thomas Lenormand @thomaslenormand.bsky.social · 12/07/2025
Interested to know more about a new theory relating the #evolution of #sexchromosomes to the rules of #speciation? Check out this paper that we published with Denis Roze in the last issue of #Science. PDF here: www.science.org/stoken/autho...
science.org
A single theory for the evolution of sex chromosomes and the two rules of speciation
Sex chromosomes are involved in three major empirical patterns: (i) Y (or W) chromosomes are often nonrecombining and degenerate; (ii) heterogametic offspring (XY or ZW) from interspecific crosses are...
03718
Reposted by @raphmercier.bsky.social
Valérie Borde @lab-borde.bsky.social · 03/08/2025
www.biorxiv.org/content/10.1...
biorxiv.org
RPA directly stimulates Mer3/HFM1 helicase processivity to ensure normal crossover formation in meiosis
Meiotic crossover formation is critical for generating viable gametes and enhancing genetic diversity. The helicase Mer3 (HFM1 in humans) is a highly conserved factor essential for promoting crossover...
084
Reposted by @raphmercier.bsky.social
The Atlantic @theatlantic.com · 03/08/2025
Scientists have spent decades puzzling over potatoes’ origin story. The answer was juicier than anyone expected, @katherinejwu.com reports.
bit.ly
Potatoes Evolved From … Tomatoes?
Dipping fries into ketchup just got a little more mind-bending.
66720
Reposted by @raphmercier.bsky.social
Max-Planck-Gesellschaft @maxplanck.de · 01/08/2025
Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.
Open Call for Expressions of Interest in Max Planck Directorships:
Expressions of interest can be submitted until 31 October 2025.
1161195
Reposted by @raphmercier.bsky.social
Oded Rechavi @odedrechavi.bsky.social · 22/07/2025
When the professor edits the student's draft
08611
Reposted by @raphmercier.bsky.social
Oded Rechavi @odedrechavi.bsky.social · 28/07/2025
It's not procrastination i'm thinking
1485
Reposted by @raphmercier.bsky.social
Alice Vayssières @alicevayssieres.bsky.social · 18/07/2025
Cette année, les Journées Scientifiques et Techniques (JST2025) du Réseau des Microscopistes INRAE (RµI) sont à Versailles!!! C'est du 5 au 7 novembre 2025 et les inscriptions sont ouvertes !!! 🔬👑✨ @ijpb-versaillescly.bsky.social 👇👇👇 rmui-2025.journees.inrae.fr
244
Reposted by @raphmercier.bsky.social
Jane Langdale 🌱 🌾 @janelangdale.bsky.social · 25/07/2025
For all plant developmental biologists out there - has been orange flowered for 20 years. Will be tracking the pink branch from now on!
Hibiscus plant with two different coloured flowers
9769
raphmercier.bsky.social @raphmercier.bsky.social · 19/07/2025
#TodayOnMyBike
010
raphmercier.bsky.social @raphmercier.bsky.social · 09/07/2025
#TodayOnMyBike
020
Reposted by @raphmercier.bsky.social
Adrián Gonzalo @adriangonzalo.bsky.social · 01/07/2025
Check out the Views & News piece that Joiselle Fernandes and I wrote for @nature.com on the recent work from @amarques.bsky.social and colleagues about one of the most bizarre ways to do meiosis rdcu.be/euabu. Explained for non-experts!
Diagram of two types of reproduction based on their meiosis. A. shows typical meiosis taking place in individuals with two copies of each chromosome (diploids) resulting in both male and female gametes carrying one copy of each chromosome. Fertilization restores the double copy for each chromosome. B. shows Canina meiosis in individuals carrying five copies of each chromosome (pentaploids) where male gametes only carry one copy of each chromosome and female gametes carry four copies of each chromosome. Fertilization restores the five copy for each chromosome.
02413
Reposted by @raphmercier.bsky.social
André Marques @amarques.bsky.social · 02/07/2025
I am super happy to see our dog rose's paper featuring the cover of the July 3rd issue of @nature.com read more here: tinyurl.com/dog-rose
0526
Reposted by @raphmercier.bsky.social
Nature @nature.com · 18/06/2025
Nature research paper: Bimodal centromeres in pentaploid dogroses shed light on their unique meiosis go.nature.com/407PRGm
go.nature.com
Bimodal centromeres in pentaploid dogroses shed light on their unique meiosis - Nature
Insights into the dogrose genome and centromeres explain their ability to achieve stable sexual reproduction.
0278
Reposted by @raphmercier.bsky.social
André Marques @amarques.bsky.social · 18/06/2025
1/7 I am very excited to announce our🌹NEW PAPER OUT IN 𝑁𝐴𝑇𝑈𝑅𝐸!🌹 𝐃𝐑𝐈𝐕𝐄 𝐓𝐎 𝐒𝐔𝐑𝐕𝐈𝐕𝐄: Bimodal centromeres in pentaploid dogroses shed light on their unique meiosis With the Ritz and Kovařík labs we show a potential role for centromeres on 𝘙𝘰𝘴𝘢 𝘤𝘢𝘯𝘪𝘯𝘢 bizarre reproduction! www.nature.com/articles/s41...
nature.com
Bimodal centromeres in pentaploid dogroses shed light on their unique meiosis - Nature
Insights into the dogrose genome and centromeres explain their ability to achieve stable sexual reproduction.
87838
Reposted by @raphmercier.bsky.social
Max Planck Institute for Plant Breeding Research @mpipz.bsky.social · 17/06/2025
🎉 We’re thrilled to share that our director Miltos Tsiantis has been awarded an ERC Advanced Grant @erc.europa.eu for his project CLONAL, which will explore the development and diversity of root suckers. Congratulations! 🌱👏Learn more: bit.ly/43KuvBe #ERCAdG #plantsci
bit.ly
ERC Advanced Grant awarded to Max Planck Director Miltos Tsiantis
Prof. Dr. Miltos Tsiantis, Director at the Max Planck Institute for Plant Breeding Research and head of the Department of Comparative Development and Genetics, receives an Advanced Grant from the European Research Council (ERC). The prestigious funding will support his project CLONAL, aimed at advancing our understanding of clonal reproduction by root sucker formation.
0334
raphmercier.bsky.social @raphmercier.bsky.social · 12/06/2025
#TodayOnMyBike
020