iiinova — where your digital self keeps evolving

Reposted by Adrián Gonzalo

PlantEvolution 🌱🌾 @plantevolution.bsky.social · 28/09/2026

Cool new work from @thanvisrikant.bsky.social & @kbomblies.bsky.social: Chromosomes in #Arabidopsis thaliana neo-polyploids break preferentially at fragile sites that correspond to ancient genome rearrangements #plantscience www.biorxiv.org/content/10.6...

Detection and analyses of aneuploidies in neo-tetraploid A. thaliana. (A) Schematic
representation of how neo-tetraploid F1 were generated through reciprocal crossing of Col-0 and
Ler neo-tetraploid inbreds. See Figure S1A for more details. (B-D) Examples of aneuploidy
detection using sequencing coverage data from three F1 individuals, “Cross_3_Plant_32”,
“Cross_3_Plant_25” and “Cross_38_Plant_01”, respectively (Figure S2, S3). The upper panels
show aneuploidy detection using a read-coverage approach and the lower panels show a
variant-calling based approach. The Ler chromosomes are indicated as L1-L5 (orange) and Col-
0 chromosomes are indicated as C1-C5 (blue). In both panels, every data point represents a
mean value (normalised read coverage / allele frequency) in a 100kb window of the genome.
For the upper panels, sequencing data are mapped to an in-silico hybrid genome that combines
TAIR10.1 (Col-0) and Ler. For the lower panels, the sequencing data are mapped to a Ler
reference genome. (B) Data from a euploid individual with normalised coverage consistent with
two copies of each maternally and paternally inherited chromosome (upper panel), and allele
frequencies clustering around 0.5 when mapped to a Ler reference genome (lower panel). (C)
Data from an individual affected by a full-length aneuploidy – a loss of one Chromosome 2 copy
from Col-0, resulting in a drop in coverage (upper panel) and sharp changes in allele frequency
(lower chromosome) for Chr2. (D) Data from an individual affected by a segmental loss of part
of Chromosome 4 from the Ler parent.

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Reposted by Adrián Gonzalo

André Marques @amarques.bsky.social · 27/01/2026

A new extreme of meiotic evolution: ✔️ 𝗻𝗼 crossovers ✔️ 𝗻𝗼 gene conversion ✔️ 𝗻𝗼𝗿𝗺𝗮𝗹 meiosis & fertility Sex mimics clonality without becoming asexual, in the holocentric multicellular eukaryote 𝘙𝘩𝘺𝘯𝘤𝘩𝘰𝘴𝘱𝘰𝘳𝘢 𝘵𝘦𝘯𝘶𝘪𝘴. more about it: www.biorxiv.org/content/10.6...

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Reposted by Adrián Gonzalo

Thanvi Srikant @thanvisrikant.bsky.social · 15/12/2025

✨Call open for a fully-funded PhD position✨ Looking for an enthusiastic student to join my upcoming Ambizione research group (🌱 Epigenome Diversity Lab 🌱, www.epidiversitylab.org) at ETH Zürich, starting August 2026! Apply here ↘️ jobs.ethz.ch/job/view/JOP... Application deadline: January 31st, 2026

jobs.ethz.ch

PhD position to study epigenomic diversity and altitude adaptation in Arabis alpina

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Reposted by Adrián Gonzalo

Schnittger Lab @schnittger-lab.bsky.social · 25/08/2025

After 12 years… In 2014, a wild idea was born: to follow female meiosis in Arabidopsis in real time. After many trials (including experiments with quirky mutants where female organs developed inside out, and a few other unconventional ideas), we switched gears to image the male side.

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Reposted by Adrián Gonzalo

raphmercier.bsky.social @raphmercier.bsky.social · 25/08/2025

Preprint Alert! 🚨🧬 Not one, but two preprints! Meiotic orientation of kinetochore at meiosis is inforced by...[see below] www.biorxiv.org/content/10.1... and Unlocking meiotic crossovers next to plant centromere www.biorxiv.org/content/10.1... #meiosis4ever #everythingisconnected a thread👇

biorxiv.org

Monopolar orientation of kinetochores at meiosis is enforced by COHESINS and their regulators, CENP-C, and the deSUMOylase SPF2

The first division of meiosis is unique in its capacity to halve the ploidy of the future gametes. To this end, one key innovation compared to mitosis is the monopolar orientation of the pairs of sist...

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Reposted by Adrián Gonzalo

Magdalena Bohutínská @majdabohu.bsky.social · 17/07/2025

1/5 ✨Proud✨ to see our review with Katie Peichel as featured content in Trends_Ecol_Evo, with my beloved alpine lineages of Arabidopsis arenosa on the cover. Hope that you find it interesting! doi.org/10.1016/j.tree.2023.11.007

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Adrián Gonzalo @adriangonzalo.bsky.social · 01/07/2025

Check out the Views & News piece that Joiselle Fernandes and I wrote for @nature.com on the recent work from @amarques.bsky.social and colleagues about one of the most bizarre ways to do meiosis rdcu.be/euabu. Explained for non-experts!

Diagram of two types of reproduction based on their meiosis. A. shows typical meiosis taking place in individuals with two copies of each chromosome (diploids) resulting in both male and female gametes carrying one copy of each chromosome. Fertilization restores the double copy for each chromosome. B. shows Canina meiosis in individuals carrying five copies of each chromosome (pentaploids) where male gametes only carry one copy of each chromosome and female gametes carry four copies of each chromosome. Fertilization restores the five copy for each chromosome.

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Adrián Gonzalo @adriangonzalo.bsky.social · 09/05/2025

Our latest work is out in @pnas.org! We have quantified and modeled the dynamics of early meiosis events, which can get really messy in polyploids (doubled number of chromosomes, double the trouble), but can also get fixed through adaptive evolution 🧵1/8. www.pnas.org/doi/10.1073/...

pnas.org

Improved synapsis dynamics accompany meiotic stability in Arabidopsis arenosa autotetraploids | PNAS

During meiosis, the correct pairing, synapsis, and recombination of homologous chromosome pairs is critical for fertility of sexual eukaryotes. The...

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Adrián Gonzalo @adriangonzalo.bsky.social · 23/04/2025

A beautiful reminder that the classification of allo- and autopolyploid is indeed more complex than whether they have hybrid or non-hybrid origin. Also, a beautiful reminder of how genome doubling can be a driver of agronomy-relevant innovations. Great paper! www.nature.com/articles/s41...

nature.com

Rapid formation of stable autotetraploid rice from genome-doubled F1 hybrids of japonica–indica subspecies - Nature Plants

This study details a process of duplicated (homoeologous) chromosome ‘scrambling’ in newly formed rice polyploids, indicating the possibility of natural ‘allo-to-autopolyploid’ evolution, with implica...

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