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Chloe Girard, PhD

@chloegirard.bsky.social
1.4K followers 1.1K following 425 posts

Personally done with meiosis I. Professionally in love with it. Permanent researcher at I2BC 🇫🇷 Arabidopsis 🌱 Sordaria 🍄 Genetics/Genomics 🧬 Fixed and live imaging 🔬. #meiosis4ever her/she

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Reposted by Chloe Girard, PhD
Harmit Singh Malik @harmitmalik.bsky.social · 01/10/2026
Hello fly and chromosome people in Paris! I’m giving a seminar on Friday October 2nd, kindly hosted by Marie-Anne Felix at IBENS (salle Favard, IBENS 46 rue d'Ulm 75005 Paris) at noon. Come to hear the latest from the lab (although we’re evolutionary biologists so sometimes things move slowly) 🫠
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Chloe Girard, PhD @chloegirard.bsky.social · 08/09/2026
In Poznan for the Plant Meiosis Meeting! The question for @piotraz.bsky.social is : will there be Poznan croissants at the conference?!!!
Me in Poznan
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Chloe Girard, PhD @chloegirard.bsky.social · 02/09/2026
I support Wikipedia, where information is still human-created, fact-checked, and 100% free. Join me! donate.wikimedia.org
donate.wikimedia.org
Make your donation now - Wikimedia Foundation
Donate to the Wikimedia Foundation, the nonprofit that hosts Wikipedia and other crucial free knowledge projects. Each year, the generosity of the 2% of readers who donate allows us to expand the reac...
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Chloe Girard, PhD @chloegirard.bsky.social · 01/09/2026
Thank you @pierregrognet.bsky.social for my HDR defense poster!!!
Poster advertising for my HDR defense, with me as Buzz Lightyear, titled “to interference and beyond” ❤️
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Chloe Girard, PhD @chloegirard.bsky.social · 18/07/2026
I have the best husband on Earth. #Brooklyn99 It's official: I will be leading my own independent team at @i2bcparissaclay.bsky.social starting in the fall ! Website coming soon.
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Benoit Rosa @benoitrosa.bsky.social · 12/12/2025
Tiens donc, il y a 25 postes de DR2 de moins que l'an dernier. Y aurait-il un rapport avec les 25 CPJ ouvertes par le CNRS il y a 4 ans ?
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Gonéri Le Cozannet @goneri76.bsky.social · 20/06/2026
Dans le climat actuel, 1976 serait un été frais. Une clarification salutaire de France Télévisions sur la base de données analysées par Julien Cattiaux et Christophe Cassou du CNRS.
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Reposted by Chloe Girard, PhD
RIKEN Center for Biosystems Dynamics Research (BDR) @riken-bdr.bsky.social · 06/11/2025
Team led by Tomoya Kitajima designed protein-based artificial #kinetochores to act as decoys to reduce bipolar microtubule pulling forces on chromosomes in aged mouse #oocytes, preventing premature #ChromosomeSegregation during meiosis I & II. In @natcellbio.nature.com 👇 doi.org/10.1038/s415...
doi.org
Designing protein-based artificial kinetochores as decoys to prevent meiotic errors in oocytes - Nature Cell Biology
Zhou et al. design protein-based artificial kinetochore constructs as decoys to prevent premature chromosomal separation in aged oocytes. These constructs compete with chromosomal kinetochores, reduci...
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Reposted by Chloe Girard, PhD
Emanuel Maiberg @emanuelmaiberg.bsky.social · 17/10/2025
wikipedia's data shows that AI is siphoning traffic away from the site, which is a danger to its sustainability. ironically Wikipedia is more important than ever to users who want reliable information instead of slop, and to AI companies that need it for training data www.404media.co/wikipedia-sa...
404media.co
Wikipedia Says AI Is Causing a Dangerous Decline in Human Visitors
“With fewer visits to Wikipedia, fewer volunteers may grow and enrich the content, and fewer individual donors may support this work.”
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Reposted by Chloe Girard, PhD
Michael Habig @michaelhabig.bsky.social · 13/10/2025
Want to understand how entire fungal chromosomes can be horizontally transferred? Join us to unravel the mechanism/consequences of horizontal chromosome transfer in a fungal pathogen as part of an ERC-funded project. Postdoc/PhD positions available. fungal-evolutionary-genetics.de/open-positio...
fungal-evolutionary-genetics.de
Open Positions
ERC-funded project on the mechanism of horizontal transfer of entire fungal chromosomes PhD PostDoc
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Reposted by Chloe Girard, PhD
Stephen Turner @stephenturner.us · 10/10/2025
Lost Science is a new NYT series of accounts from scientists who have lost their jobs or funding. You can send your story to the Times here www.nytimes.com/2025/10/08/c...
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Chloe Girard, PhD @chloegirard.bsky.social · 10/10/2025
Beaucoup de mauvaises nouvelles, célébrons les bonnes ! Le programme EVARS en absolument génial ! Apprendre aux enfants le consentement ("est-ce que je peux te prendre dans mes bras pour te consoler?"), pour diminuer les risques d'abus d'enfants = impératif !! www.education.gouv.fr/sites/defaul...
education.gouv.fr
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Reposted by Chloe Girard, PhD
Carl Zimmer @carlzimmer.com · 09/10/2025
Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE
nyti.ms
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Chloe Girard, PhD @chloegirard.bsky.social · 06/10/2025
1st desk rejection ! I am very proud of this paper and will persist nevertheless, Wish me luck (and share the paper widely ! Yes, I am doing shameless self-promotion) ! 💪
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Reposted by Chloe Girard, PhD
Nature @nature.com · 30/09/2025
Nature research paper: Holliday junction–ZMM protein feedback enables meiotic crossover assurance go.nature.com/42JHXnV
go.nature.com
Holliday junction–ZMM protein feedback enables meiotic crossover assurance - Nature
Holliday junctions maintain chromosome synapsis to enable crossover assurance in budding yeast.
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Reposted by Chloe Girard, PhD
Marie Monniaux @mariemonniaux.bsky.social · 01/10/2025
Wow this is quite amazing - I know almost nothing on recombination, but always assumed that the more similar the sequences were, the more likely they would recombine, turns out it's the opposite!
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Chloe Girard, PhD @chloegirard.bsky.social · 01/10/2025
This is the work of a tremendous PhD student, Benoit Madec, who did everything in this study (genetics, molecular biology, all the bioinformatics analyses) He defended his PhD on Monday and is now Dr Madec! I am very proud of him and all the work he has accomplished!
Benoît during his PhD defense on Monday!
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Chloe Girard, PhD @chloegirard.bsky.social · 01/10/2025
🚨 First pre-print from my team !! TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !
The recombination frequency (cM/Mb) along chromosome 4 of A. thaliana (female meiosis). 

In full hybrids (grey), where polymorphism is distributed all along chromosomes, most crossovers occur in the regions surrounding the Centromere (Cen), and very few at chromosome ends (Tel: telomeres). 

In lines where polymorphism is restricted to chromosome ends (purple), the local recombination rate increases drastically, at the expense of the non-polymorphic regions (yellow).
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Chloe Girard, PhD @chloegirard.bsky.social · 19/09/2025
Paper submitted! Not rejected yet!! Celebration is required 🥳 Thread will come as soon as it appears on BioRxiv 🥂
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Chloe Girard, PhD @chloegirard.bsky.social · 10/07/2025
Congratulations @heidiserra.bsky.social for your @cnrs.fr Bronze Medal !!! www.insb.cnrs.fr/fr/personne/... So proud to have such a badass friend and colleague ! #meiosis4ever
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Reposted by Chloe Girard, PhD
Harmit Singh Malik @harmitmalik.bsky.social · 25/06/2025
One thing to emphasize strongly is that funding to science is like oxygen to the brain. Temporarily restricting oxygen flow for ten minutes (while you figure your shit out) is going to have the same outcome as shutting oxygen off permanently. We are close to the ten minute mark.
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Tania Louis @tanialouis.fr · 24/06/2025
Je reprends la métaphore de Robin Jamet : mobilisons-nous pour le Palais de la découverte et faisons-en le panda de la CSTI, l'espèce emblématique qui attire l'attention sur l'état d'un écosystème et amène à le préserver. 🐼
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Laura Eme @lauraeme.bsky.social · 22/06/2025
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes. 🔗: doi.org/10.1016/j.ce... #Genomics #Evolution #CellBiology #LECA
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Chloe Girard, PhD @chloegirard.bsky.social · 22/06/2025
We’re here for the EMBO meiosis 2025 in Engelberg! Very nice venue, thank you Kirsten Bomblies and Marinela Dukic for organizing!
The Kursaal hall in Engelberg where the EMBO Meiosis 2025 is held
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Reposted by Chloe Girard, PhD
Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · 16/06/2025
🧬🌽 Happy Transposon Day! 🌽🧬 Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025
Barbara McClintock portrait
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Reposted by Chloe Girard, PhD
Yann Duroc @durocyann.bsky.social · 12/06/2025
Rappel parce qu’apparemment c’est pas intégré par tout le monde : Les variétés issue de mutagenèse aléatoire sont bien des OGM (décision de la CJUE en 2018) mais elles sont exemptées de régulation. Ainsi elles sont exemptées de mesures de traçabilité et d’évaluation des risques !
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Chloe Girard, PhD @chloegirard.bsky.social · 10/06/2025
Look at that red nucleus stretching like CRAZY ! Who knew nuclei could do that ! DNA stretching, sure, but what about the nuclear membrane ?! (scale bar 10µm !) The longest measured nucleus reached 71µm !!
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Reposted by Chloe Girard, PhD
Paul Graf @paulginva.bsky.social · 03/06/2025
Man comes to the US from Lebanon. Starts out delivering pizzas, becomes a Nobel winning neuroscientist. Trump freezes his funding, he gets an email from China offering to move his lab “any city, any university I want" with guaranteed funding for 20 years. What are we doing?
Ardem Patapoutian's story is not just the American dream, it is the dream of American science.

He arrived in Los Angeles in 1986 at age 18 after fleeing war-torn Lebanon. He spent a year writing for an Armenian newspaper and delivering Domino's at night to become eligible for the University of California, where he earned his undergraduate degree and a postdoctoral fellowship in neuroscience.

He started a lab at Scripps Research in San Diego with a grant from the National Institutes of Health, discovered the way humans sense touch, and in 2021 won the Nobel Prize.

But with the Trump administration slashing spending on science, Dr. Patapoutian's federal grant to develop new approaches to treating pain has been frozen. In late February, he posted on Bluesky that such cuts would damage biomedical research and prompt an exodus of talent from the United States. Within hours, he had an email from China, offering to move his lab to "any city, any university I want," he said, with a guarantee of funding for the next 20 years.
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Reposted by Chloe Girard, PhD
Tressie McMillan Cottom @tressiemcphd.bsky.social · 03/06/2025
This is a rupture, there will be a before and an after. There is no reason to believe the after will resemble the before, at all. This is a demarcation in the lives of thousands of researchers and tens of thousands of educators.
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Reposted by Chloe Girard, PhD
Ian Henderson @hendersi.bsky.social · 30/05/2025
A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @camplantsci.bsky.social www.jobs.cam.ac.uk/job/51488/
jobs.cam.ac.uk
Research Assistant / Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant / Research Associate (Fixed Term) in the Department of Plant Sciences at the University of Cambridge.
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Chloe Girard, PhD @chloegirard.bsky.social · 01/06/2025
Les gnocchi rôtis de @owiowifouettemoi.bsky.social c’est l’invention géniale
Picture of said roasted gnocchi with red onions, cherry tomatoes, and pieces of lard
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Chloe Girard, PhD @chloegirard.bsky.social · 28/05/2025
What a joy it was! Thank you to @namekawasatoshi.bsky.social and @cohenlab.bsky.social for their HUGE help organizing this meeting !! The French crew will organize next year's meeting as well, but will hand over the reins to another #Meiosis4ever community for 2027 !
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Reposted by Chloe Girard, PhD
Carl T. Bergstrom @carlbergstrom.com · 26/05/2025
These are VERY rough estimates, but here's life expectancy after diagnosis of type-I diabetes over the past 150 years. It was Banting and Best's discovery of how to isolate insulin in 1921 — not some fucking cooking class — that gave people including my daughter a new lease on life.
Plot of life expectancy after Type 1 diabetes diagnosis, 1850-2025. 

After the discovery of insulin in 1921, life expectancies go gradually from zero to seventy years.
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Chloe Girard, PhD @chloegirard.bsky.social · 18/05/2025
Second Triathlon S done! Very happy about my time (2h05, 750m swim, 23km bike, 5km run).
Me in my trisuit on the beach, next to my son holding a banner that says “Allez Maman Chloé” (Go Mommy Chloe)
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Dave Herman @dherman.dev · 13/05/2025
too cynical?
A Venn diagram with three circles: one for LLMs, one for Regexps, and one for teenagers. The intersection for LLMs and teenagers contains the label “confidently wrong.” The intersection for LLMs and Regexps contains the label “seems to work”. The intersection for Regexps and teenagers contains the label “inscrutable language.” The intersection for all three contains the label “trouble with braces”.
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Quoi de neuf en Histoire ? @qdnehistoire.bsky.social · 12/05/2025
Nous recevrons prochainement John Tolan, investigateur principal du projet « Le Coran européen », pour parler des découvertes de cette recherche, au moment où une polémique désolante le vise, et à laquelle il répond longuement dans le texte ci-joint.
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Reposted by Chloe Girard, PhD
Calum H. G. Johnston @chgjohnston.bsky.social · 12/05/2025
Pleased to share a new preprint - a great collaboration with @jessicaandreani.bsky.social and the Guerois lab at I2BC, and the Radicella lab at the CEA. Using stuctural modelling, we reveal & validate a 3 protein complex involved in DNA import during transformation. www.biorxiv.org/content/10.1...
biorxiv.org
A tripartite protein complex promotes DNA transport during natural transformation in firmicutes.
Natural genetic transformation is a conserved mechanism of bacterial horizontal gene transfer, which is directed entirely by the recipient cell and facilitates the acquisition of new genetic traits su...
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Allan Barte @allanbarte.bsky.social · 10/05/2025
Défilé de néo-nazis à Paris : il me semble pouvoir recycler ce dessin de l'année dernière, tel quel... Source : www.lemonde.fr/societe/arti...
Titre : Sans provoquer d’émoi politique ou médiatique
des centaines de néo-nazis défilent, cagoulés, dans Paris


Alors qu'en arrière plan, défilent dans la rue des centaines de néo-nazis cagoulés, sans y prêter attention, deux personnes discutent au premier plan :
- Pfff ! Vous avez vu, à la télé, ces étudiants qui manifestent pour un cessez-le-feu à Gaza ?
- C’est inquiétant pour le pays. Ces gamins ont perdu toute boussole morale !
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MAYosis @mayosis.bsky.social · 05/05/2025
It's going to be MAYosis !!! Register : meiosis.cornell.edu/mayosis2025/... We have it all : meiotic drive, recombination, adaptation, pairing, segregation, interference, resection, crossover landscape, chromosome axis, synaptonemal complex, chromosome dynamics ! #Meiosis4ever
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Carl Zimmer @carlzimmer.com · 02/05/2025
Time to catch up on the past week’s news about science and medicine in the US. Whew. 1/10
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Chloe Girard, PhD @chloegirard.bsky.social · 30/04/2025
May is upon us!
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 27/04/2025
One of the best things about science is the ability to speculate, sometimes wildly. As long as you cite evidence and are ready to change your mind if disproved, go for it! 🧪
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David Monniaux @monniauxd.bsky.social · 26/04/2025
En grandes pompes c’est en chaussures de clown ?
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Randall Munroe @xkcd.com · 25/04/2025
PhD Timeline xkcd.com/3081
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Steffi (she/her) @sillysciencelady.bsky.social · 18/04/2025
In this review, I write about why it is important to study synaptonemal complex protein evolution and highlight this with a few key examples of conserved features and unique adaptations.
sciencedirect.com
From conservation to adaptation: understanding the synaptonemal complex’s evolutionary dynamics
The synaptonemal complex (SC) is structurally conserved across eukaryotes and is essential for a proper progression of meiosis. Despite this conservat…
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Laura Haynes👩‍🔬⚾️🐾💙 @drlaurahaynes.bsky.social · 16/04/2025
Love this!!! #StandWithHarvard #AcademicSky
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Shikhara Bhat @shikharabhat.bsky.social · 13/04/2025
Sounds super interesting!
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MIT Press @mitpress.bsky.social · 08/04/2025
We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.
thereader.mitpress.mit.edu
The Coming Out of a Transgender Scientist
"I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."
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Sara Carioscia @saracarioscia.bsky.social · 07/04/2025
My main PhD work is up! See thread below. I would love to discuss! www.medrxiv.org/content/10.1...
medrxiv.org
Common variation in meiosis genes shapes human recombination phenotypes and aneuploidy risk
The leading cause of human pregnancy loss is aneuploidy, often tracing to errors in chromosome segregation during female meiosis. While abnormal crossover recombination is known to confer risk for ane...
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Reposted by Chloe Girard, PhD
Randall Munroe @xkcd.com · 08/04/2025
Tariffs xkcd.com/3073
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