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Pascal MARTIN 👨‍🔬🧬💻

@pgpmartin.fr
1.8K followers 3.3K following 32 posts

Senior Research Specialist (IR) @inrae-bfp.bsky.social Gene Expression #genomics #transcription #chromatin #bioinformatics #rstats Now working on polyploid cells in tomato 🍅 Formerly on 🌱 (Arabidopsis), 🍄 (Penicillium) , 🪰 (Drosophila), and 🐀 (Mouse)

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Reposted by Pascal MARTIN 👨‍🔬🧬💻
INRAE UMR1332 BFP @inrae-bfp.bsky.social · 15/09/2026
📢🧑‍🎓 Master2 internship available! Want to help develop a cutting-edge genomic technique? 🧬 If you're looking to master a mix of genomics, protein purification, and advanced imaging protocols, look no further, we have the perfect project for you! Details below: 👇 filesender.renater.fr?s=download&t...
Master2 internship offer. Download it here: https://filesender.renater.fr/?s=download&token=df7cb8bb-3c5c-4106-bd68-ae9ff09bafec
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INRAE UMR1332 BFP @inrae-bfp.bsky.social · 19/06/2026
🔬🤩 A nice confocal #microscopy image by Lina Boutaleb today! Tomato meristem from MicroTom 🍅, analyzed to study heat stress impact on cell division and DNA replication. 🧬 stained with Hoechst (cyan), while EdU (magenta) incorporation quantifies newly synthesized DNA during cell cycle progression.
Confocal microscopy image of a tomato meristem stained with Hoechst and EdU. Image by Lina Boutaleb from the #FDFE team.
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Reposted by Pascal MARTIN 👨‍🔬🧬💻
INRAE UMR1332 BFP @inrae-bfp.bsky.social · 05/03/2026
🎉 Congratulations to Loé Malgouyre on successfully defending her CIFRE PhD on Feb 20th! 🔬Her research explored the effects of Leafamine®, an animal protein-derived biostimulant, on tomatoes under heat stress. Supported by BCF Life Sciences & #FDFE teams. Bravo, Loé! 👏👩‍🎓
Pictures from the PhD defense of Loé Malgouyre at INRAE Bordeaux. Top left pictures show Loé standing in front of her supervisor Michel Hernould and the jury members. Top right picture is a portrait of Loé Malgouyre smiling. Bottom picture is Loé presenting her last acknowledgement slide at the end of her presentation.
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INRAE UMR1332 BFP @inrae-bfp.bsky.social · 09/01/2026
Un poste de MCF des Universités en "Génétique quantitative appliquée aux espèces végétales" est ouvert au concours 2026 pour l'Université de Bordeaux. Projet de recherche axé sur "Déterminants génétiques de la résilience des céréales aux stress multiples". Laboratoire BFP - Département SE (UB)
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Aureliano Bombarely @bombarelya.bsky.social · 25/09/2025
Pascal Martin follows at the #SOLRUB2025 with a presentation about endopolyploidy in #tomato fruit development. Endoduplication increases transcription. Changes in the chromatin accessibility contribute to ploidy-specific gene expression changes.
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INRAE UMR1332 BFP @inrae-bfp.bsky.social · 24/09/2025
Several members of the #FDFE team participate in the #SolRub2025 meeting in Torino, Italy this week. 3 talks and 3 posters presented. Stimulating meeting gathering specialists of the Solanaceae and Rubiaceae communities.
7 members of the FDFE team stand in front of the posters at the SolRub 2025 meeting.
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Reposted by Pascal MARTIN 👨‍🔬🧬💻
GENOTOUL Génopole Toulouse @genotoul.bsky.social · 23/05/2025
#Formations #bioinfo & #biostat 2025 ! (certaines déjà complètes) R, Seurat, ggplot2, mixOmics, machine learning, ASTERICS, RNAseq... Modules IA pour la #génomique avec Python 🧬 ☑️ Attestation fournie ☑️ Déj’ & café inclus ☑️ À partir de 150€/jour (académiques) 🔗 Pré-inscriptions : bit.ly/3ZvwHKd
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INRAE UMR1332 BFP @inrae-bfp.bsky.social · 21/05/2025
Quelques 📸 des Journées Jeunes Chercheur·e·s du département BAP, à Bordeaux 14-16 mai Organisées par un comité local, elles ont permis de mettre en valeur les travaux scientifiques des doctorant·e·s et postdoc via des présentations orales, posters, échanges scientifiques et moments de convivialité 👏
the picture above is the group of researchers, PhD students and postdocs who organized the conference. They are in the room where the conference was held and in the background there is a slide with the conference title.
The bottom picture is a group picture of all the participants standing in front of the Institute for Grape and Wine Sciences.
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INRAE UMR1332 BFP @inrae-bfp.bsky.social · 15/05/2025
🤓🌱 Two of our excellent PhDs, Loé and Emilia, took part in the “Tête Chercheuse” day at a secondary school in Dordogne This event, organized by @univbordeaux.bsky.social and @capsciences.bsky.social , aims to promote the role of women in science and inspire the next generation of scientists. 👏👩‍🎓👩‍🔬
Top left picture: Emilia is pipeting something in a tube in front of 2 young students
Top right: Loé is standing in front of a young student looking into a microscope
Bottom: Group picture with the students
Pictures © Cap Sciences
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INRAE UMR1332 BFP @inrae-bfp.bsky.social · 12/05/2025
📸 Here is the new group pic from the #FDFE team! Taken during our team building day 2025 @capsciences.bsky.social A great day of warmth, sharing and good vibes 🍃🤝 It strengthened team spirit and helped colleagues, new and old, get to know each other better✨ #FDFE #INRAE #Bordeaux
Group picture of the FDFE team. All members are standing on a stairway to fit everyone. There are 32 team members on the picture.
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Reposted by Pascal MARTIN 👨‍🔬🧬💻
Heng Li @lh3lh3.bsky.social · 18/04/2025
Preprint on hifiasm Nanopore-only assembly. Led by Haoyu Cheng: www.biorxiv.org/content/10.1...
biorxiv.org
Efficient near telomere-to-telomere assembly of Nanopore Simplex reads
Telomere-to-telomere (T2T) assembly is the ultimate goal for de novo genome assembly. Existing algorithms capable of near T2T assembly all require Oxford Nanopore Technologies (ONT) ultra-long reads w...
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Matthias Benoit @mattbnt.bsky.social · 21/03/2025
This week we’ve had the pleasure to host @pgpmartin.fr @inrae-bfp.bsky.social to launch our pilot CUT&RUN experiment on Medicago nodules! 🌱 Thanks for sharing your expertise with us, Pascal 👨‍🔬 and thanks @tulip-gs-labex.bsky.social for funding 🙏
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Matthias Benoit @mattbnt.bsky.social · 05/03/2025
🚨New paper published in @nature.com! Using pan-genetics across the Solanum genus🍅🥔🍆we reveal why gene duplications🧬are major contingencies in crop engineering. My postdoc work in the Lippman lab @CSHL, collab. with @katiejenike.bsky.social @mikeschatz.bsky.social chatz.bsky.social and many others!
nature.com
Solanum pan-genetics reveals paralogues as contingencies in crop engineering - Nature
Gene duplication and subsequent paralogue diversification are major obstacles to genotype-to-phenotype predictability.
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INRAE UMR1332 BFP @inrae-bfp.bsky.social · 13/03/2025
📢 #ScienceJob TECHNICIEN-NE BIOLOGISTE EN PHENOTYPAGE 🍓🍅 Vous êtes intéressé-e par: ➡ les recherches qui ont du sens 🌍? ➡ la biologie des plantes ? ➡ le travail en serre (notations) et au labo (architecture, cytologie)? Candidatez avant le 20/03/25 ❗ Plus d'infos 👇 jobs.inrae.fr/concours/con...
plant de tomate à gauche et plant de fraise à droite
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BIC_Bordeaux @bic-bordeaux.bsky.social · 05/01/2025
Happy new year! Let's start 2025 with an #ImageOfTheMonth from N. Bollier @inrae-bfp.bsky.social. Scanning confocal 3D reconstruction of a tomato shoot apical meristem. The fixed meristem was cleared using clearsee and the cell walls are stained by calcofluor white.
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jbrowse.org @jbrowse.org · 30/01/2025
We are pleased to announce JBrowse v3.0.0! This is the latest semver bump to our JBrowse 2 product line For this release, we created new features for phased and polyploid VCFs. The new phased mode in particular can reveal interesting patterns of inheritance in trio VCFs jbrowse.org/jb2/blog/202...
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Kim-Anh Lê Cao @mixomics.org · 30/01/2025
🚀 Ready to dive into omics data integration?
Our mixOmics online course kicks off in ONE month! Perfect for beginners and those looking to deepen their skills. Bring your own data and learn hands-on on your own data! 👉 Register now: mixomics.org/2024/12/onli... 📅 Spots are limited -- don’t miss out!
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Viktoria Cologna @colognaviktoria.bsky.social · 20/01/2025
Our global study on the state of trust in scientists is now out in Nature Human Behaviour! 🥳 With a team of 241 researchers, we surveyed 71,922 people in 68 countries, providing the largest dataset on trust in scientists post-pandemic 👇🧵https://www.nature.com/articles/s41562-024-02090-5
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INRAE UMR1332 BFP @inrae-bfp.bsky.social · 17/01/2025
#ScienceNow We didn't have adapters to centrifuge the tubes containing our nuclei 🤔 But our colleague Mickaël Maucourt from the #BFP_META team designed these for us and printed them! 🤓 They work perfectly! 🎉 Thank you! 🙏 We will soon share the link to the design.
3D printed adapter to centrifuge 2mL tubes containing nuclei
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Institut Pasteur | 130 years of biomedical research @pasteur.fr · 16/01/2025
The Institut Pasteur has decided to leave X (formerly Twitter) to join BlueSky! 🦋 The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...
pasteur.fr
Institut Pasteur decides to leave X
The Institut Pasteur, a research organization which for more than 130 years has been committed to tackling infectious diseases, sharing knowledge and defending science, has decided to leave X because ...
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Reposted by Pascal MARTIN 👨‍🔬🧬💻
Kim-Anh Lê Cao @mixomics.org · 06/01/2025
📢 Registrations for our next online course are open 📢 mixomics.org/2024/12/onli... Great course for mixOmics beginners, those who want to depend their understanding of our omics data integration methods. BYO data to analyse. Register before 11th Feb! #omics #rstats #dataintegration
mixomics.org
[open] Self-paced online course Feb 24 – April 11, 2025 | mixOmics
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Sebastian Soyk @sebastiansoyk.bsky.social · 21/12/2024
Very happy to see this work out on bioRxiv: We applied a synthetic GRF-GIF chimera for tomato plant transformation and found that it reliably enhances regeneration, increases the number of transgenics and shortens the time for genome editing experiments in tomato. www.biorxiv.org/content/10.1...
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Dariia Mykhailyshyna @dariia.bsky.social · 22/12/2024
An upd report on our workshops for Ukraine series on #RStats, #Python & more. So far, we have raised >86k euro & the workshops have been attended by > 3900 ppl! 👇you can find more info on how you can help & a detailed report. All info on workshops: bit.ly/3wBeY4S 1/n
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Phil Delacote @phildelacote.bsky.social · 14/11/2024
Many new people leaving the other place and coming here. So here is a starter pack of colleagues working at @INRAE_france on Agriculture, Environment, Food, Forests issues, from various disciplines. Please let me know if you want to be added. go.bsky.app/CuM8ekE
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Ana Conesa @anaconesa.bsky.social · 10/12/2024
The @conesalab.bsky.social conesalab.org is seeking to join motivated Postdocs through the #JuanDeLaCierva from @ageinves.bsky.social tinyurl.com/32acz58 and #CIAPOS tinyurl.com/bmrex8cc Contact us ASPA if interested in long-read, single-cell or spatial transcriptomics and multi-omics.
conesalab.org
Genomics of Gene Expression
Join Our Lab The Genomics of Gene Expression is led by Dr. Ana Conesa from the Institute for Integrative Systems Biology (I2SysBio), Spanish National Research Council (CSIC). We are interested in…
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JOBIM 2025 @jobim2025.bsky.social · 29/11/2024
L'appel à proposition pour les mini #symposiums de #JOBIM2025 est lancé !! Un mini-symposium: ➡️ réunit des scientifiques autour d'une thématique spécialisée en #bioinformatique 🗣️ ➡️ dure 3 heures ⌚ ⌛Attention, vous avez jusqu'au Vendredi 17 Janvier 2025 à 18h pour nous envoyer vos propositions!
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Marc Somssich @somssich.bsky.social · 02/01/2024
I have written a couple of threads 🧵 on "classic" #PlantScience papers. I always tag them with #PlantScienceClassics , but will also compile them here in this thread: 👇
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Plant Systems Biology @psb-vib.bsky.social · 04/12/2024
We are delighted to bring #ICAR2025 to Gent in Belgium! Abstract submission OPEN! icar2025.com @aabiologists.bsky.social @moritznowack.bsky.social @hildenelissen.bsky.social @bertderybel.bsky.social @mehta-lab.com @kuleuvenuniversity.bsky.social @viblifesciences.bsky.social
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Craig Kaplan @triggerloop.bsky.social · 04/12/2024
Look at this crazy thing www.nature.com/articles/s41...
nature.com
Near-identical macromolecules spontaneously partition into concentric circles - Nature
A particular liquid–liquid phase separation at a solid–liquid interface led to the unexpected partitioning of highly similar polymeric molecules into concentric circles.
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Sharon Machlis @smachlis.bsky.social · 29/11/2024
The {ggsci} #RStats 📦 “offers a collection of ggplot2 color palettes inspired by scientific journals, data visualization libraries, science fiction movies, and TV shows.” By Nan Xiao. Use with: scale_color_palname() scale_fill_palname() nanx.me/ggsci/ #RStats #ggplot2 #ggplot
Image shows sample palettes for UChicago, Star Trek and Tron Legacy
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Vangeli Geshkovski @vgeshkovski.bsky.social · 24/11/2024
Check out our new protocol avaliable in Methods in Molecular Biology! We describe a straightforward mass-spec protocol for the analysis of histone PTMs and variants link.springer.com/protocol/10....
link.springer.com
Quantitative Profiling of Histone Variants and Posttranslational Modifications by Tandem Mass Spectrometry in Arabidopsis
Histone dynamics constitute an important layer of gene regulations associated with development and growth in multicellular eukaryotes. They also stand as key determinants of plant responses to environ...
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Mitch Guttman @mitchguttman.bsky.social · 27/11/2024
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. www.nature.com/articles/s41...
nature.com
ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics
ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...
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Julien Roux @julienroux.bsky.social · 26/11/2024
I created a starter pack including people working in #bioinformatics core facilities 🧬 🖥️ I am sure I missed a lot of relevant people, so if you'd like to be added or know people who should be in there, let me know! go.bsky.app/LfGCpSX
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Bluesky Starter Pack @blueskystarterpack.com · 25/11/2024
blueskystarterpack.com
blueskystarterpack.com
Bluesky Starter Packs
Discover and connect with amazing people on Bluesky. Create and share curated lists of accounts to follow.
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Jonathan Jacobs @bioinformer.bsky.social · 22/11/2024
@nanoporetech.com Nice you see you all finally jumped on board over here! 🙌 🧪🖥🧬
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JOBIM 2025 @jobim2025.bsky.social · 04/11/2024
Bonjour agent.e, 🕵️ Nous avons besoin de votre aide. Le site Web #JOBIM2025 a été mis en ligne. 🥳 ⏩ jobim2025.labri.fr Votre mission, si vous l'acceptez, est de mettre en favori ce site, ainsi que de le partager à un maximum de collègues. Alors, cap ou pas cap ? 🧢
jobim2025.labri.fr
Journées Ouvertes en Biologie, Informatique et Mathématiques - 2025
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January Weiner @january3.github.io · 21/11/2024
Today I learned that combining a density plot with a jitter / dot plot is called a "raincloud" plot. And also discovered the {ggrain} package. Very nice, I remember doing it almost by hand in base R. #rstats www.njudd.com/raincloud-gg...
An example of the raincloud using the iris data set
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Tyson Barrett @healthandstats.bsky.social · 21/11/2024
👀
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Steven Salzberg @stevensalzberg.bsky.social · 21/11/2024
Check out our new paper led by Hayden Ji, in PLoS Computational Biology, on a hundreds of new protein-coding exnos in the human genome: journals.plos.org/ploscompbiol...
journals.plos.org
Upstream open reading frames may contain hundreds of novel human exons
Author summary We analyzed over 2000 human sequences that have been proposed to represent novel protein-coding genes, and that reside just upstream of known genes. These “upstream ORFs” (uORFs) would ...
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Vienna BioCenter Scientific Training @vbcscitraining.bsky.social · 21/11/2024
The Vienna BioCenter Scientific training unit is now on #Bluesky and we will share news and vacancies from our PhD program, summer school and other interesting initiatives. @impvienna.bsky.social @maxperutzlabs.bsky.social @gmivienna.bsky.social @imbavienna.bsky.social @univie.ac.at
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Eileen Furlong @eileen-furlong.bsky.social · 18/11/2024
My first post on Blue Sky - moving over ! For all post-docs out there - fantastic opportunity @EMBL. Independent group leader position: Core funding, state-of-the-art core facilities, access to fantastic Ph.D. students, and of course amazing colleagues. Please apply www.embl.org/jobs/positio...
embl.org
EMBL Jobs
We offer a wide range of challenging scientific and non-scientific positions at all of our European locations and encourage applications from international candidates at all career levels.
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Carmelo Ferrai @carmeloferrai.bsky.social · 14/09/2024
EpiSci - Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription @ZhangLab_UT www.nature.com/articles/s41...
nature.com
Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription - Nature Communications
The C-terminal domain of the largest subunit of RNA polymerase II (CTD) is phosphorylated and recruits regulators of transcription. Here the authors show that phosphorylated CTD, upon specific binding...
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Adam Phillippy @aphillippy.bsky.social · 16/09/2024
"Epigenetic control and inheritance of rDNA arrays" New preprint from the T2T acrocentrics team! We find a tight link between methylation and transcription of the rDNAs, including the occasional silencing of entire arrays www.biorxiv.org/content/10.1...
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LRSV Toulouse @lrsv-toulouse.bsky.social · 20/11/2024
Hi everyone!! We are excited to be here as a community of scientists working on #plantscience ☘️🌱 and their associated microbes 🍄 ! Want to follow our institute members? Here is our starter pack (to be updated): go.bsky.app/9p1bZz2
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All-Ireland Chromatin Consortium @aicc-ireland.bsky.social · 19/11/2024
Nice to see all you chromatin & epigenetics aficionados here! As we build our network back up please repost details for our upcoming webinar this Friday! We are delighted to welcome Emma Farley for her webinar 'Dependency Grammar of Developmental Enhancers' on November 22nd. Registration below 👇
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Rebecca Berrens @rberrens.bsky.social · 19/11/2024
Please register for the course on Transposable elements in #genomics and #datascience. We will be sharing the magic of #nanopore long reads for #transposon expression #tesky
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Altmetric @altmetric.com · 18/11/2024
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics
docs.bsky.app
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
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Pascal MARTIN 👨‍🔬🧬💻 @pgpmartin.fr · 18/11/2024
OrthoDB and BUSCO update: annotation of orthologs with wider sampling of genomes. Nucleic Acid Res doi.org/10.1093/nar/...
doi.org
OrthoDB and BUSCO update: annotation of orthologs with wider sampling of genomes
Abstract. OrthoDB (https://www.orthodb.org) offers evolutionary and functional annotations of orthologous genes in the widest sampling of eukaryotes, proka
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🇲🇽 Leonardo Collado-Torres @lcolladotor.bsky.social · 15/11/2024
📹 "Live exploration of latest #RStats news on Bluesky" @libdrstats.bsky.social @bsky.app intro: starter packs (including @jeremy-data.bsky.social & @sherlockpholmes.bsky.social) & feeds (algorithms) + @hadleywickham.bsky.social's curated feed, @bioconductor.bsky.social news 👀 youtu.be/hclxkkp-V_I
youtu.be
[2024-11-15] RStats on Bluesky
YouTube video by Leonardo Collado Torres
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Shaun Mahony @shaunmahony.bsky.social · 14/11/2024
Dusting off this account since it seems like BlueSky is suddenly the place to be! Here's a couple of resources for anyone interested in gene regulation, chromatin, or genomics: First, a long list of relevant accounts: bsky.app/profile/shau... (will make some starter packs at some point)
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