iiinova — where your digital self keeps evolving

Aureliano Bombarely @bombarelya.bsky.social · 08/05/2026

Today we had a nice presentation by Isabel Monte @isabelmonte.bsky.social at IBMCP seminar. She presented about evolution of receptor kinase-mediated immune signaling in plants. SERKs regulate conserved processes in land plants. Their ECD diversified their role in reproduction but loopB in immunity.

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Aureliano Bombarely @bombarelya.bsky.social · 29/04/2026

We close the #JABI2026 with. A plenary presentation by Francisco J. Veredas which will talk about large language models (LLM) in #bioinformatics.

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Aureliano Bombarely @bombarelya.bsky.social · 29/04/2026

Alicia Paredes opens the last sesión at the #JABI2026 about the use of #AI and #data_science in bioinformatics and biomedicine. She presents about cardiac insufficiency phenotype identification using AI.

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Aureliano Bombarely @bombarelya.bsky.social · 29/04/2026

Martin Garrido-Rodríguez brings us a great presentation about #descriptive_multiomics and predictive #systems_biology in today’s plenary at #JABI2026.

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Aureliano Bombarely @bombarelya.bsky.social · 29/04/2026

Last day at the #JABI2026 starts with a presentation by Maria Angeles Vargas-Perez which will be presenting about the mitochondria variant analysis of cloned horses.

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Aureliano Bombarely @bombarelya.bsky.social · 28/04/2026

Maria Toro closes the second #JABI2026 day with a presentation about microbiomes, genomes and how the scientific data is integrated in a genomic health platform.

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Aureliano Bombarely @bombarelya.bsky.social · 28/04/2026

#JABI2026 Session 4 (microbial #bioinformatics) starts with a presentation by Ana Lasa about the analysis of the rhizosphere of the melojo oak.

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Aureliano Bombarely @bombarelya.bsky.social · 28/04/2026

We come back after the #JABI2026 coffee break with #bioinformatic platforms, resources, and outreach with a presentation by Rocio Bautista about the Picasso supercomputer.

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Aureliano Bombarely @bombarelya.bsky.social · 28/04/2026

Fatima Sanchez follows the clinical bioinformatics session at #JABI2026 with a plenary presentation about about #digitsl_twins applied to cardiovascular research.

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Aureliano Bombarely @bombarelya.bsky.social · 28/04/2026

After a wonderful first day, we come back to the #JABI2026 with the clinical #bioinformatics session opened by Ignacio Garach.

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Reposted by Aureliano Bombarely

Vittoria Brambilla @vittoriab.bsky.social · 27/04/2026

I have some news! Fabio Fornara and I published a book! We are very happy of it!

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Aureliano Bombarely @bombarelya.bsky.social · 27/04/2026

The IV Andalusian Bioinformatics Days (JABI2026) starts with the wonderful introduction by the coordinator Jose V. Die.

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Aureliano Bombarely @bombarelya.bsky.social · 18/11/2025

We have done our first @protocolsio.bsky.social. Are you interested about #genome_annotation quality evaluation? We have developed a tool called #GAQET2 (github.com/victorgcb198...) which runs several tools like #AGAT, #BUSCO, and many other tools. You can find it at www.protocols.io/view/structu...

github.com

GitHub - victorgcb1987/GAQET2

Contribute to victorgcb1987/GAQET2 development by creating an account on GitHub.

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Aureliano Bombarely @bombarelya.bsky.social · 13/11/2025

This week I have the wonderful opportunity to present our results for the @catbiogenoma.bsky.social at the @iec.cat in Barcelona with many students and colleagues that I appreciate and admire. For a #genobotanist like me always amazed me #biodiversity in all its forms. Thanks!!! 🌿🌾🍄‍🟫🐚🪸🐊🐟🦀🦑🦎🐍🦋🪱🦉

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Aureliano Bombarely @bombarelya.bsky.social · 06/11/2025

Day 2 on #BCBGENO2025 course has been focused on the genome assembly, from reads to the contigs. Algorithms, methodologies, programs, a little bit of history and many many exercises... up to 16 different ones exploring short, and specially long read assemblies, from #ONT to #PBHiFi.

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Aureliano Bombarely @bombarelya.bsky.social · 04/11/2025

A good HMW DNA extraction can safe you a lot of time during the genome assembly. @tank-silvia.bsky.social (from @irnasa.bsky.social) explained on the first day at #BCBGENO2025 course about #experimental_design, #HMW_DNA extractions, and #DNA_sequencing.

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Aureliano Bombarely @bombarelya.bsky.social · 04/11/2025

A Kmer profile can give you a lot of information for your genome before you perform the #genome_assembly. At the end of the first day at the #BCBGENO2025 course, I asked the student to interpret the following #Kmer_profiles for 8 different datasets. Would you be able to make sense of these profiles?

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Aureliano Bombarely @bombarelya.bsky.social · 29/10/2025

We close the #biodiversity25 conference with a keynote presentation by Ute Hentschel Humeida about the basis of #sponge #symbiosis. “Life has evolved in a sea of microbes”. Microbial diversity already existed before the diversification of Eukaryotes. Host-microbes symbiosis appeared early in time.

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Aureliano Bombarely @bombarelya.bsky.social · 29/10/2025

Sam Speak closes the session at the #biodiversity25 with a presentation about #tilapia and the gene positive #selection for saline environments. There are 70 tilapia species with variation in saline tolerance. They sequenced several genomes within this group finding twelve positive selected genes.

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Aureliano Bombarely @bombarelya.bsky.social · 29/10/2025

Beam Danneels continues at the #biodiversity25 with a presentation about resistant chemical pollutants and induced defenses in #marine_mammals (#chemical_defensome, Chad). Cetaceans lost 2 keys TF involved in the ChD. They have developed a different path. Comparative genomics gave us some insights.

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Aureliano Bombarely @bombarelya.bsky.social · 29/10/2025

Ashwini V. Mohan follows at the #biodiversity25 presenting about the #limbless Layard’s snake skink. Snakes and caecilians lost their limbs due variations in one gene, but limbless #lizards have multiple evolutionary paths. They sequenced the Nessia layardi genome (1.55Gb) native to SriLanka.

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Aureliano Bombarely @bombarelya.bsky.social · 29/10/2025

Amanda Gardiner follows at the #biodiversity25 with a presentation about #genetic_diversity in sharks, rays and other vertebrates. She analyzed ROH, homozygous regions in vertebrates genomes produced by the VGP. Critically endangered species have more frequently long ROH than other species.

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Aureliano Bombarely @bombarelya.bsky.social · 29/10/2025

Niklas Wahlberg opens last day session at the #biodiversity25 with a wonderful presentation about diversification in #Lepidoptera. More than 1000 Lepidoptera #genomes have been sequenced! Some families have more than 100 reference genomes. They have been able to learn many things from them.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Simona Buonanno closes the 2nd day session at #biodiversity25 presenting benthic genomes in #ascidians. Botryllus schlosseri is a #species_complex. They sequenced 9 ascidian species, including 2 clades of B. schlosseri. BUSCO was higher than 90% for all the genomes.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Elisa Ramos brings us a presentation about #gulls at the #biodiversity25. The large white-headed gulls lineage has one of the faster #radiation processes of the birds of the northern hemisphere. LarOmics project aims to elucidate the genetic base of the gull #evolution.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Callum Thomas follows in the afternoon session at #biodiversity25 talking about the development of a #black_soldier_fly #pangenome. They can be used to produce protein for animals feeding. They can be fed by food waste. They are building a pangenome with individuals from different populations.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Camilla Mazzoni follows at the #biodiversity25 with a presentation about #sloths. Analysis of these genomes revealed that sloths have the higher content of LTR/copia in mammals, some impacting metabolic mitochondrial genes. Genomic studies can help to implement more efficient conservation actions.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Claire Merot opens the afternoon session at the #biodiversity25 with a presentation about the structural genetic diversity across the tree of life. Structural variants (SVs) are in order de magnitude higher than SNPs. TEs accounts for many SVs. SVs are different across different lineages.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Eniko Kiss closes the symbiosis genomics session at the #biodiversity25 with a presentation about #convergent_evolution. Mycorrhiza symbiosis is a good example of convergent evolution. Gene family analysis failed to find gene gains rather than losses. PCOC & ESL-PSC methods were used to overcome it

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Merce Montoliu brings us a presentation about wonderful #lichens at the #biodiversity25. Lichens are associations between mycobionts (fungi), photobionts (green algae or cianobacteria) and microbiomes. 38 different lichens were sequenced in DToL & ASH. Results show complex multiorganismal scenarios

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Jose V. Lopez follows at the #biodiversity25 presenting about the giant barrel #sponge genome. We are facing massive extinction event in marine reefs so we need to study sponges before they disappear. Sponges have distinctive #symbiotic microbiomes providing important ecosystem services.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Amjad Khalaf follows the symbiosis genomics session at #biodiversity25 presenting about #microsporidia tetraploid genomes. Most of them are recent autotetraploids. An interesting model of reproduction is proposed with two different paths: sexual and asexual reproduction.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Symbiosis genomic session at #biodiversity25 begins with a presentation by Mike Sweet about the #coral genome project. The coral reef bleaching is growing at alarming rate reaching 84% this year. By 2030, they may disappear. Some tools have been developed to slow down the process and allow survival.

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Aureliano Bombarely @bombarelya.bsky.social · 28/10/2025

Second day at the #biodiversity25 starts either a presentation by Arnau Sebe-Pedros about #cell_types. Cell types are functional and evolutionary units of animal multicellularity. Biodiversity Cell Atlas aims to scale up the application of single cell method across the tree of life.

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Aureliano Bombarely @bombarelya.bsky.social · 27/10/2025

Kai Ye closes the first session at the #biodiversity25 presenting about genome architecture evolution derived from 1000 species HiC data analysis. They use zoom-out approach. Checkerboard score (structural complexity) correlates with species complexity.

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Aureliano Bombarely @bombarelya.bsky.social · 27/10/2025

Nomar Waminal brings us a plant-based presentation at #biodiversity25 talking about a #crocus pan-repeatome. Crocus has an ancestral WGD prediversification. Then specific lineages have another more recent WGD. Repeats facilitated descending dysploidy and genome size expansion.

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Aureliano Bombarely @bombarelya.bsky.social · 27/10/2025

Lewis Stevens continues at the #biodiversity presenting about the programmed DNA elimination (PDE) in #nematodes. It is mostly telo & centromere satellite DNA but five years ago they discovered unexpected PDE (only telomeres) in ascaridids. Sequencing more genome discovered more species with PDE.

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Aureliano Bombarely @bombarelya.bsky.social · 27/10/2025

Tomas Hron follows at #biodiversity25 with a presentation about #avian evolution and #dot_chromosomes. Ten years ago new “hidden avian” genes appeared like the chicken genome. They are mostly associated to micro and dot chromosomes. Dot chromosomes are repeated-rich and a high gene loss rate.

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Aureliano Bombarely @bombarelya.bsky.social · 27/10/2025

Aleksandra Bliznina follows at #biodiversity25 with a presentation about the #evolution of the chromosomes in dark-winged fungus gnats. Autosome and GRCs chromosomes vary across different species. 3 genomes wasn’t enough to elucidate de origins of these chromosomes, so they went for 20!

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Aureliano Bombarely @bombarelya.bsky.social · 27/10/2025

Aoife McLysaght opens the conference #biodiversity2025 with a presentation about #genome #rediploidization. Hox genes have been classical example of duplicated genes in animals. Plant species have multiple whole genome duplications (WGD). Speciation events close to WGD may look like independent WGDs

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Aureliano Bombarely @bombarelya.bsky.social · 27/10/2025

The “Understanding Life: using largescale biodiversity reference genomes” #biodiversity25 begins. Mark Baxter opens the conference with acknowledgments. Special event will be a quartet playing music inspired by biology.

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Aureliano Bombarely @bombarelya.bsky.social · 07/10/2025

Are you jumping into reference genomes? are you looking for a #genome_assembly, #annotation, #analysis online course? We may be able to help. We have a @bcbhubcsic.bsky.social & @csic.es 6ECTS microcredential for you. Pre-inscriptions open until Oct. 14th. conexion-bcb.csic.es/microcredenc...

conexion-bcb.csic.es

Microcredencial CSIC BioMomentum GENOP01 | Conexión BCB

Microcredencial CSIC – GENOP01

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Aureliano Bombarely @bombarelya.bsky.social · 26/09/2025

Roberto Bassi closes the #SOLRUB2025 with an online plenary presentation about nature-based engineering of plant #photosynthesis.

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Aureliano Bombarely @bombarelya.bsky.social · 26/09/2025

Austin Hart closes the last session at the #SOLRUB2025 conference with a presentation about #tomato volatiles. There are two main BCAA-derived #volatile pathways in tomato. GWAS on a tomato population revealed 113 QTLs associated to BCAA derived volatiles. They identified several candidate genes.

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Aureliano Bombarely @bombarelya.bsky.social · 26/09/2025

Laura Van der Jeucht follows at #SOLRUB2025 with a presentation about how far-red light increases sugar content in #tomatoes. Far-red light exposure changes the plant architecture. Photosynthesis is not affected but the plant increases CO2 consumption. Sugar source content is increased.

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Aureliano Bombarely @bombarelya.bsky.social · 26/09/2025

Satya Swathi Nadakuduti follows in the #SOLRUB2025 meeting presenting about a #Rubicaceae species, Mitragyna speciosa, capable of produce #alkaloids with potential pharmaceutical applications.

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Aureliano Bombarely @bombarelya.bsky.social · 26/09/2025

Last day at the #SOLRUB2026 starts with a presentation by Antonio Granell from @ibmcp.bsky.social who is presenting about “how biotechnology can help us to design #tomato metabolic profiles”.

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