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Paul Fiedler

@pfiedler.bsky.social
593 followers 1.5K following 11 posts

🧑‍🎓 Master Student Medical Neurosciences @Charité 🧠 mental health advocate interested in memory, sleep, cognition, neuron-glia, mental health, and scicomm 🌈

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Reposted by Paul Fiedler
Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 12/10/2026
IoPPN experts contribute to independent review into mental health conditions, ADHD and autism. The report calls for a shift in how support is provided towards a more flexible, needs-led and effective approach, available earlier www.kcl.ac.uk/news/kings-e...
kcl.ac.uk
King's experts contribute to independent review into mental health conditions, ADHD and autism | King's College London
Researchers and clinicians from King's College London, including the Institute of Psychiatry, Psychology & Neuroscience (IoPPN), have contributed to the Independent Review into prevalence and support ...
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Tyler Black, MD @tylerblack.bsky.social · 10/09/2026
=-=-=-=-=-=-= Major release! =--=--=--=--= pediatricsuicides.ca I have compiled the worlds largest database of pediatric suicide information, consisting of 137 countries, from 1952-2025. In total, 27.64 BILLION person-years of data are represented. /1
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Enny van Beest @ennyvb.bsky.social · 04/09/2026
Textbook: tracking position during navigation is primarily the job of the hippocampus. Recent findings suggest a more complicated story. Recording >20k neurons brainwide, we indeed find spatial representations in every region! With @kenneth-harris.bsky.social and @carandinilab.net
Brainwide representations of a virtual corridor
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SfN Journals @sfnjournals.bsky.social · 31/08/2026
New in #JNeurosci from Kosik-Rose et al: Breathing waveforms correspond to the shape of brain waves in a variety of brain areas to potentially influence processes that impact mental health. doi.org/10.1523/JNEUROSCI.0731-26.2…
Graphs show respiration and neural amplitude cycles with airflow and belt morphology and illustrations of respiratory and brain activity.
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Romy Lorenz @romy-lorenz.bsky.social · 21/08/2026
Please share widely! 🚀 I am recruiting a PhD student for an exciting cross-species collaborative project using layer fMRI to investigate how interoception shapes cognitive control - Application deadline is: 1.10.2026 - Start: Jan 2027 www.mpg.de/26934670/phd...
mpg.de
PhD Position (m/f/d) | Ultra-High-Field Layer fMRI of Cognitive Control and Interoception
PhD Position in Ultra-High-Field Layer fMRI of Cognitive Control and Interoception
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Julia Schaefer @julia-sc.bsky.social · 17/08/2026
Episodic memory forms through action: gaze shifts sequentially sample experience as it unfolds 👀🏞️ 🧠 But actions may also help organize how the brain reactivates episodic memories! 👀🧠💭 🏞️ Check out our new preprint 👇 doi.org/10.64898/202... 🎉 @tobiasstaudigl.bsky.social & Aditya Chowdhury 👇🧵
doi.org
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Marta Silva @martamasilva.bsky.social · 12/08/2026
Check out our new paper! 🧠 Me, @xiongbowu.bsky.social and @fuentemilla.bsky.social review how reactivation at the end of events support memory formation and propose it serves multiple functions from preventing interference to helping preserve temporal continuity! ✨ www.cell.com/trends/cogni...
cell.com
Neural reactivation supports memory formation when events end
Memory routinely transforms continuous experience into discrete episodes that support flexible retrieval. We propose that these structured representations are established via rapid neural reactivation...
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Nora Harhen @noraharhen.bsky.social · 11/08/2026
How do we make good decisions with little experience? Adults can rely on memories of past choices. In our new study in @pnas.org we show kids & teens do something similar–but what they remember turns out to be quite different! www.pnas.org/doi/10.1073/...
pnas.org
Developmental changes in memory structure and precision alter the use of retrieved episodes during decisions for reward | PNAS
Most widely studied option evaluation strategies rely on knowledge accumulated across repeated experiences. But how should options be evaluated in ...
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Kari Hoffman @karihoffman.bsky.social · 30/07/2026
📣New paper! How does the sleeping brain help us to integrate new experiences while managing memories from the past? For his PhD work, @sabbaspoor.bsky.social recorded hippocampal ensembles in freely moving monkeys and found something unexpected. 🧵1/n www.nature.com/articles/s41... 🧪🧠📈👩‍🔬#OpenAccess
nature.com
Experience reorganizes content-specific memory traces in macaques - Nature Neuroscience
In macaques, old memories, relative to new ones, are supported by more stable and interconnected cell assemblies. New-biased and old-biased assemblies reactivate during overnight sleep and can sometim...
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Alana Darcher @alanadarcher.bsky.social · 30/07/2026
🎉 *extremely* excited to share our human single neuron + movie dataset is out in #ScientificData! 📄 Human neuron activity during an 83-minute movie from 2,286 neurons and 29 patients 🔗https://www.nature.com/articles/s41597-026-07955-0 1st public dataset from @humansingleneuron.bsky.social!🧵
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Max Planck Institute of Biophysics @mpibp.bsky.social · 13/07/2026
How do 2 meters of DNA fit inside a nucleus you can barely see? 🧬 Our new study mapped individual nucleosomes inside human cells.
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Itai Yanai @itaiyanai.bsky.social · 24/06/2026
🔥 Published today, and just in time for summer conferences, here are your guidelines for presenting badly www.nature.com/articles/s41... rdcu.be/fqa92
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Emily M. Bender @emilymbender.bsky.social · 25/06/2026
Are you annoyed with the anthropomorphizing language being used in the "AI" discourse, but not sure how to talk about this stuff without it? @nannainie.bsky.social and I have got you covered: buttondown.com/maiht3k/arch...
buttondown.com
How to talk about
Emily M. Bender and Nanna Inie In our op-ed for Tech Policy Press ("We Need to Talk About How We Talk About 'AI'"), we made the case against the...
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Neuroskeptic @neuroskeptic.bsky.social · 15/06/2026
Is paid peer review a good idea? "Reviewers were paid £220 per manuscript only if they completed the review on time, and the review met editorial quality expectations." www.biorxiv.org/content/10.6...
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tal boger @talboger.bsky.social · 15/06/2026
Do we perceive animacy itself, beyond its lower-level visual correlates? In @elife.bsky.social, @chazfirestone.bsky.social and I leverage “visual anagrams” — images whose interpretations change with orientation — to suggest the answer is: yes! elifesciences.org/reviewed-pre...
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Eiko Fried @eikofried.bsky.social · 13/06/2026
APA no longer shows me the actual paper, authors, abstract etc when I click on a paper in a search engine. Everything gated now, including basic paper info. Screenshots: (1) search hit (2) resulting APA site. Tried for a few papers now. What on Earth.
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Scott Marek @smarek0502.bsky.social · 11/06/2026
What matters most for childhood brain organization? We analyzed 649 variables. The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers. Even brain-IQ associations were better explained by SES. In Science today: www.science.org/doi/10.1126/...
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Michael Okun @michael-okun.bsky.social · 10/06/2026
I’ve officially resigned as Associate Editor for Frontiers in Systems Neuroscience. It used to be a reputable journal, but became a case study in how forced automation destroys academic integrity. 👇
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Stephan Lewandowsky @lewan.uk · 04/06/2026
🧵 Thread: Does the internet threaten democracy? I argue that it does in my latest piece in Science: doi.org/10.1126/scie... Here's the short version. 1/9 1/10
doi.org
The architecture of the internet creates risks for democracy
Will democracy survive the internet? Do we need to choose between Facebook’s surveillance capitalism or democracy? Layered lines of evidence can inform questions like these. When considered together, the evidence gives rise to a concerning picture, as summarized in a recent report for the European Commission that I co-led.
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Carl T. Bergstrom @carlbergstrom.com · 03/06/2026
1. How common is LLM use in scientific publishing, and how does it vary across field, publisher, journal prestige, author demographics etc.? @kylesiler.bsky.social has new paper in PNAS that addresses this question on a massive scale: 7.3 million papers from Elsevier, PLOS, MDPI, and Frontiers.
pnas.org
The diffusion of large language models in published academic articles | PNAS
Large language models (LLMs) are rapidly changing academic research, raising questions of who is adopting these tools and under what conditions. Th...
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The Transmitter @thetransmitter.bsky.social · 01/06/2026
A hackathon reveals that disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data, write @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence www.thetransmitter.org/reproducibil...
thetransmitter.org
18 teams analyzed a neuro dataset and got different answers
Disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data.
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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 01/06/2026
How does your brain filter out the noise and focus enough to learn efficiently? In our newest preprint, we use intracranial recordings + computational modeling to explore how selective attention shapes learning and state representations in the human brain 🧠 www.biorxiv.org/content/10.6... 1/🧵
bioRxiv preprint titled 'Coordinated human prefrontal dynamics sustain task-state representations during learning'
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Sakshi Ghai @sakshighai.bsky.social · 27/05/2026
Honoured to share our new paper in @nature.com today. Across 12 countries in eastern and southern Africa and Southeast Asia, 1 in 6 internet-using children had experienced technology-facilitated child sexual exploitation and abuse. A thread 🧵
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Nicole Rust @nicolecrust.bsky.social · 18/05/2026
My new @thetransmitter.bsky.social piece. Does Claude AI have emotions? *No*. Does Claude have nontrivial emotion-equivalents? *Yes*. Like your "memory" vs your laptop's; similar but not the same. Here, I unpack why that's interesting. www.thetransmitter.org/emotion/what...
thetransmitter.org
What can AI teach us about ‘emotions’?
Exploring why Anthropic’s AI, Claude, displays something like emotion could ultimately help us better understand the function that emotions serve in humans.
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Sophia Snipes @snipeso.bsky.social · 26/06/2025
Iota oscillations made it past peer review! Welcome to the zoo of sleep oscillations 😊 journals.physiology.org/doi/full/10....
journals.physiology.org
Iota oscillations (25–35 Hz) during wake and REM sleep in children and young adults | Journal of Neurophysiology | American Physiological Society
High-frequency brain oscillations in humans are currently categorized into beta (13–30 Hz) and gamma (>30 Hz). Here, I introduce a new class of oscillations between 25 and 35 Hz, which I propose to call “iota.” Iota oscillations have low amplitudes but can still be measured with surface electroencephalography (EEG). Within an individual, iota activity has a narrow spectral bandwidth typically less than 3 Hz, thus distinguishing it from broadband beta and gamma. Iota oscillations occur in sustained bursts during both wakefulness and rapid eye movement (REM) sleep. They are only found in a subset of individuals, more in children than in adults. Overall, iota oscillations are challenging to detect but could serve as a marker of both brain development and states of vigilance. NEW & NOTEWORTHY Electrical brain waves are some of the only neuronal signals that can be measured noninvasively in humans. Until now, only six classes of waves have been identified. Here I introduce a new class, iota, specific to wakefulness and rapid eye movement (REM) sleep. This makes iota just the second class of brain wave known to characterize REM sleep (after theta), and opens up new opportunities to investigate this elusive state.
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Natalie Christie Peluso 🧠 @nataliepeluso.com · 30/05/2026
"Structure and metabolism should no longer sit in separate boxes. The brain’s wiring could also be part of its fuel strategy. Myelin may be more than insulation; it may also form part of the brain’s adaptive metabolic infrastructure." 🧠👇 #neuroskyence www.thetransmitter.org/metabolism/b...
thetransmitter.org
Beyond glucose: The brain may feed itself
Myelin may serve as an energy reserve for the brain, and neuroscientists are rethinking how the brain stores, shares and protects energy.
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Joel I Berger @joelberger.bsky.social · 27/05/2026
We have a new preprint, examining what happens at the single neuron level in humans while people emerge from anaesthesia. Link: www.biorxiv.org/content/10.6.... tldr: neurons in medial temporal lobe (and thalamus, albeit limited data) often show increases in activity way before overt responses 🧠🟦 🧠💻
biorxiv.org
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juliovillalon.bsky.social @juliovillalon.bsky.social · 28/05/2026
We present the LARGEST normative model of the brain’s white matter microstructure: 54,583 subjects, 4-91 yrs, 19 datasets. We derived lifespan centile curves for DTI FA, MD, RD, AD, detecting anomalies for dementia, and Mild Cognitive Impairment: doi.org/10.1038/s414... ⤵️
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Allegretti Lab @matteoall.bsky.social · 27/05/2026
We're happy to announce our new preprint! 🐸 easymode: general pretrained networks for cellular cryo-ET. Segment ~20 cellular features – ribosomes, microtubules, mitochondria, nuclei & more – with zero model training. 🔗 doi.org/10.64898/202... 🧵👇
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Philip Sulewski @psulewski.bsky.social · 26/05/2026
Now out in Nature Neuroscience: "Fixation duration on natural scenes is explained by memory encoding not processing demand". www.nature.com/articles/s41... Our eyes don't linger because recognition is hard; they linger to remember. Let me take you on a quick tour. 🧵
nature.com
Fixation duration on natural scenes is explained by memory encoding not processing demand - Nature Neuroscience
By combining magnetoencephalography and eye tracking, this study sheds light on why people fixate on some parts of natural scenes longer than others. Rather than visual complexity, fixation durations ...
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Anna Ciaunica PhD @annaciaunica.bsky.social · 25/05/2026
www.nature.com/articles/s42...
nature.com
The metabolic engine of cognition: microglia–neuron interactions in health, ageing and disease - Nature Metabolism
This Review highlights how metabolic interactions between microglia and neurons shape brain health, and how their disruption in ageing and disease contributes to cognitive decline.
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Karen Hao @karenhao.bsky.social · 20/05/2026
On the one-year anniversary of EMPIRE OF AI, I am so, so excited to announce The AI Resist List, a new project that documents examples of resistance to the AI empires around the world 😍 airesistlist.org
The gorgeous AI Resist List homepage
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Andrew Perfors @perfors.net · 11/01/2026
As a cognitive scientist, I'm embarrassed at how long it took me to realise that emotion matters a lot, not just for understanding humans, but for understanding any thinking agent. Why? Because emotion is an indicator of what that agent values, and values are essential to rationality. Examples:
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Mike Greicius @mikegreicius.bsky.social · 18/05/2026
🧪 #alzheimer #amyloid Amazing new paper from @sfackley.bsky.social that exposes the statistical alchemy Lilly applied to their donanemab data: jamanetwork.com/journals/jam... There is little to no correlation between amyoid removal and clinical outcomes with donanemab (or lecanemab).
jamanetwork.com
Methodological Considerations for Quantile Aggregation in Alzheimer Disease Trials
This study evaluates the quantile-aggregation method using both simulated data and publicly available Alzheimer disease randomized trial data.
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Nick Myers @nick-myers.bsky.social · 25/05/2026
New paper with @paulm-k.bsky.social and Mark Stokes on how we switch internal attention between working memory contents. Beta-band oscillations tracked the magnitude and success of these switches. www.jneurosci.org/content/46/1... #neuroskyence
jneurosci.org
Human Beta Oscillations Reflect Magnitude and Fidelity of Priority Shifts in Working Memory
Flexible prioritization in working memory (WM) is supported by neural oscillations in frontal and sensory brain areas, but the roles of different oscillations remain poorly understood. Recordings in h...
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Meike Ramon @meikeramon.bsky.social · 21/05/2026
Science Needs 3rd Spaces We envision scientific third spaces as “collaborative hubs where researchers, artists, engineers, and practitioners co-develop methods, share resources, and pursue projects driven by curiosity". authors.elsevier.com/sd/article/S...
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Hugo Spiers @hugospiers.bsky.social · 17/05/2026
Massive study in @nature.com, converges with our past study of 750,000 people (Sea hero quest) to show u-shape curves for the impact of sleep. We studied cognition, here its disease impact: Sleep chart of biological ageing clocks in middle and late life www.nature.com/articles/s41...
nature.com
Sleep chart of biological ageing clocks in middle and late life - Nature
A cross-organ, multi-omics U-shaped relationship between sleep duration and biological ageing clocks highlights the potential of sleep optimization to promote healthy ageing, lower disease risk and ex...
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Martin Hebart @martinhebart.bsky.social · 16/05/2026
Finally, today is the day: Josefine Zerbe will present and release our new multi-echo 7T fMRI dataset LAION-fMRI during #VSS2026, with >30 fMRI session per subject and unprecedented stimulus diversity. Come to Talk Room 1 (Scene perception) today at 5:15. Details will follow in a separate thread!
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Mark Riedl @markriedl.bsky.social · 14/05/2026
ArXiV has a new LLM policy (Screenshots with alt text so you don’t have to click through to the other place and see all the stupid responses)
Attention @arxiv authors: Our Code of Conduct states that by signing your name as an author of a paper, each author takes full responsibility for all its contents, irrespective of how the contents were generated. 1/If generative AI tools generate inappropriate language, plagiarized content, biased content, errors, mistakes, incorrect references, or misleading content, and that output is included in scientific works, it is the responsibility of the author(s). 2/

We have recently clarified our penalties for this. If a submission contains incontrovertible evidence that the authors did not check the results of LLM generation, this means we can't trust anything in the paper. 3/The penalty is a 1-year ban from arXiv followed by the requirement that subsequent arXiv submissions must first be accepted at a reputable peer-reviewed venue. 4/

Examples of incontrovertible evidence: hallucinated references, meta-comments from the LLM ("here is a 200 word summary; would you like me to make any changes?"; "the data in this table is illustrative, fill it in with the real numbers from your experiments") end/
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Ben Hayden @benhayden.bsky.social · 06/05/2026
New paper from the lab! "Plasticity and language in the anaesthetized human hippocampus" www.nature.com/articles/s41...
nature.com
Plasticity and language in the anaesthetized human hippocampus - Nature
In the hippocampus, complex processing of sensory stimuli occurs even in the unconscious state.
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Elliot H Smith, PhD @neurosmith.bsky.social · 06/05/2026
New preprint alert! This one led by @neurozarr.bsky.social. Veronica wanted to know how neural traveling waves change during general anesthesia, so we dug back into some of the Utah array data that my PhD advisor collected back in the mid aughts. 🧵 www.biorxiv.org/content/10.6...
biorxiv.org
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Matt Seybold @mattseybold.bsky.social · 10/05/2026
Retractions never get proportional attention. This one should.
arstechnica.com
Influential study touting ChatGPT in education retracted over red flags
The retracted study on ChatGPT in education was already cited hundreds of times.
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Tim Behrens @behrenstimb.bsky.social · 09/05/2026
This is the May cover of NN but it has already been debunked on biorxiv www.biorxiv.org/content/10.6... Such a clear statement about the ridiculous pace of publishing (not just NN).
biorxiv.org
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PessoaBrain @pessoabrain.bsky.social · 07/05/2026
𝗠𝗮𝗷𝗼𝗿 𝗱𝗲𝗽𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝘁𝗵𝗲 𝗹𝗲𝗻𝘀 𝗼𝗳 circuit 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 Finally research is considering the functional/ anatomical complexity of the brain. It's not about regions, but how circuits function dynamically. www.cell.com/neuron/abstr... #neuroskyence
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Stephen Turner @stephenturner.us · 03/05/2026
Free and open-source images, icons, and tools for creating scientific illustrations doi.org/10.59350/5zt... 🧪
doi.org
Free and open-source images, icons, and tools for creating scientific illustrations
Phylopic, NIH Bioart, Bioicons, Scidraw, Open Science Art, Health Icons, Servier Medical Art, Biodiversity Heritage Library, the Noun Project, Segment Anything, Excalidraw, draw.io, Biographics
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Daniel Lakens @lakens.bsky.social · 03/05/2026
New blog post: There are 13 ways to analyse a replication study, but only one of them is coherent. Where I explain (based on our own recent preprint) why the SCORE project was right to focus on "p < .05 + similar effect size" when reporting the results. daniellakens.blogspot.com/2026/05/ther...
daniellakens.blogspot.com
There are 13 ways to analyse a replication study, but only one of them is coherent.
Paul Simon’s says there are 50 ways to leave your lover, and a similar abundance characterizes the contemporary literature on how to analyse...
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Carl T. Bergstrom @carlbergstrom.com · 01/05/2026
This paper was retracted from the @nejm.org because the images of bronchial branching after smoke inhalation were obviously and transparently manipulated by generative AI. Look at the ruler. I don't even know what lesson to draw from this. www.nejm.org/doi/10.1056/...
Crazy ruler above brachial branching
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Daniel S. Kluger @danlikesbrains.bsky.social · 01/05/2026
Latest preprint from @bodybrainbehaviour.bsky.social by @teresaberther.bsky.social and @martinasaltafossi.bsky.social on cardio-respiratory modulation of arousal and excitability states in the human brain - overlap, distinctions, and implications for brain-body #neuroskyence. osf.io/preprints/ps...
Schematic figure on the principles of cardio-respiratory coupling to human brain activity.
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Jonathan Basile @jonothingeb.bsky.social · 29/04/2026
I wrote for @lareviewofbooks.bsky.social about Kathryn Paige Harden's new book, an attempt to popularize the eugenics of criminality. I read it as a gambit to build liberal support for the project animating far right politics today, inspired by Replacement theory.
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