iiinova — where your digital self keeps evolving

Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 29/09/2026

Thanks to @nicolecrust.bsky.social for visiting Sinai and giving such an incredible talk! Appreciate you highlighting all the great work going on across our teams here 🙌

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 22/09/2026

How does a signal that guides our choices shape what we remember? See our recent preprint for an examination of the relationship between reward learning and memory directly in the human brain. Congrats to first author, @qasimetal.bsky.social!

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 04/09/2026

📣 We're hiring! The Saez Lab at Mount Sinai is seeking a postdoctoral researcher with experience in intracranial recordings, electrophysiology, BCIs, mood disorders, and/or computational modeling, to explore the neural basis of human cognition. 🗓️ Apply by September 30, 2026. Please share widely!

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Reposted by Ignacio Saez, PhD

The Friedman Brain Institute @sinaibrain.bsky.social · 21/08/2026

DEADLINE | SEPTEMBER 1st! Senior #Postdocs in all fields of #Neuroscience are encouraged to apply for this INCREDIBLE OPPORTUNITY to present your research at #MSNseminars, visit @mountsinainyc.bsky.social & meet w faculty/trainees! APPLY NOW 👉 docs.google.com/forms/d/e/1F... or use QR code on flyer!

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 18/08/2026

Congrats to Saez Lab grad student @emanuelmcoleman.bsky.social for presenting our work at the #GRC-FrontalCortex & GRS! By examining intracranial recordings in the hippocampus & amygdala across longitudinal timescales, Manny is exploring electrophysiological markers of fluctuations in wellbeing 🧠

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 05/08/2026

Attending #CCN2026 in NYC? Be sure to visit Gelana Tostaeva's poster on Thursday! Gelana will be presenting our recent work exploring how the human hippocampus can track locations in abstract social space 🧠 Read her full abstract here: 2026.ccneuro.org/poster/?id=y...

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Reposted by Ignacio Saez, PhD

The Transmitter @thetransmitter.bsky.social · 23/07/2026

Beyond their ability to restore function, brain-computer interfaces provide a window into the neural signals that underlie decision-making, speech and other cognitive processes. #neuroskyence By @claudia-lopez.bsky.social, @rebeccasky.bsky.social www.thetransmitter.org/brain-comput...

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 23/07/2026

Future BCIs could provide treatment for widespread disorders like depression, anxiety, PTSD, and OCD. Thanks to @neurosciencenews.bsky.social for covering the key takeaways and open questions from my recent review on the emerging field of cognitive BCIs. neurosciencenews.com/bci-depressi...

neurosciencenews.com

How Closed-Loop BCIs Will Treat Depression, Anxiety, and PTSD - Neuroscience News

A new study outlines closed-loop cognitive BCIs for depression, PTSD, and OCD.

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 21/07/2026

What’s holding us back from developing a clinical BCI for mental health? My new review in @cp-trendscognsci.bsky.social outlines a roadmap to overcome the unique hurdles facing cognitive BCIs by integrating & expanding on existing neurotech methods. Read here: authors.elsevier.com/a/1nSLK4sIRv...

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 20/07/2026

Where does cognition end & communication begin? 🧠 By mapping multi-region brain activity, we can see the complex circuitry behind speech and the thoughts that precede it. The next milestone? BCIs that restore cognition itself. Full video here: www.thetransmitter.org/brain-comput...

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 15/07/2026

Thanks to @bipolardiscoveries.org for supporting our work on the circuit-level basis of bipolar disorder! By uniting neurosurgery, neuroscience, and psychiatry, our unique multidisciplinary team is unlocking vital new insights into how the human brain works. More to come soon!

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 10/07/2026

Thoughtful insights from Michael Mager of @precisionneuro.bsky.social on what finally made commercial neural interfaces viable, and the potential future impact of BCIs on mental health. Read the interview at Rebellion Research: www.rebellionresearch.com/precision-ne...

rebellionresearch.com

Precision Neuroscience Co-Founder & CEO Michael Mager Sits Down With Rebellion Research

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 09/06/2026

Our understanding of depression is incomplete, leaving millions without effective treatment. I joined @hmarusak.bsky.social on her BrainSTEM podcast to discuss how my lab maps the mechanisms underlying the disease to develop better therapies. Listen here ⬇️ open.spotify.com/episode/2nX3...

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 01/06/2026

How does your brain filter out the noise and focus enough to learn efficiently? In our newest preprint, we use intracranial recordings + computational modeling to explore how selective attention shapes learning and state representations in the human brain 🧠 www.biorxiv.org/content/10.6... 1/🧵

bioRxiv preprint titled 'Coordinated human prefrontal dynamics sustain task-state representations during learning'

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Protocol Labs @protocollabs.bsky.social · 12/05/2026

“What the technology allows us to do… is to decouple the invasiveness of the surgery from the total amount of information that you can exchange with the brain.” Full conversation with Ben Rapoport of @precisionneuro.bsky.social on the Juan Benet Podcast >>> bit.ly/49puuoC

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 22/05/2026

So happy to see @christinamaher.bsky.social recognized by the Icahn School of Medicine at Mount Sinai with the Award for Outstanding Research in Neuroscience AND the Hausfeld Award honoring an exceptional PhD student! 🎉 Read more about Christina’s journey & all the 2026 awardees: icahnhonors.com

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Reposted by Ignacio Saez, PhD

Neuroscience and Beyond @neuroandbeyond.bsky.social · 07/05/2026

How do scientists measure memory? Unlike mood, memory has objective “ground truth” - you either saw it before or you didn’t. Nicole Rust explains why that makes memory easier to study across species. linktr.ee/neuroscience... #Memory #Neuroscience

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 15/05/2026

Congratulations to the Icahn Mount Sinai Class of 2026! 🎓🥳 A special shout-out to Drs. Qi Xiu Fu and Christina Maher on their hooding. Watching Qi Xiu and Christina grow into exceptional researchers and mentors has been a joy.

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 04/05/2026

Excited to share new work now published in @cp-iscience.bsky.social Using single-neuron recordings in humans, we show that dopamine neurons encode reward expectations derived from past experience––giving us a new look into how reward learning unfolds in the human brain 🧵👇

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 28/04/2026

Excited to be attending #SOBP2026 with my incredible team of trainees. Join us on the poster floor to learn about our current projects!

Details of Saez lab posters at the SOBP 2026 Annual Meeting.
Wednesday: Maren Cukor - Characterizing Aperiodic Components and Beta Oscillations in the Basal Ganglia (E-Poster V9)
Thursday: Henry Asher - Decreased Frontal Theta Coherence as a Depression Marker in Patients With Comorbid Epilepsy (Poster T141)
Friday: Dr Qi XIu Fu - Dopamine and Serotonin Transients Predict Depressive Symptom Relief Following DBS of Human Subcallosal Cingulate Cortex (Poster F121)
Saturday: Emanuel Coleman - Chronic Intracranial Recordings Reveal Frequency-Specific Correlates of Quality of Life in Epilepsy (Poster S153)

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juanbenet @juanbenet.bsky.social · 08/04/2026

Excited to launch a new podcast on the future of neurotech, computing, intelligence, and more. First guest: @maxhodak.bsky.social founder & CEO of @science.xyz building PRIMA, a retinal prosthetic restoring meaningful vision for patients with AMD. www.youtube.com/watch?v=24CM...

youtube.com

Max Hodak — Restoring Sight, Growing Neurons on Silicon, and Expanding Human Intelligence

YouTube video by Juan Benet Podcast

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 07/04/2026

We are bridging the gap between real-time brain function and the molecular mechanisms that drive it. Molecular insights into neurotransmission offer a major step toward precision treatments for psychiatric and neurological conditions. www.nature.com/articles/s41...

Header image for Molecular Psychiatry article: A transcriptional program associated with neurotransmission in the living human brain

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 02/04/2026

Thanks to @onemindorg.bsky.social for consistently championing the importance of community. Whether in the lab or through the arts, the power of connection is vital to transforming mental health care.

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 24/03/2026

Grateful for the opportunity to start two new collaborations through the #FBIScholars awards. These projects use a cross-species approach to explore mechanisms underlying human brain states and cognition. Thank you to the Nash and Friedman families for empowering boundary pushing neuroscience! 🧠✨

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 16/03/2026

Massive congratulations to Dr. @christinamaher.bsky.social on a brilliant defense! 👏 Christina is a force of nature, and her work is incredibly exciting. It’s been a true joy to co-mentor her alongside @angelaradulescu.bsky.social. Stay tuned for Christina’s papers dropping soon! 🎓🚀

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 27/02/2026

Ethics isn't a "side-project," it's the foundation of responsible neurotech. Congratulations to Fundación Tatiana for hosting the inaugural CINET neurotech conference and facilitating these critical conversations. I’m proud to center these considerations in my work.

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 09/02/2026

💡The neural mechanisms behind "aha!" moments are revealed in @natcomms.nature.com. Bridging computational neuroscience and AI, this approach offers insights into learning in biological and artificial systems. Congrats to @biyuhe.bsky.social and team! Proud to be part of this work. Learn more 👇

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 03/02/2026

Thanks to Ladan Jiracek for having me on the Neural Implant Podcast! We discussed how clinical neuroscience is combining high-resolution brain recordings with sophisticated behavioral studies to provide a truly comprehensive characterization of the human brain. 🎧 Listen here: tinyurl.com/yx47525v

tinyurl.com

Neural Implant podcast - the people behind Brain-Machine Interface revolutions: Ignacio Sáez - Neurotechnology for Cognition: Recording and Modulating the Human Brain

In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with Dr. , , whose lab uses intracranial brain recordings to study the biology of human cognition. Ignacio shares how cu...

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Reposted by Ignacio Saez, PhD

Natalie Schaworonkow @nschawor.bsky.social · 19/12/2025

📆 updated for 2026! list of summer schools & short courses in the realm of (computational) neuroscience or data analysis of EEG / MEG / LFP: 🔗 docs.google.com/spreadsheets...

docs.google.com

various computational neuroscience / MEEG / LFP short courses and summer schools

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 18/12/2025

This conversation between @davideagleman.bsky.social & Sergey Stavisky––two influential voices in the field––is a great primer on where #BCI is headed and what breakthroughs can mean for patients. Well worth a listen for anyone following the future of Neurotech👇🏽 tinyurl.com/4nfr8e47

tinyurl.com

What happens when we marry brains to machines? with Sergey Stavisky

What is a brain-computer interface? How can a paralyzed person use her brain to control a robotic arm? How can someone who’s lost the gift of speech use brain signals to broadcast his voice a…

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 11/12/2025

Exciting to see this paper out! Data shows episodic memory is dependent on a small number of precisely timed, transient, internally-generated states. Understanding these precise spatial and temporal dynamics is key to developing accurate and effective memory enhancement strategies 🧠

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 02/12/2025

It's always rewarding to connect with trainees at events like #Sfn25 & #NER2025. In these conversations, more and more students are asking how to break into Neurotech—fortunately for them, the community is stepping up with great resources to help them navigate their paths 🧵1/4

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 10/11/2025

✨ Program Manager Job Alert ✨ Join our Mount Sinai team in NYC to steer a multi-institutional neuroscience initiative aimed at understanding Bipolar Disorder. If you’re passionate about science, data & impact we’d love to hear from you! Learn More & Apply 👇 careers.mountsinai.org/jobs/3032351...

careers.mountsinai.org

Research Project Manager I (Dr Saez's Lab) - Neurosciences in New York, NY | Mount Sinai Health Systems

Mount Sinai is hiring a Research Project Manager I (Dr Saez's Lab) - Neurosciences in New York, NY. Review all of the job details and apply today!

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 05/11/2025

What does "Human-centered neural engineering and AI" mean? It means prioritizing the patient across the entire pipeline: Discovery, Design, and Delivery of neuro-engineering treatments for psychiatric disorders. Join me to discuss at @embs.org #NER25 hosted by @onemindaccelerator.bsky.social

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BD² @bipolardiscoveries.org · 28/10/2025

We are proud to award $18M to four new Discovery Research teams exploring neuromodulation and brain circuits in #Bipolar 🧠📈 🔗bit.ly/48M1TKP 🎙️ Hear from Daniel Pham, PhD, and the teams about their innovative projects 👇

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 28/10/2025

How mood states shift in the brain remains one of psychiatry’s biggest mysteries. With generous support from @bipolardiscoveries.org, our @sinaibrain.bsky.social team will apply cutting-edge techniques to map these transitions—aiming to build the most precise understanding of bipolar disorder yet.

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 23/10/2025

Must-read #NYBCI25 coverage by @neurotechnology.substack.com in @forbes.com. My key takeaway on cognitive BCI: Our biggest limiting factor isn't tech—it's fundamental scientific understanding. We can’t advance the tech until we define the disorder. Basic research must lead the way!

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 16/10/2025

What does it take to move neuroengineering breakthroughs into real-world impact? Our workshop at @embs.org #NER25 hosted by @onemindaccelerator.bsky.social, will explore how research, startups, and investment can come together to advance mental health care. neuro.embs.org/2025/satellite-workshops/

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 09/10/2025

"It takes a village!" and I'm incredibly grateful to be a part of this one. It was inspiring to witness the growing community driving cutting-edge #BCI research from the bench to real life at #NYBCI25 Here’s to building the future of #neurotechnology, together. 🧠⚡

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 02/10/2025

Excited to be speaking at #NYBCI25 this weekend, alongside so many leaders in #Neurotech and #BCI. It’s rare to have such diverse perspectives in one place, and I’m looking forward to the dialogue that emerges from bringing them together to advance the field. www.nybci.com/event/2886b6...

nybci.com

2025 New York BCI Symposium

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 29/09/2025

I left the 2025 @onemindorg.bsky.social music festival feeling inspired by the advances in mental health research and awareness that, together, are cracking the future of care wide open. Proud to be part of this community alongside peers like @maryamshanechi.bsky.social & @claudialugo.bsky.social!

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The Friedman Brain Institute @sinaibrain.bsky.social · 16/09/2025

❤️Thank you to all of Mount Sinai’s past, present and future #PostdoctoralScholars whose hard work and dedication play a vital role in advancing biomedical research. Here, we celebrate the #SchillerLab’s Dr. @paruljain.bsky.social! #NPAW2025 Learn More about her work👉 www.teenmiso.org/post/intervi...

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 17/09/2025

Big congrats to @intlbrainlab.bsky.social on two groundbreaking new papers! Based on the most comprehensive map of mouse brain activity yet, their findings show how decision-making is both widely distributed and shaped by past experience. Read more: www.thetransmitter.org/decision-mak...

thetransmitter.org

Everything everywhere all at once: Decision-making signals engage entire brain

The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 02/09/2025

What I’m reading 👉📚 A powerful & personal piece by @jacobrobinson.bsky.social (CEO @motifneuro.bsky.social) on how brain-computer interfaces could transform mental health. Honest, bold & inspiring. I encourage folks to read & subscribe. brainjacob.substack.com #BCIs #BrainComputerInterface

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 19/08/2025

Data from participants with treatment-resistant depression is revolutionizing our understanding of network disorders 🧠💻 Listen to a great discussion between @crozell.bsky.social and @braininspired.bsky.social on the potential of neuromodulation as a treatment for psychiatric disorders! 🎙️

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Reposted by Ignacio Saez, PhD

The Friedman Brain Institute @sinaibrain.bsky.social · 13/08/2025

NOT TO MISS! On Sept 22, 2025, Dr. Peter Rudebeck & The Lipschultz Center for Cognitive Neuroscience invite cognitive neuroscientists to a free symposium showcasing cutting-edge research being conducted across NYC & the surrounding area. Learn More | RSVP friedmanbrain.icahn.mssm.edu/lipschultz-s...

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 06/08/2025

Need reality check on where brain-computer interface technology stands today? 🧠💻 This insightful conversation from @wired.com offers an accessible and grounded introduction to the field, covering what's possible now and some of the challenges that lie ahead.

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Reposted by Ignacio Saez, PhD

Nature Human Behaviour @nathumbehav.nature.com · 21/07/2025

This study establishes how aperiodic activity, a ubiquitous signal linked to neural noise, develops in localized brain regions and illuminates the development of prefrontal control during adolescence in the development of attention and memory.

nature.com

The development of aperiodic neural activity in the human brain - Nature Human Behaviour

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 21/07/2025

How is prefrontal neural activity refined as we age? Out today in @nathumbehav.nature.com‬! This study, from Elizabeth Johnson, uncovers how subtle changes in neural 'noise' impact our attention, memory, and cognition through development. Proud to have contributed! www.nature.com/articles/s41...

The development of aperiodic neural activity in the human brain header

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Ignacio Saez, PhD @ignaciosaezphd.bsky.social · 09/07/2025

As we step into summer, we’re taking a moment to reflect on an amazing past year and offer a warm welcome aboard to our new lab members, @emanuelmcoleman.bsky.social‬ and Henry Asher! We’re thrilled to have you join the Saez Lab team and look forward to an exciting year ahead.

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