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Smitha Maretvadakethope (she/her)

@mathsmaret.bsky.social
84 followers 123 following 7 posts

Mathematical biologist in systems biology, synthetic biology and fluid dynamics. Really just an all-around fan of dynamical systems and their biological applications. Postdoctoral Researcher at Imperial College London.

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Reposted by Smitha Maretvadakethope (she/her)
Ruben Perez-Carrasco @perez-carrasco.bsky.social · 09/09/2026
The new AC-DC paper is out! ⚡ One small gene circuit, more than 30 distinct dynamical behaviours. Showing how small regulatory networks can hide a surprising amount of dynamical complexity. www.cell.com/cell-systems...
cell.com
Let there be multifunctionality: Uncovering the dynamical zoo of the AC-DC genetic circuit
Small gene regulatory circuits can encode a surprising diversity of dynamical behaviors. A biophysical model of the AC-DC motif reveals over thirty distinct bifurcation structures and shows how molecu...
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Smitha Maretvadakethope (she/her) @mathsmaret.bsky.social · 10/09/2026
The AC-DC gene circuit paper is out! What can a three-gene circuit do? A lot more than you might think! In this paper, we explore the complexity of the AC-DC circuit and identify over 30 distinct dynamical behaviours! www.cell.com/cell-systems... @icvara.bsky.social @perez-carrasco.bsky.social
cell.com
Let there be multifunctionality: Uncovering the dynamical zoo of the AC-DC genetic circuit
Small gene regulatory circuits can encode a surprising diversity of dynamical behaviors. A biophysical model of the AC-DC motif reveals over thirty distinct bifurcation structures and shows how molecu...
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Smitha Maretvadakethope (she/her) @mathsmaret.bsky.social · 24/03/2026
Did you think that small gene regulatory networks are only capable of very simple dynamics? Guess again! Even very simple networks are capable of a rich dynamics. Check out our brand new review paper: www.sciencedirect.com/science/arti... @perez-carrasco.bsky.social
sciencedirect.com
Simple systems, complex dynamics: lessons from minimal gene regulatory networks
Small gene regulatory networks (GRNs) are well-established biological modules that underpin cellular decisions and dynamical function. Their theoretic…
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Smitha Maretvadakethope (she/her) @mathsmaret.bsky.social · 11/09/2025
This issue could not have been possible without all of the fantastic contributions of all authors and reviewers, and obviously @royalsociety.org #biophysics #FluidDynamics
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Smitha Maretvadakethope (she/her) @mathsmaret.bsky.social · 11/09/2025
Our special issue of Phil Trans Roy Soc A on "Biological Fluid Dynamics" Emerging Directions" is officially out now! Originating from discussions at one of our SIG meetings, this special issue has 16 research articles and reviews on all things bioactive! royalsocietypublishing.org/toc/rsta/202...
royalsocietypublishing.org
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences: Vol 383, No 2304
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Smitha Maretvadakethope (she/her) @mathsmaret.bsky.social · 02/07/2025
Thank you to the Warwick Medical School for hosting the "Bridging mechanics and genetics in early development" workshop. Thank you especially for selecting my talk on AC-DC circuits for the "Best Talk" runner up award! There were so many excellent talks and I am honoured to be selected as runner up
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Reposted by Smitha Maretvadakethope (she/her)
Ruben Perez-Carrasco @perez-carrasco.bsky.social · 05/03/2025
Another day, another funky gene regulatory network behaviour! In our latest paper, we show how the mushroom bifurcation can encode an ultra-long biochemical timer. Even more interestingly, extrinsic noise can be used to improve timing precision! 🤯 @mathsmaret.bsky.social @josepsardanyes.bsky.social
journals.aps.org
Local nearby bifurcations lead to synergies in critical slowing down: The case of mushroom bifurcations
The behavior of nonlinear systems near critical transitions has significant implications for stability, transients, and resilience in complex systems. Transient times, $\ensuremath{\tau}$, become extr...
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Reposted by Smitha Maretvadakethope (she/her)
Kirsty Wan @micromotility.bsky.social · 04/03/2025
Re-posts appreciated! We have an open PhD position w/ Prof Harold Auradou on #microswimmers/#protists in complex media! Students get to spend at least 12 months in Paris, and will receive their PhD from both Exeter and Paris-Saclay! Apply by 31st Mar. More details: adum.fr/as/ed/voirpr...
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Smitha Maretvadakethope (she/her) @mathsmaret.bsky.social · 03/03/2025
My first paper in systems biology is in PRE! We investigate how local nearby bifurcations lead to synergies in critical slowing down, specifically the case of mushroom bifurcations in gene regulatory networks! journals.aps.org/pre/abstract... @perez-carrasco.bsky.social @josepsardanyes.bsky.social
journals.aps.org
Local nearby bifurcations lead to synergies in critical slowing down: The case of mushroom bifurcations
The behavior of nonlinear systems near critical transitions has significant implications for stability, transients, and resilience in complex systems. Transient times, $\ensuremath{\tau}$, become extr...
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Smitha Maretvadakethope (she/her) @mathsmaret.bsky.social · 03/03/2025
Hello World! Happy to finally get around to joining Bluesky!
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