Sign in

Patrick Phillips

@patrickphillips.bsky.social
3.4K followers 609 following 177 posts

Geneticist at University of Oregon @uoregon. Worms, C. elegans, aging, evolution, genetics, genomics, complex traits. Former provost and interim president. Lab: pages.uoregon.edu/pphil GScholar: scholar.google.com/citations?user=J…

PostsRepliesMedia
Reposted by Patrick Phillips
Silas Tittes @silastittes.bsky.social · 21/09/2026
I’m excited for Jordan Rodriguez’s paper and software, This Must Be the Place and EcoLocator! She uses global prediction of location and climate of origin to identify loci with signatures of local adaptation. Also applies to Doug Fir data. Feedback welcome! www.biorxiv.org/content/10.6...
biorxiv.org
This must be the place: deep learning local adaptation
Climate change is increasingly disrupting the relationship between locally adapted populations and the environments in which they evolved, creating an urgent need for tools that connect genomic variat...
23618
Reposted by Patrick Phillips
allen institute @alleninstitute.org · 03/09/2026
What if the next breakthrough for human health, climate resilience, or clean energy isn’t waiting to be found in nature, but is waiting to be designed? Today, we’re launching AI BioDesign, a bold endeavor to explore the uncharted design space of life.
162
Patrick Phillips @patrickphillips.bsky.social · 20/07/2026
A watched H-index never increases.
020
Patrick Phillips @patrickphillips.bsky.social · 09/07/2026
Terrific article on former postdoc @amywebster.bsky.social new NSF Career award at Florida State. Great things coming! news.fsu.edu/news/univers...
news.fsu.edu
FSU biologist earns $1 million NSF CAREER Award for epigenetics research
A Florida State University geneticist has earned one of the most prestigious awards available to early career faculty for her work investigating how
2151
Patrick Phillips @patrickphillips.bsky.social · 04/07/2026
I’ve been posting about the University of Oregon’s budget issues on LinkedIn. Here is my latest, with links to the other two articles. www.linkedin.com/posts/patric...
linkedin.com
University Budget Crisis 2: Questions answered, questions raised | Patrick Phillips
I have written a couple of articles about the looming financial crisis at the University of Oregon, as well as steps that we took to try to prepare of this when I was in the administration. These art...
020
Patrick Phillips @patrickphillips.bsky.social · 02/07/2026
I've been using Anthropic's Operon, which is now Claude Science, for a few hairy projects lately. The amount of problem solving it has to do just to get packages installed properly is pretty insane, but matches our general experience. Worth doing just on that basis alone.
210
Patrick Phillips @patrickphillips.bsky.social · 01/07/2026
This is a very odd paper for Am Nat to publish. Wow, use engineered genotypes to study selection, who would have thought of such a thing (citations?). They don't even talk about potential issues/restrictions of releasing engineered animals into the world. www.journals.uchicago.edu/doi/epdf/10....
journals.uchicago.edu
Harnessing gene knockouts to study selection and aid conservation
010
Patrick Phillips @patrickphillips.bsky.social · 29/06/2026
Asked Claude to proofread a commentary I'm drafting. For one sentence, it replied "no typo, intentional dry humor." Oh it knows me well already.
020
Reposted by Patrick Phillips
The Royal Society @royalsociety.org · 05/06/2026
Professor Joe Felsenstein FRS is elected a Fellow of the Royal Society. After initially working on population genetics theory of recombination, of migration, and of speciation, his main focus has been on phylogenetic inference. #RSFellows royalsociety.org/people/joseph-fels…
115640
Reposted by Patrick Phillips
bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 29/04/2026
The genome of the Pacific acorn barnacle provides insights into the evolution of extremely large populations www.biorxiv.org/content/10.64898/20…
077
Reposted by Patrick Phillips
callista yee @csybio.bsky.social · 07/04/2026
It is with great sadness that I'm sharing the news that Dr. Don Moerman passed away this weekend. He was such a legend in the #Celegans and Canadian science community.
9329
Patrick Phillips @patrickphillips.bsky.social · 04/04/2026
Great to see some of our constructs highlighted in this super helpful review.
050
Reposted by Patrick Phillips
Karen Benjamin Guzzo @karenguzzo.bsky.social · 21/03/2026
In 2024, NIH published 756 funding announcements (NOFOs) In 2025, it published 120. In 2026, as of 3/15, it published 14. Scientific program staff can no longer steward their fields b/c every NOFO must be approved by political appointees in the NIH director’s office, the DHHS, & the OMB.
elizabethginexi.substack.com
I Wrote Research Funding Announcements for NIH for 22 Years. This Year They’ve Published 14
How NIH went from 756 funding announcements to 14 in two years — and what it means for every disease that depends on federal research
02822
Reposted by Patrick Phillips
Scott McGrath @smcgrath.phd · 20/03/2026
The research center of gravity is shifting faster than many expected. New data suggests China's public R&D spending could overtake the US by 2028. While our investment grew 12% since 2013, theirs surged 90%.
nature.com
China could be the world’s biggest public funder of science within two years
Forecast by science-policy researchers raises questions about where the epicentre of global research will shift to in the coming decade.
66131
Reposted by Patrick Phillips
Drug Monkey @drugmonkey.bsky.social · 18/03/2026
13% success rates for FY2025 grant awards. NIH finally releases some FY2025 success rate data drugmonkey.wordpress.com/2026/03/18/n...
drugmonkey.wordpress.com
NIH finally releases some FY2025 success rate data
In a new post tagged NIH Funding Blog, we see the first report on success rates, which for some reason has been absent from the Data Book up until now*, even as other FY2025 statistics have been in…
43623
Reposted by Patrick Phillips
Jeremy Berg @jeremymberg.bsky.social · 13/03/2026
12/25
A line graph showing the fraction of R01 applications funded as a function of percentile for NIA. The estimated success rate for FY2024 was 15.8% compared with 5.8% for FY2025.
3139
Reposted by Patrick Phillips
Jeremy Berg @jeremymberg.bsky.social · 13/03/2026
Following @joshuasweitz.bsky.social post and discussions with him and the Vox story, I have estimated R01 success rates for each NIH institute and center with enough awards for this to be meaningful. A long 🧵... 1/25
49962
Reposted by Patrick Phillips
Prasad Jallepalli, MD, PhD @prasad.bsky.social · 13/03/2026
we are losing so much talent, progress, and hope for no good reason www.vox.com/future-perfe...
321274600
Reposted by Patrick Phillips
Justin Blumenstiel @bdelloid.bsky.social · 11/03/2026
There is a nice discussion about this book in this interview with Felsenstein as part of the "Reflections on Modeling and Theory in Population Biology" series, presented by the Society for Modeling and Theory in Population Biology. Discussion starts at 48 minutes: www.youtube.com/watch?v=ZSSx...
youtube.com
Reflections on Modeling and Theory in Population Biology: Joe Felsenstein
YouTube video by SMTPB
042
Patrick Phillips @patrickphillips.bsky.social · 11/03/2026
Perhaps the most unusual book in my library. Could also be used as a useful tool to bonk young whippersnappers on the head when they don’t realize how great they have it (the thing is massive).
2102
Reposted by Patrick Phillips
Angel G. Rivera-Colón @arcolon14.bsky.social · 05/03/2026
Check our new preprint from the KR-colab with @ramencult.bsky.social and Andy Kern: MKado: a toolkit for McDonald-Kreitman tests of natural selection doi.org/10.64898/202...
doi.org
194
Reposted by Patrick Phillips
Javier Apfeld @javierapfeld.bsky.social · 24/02/2026
Encoding recent movement history with Wormtrails makes spatial differences in C. elegans behavior much easier to see. In this assay, worms not only avoid the hydrogen peroxide gradient on the left, but also move faster near it. 4/
132
Patrick Phillips @patrickphillips.bsky.social · 17/02/2026
Out in print in Geroscience by @rosealsaadi.bsky.social: Pro‑longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan. Most interventions that help hermaphrodites also improve male lifespan, not necessarily reproductive heathspan. link.springer.com/epdf/10.1007...
0137
Reposted by Patrick Phillips
Drug Monkey @drugmonkey.bsky.social · 10/02/2026
taps microphone...
093
Reposted by Patrick Phillips
Javier Apfeld @javierapfeld.bsky.social · 28/01/2026
Friends! I am so happy to share our new preprint! Hydrogen peroxide has been the most common reactive chemical threat to life forms since the Great Oxygenation Event 2.5 billion years ago. How do animals like C. elegans sense it fast and escape? www.biorxiv.org/content/10.6... Thread 1/
78631
Reposted by Patrick Phillips
Saloni @scientificdiscovery.dev · 07/01/2026
The resolution of microscopes has increased over 10,000 fold over the last 200 years. It's allowed scientists to examine not only cells, but bacteria, then viruses, their protein structure, and, eventually, the individual atoms that comprise them.
showing how microscope resolution has improved more than 10,000× over the past 200 years. The horizontal axis shows year (1800s to 2025). The left vertical axis shows feature size, from 1 micrometer (small bacteria) down to 0.01 nanometers (atomic nuclear structure). The right vertical axis shows resolving power in inverse angstroms. A blue curve at the bottom represents light microscopy, limited by visible-light diffraction to about 200 nanometers. A tan curve rising sharply in the mid-20th century represents electron microscopy, reaching nanometer-scale resolution. A red region near 0.1 nanometers shows aberration-corrected electron microscopy surpassing the electron diffraction limit. A blue region at the top shows ptychography achieving the highest resolving power through overlapping diffraction patterns and computation. Dots label key scientists and institutions at milestones. Overall trend shows steady, then dramatic gains in resolution over time.
412635
Reposted by Patrick Phillips
Peter Sarkies @psarkies.bsky.social · 06/01/2026
Need a bit of escapism? Not exactly Lord of the Rings, but in similar vein: doi.org/10.1038/s443...
link.springer.com
Epimutations: raw material for evolution? - The EMBO Journal
Epigenetics is fundamental to cell differentiation as it enables cells with identical genomes to adopt distinct fates. Some epigenetic information can also be transmitted between generations, in a pro...
23821
Patrick Phillips @patrickphillips.bsky.social · 25/12/2025
Not totally sure why my son wanted a thermal camera for Christmas, but we’re now prepared to drop our first techno demo track.
0100
Reposted by Patrick Phillips
Gavin Woodruff @weirdworms.bsky.social · 19/12/2025
Very excited to share this work led by Austin Link, a graduate student in our lab. We have discovered a novel, fig-associated microbe that promotes reproductive success via variable life history mechanisms in two nematode species. www.biorxiv.org/content/10.6...
biorxiv.org
A novel, fig-associated microbe promotes reproductive success via variable life history mechanisms in C. elegans and C. inopinata
Variation in life history strategies is among the most striking features of animal diversity. Simultaneously, the microbes an animal interacts with are a critical and dynamic aspect of the host enviro...
1145
Patrick Phillips @patrickphillips.bsky.social · 11/12/2025
Watch this if you haven't. Pro science viral marketing at its best — and 100% authentic to Tim Boyle's sense of humor and plain spoken approach to the rational. Proud of homegrown @columbiasportswear.bsky.social for the approach. www.youtube.com/watch?v=JxJO...
youtube.com
Expedition Impossible | Columbia Sportswear
YouTube video by Columbia Sportswear
050
Reposted by Patrick Phillips
EvolDir @evoldir.bsky.social · 10/12/2025
The Gibson lab at UVA is hiring a postdoc to study dispersal as a parasite avoidance mechanism. Apply by mid-January: uva.wd1.myworkdayjobs.com/UVAJobs/j…. #postdoc
uva.wd1.myworkdayjobs.com
Research Associate in Biology
The Department of Biology at the University of Virginia invites applicants for a post-doctoral Research Associate position in the lab of Professor Amanda Gibson as part of an NSF-funded project. The Gibson lab is broadly interested in the evolution of avoidance versus resistance as modes of parasite defense. This project specifically tests the idea that host dispersal evolves as an escape in space from parasites, and it evaluates the downstream consequences of dispersal for the evolution of host resistance. The work makes use of the experimental tools and resources available for the model nematode C. elegans and its natural parasites. Associated projects entail evolve-and-resequencing, quantitative trait mapping, and field sampling with spatial analyses. The selected candidate will also mentor undergraduate students in independent research projects through a summer program for incoming transfer students. Find out more about the lab at https://coevolving.org. REQUIRED QUALIFICATIONS: o A PhD in Biology or a related field by the start date. PREFERRED QUALIFICATIONS: Demonstrated conceptual and technical strengths in host-parasite interactions, evolutionary ecology, evolutionary genetics, and/or dispersal biology Experience in basic lab and molecular work A strong background in experimental design, data analysis, and data management Excellent written and oral communication, demonstrated by a strong publication record, consistent with the candidate’s career stage, and presentations at conferences Demonstrated ambition, creativity, independence, and ability to work well with others Experience in and dedication to mentoring junior trainees APPLICATION PROCEDURE: Apply online https://jobs.virginia.edu/us and search for R0078709. Attach a cover letter outlining your qualifications and motivation for pursuing the position, curriculum vitae, and contact information for three individuals who can provide professional reference letters. In the cover letter, please address your fit with the qualifications above and your experience in mentoring undergraduates. Please note that multiple documents can be uploaded in the box. APPLICATION DEADLINE: Review of applications will begin on January 15, 2026. The University will perform background checks on all new hires prior to employment. Anticipated start date for this position is May, 2026, but the start date is flexible. This is a one-year appointment; however, appointment may be renewed for additional two, one-year increments, contingent upon available funding and satisfactory performance. For questions about the position, please contact Amanda Gibson, Associate Professor, at akg5nq@virginia.edu. For questions about the application process, please contact Richard Haverstrom, Academic Recruiter, at rkh6j@virginia.edu. For information on the benefits available to postdoctoral associates at UVA, visit postdoc.virginia.edu and hr.virginia.edu/benefits. The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Click here to read more about UVA’s commitment to non-discrimination and equal opportunity employment. PLEASE READ: The job postings for this page have been moved to a new location. Please visit the UVA Careers Websites to navigate to the appropriate site, or click UVA Careers in the upper right corner of this page to view open positions. If have already applied and need to log in to your existing Workday account, please click Sign In in the upper right corner of this page. Please do not sign in until you have visited and applied through a UVA Careers website.
0610
Patrick Phillips @patrickphillips.bsky.social · 28/11/2025
Inconceivable!
040
Patrick Phillips @patrickphillips.bsky.social · 26/11/2025
Natsume Söseki (1987): The artist can be defined as one who works within the four corners of the world to suppress what is called common sense and no longer inhabits more than three of them. 1/3
100
Patrick Phillips @patrickphillips.bsky.social · 16/11/2025
I’ve definitely seen lines at our famous campus Prince Puckler’s Ice Cream, but never a happy mob. That’s apparently what a perfect fall Saturday in Eugene following a Friday night football win brings.
130
Reposted by Patrick Phillips
Matt Barber @biobarber.bsky.social · 15/11/2025
Going to break my social media hiatus for a belated congratulations to @kdc509.bsky.social on an outstanding thesis defense last week! I cannot say enough good things about Killian - an amazing scientist and human being.
Killian standing in front of a podium at his thesis defense!
2302
Reposted by Patrick Phillips
Maureen Barr @barrlab.bsky.social · 07/11/2025
DAF-2/IGF-1 degradation: Males WAY outlive hermaphrodites! This is so cool. @patrickphillips.bsky.social
Fig. 1 Ubiquitous and tissue-specific DAF-2 degradation extends male lifespan. (a) Kaplan-
Meier curves showing survival of C. elegans hermaphrodites and males following ubiquitous
DAF-2 degradation. Purple lines denote hermaphrodites and green lines denote males. Dashed
lines denote the negative controls (TIR1-only on auxin) and solid lines denote DAF-degradation
with 1mM auxin treatment. Each line represents at least two biological replicates with total n =
183–235.
191
Patrick Phillips @patrickphillips.bsky.social · 06/11/2025
Make males live more than 400% longer and prevent sexual disfunction late in life?! We're down with it. Our latest preprint: Disruption of the insulin signaling pathway in C. elegans dramatically increases male longevity and enhances reproductive health late in life. www.biorxiv.org/content/10.1...
34215
Patrick Phillips @patrickphillips.bsky.social · 02/11/2025
Inspired by my recent workshop visit in Sicily, the lab had an Italian food potluck during lab meeting. I made pumpkin stuffed gnocchi in a nutmeg sage cream sauce, but we have no kitchen. So I finished the gnocchi in an electric tea kettle. Worked ok.
Bowl of gnocchi in cream sauce next to a tea kettle.
070
Patrick Phillips @patrickphillips.bsky.social · 02/11/2025
Grew up a huge Dodgers fan but the last serious game I watched was in grad school when Kurt Gibson made the greatest hit I’ve ever seen. So yes, I’ve turned on this baby after seeing the hoopla.
020
Patrick Phillips @patrickphillips.bsky.social · 31/10/2025
Happened to wear black today, so I got sucked into a lab Louvre heist Halloween dress up.
Picture of five people wearing berets and costume jewelry.
0292
Patrick Phillips @patrickphillips.bsky.social · 26/10/2025
This is nuts, because we know that we can use synthetic biology to optimize these “beasts” of burden. Not sure of the application. I have visions bacterially manned gates sorting the worthiness of other bacteria.
030
Reposted by Patrick Phillips
Roshni Patel @roshnipatel.bsky.social · 15/10/2025
I'm recruiting a postdoc for my group (based in beautiful Eugene, OR). Please get in touch if you're interested, esp if you'd like to chat at #ASHG25!
04242
Reposted by Patrick Phillips
Lab on a Chip @labonachip.rsc.org · 13/10/2025
Available to read via #OpenAccess The egg-counter: a novel microfluidic platform for characterization of Caenorhabditis elegans egg-laying pubs.rsc.org/en/content/a... Patrick C. Phillips et al @patrickphillips.bsky.social @uoregon.bsky.social @stephenbanse.bsky.social
pubs.rsc.org
The egg-counter: a novel microfluidic platform for characterization of Caenorhabditis elegans egg-laying
Reproduction is a fundamental process that shapes the demography of every living organism yet is often difficult to assess with high precision in animals that produce large numbers of offspring. Here,...
011
Patrick Phillips @patrickphillips.bsky.social · 06/10/2025
Very important paper for the geroscience hypothesis. Healthy aging is critical, even in the face of obvious disease states.
041
Reposted by Patrick Phillips
Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 03/09/2025
Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!
genetics-gsa.org
Homepage - Population, Evolutionary, and Quantitative Genetics Conference
Visit our website to learn more.
26443
Patrick Phillips @patrickphillips.bsky.social · 03/09/2025
Just out in press in eLife, a cool and brilliant piece of work by @amywebster.bsky.social: Gene expression variation across genetically identical individuals predicts reproductive traits. elifesciences.org/articles/106...
13611
Patrick Phillips @patrickphillips.bsky.social · 19/08/2025
New position in Developmental Neuroscience in the University of Oregon Department of Biology. There is also a neuroengineering search going on in the Knight Campus at the same time, so exciting buildouts in that area at the UO. academicjobsonline.org/ajo/jobs/30255
academicjobsonline.org
University of Oregon, Department of Biology
Job #AJO30255, 535561 Assistant Professor of Developmental Neuroscience, Department of Biology, University of Oregon, Eugene, Oregon, US
084
Reposted by Patrick Phillips
Will Ratcliff @wcratcliff.bsky.social · 14/08/2025
Come be my boss! My dept. at GT is searching for a new chair. Drop me a line if you are interested, I'd be happy to talk about this position, GT, ATL- anything. It's a drama-free department filled with cool people in a dynamic city. www.biosciences.gatech.edu/chair-search
biosciences.gatech.edu
Chair Search
Chair, School of Biological Sciences Georgia Institute of Technology, Atlanta The School of Biological Sciences of the Georgia Institute of Technology (“Georgia Tech”) invites applications for the pos...
05242
Reposted by Patrick Phillips
Roshni Patel @roshnipatel.bsky.social · 06/08/2025
Bittersweet to be leaving @docedge.bsky.social after a wonderful postdoc, but excited to share that I'm joining @uoregon.bsky.social next month as an Assistant Professor in the Department of Data Science.
2114628
Reposted by Patrick Phillips
Colette Delawalla, PhD @cdelawalla.bsky.social · 04/08/2025
Congress says they have our back...let's hold them to their word! All gas, no breaks this August with the 31 Days of Action campaign. Sign up for our daily action notes here: act.standupforscience.net/forms/31-day...
act.standupforscience.net
Join thousands of Science Defenders for our 31 Days of Action!
Every morning for the 31 days of August, let's take action together!
0307