iiinova — where your digital self keeps evolving

Patrick Boyle @patrickboyle.bsky.social · 27/01/2026

Any bio artists out here? I’m interested in commissioning 1-2 pieces, leaning more towards the art side but love stuff that is science-inspired... DM me if you're interested!

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Patrick Boyle @patrickboyle.bsky.social · 16/01/2026

I've heard biologists complain that AI isn't useful because new bio data doesn't make the models better... but what if AI is a mirror showing us that a lot of data isn't as insightful as we think it is? How do we identify experiments that are maximally informative to a model?

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Patrick Boyle @patrickboyle.bsky.social · 16/01/2026

When I close my eyes and dream about bioproducts this is what I see if you even care

Original Apple I in wooden case designed and built by Steve Wozniak

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Patrick Boyle @patrickboyle.bsky.social · 16/01/2026

Not to upset anyone but I'm coming down on the side of microplastics in the human body being mostly an experimental artifact until someone puts out stronger data: www.science.org/content/blog...

science.org

Are There Accumulating Microplastics in Human Tissue or Not?

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Patrick Boyle @patrickboyle.bsky.social · 15/01/2026

X is cooked I hope people I like are still here instead. Please don't make me go to LinkedIn

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Patrick Boyle @patrickboyle.bsky.social · 23/06/2025

💚 Some personal news… 💚 (1/2)

Last week I wrapped up at Ginkgo after 13 amazing years. It was, without a doubt, the best postdoc I could have asked for. I knew there was something special about Ginkgo’s founding team when I joined back in 2012, and I’m forever grateful that Jason, Reshma, Barry, Austin, and Tom took a chance on me back then. It’s been an incredible honor to be part of growing Ginkgo, going from a tiny pre-seed company, to seeing our work in fermentation tanks, field trials, and clinical trials. If you’ve been here, you’ll know that some of the most talented, creative people in the Boston area and beyond have made it a special place.

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lauren @lauren.rotatingsandwiches.com · 13/04/2025

evolution really went off with brassica oleracea

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Patrick Boyle @patrickboyle.bsky.social · 29/03/2025

Few papers perfectly intersect my interests better than this paper on advanced baseball bat designs via genetic algorithms from the Centre for Advanced Wood Processing mdpi-res.com/d_attachment...

mdpi-res.com

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Patrick Boyle @patrickboyle.bsky.social · 20/03/2025

Props to the guy playing a clearly AI-generated TikTok on loop in a public bathroom, will file that in my “dystopian vignettes” folder

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Patrick Boyle @patrickboyle.bsky.social · 14/03/2025

A new report I worked on for NAS on AI and biosecurity is out today - we looked at risks posed by SOTA AI and opportunities to use AI to improve biosecurity. It builds on a report we wrote back in 2018, which feels like a million years ago in AIxBio! nap.nationalacademies.org/catalog/28868

nap.nationalacademies.org

The Age of AI in the Life Sciences: Benefits and Biosecurity Considerations

Read online, download a free PDF, or order a copy in print.

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Patrick Boyle @patrickboyle.bsky.social · 10/03/2025

Since twitter is down I'll mention that I'd spend more time here if engagement was higher (with real people not the bot slop X has). Feels like tuning the algo to boost replies a bit more would be useful - my feed is mostly people shouting facts into the void

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Patrick Boyle @patrickboyle.bsky.social · 26/02/2025

Support for the Ribosome Panspermia Hypothesis grows unabated

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Patrick Boyle @patrickboyle.bsky.social · 17/02/2025

It's been just over a year, and either no new papers have been published with AI-generated rat balls, or the newer models are just that good at generating anatomically correct rat balls

It's that AI-generated figure of a rat with giant balls. You know the one

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Sri Kosuri @srikosuri.bsky.social · 08/02/2025

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

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Ginkgo Bioworks @ginkgobioworks.bsky.social · 06/02/2025

We're excited to announce our 2025 Ferment Series, an evolution of our flagship annual conference dedicated to advancing our mission of making biology easier to engineer! We can't wait to see you in Boston Read more: www.ginkgo.bio/resources/bl... Sign up for updates: www.ginkgo.bio/ferment-2025...

ginkgo.bio

We're Hosting Our 6th Annual Ferment as a Boston-based Conference Series | Ginkgo Bioworks

Headquartered in Boston, Ginkgo Bioworks uses the most advanced technology on the planet—biology—to grow better products. Our cell programming platform enables the growth of biotechnology across diver...

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Patrick Boyle @patrickboyle.bsky.social · 24/01/2025

It must be hard for designers to keep up with rapid tech changes for long-lasting stuff like airplane seats, but I wish I could’ve been a fly on the wall for the meeting where they locked in the seatback Ethernet jack

Closeup of an airplane seat with USB-A and Ethernet on the back

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Patrick Boyle @patrickboyle.bsky.social · 15/01/2025

Me in 2005: it would be fun to connect with my fellow students on the facebook Me in 2025: the new meta is getting your message out via tradwife accounts on xiaohongshu before either government sees it

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Patrick Boyle @patrickboyle.bsky.social · 15/01/2025

My feed here is way more academic than on twitter, so as an industry scientist I feel like this all the time

Meme of Hillary Clinton visiting an East Harlem apartment

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Patrick Boyle @patrickboyle.bsky.social · 11/01/2025

Just an update that no one new has been added. Thinking about trimming it down, tbh

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Patrick Boyle @patrickboyle.bsky.social · 08/01/2025

Here it is... it is exclusive, it is arbitrary, and membership will be determined solely by me. You should be upset if you are included, and also upset if you are not included go.bsky.app/JZc9HXe

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Patrick Boyle @patrickboyle.bsky.social · 06/01/2025

I'm afraid I'm losing the urge to post - Twitter gives me brain worms and Bsky is a little too...earnest? Is there a starter pack for science goblins?

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Hannah Ritchie @hannahritchie.bsky.social · 30/12/2024

Thank you, Jimmy Carter. This chart is on a log scale. This year there have been just 7 cases of guinea worm. ourworldindata.org/grapher/numb...

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Patrick Boyle @patrickboyle.bsky.social · 30/12/2024

Slack would be lethal if deployed in this environment

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Patrick Boyle @patrickboyle.bsky.social · 23/12/2024

If I'm staring at you it's because I'm waiting for you to notice that my eyelashes are higher volume thanks to my B STRUCTURAL VOLUMIZING + LENGTHENING MASCARA featuring Bolt Threads' recombinant B-silk™️, a product of Haus Labs by Lady Gaga www.hauslabs.com/products/b-s...

hauslabs.com

B STRUCTURAL VOLUMIZING + LENGTHENING MASCARA

Our mascara delivers 5X volume. Powered by vegan B-Silk and Rice Protein, it nourishes and strengthens, never clumps/flakes, and provides 12-hour wear for sensitive eyes.

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Patrick Boyle @patrickboyle.bsky.social · 23/12/2024

Making academic pay more competitive with industry will make academia more diverse, but until then industry (especially startups if you have equity) are the key to upward mobility in science. Science doesn't need to make you rich but it shouldn't be designed to keep you poor either

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Patrick Boyle @patrickboyle.bsky.social · 20/12/2024

My favorite academic trope on here is when y’all skeet about the burdens of academia and it’s all extremely normal work stuff like answering an email

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Patrick Boyle @patrickboyle.bsky.social · 18/12/2024

❤️ "tinfoil shield" as a term. If it was up to me, every workshop on science policy would have a buzzer that would go off when a scientist says "we should educate the public more" on an issue that is value-driven. Then you have to sit in a penalty box and read about why the deficit model doesn't work

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Patrick Boyle @patrickboyle.bsky.social · 14/12/2024

If the world weren’t so weird about GMOs we could have a new fruit dropping every week

Street ad for the “Envy” apple - “Hey, Boston! Get ready to taste your new favorite apple”

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Jake Wintermute @synbio1.bsky.social · 13/12/2024

Been this way since asilomar back in '75

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Patrick Boyle @patrickboyle.bsky.social · 05/12/2024

Ok I love precision fermentation but what if we just made all the milk the country needs with a single megacow

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Jason Kelly @jasonrkelly.bsky.social · 30/11/2024

We need to speed up design-build-test cycles in bioengineering

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Patrick Boyle @patrickboyle.bsky.social · 28/11/2024

Took butter out of the fridge so that it’s room temp when I need it later

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Patrick Boyle @patrickboyle.bsky.social · 25/11/2024

Boston folks should check out our monthly Engineering Biology Club event - next one is coming up on Thursday 12/5 at 5:30PM. Come for the free food, and sign up for a lighting talk if you want to jam with us! Hosted by the one and only @synbio1.bsky.social www.ginkgobioworks.com/learn/engine...

Title card for Ginkgo Bioworks' Engineering Biology Club. Background photo of a pin that says "Born to gene edit" on it

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Patrick Boyle @patrickboyle.bsky.social · 25/11/2024

Welcome to Ribosome Monday, something that's definitely real and not something I made up for Bluesky - please reply with your most fringe ribosome thoughts - mine is that aliens would likely categorize life on Earth as ribosomal life; all other biology is just a vehicle for ribosome proliferation

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Patrick Boyle @patrickboyle.bsky.social · 22/11/2024

Trying out starter packs with a @techbio.bsky.social starter pack - join the TBT slack if you'd like to be added! go.bsky.app/PqdYxpr

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Patrick Boyle @patrickboyle.bsky.social · 21/11/2024

One must consider that if DNA data storage takes off we will someday store sequencing data as DNA

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Patrick Boyle @patrickboyle.bsky.social · 20/11/2024

Wholeheartedly agree with this, and would add - in your position, are you adding new people to the first rung of the ladder that you're on? One of the things I'm proudest of at Ginkgo is seeing non-PhDs come in and earn PhD level roles at Ginkgo and elsewhere

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Keith Robison @omicsomics.bsky.social · 20/11/2024

RFP: Request for Problems Announcing Ferment’s $20M studio fund for bio-empowered companies www.ferment.co/media/rfp-re...

ferment.co

FermentCo

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Patrick Boyle @patrickboyle.bsky.social · 19/11/2024

Which ✨AI✨ tool do I have to subscribe to in order to successfully paste a table into a document without messing up the formatting

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Jake Wintermute @synbio1.bsky.social · 19/11/2024

I made a demo notebook and recorded a video tutorial for how to use the AA-0 protein sequence model from Ginkgo AI In the PETase Mask Fill Challenge, we compare the performance of 3 different models for modifying a plastic-degrading enzyme foundrytheory.substack.com/p/the-petase...

foundrytheory.substack.com

The PETase Mask Fill Challenge

How to Engineer Protein Sequences with AA-0 and the Ginkgo AI API

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Kyle Morgenstein @kylem.bsky.social · 19/11/2024

not to give a 2nd day of follow-back discourse but a lot of people follow starter packs before they add a profile picture/bio/post anything. I’m sure I would be thrilled to follow many of you, and I usually follow after good interactions with related people! hopeful to see this platform take off :)

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Patrick Boyle @patrickboyle.bsky.social · 19/11/2024

Ben Affleck comes close to saying what I’ve been thinking, so I’ll pretend we agree - ethically trained AI will be a great creative tool for artists, but the equivalent of word art for the rest of us - janky, unprofessional, but good enough to get a point across

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Sebastian S. Cocioba @atinygreencell.bsky.social · 18/11/2024

I am ***absurdly*** excited to announce the launch of a new funding opportunity through Experiment dot com!!! You have one month to pitch something wonderful in the realm of plant biology/biotech research and education. $10,000 max grant. PLEASE RE-POST + SHARE!!! 1/3 experiment.com/programs/pla...

experiment.com

Plant Biology Exploratory Research Microgrant | Experiment

For Science!

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