Puttering around with some ideas for future experiments on our autonomous lab, I realized a potential software engineering gap that in my ve...

An interesting new approach to short read RNA-Seq library preparation bobbed into view this week, using click chemistry to barcode samples b...

At the Datapoints Summit, speakers showed where AI can improve drug discovery—and why better data, validation, and scientific judgment remain essential for lasting progress.

Googling on some keywords from a social media post led to an interesting PNAS article from 2019 on two fungi which can infect the spotted la...

This week we hosted the first REAL (Readiness & Engagement For Automated Labs) Summit; today that was followed by Ginkgo Datapoints Summit. ...

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

In my previous post about the Model Hardware Standard from Anthropic , I mentioned some exploration I've been running on instrument APIs.  ...

An interesting preprint showed up last week in the autonomous agent-driven experimentation space - an area I'm paid to be very interested in...

The Society for Industrial Microbiology (SIMB) annual meeting in Austin the first week of the month was great fun.  I caught up with two War...

PacBio had a major shakeup early this month. First came a large round of layoffs, which caught several individuals who were very much the fa...

I wish to highlight an interesting new preprint from a group at Danish Technical University which explores the schmutz in PCR reactions, d...

Steady-state RNA abundance measurements mask the synthesis and decay rates that shape gene expression. Analog intrinsic recoding sequencing (AIR-seq) repurposes the base-pairing properties of N4-hydro...

Last week news broke that Element Biosciences had won a patent lawsuit against Illumina, and that it affected MiSeq.  MiSeq????  How did a p...

A recent publication in Molecular Cell involving Fiber-Seq caught my attention, though I've since discovered this preprinted over a year ag...

Okay, this is one of those cases where I kvetch about other people not having built the tools I want to use - perhaps a bit of a insufferabl...

I caught up by teleconference recently with Countable Labs CEO Giovanna Prout, fresh off Countable Labs' $26M equity fundraising - a round w...

An interesting news item this week is that BioNano Genomics has appointed Alex Hastie as Chief Scientific Officer.  Hastie is an obvious cho...

Another interesting preprint that fits several recent themes - genome minimization, discontinuation of products - comes from a Japanese grou...

There's an interesting new preprint from Jay Shendure's lab which introduces the technique of Shred-Seq, which is a Cas3-driven approach to...

About a year ago we took a family vacation to the Netherlands with a prime goal to see tulips - and tulips we did see!  Even a rainy day (wh...

I've loved the n6tec icon96 instrument since they first tipped me about it several years back.  The idea of running 96 independent PCRs in p...

After Roche's AGBT presentation, a key question for many is "who is going to buy an Axelios?".  Below are some thoughts on the topic, based ...

In my current role I spend a lot of time on LinkedIn. A core task is to identify possible customers, and LinkedIn is rich hunting ground. I'...

In this Software Deep Dive episode, we talk with Dr. Bede Constantinides (University of Birmingham) about Deacon, a tool for removing host DNA reads from metagenomic datasets. We discuss why host read

Analysis of nuclear and mitochondrial genomes from archaeological canid remains found across Europe and Anatolia shows that a genetically homogeneous dog population was already widely distributed acro...

Genome-wide analysis shows European dogs existed by 14,200 years ago, were already genetically distinct, received less Neolithic Southwest Asian admixture than humans did and contr...

Even before new CEO Francis Van Parys took the reins at Oxford Nanopore with the start of the month, the company had made yet another primin...

Run biotech protocols on Ginkgo Bioworks' autonomous cloud laboratory. Cell-free protein expression and more — order on demand.