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Osvaldo Burastero

@osvalb.bsky.social
870 followers 949 following 35 posts

bio-rshiny.com

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Osvaldo Burastero @osvalb.bsky.social · 10/06/2026
Do you want to study the stability of a designed protein that doesn't unfold below 90 ºC 🔥? Combine a denaturant and temperature and then analyse the results with our newest tool: CheMelt 🧪 Online: - spc.embl-hamburg.de/app/chemelt As Docker image (faster): - hub.docker.com/r/emblspc/ch...
Abstract illustration showing several thermal unfolding curves at different denaturant concentrations
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Osvaldo Burastero @osvalb.bsky.social · 30/03/2026
Interested in protein biophysics?🧪 Sign up for the @springernature.com webinar (08/04) where we will present the MOSBRI project outcomes @mosbri.bsky.social, including the eSPC platform (spc.embl-hamburg.de) and the Molecular Biophysics Database (mbdb-data.org) 🙌 Info here: tinyurl.com/rdfsp4nv
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Osvaldo Burastero @osvalb.bsky.social · 19/02/2026
Do you have to create a scientific poster? 🧪 I have created a basic Figma template for it. Hope it helps 👐: github.com/osvalB/figma...
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SPC Facility & Garcia-Alai Lab @spcembl.bsky.social · 29/01/2026
New protocol out now! 📕🖊️🔍 A practical workflow for analyzing CD thermal unfolding of short RNAs — from SVD decomposition to two-state fitting to extract melting temp and enthalpy with ChiraKit. A must-see if you’re working with RNA structure and CD data. DOI: 10.1007/978-1-0716-5084-4_12 
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SPC Facility & Garcia-Alai Lab @spcembl.bsky.social · 17/09/2025
@mpimarinemicrobio.bsky.social @cssbhamburg.bsky.social
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SPC Facility & Garcia-Alai Lab @spcembl.bsky.social · 15/09/2025
We’re looking for a GL! Join us at EMBL Hamburg! 🧫🦠🧬 The position will be based at CSSB @cssbhamburg.bsky.social , an interdisciplinary research centre focused on infection biology, and will be integrated into EMBL's research programme. @embl.org Find out more and apply here: lnkd.in/dJU9pee7
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EMBL @embl.org · 14/08/2025
EMBL-EBI ARISE fellow @melanieschneider.bsky.social & EMBL Grenoble’s Marquez team developed EnsembleFlex 🖥️! It can analyse flexibility, identify protein states, and show drug binding, providing new insights into protein dynamics! doi.org/10.1016/j.st...
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Osvaldo Burastero @osvalb.bsky.social · 13/08/2025
Do you want to analyze mass photometry (MP) count data with Python scripts? Try pyPhotoMol, a package to process, fit, and visualize the MP data 👨‍💻 github.com/osvalB/pypho... pyPhotoMol is derived from PhotoMol, our web tool for MP: spc.embl-hamburg.de/app/photoMol #massphotometry #Python #code
Simulated mass photometry results showing count distributions at a constant concentration of A (150 kDa) and seven different concentrations of B (30 kDa). B free is under the limit of detection (40 kDa). A and B interact with an equilibrium dissociation constant (Kd) of 1 nM.Screenshot of the pyPhotoMol package repository (https://github.com/osvalB/pyphotomol)
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Osvaldo Burastero @osvalb.bsky.social · 12/06/2025
Happy to present the next tool under development. KinGenie, for binding kinetics. It already supports biolayer interferometry input files. Try it here: spc.embl-hamburg.de 🎉🎉🧪🧪
spc.embl-hamburg.de
eSPC platform
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Osvaldo Burastero @osvalb.bsky.social · 28/04/2025
ChiraKit, our tool for circular dichroism, has been published in NAR 🎉🎉👨‍🔬👨‍🔬. @narjournal.bsky.social
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Clarissa Czekster @cczekster.bsky.social · 24/04/2025
Just want to say thanks to @spcembl.bsky.social for developing ChiraKit and allowing quick and informative analysis of CD data - more here www.biorxiv.org/content/10.1... best news of the day today as we were stuck with beautiful but hard to analyze data 🙂 #scienceisawesome
biorxiv.org
ChiraKit, an online tool for the analysis of circular dichroism spectroscopy data
Circular dichroism (CD) spectroscopy is an established biophysical technique to study chiral molecules. CD allows investigating conformational changes under varying experimental conditions and has bee...
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Osvaldo Burastero @osvalb.bsky.social · 14/02/2025
Interested in antimicrobial resistance and drug discovery? Attend the talk of my colleague and partner Tania Szal 😊 Monday 17th at 8:30. Platform: protein-small molecule interactions I #BPS2025
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Osvaldo Burastero @osvalb.bsky.social · 14/02/2025
Looking forward to making new connections at #BPS2025👨 Meet me at poster B38 on Tuesday 18 Feb 13:45. Session "protein stability folding and chaperones"
espc poster details BPS conference banner
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Osvaldo Burastero @osvalb.bsky.social · 11/02/2025
Just finished a science poster (in Figma) and wanted to share the template I used! 🎨 Hope it's useful: github.com/osvalB/figma...
Poster template done in Figma
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Reposted by Osvaldo Burastero
EMBL @embl.org · 03/02/2025
Scientists at University of Buenos Aires, EMBL Hamburg, and others mapped yerba mate’s genome, providing surprising facts about its biochemistry and evolution of caffeine biosynthesis. 🧉🧬🧪 Find out more: www.embl.org/news/science... @spcembl.bsky.social
A cup of yerba mate on a wooden surface and some dried yerba mate next to it.
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Osvaldo Burastero @osvalb.bsky.social · 31/01/2025
After many months of gathering user feedback and improving our software, we think it's time to share it with the community. Enjoy our latest tool 🥳 , and stay tuned for the next one 😉
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Osvaldo Burastero @osvalb.bsky.social · 31/01/2025
Our colleagues in Prague have released a database for molecular biophysics data - mbdb-data.org! 🌍📊 A great step forwards FAIR data in biophysics. 🙌✨ @mosbri.bsky.social
mbdb-data.org
Molecular Biophysics Database
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Instruct-ERIC @instruct-eric.bsky.social · 30/01/2025
Instruct now has two R&D calls open - aimed at growing and advancing the global structural biology toolkit! - The pilot award is open to Early Career Researchers, with up to €15,000 available for any topic - The TechDev call in AI research awards up to €30,000 instruct-eric.org/rd-project-a...
instruct-eric.org
R&D project awards - Instruct-ERIC
Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to all European researchers.
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Osvaldo Burastero @osvalb.bsky.social · 29/01/2025
Are you working with circular dichroism (CD)? Check out the latest update to our ChiraKit tool, now with 10 tutorials to get you started! 🚀 Try it here: spc.embl-hamburg.de/app/chirakit
An abstract representation of what happens during a circular dichroism measurement. Left- and right-circularly polarized light passes through the sample. One of the components is more absorbed.
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Centre for Structural Systems Biology CSSB @cssbhamburg.bsky.social · 09/01/2025
The Sondermann group and collaborators @univofmaryland.bsky.social have identified a new family of bacterial enzymes termed diDNases. The research received a Breakthrough Article designation from Nucleic Acids Research. Find out more: t1p.de/i07ua
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Osvaldo Burastero @osvalb.bsky.social · 15/12/2024
Journalist friend: you pay to publish your work? 😶 Me: yes, and we also review for free, and pay to read Friend: are scientists okay? Idk 😅
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Osvaldo Burastero @osvalb.bsky.social · 06/12/2024
Apply now to learn about binding kinetics at the Institut Pasteur (April 2025) 🧪😁
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Reposted by Osvaldo Burastero
Kate Michie @kmichie.bsky.social · 17/11/2024
So many people added to pack 1 this weekend we had to make pack 2. Makes sure you refresh for followers on pack one to see them all! 🧶🧬 go.bsky.app/DDetSBp
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Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 25/11/2024
Look who's here @pnas.org ✔️ @science.org ✔️ @naturecellbiology.bsky.social ✔️ @natrevgenet.bsky.social ✔️ @naturebiotech.bsky.social ✔️ @naturemicrobiol.bsky.social ✔️ @naturechemistry.bsky.social ✔️ @genesdev.bsky.social ✔️ @cellchembiol.bsky.social ✔️ @genomeresearch.bsky.social ✔️ @jcellbiol.bsky.social ✔️
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Osvaldo Burastero @osvalb.bsky.social · 22/11/2024
Anyone looking for a postdoc position? Apply to join our group in EMBL Hamburg 😊🧪
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Reposted by Osvaldo Burastero
EMBL-EBI @ebi.embl.org · 19/11/2024
Not enough bioinformatics in your Bluesky feed? We’ve got you covered. Follow us for our latest news, exciting life science research, updates from our data resources, new tools and training resources. Haven't heard of EMBL-EBI? Take a look at what we’re working on. www.ebi.ac.uk/about/our-im...
ebi.ac.uk
Our impact
We provide open data that helps scientists understand life and that informs solutions to real-world problems, such as infectious diseases, climate change and food security.
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Osvaldo Burastero @osvalb.bsky.social · 18/11/2024
Just out! 🥳🥳 Great work done at the @spcembl.bsky.social to understand clathrin-mediated endocytosis. We investigated how clathrin and adaptor proteins interact in vitro and in vivo. Kudos to the 1st author @lucasdefelipe.bsky.social! www.nature.com/articles/s41... www.embl.org/news/science...
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Osvaldo Burastero @osvalb.bsky.social · 13/11/2024
Assisted to a meeting about FAIR (Findable, accessible, interoperable and reusable, or Foundational AI ready, depending who you ask😅) data. Main takeaway: FAIR is far in biophysics
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Osvaldo Burastero @osvalb.bsky.social · 13/11/2024
More starter packs. This time for biophysics 🧪
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Osvaldo Burastero @osvalb.bsky.social · 13/11/2024
Highly recommended for those interested in structural biology 👌
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