Full program and schedule for the AI x Biology Summit on October 21, 2026 at New York Genome Center. Explore sessions on AI-driven discovery, protein engineering, drug design, and precision medicine.

Ageing reflects progressive decanalization of mammalian cell identity, driven by erosion of a regulatory grammar written during development.

Nature Genetics - Pierre Chambon (1931–2026)

The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...

How sickle cell anemia led the quest to edit the human genome while patients endured decades of racial discrimination and medical neglect.In December 1904, Walter Clement Noel, a dental student from G...

This Review discusses how rare-disease-causing variants in the noncoding genome impact gene regulation, why these examples are so few and how new approaches could accelerate discovery of noncoding var...

House Appropriations Committee Ranking Member Rosa DeLauro (D-CT-03) has learned that officials at the Department of Defense (DoD) are working to divert billions of dollars from the National Institute...

Many advances in cancer treatment depend on discoveries made decades earlier. In this Comment, Murphy et al. discuss the histories of EGFR, HER2, CDK4/6 and RAS, highlighting how long translation can ...

Single-molecule long-read sequencing of human sperm reveals variation in recombination across donors and that a substantial fraction of non-crossover gene conversions arises before meio...

Dr. Dan-Avi Landau, a world-renowned cancer researcher and pioneering geneticist, has been appointed inaugural chair of the newly created Department of Systems and Computational Biomedicine. The new ...

What We Can Learn from Singapore’s Investments in Research and Public Health

Nature Reviews Genetics, Published online: 03 August 2026; doi:10.1038/s41576-026-00993-9Ageing has often been conceptualized as a gradual, linear decline, yet growing evidence suggests it unfolds through dynamic, stage-specific transitions. In this Perspective, the authors examine such evidence across molecular and physiological systems and discuss analytical frameworks to identify non-linear transitions.

Nature - The international collaboration of the Human Cancer Models Initiative presents a comprehensive resource of next-generation cancer models from 2,780 donors with 25 cancer types and...

The next generation of cancer research models has arrived. An international consortium led by CSHL and @NorthwellHealth has developed more than 150 organoid models representing actual patient tumors s...

Experimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving mutations in shaping the earliest stage...

Most genetic variants associated with complex traits are hypothesized to regulate gene expression. To understand the genetics underlying gene expression variability, we characterized 14,324 RNA-sequen...

In a survey, 93% of cancer researchers who study disparities said federal policy changes have affected them. Funding is harder to come by and they worry it's slowing progress in their field.