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Nico Dosenbach

@ndosenbach.bsky.social
2K followers 2.6K following 153 posts

David M. & Tracy S. Holtzman Professor, Neurology @ WashU School of Medicine; precision neuroimaging, network plasticity, BWAS ≠ fMRI, action mode; #neuroscience #neurology #openscience #science dosenbachlab.wustl.edu

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Reposted by Nico Dosenbach
Kristina Visscher @visscherlab.bsky.social · 12/10/2026
This was a very nice discussion of the meta-science behind what we currently call ADHD. They cite @ndosenbach.bsky.social and @drdamienfair.bsky.social 's excellent work on the topic www.nytimes.com/2026/09/29/s...
nytimes.com
What if A.D.H.D. Isn’t About Attention at All? (Gift Article)
Evidence suggests that it really affects what psychiatrists like me call sustained engagement — an important difference in understanding how to think about the condition.
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Haydon, frightfully @haydonmp.bsky.social · 29/09/2026
Really important and useful article.
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Awais Aftab @awaisaftab.bsky.social · 29/09/2026
I am doing a series of articles (“Therapeutic Window”) for the Science desk at The New York Times. The first article is about whether ADHD is better understood as a disorder of “attention” or something else: www.nytimes.com/2026/09/29/s...
nytimes.com
What If A.D.H.D. Isn’t About Attention at All? (Gift Article)
Evidence suggests that it really affects what psychiatrists like me call sustained engagement — an important difference in understanding how to think about the condition.
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Reposted by Nico Dosenbach
Michael Okun @michaelokun.bsky.social · 16/09/2026
What resonated with me from today’s DBS Think Tank session on neuromodulation of mood and cognition was how quickly we are moving from simply observing these remarkably complex human circuits to recording, understanding and potentially modulating them in the real world.
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Michael Okun @michaelokun.bsky.social · 17/09/2026
What resonated with me most from this morning’s DBS Think Tank session on sEEG-guided neuromodulation was the sense that we are moving beyond simply asking where to stimulate and toward understanding the circuits, signals and physiology that can tell us how to stimulate better.
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Michael Okun @michaelokun.bsky.social · 17/09/2026
What resonated with me from today’s DBS Think Tank session on electrophysiology-guided neuromodulation was how rapidly we are moving from simply recording brain signals to understanding which physiology actually matters and then using it to guide therapy.
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Michael Okun @michaelokun.bsky.social · 17/09/2026
“Deep brain stimulation” can sound frightening; “brain pacemaker” is simpler, more familiar and may better communicate what we are actually trying to do: use an implanted device to help restore function and improve lives.
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Michael Okun @michaelokun.bsky.social · 18/09/2026
One of my favorite moments from this morning’s DBS Think Tank came from Nico Dosenbach, who reminded us of the famous story of Charles Steinmetz and Henry Ford. The chalk marked “X” on exactly the right spot; and told the engineers where to make the repair. Check out the invoice.
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Michael Okun @michaelokun.bsky.social · 18/09/2026
What resonated with me from this morning’s DBS Think Tank session on advanced imaging in neuromodulation was how imaging is rapidly evolving from a picture of anatomy into a roadmap of the circuits we want to understand and modulate.
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Michael Okun @michaelokun.bsky.social · 18/09/2026
What resonated with me from the final session of DBS Think Tank XIV on digital health-guided neuromodulation was how rapidly digital tools are beginning to connect the entire therapeutic journey, from predicting and planning to programming and long-term monitoring.
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Micaela Chan @micaelachan.bsky.social · 01/09/2026
Combining data to study lifespan brain aging is tempting: more data and wider age range! But mixing data across scanners/protocols without proper harmonization can bias age effects, including studies using high-quality HCP data. Imaging Neuroscience🔔doi.org/10.1162/IMAG.a.1338
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Gagan Wig @gaganwig.bsky.social · 01/09/2026
Using HCP data to examine lifespan differences in functional brain activity or network organization? See below! A reminder that even subtle differences in data acquisition between cohorts can change our conclusions. This issue will only become more relevant as we pool neuroimaging datasets.
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Itai Yanai @itaiyanai.bsky.social · 21/08/2026
The future of AI should not be determined by the dreams of a small group of technologists, but by democratic choices about the kind of society we wish to build. –Daron Acemoglu, Nobel Prize-winning MIT Professor
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Jianxun Ren @jianxunren.bsky.social · 05/08/2026
This essentially organizes the findings from our Nature and Nature Neuroscience papers into one picture. nature.com/articles/s41586-025-10059-1 nature.com/articles/s41...
nature.com
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
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Jianxun Ren @jianxunren.bsky.social · 05/08/2026
Honored to be named the runner-up for the Science & PINS Prize for Neuromodulation, with my essay now published by @science.org science.org/doi/10.1126/... The essay lays out how mapping the brain's functional circuits lets us move neuromodulation from deep toward the brain surface.
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washuonr.bsky.social @washuonr.bsky.social · 10/07/2026
From @ndosenbach.bsky.social @washuneurology.bsky.social, @smarek0502.bsky.social @washu.edu and team: A family’s financial situation + neighborhood resources/opportunities had the strongest connection to brain development, and IQ had no correlation with brain structure/function.
bit.ly
Socioeconomic factors linked to lasting imprint in kids’ brains | WashU Medicine
Sleep, screen time and stress — but not IQ — are also linked to children’s brain features.
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WashU Medicine Neurology @washuneurology.bsky.social · 08/07/2026
ICYMI: Timothy Miller, MD, PhD, spoke to @stlmag.bsky.social about his work on tofersen, a treatment for a genetic form of ALS. "Washington University is an incredible environment to do neurodegenerative disease research." Read the article and listen to The 314 Podcast now: bit.ly/4ecTfGi
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WashU Medicine Neurology @washuneurology.bsky.social · 06/07/2026
New research from Nico Dosenbach, MD, PhD, and colleagues published in @science.org found that socioeconomic status is one of the biggest factors impacting the development of kids' brains — more than even IQ, parenting style or health history. Read more: bit.ly/4eelc1K
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WashU Medicine Neurology @washuneurology.bsky.social · 30/06/2026
Randall Bateman, MD, & David Holtzman, MD, received the 2026 American Innovator Award from the Bayh-Dole Coalition. It honors their decades of work that has transformed Alzheimer's disease diagnosis. medicine.washu.edu/news/bateman-and…
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Laura Helmuth @laurahelmuth.bsky.social · 23/06/2026
Statement by @sciamunion.bsky.social on Springer Nature's sale of Scientific American and massive editorial layoffs right before a successful union vote is counted. www.wgaeast.org/wgae-scienti...
wgaeast.org
WGAE-Scientific American Union Statement on Springer Nature’s Sale and Layoffs | Press Room
The following is a statement from Writers Guild of America East members at Scientific American on today’s decision to sell Springer Nature and lay off staff: “Earlier today in an all-staff meeting we ...
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Evan Gordon @gordonneuro.bsky.social · 23/06/2026
A great resource! We've been using NSI to quality-control all of our recent data.
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Michael Okun @michaelokun.bsky.social · 20/06/2026
The Parkinson's Plate: A Health and Diet Guide to Manage Your Journey. Pre-order is now open for October 1st on Amazon. cutt.ly/Jt2RlrzH
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Dr. Nico Dosenbach & co. @dosenbachlab.bsky.social · 20/06/2026
What's the bottom line? @smarek0502.bsky.social on @smerconish.bsky.social about what affects children's brains the most science.org/doi/10.1126/...
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Nico Dosenbach @ndosenbach.bsky.social · 16/06/2026
Someone asked for stats comparing the two panels, which made me realize they hadn't paid attention to the axis labels. So I replotted the data with a tweaked logic. If the model predicts the variable it was trained on better left upper triangle, if it predicts the other better right lower. 💥💥💥 Boom!
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Nico Dosenbach @ndosenbach.bsky.social · 16/06/2026
Someone asked for stats comparing the two panels, which made me realize they hadn't paid attention to the axis labels. So I replotted the data with a tweaked logic. If the model predicts the variable it was trained on better left upper triangle, if it predicts the other better right lower. 💥💥💥 Boom!
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Nico Dosenbach @ndosenbach.bsky.social · 14/06/2026
We've known that socioeconomics (SES) matters for the 🧠. New & 🤯 is that SES drowns out all other brain associations, incl. IQ. If you train an algorithm to predict IQ from brain data, it's still way better at predicting SES. Science Mag: www.science.org/doi/10.1126/... @smarek0502.bsky.social 👀🧵👇
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Mary Elizabeth Sutherland @meharpist.bsky.social · 19/06/2026
How does the brain build sentences? A recent @nature.com paper combined wide-scale recordings of single neurons with natural language processing models and found that there are specific neurons that only care if a word is a noun, or if a phrase is ending 🧪 www.nature.com/articles/s41...
nature.com
Mapping the neuronal building blocks of human language with language models - Nature
Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the...
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Dr. Nico Dosenbach & co. @dosenbachlab.bsky.social · 19/06/2026
$$$ is more strongly associated with the brain than IQ: science.org/doi/10.1126/... @smarek0502 @smerconish
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Millie(let) @gyro.bsky.social · 18/06/2026
oh so I'm losing my capacity to think because of life stress? yeah that tracks, that adds up. makes more sense than blaming it on long-COVID I think
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Lucinda Sisk @lucindasisk.bsky.social · 14/06/2026
🧠‼️ Socioeconomic variables show the strongest associations with the brain out of 649 measures—surpassing cognition and mental health. Grateful for the chance to write a perspective with @ted-satterthwaite.bsky.social about @smarek0502.bsky.social and team's important findings! tinyurl.com/bdhk6bc8
science.org
Childhood environments shape the brain
Socioeconomic factors top the list of influences on children’s brain structure and function
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anil oza @aniloza.bsky.social · 17/06/2026
A 20 year study on 2 NIH diversity programs in Science Advances shows they doubled undergrads' odds of getting a Ph.D. That is, before the funding for those programs and for the study itself was terminated last year: www.statnews.com/2026/06/17/n...
statnews.com
NIH diversity programs doubled undergraduates’ odds of getting a Ph.D., 20-year study finds
A new study found that two diversity-oriented programs supported by the NIH doubled the odds that an undergraduate would earn a Ph.D.
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Scott Marek @smarek0502.bsky.social · 11/06/2026
What matters most for childhood brain organization? We analyzed 649 variables. The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers. Even brain-IQ associations were better explained by SES. In Science today: www.science.org/doi/10.1126/...
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Albert and Mary Lasker Foundation @laskerfdn.bsky.social · 16/06/2026
🧪Team provides valuable insights into the effects of the environment on brain development. In Science Magazine it found that across adolescents, neighborhood-level socioeconomics have the strongest brain-wide association: ow.ly/30Nx50ZcijN Nico Dosenbach Brenden Tervo-Clemmens Damien Fair
Map from the primary literature, which pinpoints neighborhood socioeconomics linked to brain-wide association patterns.
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Nico Dosenbach @ndosenbach.bsky.social · 16/06/2026
How are they programming these bots?
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Badr AlKhamissi @bkhmsi.bsky.social · 16/06/2026
🚨 New Preprint! 🧠 We gave an AI model one simple rule: rearrange your neurons so that nearby ones respond alike. We never told it what a face, a voice, or a sentence was. It grew brain-like maps for all three anyway. 🧵👇 🌐 Website: topo-omni.epfl.ch
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Nico Dosenbach @ndosenbach.bsky.social · 16/06/2026
Eugenics was stupid in the 1920s when they also thought you could breed for human intelligence as easily as for fur color in guinea pigs. To still be riding that train in 2020 is shockingly stupid. That's on top of it always having been evil.
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Amber Ying 應 緣 @amberying.com · 16/06/2026
This clip briefly mentions that the genetic basis of IQ is complicated, but I am going to link a study that shows that socioeconomic status has a MUCH stronger effect on IQ than brain regions. www.science.org/doi/10.1126/...
science.org
Patterns of brain-wide associations reflect socioeconomics
Previous brain-wide association studies (BWAS) have linked specific environmental and behavioral variables to brain variability. In this work, we mapped 649 variables to children’s brains and compared...
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Language Learning Matters @llmllc.bsky.social · 16/06/2026
Timely. bsky.app/profile/smar...
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heartpunk (sophie!!) @heartpunk.com · 16/06/2026
this has been scaring the shit outta me ngl
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Haydon, frightfully @haydonmp.bsky.social · 16/06/2026
lol incredible that your post and this one were right next to one another in my feed
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Lorenzo Lorenzo-Luaces, PhD @lluaces.bsky.social · 16/06/2026
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Nico Dosenbach @ndosenbach.bsky.social · 16/06/2026
i simplified the visualization
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Andrea Stocco @andreastocco.com · 16/06/2026
This is mind-blowing
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Nico Dosenbach @ndosenbach.bsky.social · 16/06/2026
@ent3c.bsky.social
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Nico Dosenbach @ndosenbach.bsky.social · 16/06/2026
@tervoclemmensb.bsky.social @drdamienfair.bsky.social @hertinglab.bsky.social @kharloews.bsky.social @roselynechauvin.bsky.social @samkrimmelneuro.bsky.social @sarahepaul.bsky.social @nasiametoki.bsky.social @julia-monk.bsky.social @gordonneuro.bsky.social @benjaminkay.bsky.social
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Benjamin C. Kinney @benjaminckinney.com · 14/06/2026
Today in IQ is BS!
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Yvonne Lam @yvonnezlam.bsky.social · 16/06/2026
sharing to read later (h/t @grimalkina.bsky.social)
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Cat Hicks @grimalkina.bsky.social · 15/06/2026
Saving this to my zotero so I can reference it across my work and organize my library aka using the devil machine for lazy liars according to bsky historians
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Royal Holloway Sleep Lab @sleep-rhul.bsky.social · 15/06/2026
New research shows that neighborhood socioeconomic conditions, not IQ, are the strongest, most pervasive influences on children’s brain structure and function, echoing patterns linked to sleep loss and stress. @alice-gregory.bsky.social @jakketamminen.bsky.social www.science.org/doi/10.1126/...
science.org
Patterns of brain-wide associations reflect socioeconomics
Previous brain-wide association studies (BWAS) have linked specific environmental and behavioral variables to brain variability. In this work, we mapped 649 variables to children’s brains and compared...
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