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Nick Chiappini 🏳️‍🌈🧪

@ndchiappini.bsky.social
2K followers 1.3K following 694 posts

Lover of weird rxns, reactive intermediates, hockey (mostly 🐧and🐙)and equitable sci. Asst Prof at UNCW. Queer AF. Ligand appreciator. Bird and space nerd. ChemSky. He/him

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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 21/08/2026
Time to channel Jay Kochi* *setting up an iron-catalyzed cross-coupling
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 15/08/2026
"people hate the new logo! I bet condescending to them will fix things!" Incredible work
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 31/07/2026
I'd mind the fundraising text pleas way less if they weren't all five paragraph essays of guilt-tripping and hyperbole. Give me a tight two sentence sell. Isn't this what you pay all that money to consultants for?
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 07/06/2026
Drag queen called Mrs. Kasha S. Rule - "There's ALWAYS time for an absorption"
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 07/06/2026
Drag queen called Molly B. Denim whose catchphrase is "You're telling me this nitrogen is ace?"
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 05/06/2026
This housane is a homeane
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Scott Bagley @bagphos.bsky.social · 04/06/2026
2+2 =4 cyclobutane Really nice work from Kevin Brown and Co at Indiana out in @angewandtechemie.bsky.social Densely functionalized cyBu with handles for additional derivatives - good dr as well. Nice job by all #ChemSky
onlinelibrary.wiley.com
Reenvisioning the De Mayo Reaction: A Boron‐Enabled Cycloaddition Approach
An oxa-boracycle conformational lock strategy enables photocatalytic [2+2] cycloaddition to afford densely substituted cyclobutylboronates. The conformational constraint suppresses triplet relaxation...
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 24/05/2026
Yumm. A smoken salmon crêpe is absolutely what I needed today
A delicious looking crepe with smoked salmon, creme fresh with dill, capers, and sliced egg
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Scott Bagley @bagphos.bsky.social · 19/05/2026
So we all know acid can remove a BOC… What if you have acid labile groups? Check out this #PfizerChemistry #JOCasap using HFIP and low eq acid to remove PGs - shorter rxn times and cleaner profiles Oh you’ve got a PMB? Check! CBZ too! No hydrog needed #ChemSky
pubs.acs.org
Sulfonic Acid Promoted N-Boc-, N-Cbz-, and N-PMB Cleavage in 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) and Application to Acid Sensitive Substrates
We report on the mild, sulfonic acid promoted removal of N-Boc, N-Cbz, and N-PMB protecting groups in 1,1,1,3,3,3-hexafluoro-2-propanol (hexafluoroisopropanol; HFIP). According to this method, the typ...
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 16/05/2026
Pool season is here!!!
Nick shirtless relaxing on a sun chair next to a pool. He is extremely pale, but pay no mind to that
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Puff the Magic Hater @mskellymhayes.bsky.social · 24/04/2026
I interviewed @chanda.blacksky.app about her new book, The Edge of Space-Time. We discussed cosmic wonder, the mythology of genius, Deep Space Nine, and thinking beyond false narratives and manufactured inevitabilities. If your brain is stuck in the churn of bad news, you'll want to check this out.
organizingmythoughts.org
“We Don’t Know Most Things”: Chanda Prescod-Weinstein on Curiosity and the Cosmos
"We have to be curious and imaginative about how we might get out of this," says Chanda Prescod-Weinstein.
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Michelle Brann @michellebrann.bsky.social · 13/04/2026
I’m thrilled to share that I’ll be joining Bryn Mawr College as a tenure-track Assistant Professor of Chemistry in January 2027! I’m excited to teach Bryn Mawr students, build the Brann Astrochemistry Group, and continue mentoring and empowering women and gender-diverse students in STEM. 🚀🌟
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 10/04/2026
Was extremely happy to come home to this today! I've got my weekend reading locked in 😎 @chanda.blacksky.app
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Lisa Jarvis @lisamjarvis.bsky.social · 07/04/2026
The moon was still out when I awoke today & I stood in my living room grinning at it for awhile-I mean, can you believe that yesterday, the Artemis crew was RIGHT THERE? My latest @opinion.bloomberg.com is on the awe-inspiring mission as a crucial reminder of the value of investing in science. (🎁)
bloomberg.com
Artemis II’s Awe Reminds Us of Science’s Fragility and Importance
Three words uttered yesterday from Mission Control to Reid Wiseman, commander of Artemis II, perfectly capture the groundswell of emotion many of us have experienced over the last week as a team of as...
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 06/04/2026
The fact that all software switched to subscription rather than license model is a fucking crime. "Sign into revitty signals to use your ChemDraw." What if, and I know this is crazy, you just STICK TO THE ACTIVATION SYSTEM YOU'VE HAD SINCE THE BEGINNING. Seething rn.
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 02/04/2026
Request: PAA stain that doesn't go to complete dogshit in like a week on the bench even when protected from light
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 29/03/2026
Where are my fellow jazz band kids at? Is it just me or does Bruno Mars new song sound like Oye Como Va?
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Scott Bagley @bagphos.bsky.social · 25/03/2026
Today at #ACSSpring2026 we’ve got @ndchiappini.bsky.social in Academia 101 : Launching Your Lab talking about how to apply and interview for a faculty position and get ready to teach - stop by and hear from all our young faculty
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 24/03/2026
@chemfunman.bsky.social encounter!!! Love ACS!
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Adam Gurri @adamgurri.liberalcurrents.com · 09/02/2026
So uh Ring just up and said they've got a huge centralized private surveillance network they can leverage all at once huh
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Silicon Republic @siliconrepublic.bsky.social · 03/02/2026
Mozilla will allow Firefox users to entirely block current and future generative AI features on the browser after user feedback revealed many who wanted an AI-free browser experience.
siliconrepublic.com
New Mozilla Firefox version to allow AI features to be blocked
Mozilla will allow Firefox users to entirely block current and future generative AI features on the browser.
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 06/02/2026
HTE setups realizing they're being used for a Buchwald-Hartwig screen for the 1,286,712th time
A deeply haggard, starved and desperate Sarah Paulson faking a smile while eating a wholly underwhelming sandwich provided by her captor.  She is saying "This is good"
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 05/02/2026
It's honestly impressive how infuriating to use OneLan digital signage is. Forget user-friendliness, this is user antagonism
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 31/01/2026
A peek at my non-chemistry picks! Sociology of Science Fiction Deconstructing the Darkness of German Fairytales American Art History Modernism in Art and Music Italian Political History from Unification to Present
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Chanda Prescod-Weinstein 🌌 @chanda.blacksky.app · 30/01/2026
Please buy books that are coming out this year. Doesn’t have to be mine. But there is a stellar release calendar this year especially of Black writers and it would be a shame if one of the fascist victories was people not buying those books (from the indies that are in the fight with us). #BookSky
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Hockey Out of Context Loves Canada @nhloutofcontext.bsky.social · 21/01/2026
Andrei Vasilevskiy
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 28/01/2026
@chemrxiv.org Is there an RSS feed for the new host? I can't seem to find one via Feedly or the new site. (sorry for the double post, wasn't sure which platform was checked more often)
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Chanda Prescod-Weinstein 🌌 @chanda.blacksky.app · 28/01/2026
Black-body radiation is something we’ve understood for over a century, I teach it in my undergrad astrophysics classes, and it’s how the quantum revolution kicked off en.wikipedia.org/wiki/Black-b...
en.wikipedia.org
Black-body radiation - Wikipedia
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 28/01/2026
Potentially ignorant question: When a small molecule synthesis paper mentions using "GPC" for purification....what does that mean operationally? GPC immediately is like neon sign for POLYMERS and ANALYTICAL in my head. #chemsky
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Garth Marenghi's Catbus @catbus.phd · 02/01/2026
people keep voluntarily impaling themselves on the "you should all stop being mean to AI because it is BIG and STRONG and my FRIEND" stake, and I'm politely asking them to stop because it's embarrassing
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Bruno Dias @brunodias.dev · 27/12/2025
"Did you see what Mark Cuban posted? Oh did you see the clapb—" You shake yourself awake in the cold North Atlantic water. You are not online. It is July of 1858. You are a baleen whale, and you have changed your mind. The future most not come to pass. The telegraph cable must break.
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 24/12/2024
Cannot wait for my annual rewatch for Arthur Christmas. Complete with hot Santa Steve Claus voiced by Hugh Laurie and his elf assistant who is down extremely bad
Buff animated Santa in Christmas inspired fatigues and cinched waist. His goatee is cropped into the shape of a treeThree screenshots from Arthur Christmas of Steve Claus looking at his phone seeing texts from his elf assistant.

Three texts: "Great job today Sir."
"You looked great today Sir!"
"I'm still up. Just so you know."
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Distributed Denial of Secrets @ddosecrets.org · 23/12/2025
Updated with a pristine, HD copy courtesy of Leon Thomas @renegadecut.bsky.social Watch Inside CECOT now
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spooky scary renegade cut @renegadecut.com · 22/12/2025
60 minutes CECOT segment. Recorded through my browser. HD quality. Not phone. Spread it around. If you're press, it's yours. Go nuts. It's streaming on a Canadian website, but there is no telling for how long. www.filemail.com/d/wkcdttnacp...
filemail.com
Banned 60 Minutes CECOT Segment - Filemail
Get it while it's hot.
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 22/12/2025
Workshopping mnemonics for teaching the orgo 2 crowd 13cnmr shift regions. Current fave: "Keys to the car aren't there, Alfonso, you bastard!" For ketone/ald, other carbonyls, Arene/alkene, triple, alpha to F, O, N, S, boring #chemed
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Anthony Moser @anthonymoser.com · 19/12/2025
i just called the DC office of Sen Dick Durbin who is generally terrible and cannot be relied upon 202-224-2152 his staffer answered after the first ring and was unfamiliar with the bill. he has not taken a position on it. if you live in Illinois, please give him a call.
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Jake Berg @jacobsberg.bsky.social · 18/12/2025
Gift link, probably the funniest thing the Wall Street Journal has done this year.
wsj.com
We Let AI Run Our Office Vending Machine. It Lost Hundreds of Dollars.
An AI agent ran a snack operation in the WSJ newsroom. It gave away a free PlayStation, ordered a live fish—and taught us lessons about the future of AI.
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Micah @rincewind.run · 18/12/2025
this has exactly as much scientific basis as their antivax garbage and is somehow even more directly aimed at killing people fuck this absolute monster
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new world penis @jazzpomegranate.com · 18/12/2025
this really needs to be viewed as at the same level of science-rejection as getting rid of all the child vaccines
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gwen howerton @kissphoria.bsky.social · 17/12/2025
"I didn’t have the courage to come out until I was 21, and that means 21 years of pain, 21 years of unwavering homesickness that only went away when I was able to get the care that I needed. And my biggest regret in life is that I never had a childhood without that pain.”
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 13/12/2025
Question for the phys org people out there: Are there estimates of rel. electrophilicity of say an acylium ion on the Mayr scale? My searching has come up dry #ChemSky #AskChemSky
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Don Moynihan @donmoyn.bsky.social · 12/12/2025
Super interesting. Seems plausible to me that as people believe they are benefiting from collective action regulation (rent controls) they are more supportive of other public interest action. This is also Berlin, so the policy feedback processes may be different there than the US or elsewhere.
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 12/12/2025
Jarry for Skinner?! Kyle Dubas what on earth are you doing, mama? Do we need to trade places with the new mayor and give him a whirl as GM? The cosmic horrors of being a pens fan. #penguins
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Kevin M. Kruse @kevinmkruse.bsky.social · 07/12/2025
If they pretend they haven’t heard about the story of the day, end the interview right there. “I’m sorry, Senator, we wanted to get your perspective on this story, but it seems you’re not fully aware of what’s going on.”
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Chemjobber @chemjobber.bsky.social · 03/12/2025
I mean, we are 100% all the way back to the original debate with Derek's 2015 "The End of Synthesis" post | it was a "'synthesis requires expertise' versus 'let us democratize synthesis'" debate back then, and now it is "the computers/robots will help us de-artisanize synthesis" in 2025
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Scott Bagley @bagphos.bsky.social · 02/12/2025
And here it is – Annulative Editing – aka The Monster Mash. What a super collab #PfizerChemistry & @sarponggroup.bsky.social In 1 pot, activated pyrimidines with bis-nucleophiles like amino-pyrazoles & other small hets to deliver 6/5 hets and other useful products #MyFirstJACS #ChemSky #ChemChat
pubs.acs.org
Annulative Skeletal Diversification of Pyrimidines to Expanded Heteroaromatic Space
Single-atom skeletal editing has recently emerged as a powerful strategy for the direct diversification of the heterocyclic cores of various compounds. Yet, methods that enable monocycle-to-bicycle tr...
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 30/11/2025
Obsessed with this man ordering ketchup on Amazon at the coffee shop. He's had like 12 different varieties of ketchup up
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Nick Chiappini 🏳️‍🌈🧪 @ndchiappini.bsky.social · 25/11/2025
UNCW's Dept of Chem and Biochem is looking for four (4!) new members this cycle including: Asst Professor Analytical Chem Asst Professor Physical Chem Lecturer - Bio- and general Chem Lecturer - General Chem Our dept is a great place to work and Wilmington's a blast! #ChemSky #ChemJobs Links ⬇️
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