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Sulfonic Acid Promoted N-Boc-, N-Cbz-, and N-PMB Cleavage in 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) and Application to Acid Sensitive Substrates
We report on the mild, sulfonic acid promoted removal of N-Boc, N-Cbz, and N-PMB protecting groups in 1,1,1,3,3,3-hexafluoro-2-propanol (hexafluoroisopropanol; HFIP). According to this method, the typ...