iiinova — where your digital self keeps evolving

Nature Communications @natcomms.nature.com · 22/09/2026

Co-authors @merylhaas.bsky.social, @danielhurdiss.bsky.social from @utrechtvirology.bsky.social and others show that the norovirus NS3 protein forms an RNA-engaging molecular motor that may transport viral RNA during infection. #Virology #CryoEM dlvr.it/TVbP01

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Nature Communications @natcomms.nature.com · 15/09/2026

Tunneling nanotube-like connections shown to mediate bidirectional mitochondrial transfer between glioblastoma tumor cells and astrocytes in vitro, and between head and neck squamous cell carcinoma cells in vivo doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 09/09/2026

Contact #percolation controls motility and phenotype switching in heterogenous populations of #breastcancer cells doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 04/09/2026

Registration closes 10 September for the 5th Immuno-Metabolic Mechanisms of Atherosclerosis Conference in Playa del Carmen, Mexico. Join Senior Scientific Editor Laura Corradi at the upcoming meeting! @fusionconf.bsky.social Register here: bit.ly/4xGP11M #IMMA

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Nature Communications @natcomms.nature.com · 02/09/2026

Fanconi anemia pathway found to control MLL-rearranged #leukemia progression via blocking nonhomologous end joining-mediated genomic instability doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 02/09/2026

#α-ketoglutarate shown to stabilise a nuclear GLUD1-SNAIL complex, facilitating trans-endothelial migration during #cancer #metastasis doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 28/08/2026

ALLocate, a low-cost, AI-driven microscope plugin that enables self-driving microscopy for accurate and affordable leukaemia detection without whole-slide scanners #Cancer #CanSky #OncoSky #AI #Microscopy #Leukemia dlvr.it/TVCxJB

Illustration of the ALLocate hardware design, cost comparison, and end-to-end diagnostic workflow

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Nature Communications @natcomms.nature.com · 26/08/2026

The biology of jumbo phages (bacterial viruses with large DNA genomes) @vanbeljouw.bsky.social & @yuping-li.bsky.social highlight their diversity, evolutionary origins, lifecycles, host interactions & potential applications @biozentrum.unibas.ch dlvr.it/TVBJgn

Key stages of the lifecycle of jumbo phages

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Nature Communications @natcomms.nature.com · 25/08/2026

#Viruses & microbial ecology: The use of different methods can result in important differences in the recovery and quality of viral sequences detected in soil samples, which can affect ecological interpretations in soil viral community studies dlvr.it/TV9W2T

Methods used to study viral diversity in soil.

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Nature Communications @natcomms.nature.com · 25/08/2026

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Nature Communications @natcomms.nature.com · 24/08/2026

New perspective piece argues that #ArtificialIntelligence enables unified #EarthSystem models, bridging the gap between #weather #forecasting and #climate #prediction. @isp-uv-es.bsky.social @granthamlse.bsky.social www.nature.com/articles/s41...

Graphical summary of how artificial intelligence bridges weather and climate across key dimensions.

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Nature Communications @natcomms.nature.com · 21/08/2026

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Nature Communications @natcomms.nature.com · 21/08/2026

Zhang et al. explore genetic and molecular correlates of Peto's paradox by examining the evolutionary rates of human cancer-associated sites across 58 mammalian species #Cancer #CanSky #OncoSky #Evolution dlvr.it/TV6HxD

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Nature Communications @natcomms.nature.com · 20/08/2026

Segment Any Tumour 3D (SAT3D), a lightweight volumetric foundation model for robust and generalisable tumour segmentation across diverse medical imaging modalities, organs, and cohorts #cancer #CanSky #OncoSky #AI dlvr.it/TV63WG

Architecture of the Segment Any Tumour 3D foundation model for tumour segmentation

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Nature Communications @natcomms.nature.com · 20/08/2026

ALPaCA (Adapting Llama for Pathology Context Analysis), a general-purpose slide-level Large Vision Language Model for question answering in cancer computational pathology #cancer #CanSky #OncoSky #AI dlvr.it/TV5lH1

Scheme describing the ALPaCA model for cancer computational pathology

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Nature Communications @natcomms.nature.com · 19/08/2026

Bi et al. engineer #Salmonella to act as exogenous organelle-like devices that deliver PTEN and an MDM2 inhibitor to reactivate #p53 to #tumors, achieving durable tumor suppression and synergistic immune activation doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 11/08/2026

RPL22L1 shown to regulate translation of mRNAs related to DNA repair such as ATRX, and, consequently, RPL22L1 loss sensitizes cancer cells to chemotherapy doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 07/08/2026

Two recent papers, and the associated Comment piece, identify the cardiac protein Leiomodin 2 as an actin filament polymerase enabling growth from filament pointed ends dlvr.it/TTvYgs dlvr.it/TTvYgt dlvr.it/TTvYgw

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Nature Communications @natcomms.nature.com · 04/08/2026

NANS-mediated recruitment of USP7 stabilizes LATS2, driving tumor growth and resistance to endocrine therapy and #CDK4/6 inhibitors in #breastcancer doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 04/08/2026

#Obesity driven loss of gut microbial #GABA promotes metabolic changes that accelerate #colorectal cancer progression doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 27/07/2026

#EnvironmentalMicrobiology Co-migration of hundreds of microbial species over metres drives selection and promotes non-motile hitchhikers @susiegriggo.bsky.social @flinders.university.bsky.social #chemotaxis #metagenomics 🦠 dlvr.it/TTk6X2

Figure 1 from the article. A tube system allows for enumeration, identification and speed measurements of migrating microbes.

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Nature Communications @natcomms.nature.com · 24/07/2026

A phase 1/2 #clinicaltrial of #copanlisib in combination with the PD-1 inhibitor #nivolumab for patients with metastatic microsatellite stable #colorectalcancer doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 23/07/2026

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Nature Communications @natcomms.nature.com · 16/07/2026

Discovery that #Ras signaling leads to proteasomal degradation of EED, resulting in reduced H3K27me3 and activation of oncogenic transcriptional programs in squamous cell carcinoma #SCC doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 02/07/2026

Lung CD34+ fibroblasts found to promote the formation of a #premetastatic #niche via an upregulation of IFN-I response that drives cytotoxic NK and T-cell exhaustion doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 29/06/2026

#Replication stress-associated p21 expression marks proliferating juvenile #osteoblasts within a Hedgehog-dependent niche, while c-Myc activation and p53 loss cooperate to drive Hedgehog-independent #osteosarcoma formation doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 29/06/2026

#Pan-TEAD inhibitors, including a brain-penetrant inhibitor, decrease #YAP activity and suppress both peripheral and intracranial #tumor growth doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 20/06/2026

🦠 #Microbiology 🔬 New featured image on our homepage! dlvr.it/TT7dMW Read the #openaccess article: True cyst formation underlies persistence and drug tolerance in Tritrichomonas foetus dlvr.it/TT7dMX @intechchascomus.bsky.social #Parasitology

Colourized microscopy image of the protist Tritrichomonas foetus

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Nature Communications @natcomms.nature.com · 19/06/2026

🦠 #Microbiology 🔬 New featured image on our homepage! dlvr.it/TT6g9T Read the #openaccess article: True cyst formation underlies persistence and drug tolerance in Tritrichomonas foetus dlvr.it/TT6g9V @intechchascomus.bsky.social #Parasitology

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Nature Communications @natcomms.nature.com · 18/06/2026

An induced pluripotent stem cells-derived NF1-CDKN2A-PRC2-deficient model mimics malignant peripheral nerve sheath tumors, and can be used for drug combinations discovery doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 26/05/2026

#PublicHealth : Global travel hubs could be key in future pandemic surveillance efforts. Here, the authors show that traveler-focused genomic surveillance at key hubs can speed up detection of SARS-CoV-2 variants under resource constraints dlvr.it/TSkYyK

Study overview and early global spread of Omicron

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Nature Communications @natcomms.nature.com · 21/05/2026

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Nature Communications @natcomms.nature.com · 18/05/2026

#MicrobialEcology : Genome-centric metagenomics reveals electroactive syntrophs in a conductive particle-dependent consortium from coastal sediments @ameliarotaru.bsky.social @nordcee.bsky.social #methane #metagenomics #electromicrobiology dlvr.it/TSbqJY

Proposed electron-transfer network for syntrophic acetate oxidation using granular activated carbon.

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Nature Communications @natcomms.nature.com · 17/05/2026

#Symbiosis Magnetoreception in a freshwater ciliate arises from endosymbiosis The endosymbiotic bacteria produce magnetite crystals, allowing the protist to move efficiently in stratified waters dlvr.it/TSZp8Y

Visualization of the four types of endosymbiotic bacteria within the protist.

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Nature Communications @natcomms.nature.com · 15/05/2026

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Nature Communications @natcomms.nature.com · 13/05/2026

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Nature Communications @natcomms.nature.com · 13/05/2026

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Nature Communications @natcomms.nature.com · 11/05/2026

#CRISPR base-editor #screens predict shared and drug-specific MEN1 #resistance mutations across five clinical menin inhibitors doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 11/05/2026

Discovery that endocrine therapy upregulates Rac1 signalling component P-Rex1, and inhibition of Rac1 reduces tumor growth in refractory breast cancer models doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 21/04/2026

Finding that ZEB1-mediated repression of ELMO3 creates a synthetic-lethal dependence on ELMO2, and that inhibiting ELMO2 selectively kill mesenchymal-like cells and EGFR TKIs–resistant cancer cells doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 30/03/2026

FOXA1 loss in mice shown to drive basal-squamous de-differentiation and to remodel the tumor microenvironment in prostate cancer doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 27/03/2026

Announcing Nature Progress Oncology! An open-access journal in the new Nature Progress series, publishing significant advances in cancer research, from cell biology and immunology, therapeutics, clinical research, and epidemiology nature.com/natprogoncology

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Nature Communications @natcomms.nature.com · 26/03/2026

Announcing Nature Progress Brain Health! A new open-access journal bringing together timely research across the full landscape of brain health, including preclinical and translational neuroscience, neurology, and neuropsychiatry nature.com/natprogbrainhealth

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Nature Communications @natcomms.nature.com · 09/03/2026

Intermediate #PRRX1 levels primes #cancer cell for high invasion and metastatic fitness, whereas extreme expression leads to cell cycle inhibition and #dormancy doi.org/10.1038/s414... @ruljcz.bsky.social @nietoangela.bsky.social

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Nature Communications @natcomms.nature.com · 09/03/2026

#LRRK2 inhibitors found to enhance viral infection and oncolysis by oncolytic herpes simplex virus #therapy in #glioblastoma doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 09/03/2026

eIF6 identified as a regulator of #SCLC small cell lung carcinoma #plasticity, driving non-neuroendocrine transdifferentiation via regulation of the CD104/FAK complex doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 09/03/2026

Discovery that #obesity induces the expression of the peptide hormone cholecystokinin (CCK) in #β-cells, affecting the peri-islet acinar cells and promoting islet-proximal #tumor formation @muzumdarlab.bsky.social @krishnaswamylab.bsky.social doi.org/10.1038/s414...

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Nature Communications @natcomms.nature.com · 09/03/2026

RIPK1-driven #necroptosis in both tumor and stromal compartments found to be essential for effective immunogenic cell death-based therapy and immune checkpoint @meierlabicr.bsky.social doi.org/10.1038/s414...

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