Essential roles of epicardium in coronary lymphangiogenesis unrelated to coronary blood vasculature development. VEGFD cooperates with VEGFC but only in females. Ester de la Cruz and Vanessa Cadenas in my lab + collaboration with Guillermo Oliver made it possible.
www.embopress.org/doi/full/10....
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Epicardial VEGFC/D signaling is essential for coronary lymphangiogenesis | EMBO reports
imageimageSignals from the epicardium are essential for fetal coronary lymphangiogenesis. VEGFC and VEGFD produced by the epicardium target the subepicardial space, where they are essential for the formation of the lymphatic vasculature in a dose-...