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Michael Seidl

@mfseidl.bsky.social
1.5K followers 524 following 38 posts

Associate Professor, Microbial Genome Evolution, Utrecht University, the Netherlands

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Reposted by Michael Seidl
Ciaran Kelly @ciarankelly.bsky.social · 08/09/2026
Our new preprint is out! 🍄 Decoupled evolution of antimicrobial repertoires in lichen-forming fungi We compared many lichen-forming fungal genomes to ask how different photobiont associations relate to their antimicrobial repertoires.
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Cecile Lorrain @ccilelorrain.bsky.social · 31/08/2026
Now accepted: Haplotype-phased assemblies of the two poplar rust fungi species: Melampsora larici-populina and Melampsora allii-populina academic.oup.com/g3journal/ar...
academic.oup.com
Haplotype-phased assemblies of the two poplar rust fungi species: Melampsora larici-populina and Melampsora allii-populina
Abstract. Dikaryotic rust fungi maintain two distinct haploid nuclei for most of their life cycle, making their large, repeat-rich genomes difficult to ass
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Remco Stam @rstam.bsky.social · 30/08/2026
New preprint online! We sequenced several hundred Zymoseptoria isolates from different fields through a field epidemic to ask what really drives short-term evolution. Fungicide selection or seasonal epidemic progression? www.biorxiv.org/content/10.6...
biorxiv.org
Standing genetic variation buffers field populations of Zymoseptoria tritici against seasonal and fungicide selection
### Competing Interest Statement AT was funded by BASF under a formal scientific collaboration agreement. BASF did not exert control over the data collection, analysis, or interpretation of results. ...
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PLOS Biology @plosbiology.org · 27/08/2026
Giant viruses are known across eukaryotes. This study by @hyphaltip.bsky.social &co identifies Mycodnaviridae, a global giant #virus family that persistently infect zoosporic #fungi, providing a promising model for studying #giantVirus infection in eukaryotes. 🧪 #AcademicSky plos.io/3Sq4ioL
Allomyces javanicus California 12
Sexual structures of the fungus Allomyces javanicus California 12, which is persistently infected with a giant virus. Image credit Timothy James.

I confirm that the images provided can publish under the Creative Commons Attribution
License.
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The Sainsbury Laboratory @thesainsburylab.bsky.social · 13/08/2026
New Publication: Tangerine: A new family of Starships from lichen-forming fungi (2026) www.tsl.ac.uk/publications...
tsl.ac.uk
Tangerine: A new family of Starships from lichen-forming fungi
Lichens are symbiotic associations between filamentous fungi and photosynthetic micro-organisms, such as green algae and/or cyanobacteria, that result in a single anatomically complex structure that…
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Bas E. Dutilh @bedutilh.bsky.social · 21/08/2026
Join us and become part of PhageOrder: study the evolution of phage genetic modules!
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PM Delaux @pierremarcdelaux.bsky.social · 18/08/2026
Finally online! It took ut 9 yars from formulating the hypothesis to actually finalizing the last experiments... but there it is!
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 13/08/2026
Data-driven inference of local behavioural rules predicts emergent properties of Phytophthora zoospore dispersal www.biorxiv.org/content/10.64898/20…
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Universität zu Köln @unicologne.bsky.social · 07/08/2026
🫒Warum der Olivenbaum die Blätter verliert Erstmalig ist es einem Forschungsteam ‪@teamthomma.bsky.social‬ @ceplas.bsky.social gelungen, Einblicke in die genetischen Grundlagen der durch den Schädlingspilz Verticillium dahliae verursachten „Entlaubung“ zu bekommen ➡️https://uni.koeln/RC5HX
Olivenhain mit vereinzelten Bäumen auf grüner Wiese unter bewölktem Himmel, gelbe Blumen im Gras verteilt.
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Toby Baril @tobybarilbio.bsky.social · 12/08/2026
Thrilled to share that I'll be starting my lab at the Swedish Museum of Natural History in Stockholm as a DDLS Fellow in November! 🧑‍🔬🧬🎉 Of course, we will be delving into all things mobile DNA & evolution, as well as developing AI approaches for biodiversity genomics #newPI #TEsky #TEworldwide
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Gulnara Tagirdzhanova @metalichen.bsky.social · 11/08/2026
Our study on giant transposons Starship 🚀🧬 in the genome of the lichen fungus Xanthoria is now out in @pnas.org! What did we find out about Starships in #lichen fungi? 👇Updated thread below 🖥️ 🧪 🦠 🧫 #SymbioSky 1/6 www.pnas.org/doi/10.1073/...
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Universität zu Köln @unicologne.bsky.social · 07/08/2026
🫒Why the olive tree loses its leaves For the first time, a research team led by @teamthomma.bsky.social @ceplas.bsky.socialhas succeeded in gaining insights into the genetic basis of the ‘defoliation’ caused by the pathogenic fungus Verticillium dahliae. Read more➡️https://uni.koeln/JJ7F2
Olivenhain mit vereinzelten Bäumen auf grüner Wiese unter bewölktem Himmel, gelbe Blumen im Gras verteilt.
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Genome Biology and Evolution @genomebiolevol.bsky.social · 04/08/2026
Nazir & @bramvandijk.bsky.social demonstrate how phage lifecycle dynamics and spatial heterogeneity drive mobile genetic element–gene associations, providing new insights into the evolution of phage-encoded virulence. 🔗 doi.org/10.1093/gbe/evag181 #societyjournal #virus
doi.org
Viral Lifecycle Dynamics and Spatial Structure Explain Why Accessory Genes Are Associated With Temperate Phages
Abstract. Genes encoding for virulence factors are frequently found on prophages, yet the evolutionary forces driving this association remain unclear. The
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Marnix Medema @marnixmedema.bsky.social · 04/08/2026
New postdoc opportunity in our team! Topic is computational analysis of (meta)genomic data to study evolution of plant-microbiome interactions. Part of the AEGIS consortium (aegisearth.bio/en). Apply here: www.wur.nl/en/vacancy/p... Please RT!
wur.nl
Postdoc on computational (meta)genomic analysis
Climate change is one of the greatest challenges for global food security, requiring new approaches to understand and harness the natural diversity that enables plants and their associated microbiomes...
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Forschungszentrum Borstel, Leibniz Lungenzentrum @fzborstel.bsky.social · 20/07/2026
Neue Forschungsgruppe stärkt die funktionelle Mikrobiomforschung am @fzborstel.bsky.social: Prof. Dr. Amelia Barber übernimmt die W3-Professur für „Funktionelle Mikrobiomforschung chronischer Lungenerkrankungen“ und baut am FZB eine neue Forschungsgruppe auf: fz-borstel.de/de/aktuelles...
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Björn Usadel @usadellab.bsky.social · 23/07/2026
Join my group at @fz_juelich within the @ceplas.bsky.social excellence cluster. #PlantJobs We’re looking for a postdoc/senior scientist in plant single-cell and spatial transcriptomics recruiting.fz-juelich.de/jobposting/8...
recruiting.fz-juelich.de
Postdoctoral Researcher / Senior Scientist in the field of plant single-cell and spatial transcriptomics
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Gabriel Schaaf @gabrielschaaf.bsky.social · 22/07/2026
Please share! 🌱🤖 Permanent W2 Professorship in crop & plant sciences @ PhenoRob, University of Bonn. Especially encouraged: crop genome engineering, sustainable pest control, or sustainable disease control. Expertise in one area is enough. Apply by Sept. 30, 2026. www.uni-bonn.de/en/universit...
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Cedric Feschotte @cedricfeschotte.bsky.social · 22/07/2026
Super proud and excited about this work, led masterfully by Peiwei Chen! A fun and fruitful collaboration with department colleagues Andy Clark & Alexei Aravin. After 30 yrs of studying transposons, this is one of the very first times I see them jump in real time in their natural host! Hurrah! 🥳
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Ursula Oggenfuss @oggenfussursula.bsky.social · 20/07/2026
I am happy to share that my NWO Veni project was awarded 🍄🧬🔻! In this project, I will study how transposons shape genome folding, evolution, and adaptation in a fungal salamander pathogen. I am incredibly thankful for all the support and look forward to this next chapter #fungi #transposons #TEsky
A sketch of two salamander species, with a zoomed in picture of a fungal fruit body releasing spores, leading to a small stretch of DNA which ends in a folded chromosome with many green triangles indicating transposon insertions
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David Cooke @llewelyn68.bsky.social · 20/07/2026
Status of #Phytophthora infestans populations in Europe updated. Helping late blight IPM on potato crops. Sunshine may be a good fungicide but I imagine many thirsty crops about. @hutton.ac.uk EuroBlight final data release, 2025 share.google/PhwBZllqrWdE...
share.google
EuroBlight final data release, 2025
EuroBlight announce the final results of 2025 monitoring – despite the low blight pressure 2025 season over 1700 samples from 27 countries across Europe were genotyped.
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Team Thomma @teamthomma.bsky.social · 17/07/2026
📣 Sunny ☀️ celebration 🎉🥳: Chen-Yu Kuan succesfully defended her PhD thesis entitled "Genome evolution in the plant-pathogenic fungus Verticillium dahliae in the absence of apparent sexual reproduction" @unicologne.bsky.social 🥳
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Ralph Hückelhoven @huckelhovenr.bsky.social · 15/07/2026
A tomato MIK2‐clade receptor is involved in the perception of a Fusarium‐derived elicitor - Maroschek - New Phytologist - Wiley Online Library nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com
A tomato <fc>MIK2</fc>‐clade receptor is involved in the perception of a <fi>Fusarium</fi>‐derived elicitor
Fusarium elicitor responsivness and MIK2-clade proteins are conserved across plant families.
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Sergio Alías Segura @seraliseg.bsky.social · 14/07/2026
Back in Madrid after 3 months at @utrechtuniversity.bsky.social! I recently wrapped up a research stay at @binfutrecht.bsky.social working on cereal metagenomics for my PhD thesis 🧬 Big thanks to @mfseidl.bsky.social and the TBB team, and to @femsmicro.org for the Research and Training Grant!
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Adam Bentham @adamrbentham.bsky.social · 13/07/2026
Excited to see our new preprint on bioRxiv! 🌱🤖 We used AI protein design (RFdiffusion + ProteinMPNN) to build brand-new sensor domains from scratch and installed them in a rice NLR immune receptor engineering recognition of a Fusarium effector FoSSP17
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Sophien Kamoun @kamounlab.bsky.social · 06/07/2026
Martijn Rep on the effectors of Fusarium oxysporum, a pathogen of many plants 🍉 🍅 🌴 🍌 🧅
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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 06/07/2026
Shoutout to the speakers for their fantastic talks today: Petros kicked the day off, followed by Melanie Mendel, @kamounlab.bsky.social, Francine Govers and Martijn Rep
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Theoretical Biology & Bioinformatics @ UU @binfutrecht.bsky.social · 06/07/2026
Today we're enjoying a wonderful symposium hosted by Petros Skiadas & @mfseidl.bsky.social, as a prelude for Petros's PhD defence. Lots to learn about oomycetes and plant pathogenesis, immunity and effector biology! @ubc-uu.bsky.social @utrechtuniversity.bsky.social
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PlantEvolution 🌱🌾 @plantevolution.bsky.social · 06/07/2026
Have a favorite European colleague who should be recognized for their work in non-medical biotechnology? Pls nominate them for the Novo Nordisk Foundation Prize for Biotechnology. (Prior awardees at novonordiskfoundationprize.com/awardees). Thank you! novonordiskfoundationprize.com/nominate-bio...
novonordiskfoundationprize.com
The Novo Nordisk Foundation Prize
Our prizes are awarded to researchers who have contributed to scientific breakthroughs or in other ways distinguished themselves within natural or medical science.
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Xander Zuijdgeest @xanderzuijdgeest.bsky.social · 01/07/2026
My PhD thesis has been submitted and reviewed, and my PhD defence is on the horizon! But today I start my next chapter as a postdoc in the Molecular Plant Immunity lab led by @clemmar.bsky.social at @ipbhalle.bsky.social! Here I will continue to dive into the form & function of plant NLRs 🌱
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Michael Sieber @michaelsieber.bsky.social · 01/07/2026
Have ideas for your own, independent research program in Theoretical Biology? Then come and join us as a Group Leader at the @mpi-evolbio.bsky.social in Plön, Germany!
mpg.de
Group Leader in Theoretical Biology (m/f/d)
Experience in Theoretical Biology, Applied Mathematics, Theoretical Physics
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EMBO @embo.org · 30/06/2026
Welcome and congratulations to the 60 new members and 11 associate members who have been elected to the EMBO Membership! They join a community of more than 2,200 leading scientists. 🧪 www.embo.org/press-releases/seventy… #EMBOMembers2026
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Amelia Barber @ameliabarberphd.bsky.social · 30/06/2026
Finally, I am recruiting a bioinformatic engineer/technician, a lab technician, and a postdoc to help establish the group at @fzborstel.bsky.social (~20km outside Hamburg). More info at: fz-borstel.de/en/education....
fz-borstel.de
Jobs - Forschungszentrum Borstel, Leibniz Lungenzentrum
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Amelia Barber @ameliabarberphd.bsky.social · 30/06/2026
Exciting news! After a wonderful four years at @uni-jena.de, I'm excited to announce the next chapter as a group leader at @fzborstel.bsky.social and professor at @uni-kiel.de.
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Clément Goubert @clementgoubert.bsky.social · 25/06/2026
Major development in the #Transposon world! Repbase is joining the Dfam project and becomes open-access! link.springer.com/article/10.1...
link.springer.com
Unifying Repbase and Dfam: a new open foundation for transposable element research - Mobile DNA
Repbase and Dfam, the two foundational resources for transposable element annotation, are being unified into a single, fully open access framework, with Repbase released under CC-0 and its core curati...
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Nature Microbiology @natmicrobiol.nature.com · 23/06/2026
Out Now! Modelling the role of the microbiome in antimicrobial resistance across scales #MicroSky
go.nature.com
Modelling the role of the microbiome in antimicrobial resistance across scales
Nature Microbiology, Published online: 22 June 2026; doi:10.1038/s41564-026-02390-8The microbiome plays a significant yet underexplored role in antimicrobial resistance by influencing ecological and evolutionary processes. This Perspective proposes a framework to integrate microbiome–AMR interactions into predictive models while highlighting key mechanisms and data gaps to improve resistance understanding and interventions.
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David Giron Villalobos @dagivi.bsky.social · 22/06/2026
1/4. Excited to share the first preprint from my PhD at @binfutrecht.bsky.social and @uti-revisited.bsky.social 🐥. In this work, we explored the urinary tract microbiome composition (urobiome) by combining data from multiple metagenomic sequencing studies 💛🦠. www.biorxiv.org/content/10.6...
biorxiv.org
Cross-study metagenomics analysis reveals distinct microbial signatures of urinary tract infections
Background Urinary tract infections (UTIs) represent a major public health concern, increasingly complicated by rising antibiotic resistance, diminishing treatment efficacy, and increasing prevalence ...
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Team Thomma @teamthomma.bsky.social · 22/06/2026
First 👀 on @biorxivpreprint.bsky.social, now online in @natureportfolio.nature.com Nature Communications: A structurally unique effector shared between vascular wilt fungi drives cotton and olive defoliation #Verticillium #Fusarium @lfaino.bsky.social www.nature.com/articles/s41...
nature.com
A structurally unique effector shared between vascular wilt fungi drives cotton and olive defoliation - Nature Communications
Here the authors report a pair of identical effector genes in different fungal pathogens that cause vascular wilt diseases to cause defoliation in crops. Removing these genes stops disease, and mobile...
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Sophien Kamoun @kamounlab.bsky.social · 19/06/2026
Join us in Utrecht 🇳🇱 SYMPOSIUM & PUBLIC PhD DEFENCE SMALL CHANGES FUEL A RAPIDLY EVOLVING THREAT The genomic basis of resistance breaking in spinach downy mildew Petros Skiadas @pskiadas docs.google.com/forms/d/e/1F...
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Thorsten Langner @thorstenlangner.bsky.social · 08/06/2026
‼️Job alert📢🚨 We are recruiting a Junior Group Leader (f) in Protein Science at Martin Luther University Halle-Wittenberg, jointly hosted by the Institute of Biochemistry and Biotechnology and our Collaborative Research Centre CRC 1664 "Plant Proteoform Diversity – SNP2Prot."
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The Tattooed Professor @schwessinger.bsky.social · 16/06/2026
Super happy we are doing it again our joint Nanopore Sequencing Workshop or jamboree 2026 The Centre for Crop and Disease Management, in partnership with ANU, is hosting a 3-day intensive Nanopore Sequencing Workshop from 17–19 November 2026 at Curtin University. www.ccdm.com.au/nanopore-seq...
ccdm.com.au
CCDM Nanopore Sequencing Workshop 2026 - CCDM
About the Workshop Nanopore sequencing continues to transform how we investigate biological systems. Since its early adoption for biosecurity and pathogen surveillance, the technology has matured rapi...
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Thomas Badet @tbadet.bsky.social · 11/06/2026
Nearly a year after our symposium on Repeat-Induced Point (RIP) mutations, I’m happy to share the fruit of some of our discussions. The fungal RIP hypermutator mechanism has deep eukaryotic roots www.sciencedirect.com/science/arti... We hope to spark interest in this underappreciated mechanism.
Evolution of major eukaryotic genome defense systems.
The figure is organized along two axes representing core mechanistic features (homology recognition, small interfering RNA, and
heterochromatin assembly) and their lineage-specific elaborations. We hypothesize that a recombination-independent DNA
homology recognition system present in the eukaryotic common ancestor facilitated the emergence of both heterochromatin
assembly and small RNA-based repeat silencing. From this conserved ancestral core, lineage-specific gene neofunctionalizations
gave rise to distinct defense pathways: the RdDM pathway in plants; the piRNA and KRAB–ZFP pathways in vertebrates; and the
repeat-induced point mutation (RIP), methylation induced premeiotically (MIP), MSUD, and tandem repeat-induced sexual silencing
(TRISS) systems in filamentous ascomycete fungi. Question marks indicate steps for which the molecular mechanisms remain
unknown.
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Toni Gabaldón @tonigabaldon.bsky.social · 10/06/2026
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...
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Team Thomma @teamthomma.bsky.social · 30/05/2026
📣Last week another @biorxivpreprint.bsky.social dropped: "A fungal pathogen effector that shapes host plant microbiota kills bacteria through lipoteichoic acid binding and membrane disruption" a joint effort by @nicksnelders.bsky.social & @gabriellapetti.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
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Michael Seidl @mfseidl.bsky.social · 30/04/2026
Congratulations @mesny.bsky.social @teamthomma.bsky.social fantastic work!
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Ralph Hückelhoven @huckelhovenr.bsky.social · 19/03/2026
www.uni-hannover.de/en/jobs/id/8...
uni-hannover.de
University Professorship in Molecular Phytopathology – Leibniz University Hannover
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Christian Landry @christianlandry.bsky.social · 24/03/2026
Nice surprise this morning! A Dispatch on our paper on paralog interference now out in Current Biology! By Krishna Swamy and Jun-Yi Leu. www.cell.com/current-biol...
cell.com
Evolution: Paralog interference stabilizes gene duplicates
Gene duplicates are traditionally viewed as evolutionarily unstable, as one copy can freely accumulate deleterious mutations and be lost. A new study reveals that paralog interference exposes certain ...
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Bram van Dijk 🏳️‍🌈 @bramvandijk.bsky.social · 23/03/2026
Phd Position alert 🚨 Join our project ASTRAfun (Adaptation and Starship Traffic in Root-Associated fungi), in which we will use computational models to unveil the hidden dynamics of fungal evolution. It’s not going to be just regular fun. It’s going to ASTRAfun. 🤓 www.uu.nl/en/organisat...
uu.nl
PhD Position in Computational Modelling of Fungal Evolution
How do giant mobile elements called ‘Starships’ reshape fungal plant pathogens? Help us computationally model their spread and impact in nature and agriculture!
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Bram van Dijk 🏳️‍🌈 @bramvandijk.bsky.social · 25/02/2026
In case you missed it: our review titled "Spatial structure: shaping the ecology and evolution of microbial communities" is out! 🚨 Let me hit you with some highlights on why spatial structure matters. (and why you should care!) Sharing is appreciated 🙏 🧵👇 doi.org/10.1093/fems...
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Team Thomma @teamthomma.bsky.social · 14/02/2026
📣 Our latest story just dropped on bioRxiv:: A structurally unique effector shared between Verticillium dahliae and Fusarium oxysporum is involved in cotton defoliation and virulence on other hosts www.biorxiv.org/content/10.6... 🧵
biorxiv.org
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