This cohort study uses the data from all adults aged 18 to 59 years living in France on November 1, 2021, to evaluate whether there is an association of receipt of an mRNA COVID-19 vaccine with long-t...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

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In this clinical trial, a single dose of intravenous ketamine delivered during surgical anesthesia had no greater effect than placebo in acutely reducing the severity of depressive symptoms in adults ...

WASHINGTON—Addressing the ongoing outbreak in Texas that has infected at least 124 state residents and killed one child, Health and Human Services Secretary Robert F. Kennedy Jr. vowed Thursday to mak...

Nature - Opponent control of reinforcement by striatal dopamine and serotonin

Anxiety elicits various physiological responses, including changes in respiratory rate and neuronal activity within specific brain regions such as the medial prefrontal cortex (mPFC). Previous researc...

Stress induces aversive memory overgeneralization, a hallmark of many psychiatric disorders. Memories are encoded by a sparse ensemble of neurons acti…

The association between connectivity of the hypothalamus and stress is not well understood. Here, the authors show connectivity between hypothalamic nuclei and other subcortical structures is predicti...

Precision functional mapping shows that the frontostriatal salience network occupies nearly twice as much of the cortex in people with depression, and this was unaffected by mood changes and detected ...

This study shows that every individual has a unique pattern of functional connections between brain regions. This functional connectivity profile acts as a ‘fingerprint’ that can accurately identify t...