iiinova — where your digital self keeps evolving

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The Space Pope @popecrocodylus.bsky.social · 18/09/2026

Not bad, but this one is my favorite:

@prettyliltakemachine

Welcome new students. My name is Charles Xavier. The world around you will judge people like us for our differences, but at this school we seek to teach you to harness - who thought that. I do not look like Mr. Clean's gay brother. Who thought that."

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Tim Clancy @viewfromarchstreet.com · 18/09/2026

The road to AI safety runs through cybersecurity.

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Stand Up for Science! @standupforscience.net · 28/05/2026

BREAKING: New proposed OMB regulation, applying to all federal grants, requiring grant reviews by senior political appointees and re-emphasizes that "peer review remains advisory and does not replace agency discretion". #standupforscience public-inspection.federalregister.gov/2026-10817.pdf

public-inspection.federalregister.gov

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Matt Might @matt.might.net · 28/05/2026

Me to Claude Code: I want you to … Claude Code: But first, log in again.

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Matt Might @matt.might.net · 14/05/2026

My favorite zoom error message.

“Meeting not existed. (3,001)” is an unusual error message given by zoom.

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BWJones @bwjones.bsky.social · 17/04/2026

The Yak-52 first flew in 1976. These Ukrainian pilots and crew blasting drone out of the sky from open cockpits is one of the most bad-assed things I’ve ever seen.

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Edward Nirenberg @enirenberg.bsky.social · 07/03/2026

I am just now catching up on the fact that the FDA was demanding Uniqure do sham brain surgeries (from what I can tell, comprising simulated burr holes and 10-12 hours of anesthesia) in their placebo arm for their Huntington's therapeutic, and I'm absolutely floored that this was a serious demand.

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Matt Might @matt.might.net · 27/10/2025

Are you finished with the proposal?

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Jeremy Berg @jeremymberg.bsky.social · 20/10/2025

My quote of the day Courage is the most important of all the virtues, because without courage you can't practice any other virtue consistently. You can practice any virtue erratically, but nothing consistently without courage. Maya Angelou

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Matt Might @matt.might.net · 20/10/2025

The expression “making time” is strange. Time cannot be manufactured. It can only taken from one thing and given to other.

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Erin Green @erinrgreen.bsky.social · 04/10/2025

Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

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Matt Might @matt.might.net · 03/10/2025

Ok. Didn’t know that was a thing. But I don’t judge.

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Emily J @emexastris.bsky.social · 07/07/2025

Are you from one of these states? Then we need your help to save American science! The Senate Appropriations Committee will be marking up the President's Budget Request for science on Wednesday. People have been saying the proposed cuts "decimated" US science, but that's wrong: they are apocalyptic

A map of the US with the states the republican senators are from marked in red and states the democratic senators are from marked in blue:
Senator Susan Collins (Republican - Maine)
Senator Mitch McConnell(Republican - Kentucky)
Senator Lisa Murkowski(Republican - Alaska)
Senator Lindsey Graham(Republican - South Carolina)
Senator Jerry Moran(Republican - Kansas)
Senator John Hoeven(Republican - North Dakota)
Senator John Boozman(Republican - Arkansas)
Senator Shelley Moore Capito(Republican - West Virginia)
Senator John Kennedy(Republican - Louisiana)
Senator Cindy Hyde-Smith(Republican - Mississippi)
Senator Bill Hagerty(Republican - Tennessee)
Senator Katie Britt(Republican - Alabama)
Senator Markwayne Mullin(Republican - Oklahoma)
Senator Deb Fischer(Republican - Nebraska)
Senator Mike Rounds(Republican - South Dakota)
Patty Murray(Democrat - Washington)
Richard Durbin(Democrat - Illinois)
Jack Reed(Democrat - Rhode Island)
Jeanne Shaheen(Democrat - New Hampshire)
Jeff Merkley(Democrat - Oregon)
Christopher Coons(Democrat - Delaware)
Brian Schatz(Democrat - Hawaii)
Tammy Baldwin(Democrat - Wisconsin)
Chris Murphy(Democrat - Connecticut)
Chris Van Hollen(Democrat - Maryland)
Martin Heinrich(Democrat - New Mexico)
Gary Peters(Democrat - Michigan)
Kirsten Gillibrand(Democrat - New York)
Jon Ossoff(Democrat - Georgia)

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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 07/06/2025

Today is the last day to submit public comments on Schedule F, which is essentially designed to politicize the Civil Service. Here is the letter that I just submitted:

7 June 2025

Re: O+ice of Personnel Management

• 5 CFR Parts 210, 212, 213, 302, 432, 451, and 752

• Docket ID: OPM-2025-0004

• RIN 3206-AO80

• https://www.federalregister.gov/documents/2025/05/23/2025-09356/improvingperformance-accountability-and-responsiveness-in-the-civil-service

To Whom It May Concern:

I strongly oppose renewal of Schedule F. Civil service protections exist precisely for the reason that faithful execution of federal policy requires production of unbiased ﬁndings of fact and application of expertise. In a multitude of cases this is statutorily mandated. Civil service protections help to ensure that the executive branch does not itself become an unconstitutional engine of legislation through political hiring, promotion, and ﬁring decisions. At-will employees are inevitably subject to real or perceived pressures from current or incoming administrations, and will act accordingly, rather than on behalf of the American people and the statutory requirements imposed by Congress. This will distort and even invert the allocation and separation of powers deﬁned in Articles I and II of the Constitution.

Insulation from short-term political whims is of special importance when the executive is charged with interpreting and executing Congress’s intent on technical issues. These include but are not limited to assessment of applications and proposals for grants and contracts, in areas touching or centered on science, engineering, technology, and medicine. Congress has made clear that merit assessment by domain experts is core to the integrity, e+iciency, and excellence of the American scientiﬁc and medical enterprise.

This is true in agencies that include but are not limited to: the National Institutes of Health; the National Science Foundation; the National Aeronautics and Space Administration; The Environmental Protection Agency; the National Park Service; the National Oceanographic and Atmospheric Administration and National Weather Service; the National Forest Service; the Bureau of Land Management; the National Transportation Safety Board; and many others.

Over many decades, Congress has made clear time and again that the national interest requires the investiture of long-term planning and expertise, over timespans extending beyond a single presidential administration or political party. Continuity of expertise and institutional memory are statutorily mandated and not negotiable.

Schedule F makes a mockery of these requirements, and will inevitably result in the loss of this essential impartiality and continuity. It also opens the door to unethical patronage and other abuses. Thus, the end results of Schedule F will damage the Constitutional separation of powers and harm the national interest. Schedule F will lead to the loss of this continuity and impartiality, threatening the nation’s economic power, health, defense, and scientiﬁc leadership, and ceding the global lead in these areas to competitor states that will continue to emphasize long-term planning and technical excellence.

Schedule F is harmful to the national interest in the ways outlined above and others. Schedule F must be eliminated, not renewed.

Sincerely, and with all due respect,

Alexey Merz, Ph.D.

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BWJones @bwjones.bsky.social · 06/06/2025

If universities do not unite on this, we will all fall. The entire country will suffer. They will not stop at Harvard and Columbia. They are coming for ALL of higher education. Every single center of higher education will be targeted. This is what authoritarians do. Again, and again, and again.

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Carl T. Bergstrom @carlbergstrom.com · 16/05/2025

From hundreds of terminated grants in biomedicine to selective prosecutions to organizational overhauls at the nation's science funding agencies, today's news reports salvo after salvo from a Republican administration dead set on destroying higher education—and with it, US leadership in technology.

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Molly Franke @mollyfranke.bsky.social · 15/05/2025

All 4 of my NIH research grants are terminated. These were grants on MDR-TB treatment & strategies for supporting adolescents living w/ HIV. This is a massive waste of resources. I am heartbroken for my Harvard team, my partners in Peru, the next generation of scientists & our country. Shame.

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Brad Heath @bradheath.bsky.social · 16/05/2025

FROM @reuters.com: The Trump administration has said addressing autism is one of its top health priorities. Records show it has also halted about a quarter of NIH's research funding related to autism. www.reuters.com/business/hea...

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Lynn Jolicoeur @lynnjolicoeur.bsky.social · 16/05/2025

"I'm still in shock. I know that there have been political issues around Harvard in recent weeks, but antibiotic resistance isn't one of them." My conversation with Harvard microbiologist @baym.lol, one of many researchers there who just lost millions in fed. grants. www.wbur.org/news/2025/05...

wbur.org

Antibiotic research at Harvard lab threatened by federal funding cuts

Microbiologist Michael Baym studies antibiotic resistance at Harvard Medical School. He lost millions in federal funding this week.

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Jay Rosen @jayrosen.bsky.social · 17/05/2025

"The future of biomedical research [amounts to] a race to see whether the biomedical research community can mobilize politically, access that vast but latent political power, before the White House can do enough sustained damage to make the whole question moot." talkingpointsmemo.com/edblog/a-pat...

talkingpointsmemo.com

A Path Forward to Save American Bio-Medical Research

Over the past four months, I’ve spoken to dozens of biomedical researchers...

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Matt Might @matt.might.net · 15/05/2025

A scientific Boston massacre.

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Reposted by Matt Might

NEJM.org @nejm.org · 15/05/2025

A lipid nanoparticle–delivered base-editing therapy was custom designed for an infant with a ureacycle disorder. The affected infant was treated at approximately 7 and 8 months of age. Read the Brief Report: nej.md/42XF03F #ASGCT2025 #MedSky @asgct.bsky.social

nej.md

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease | NEJM

Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality ...

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Stand Up for Science! @standupforscience.net · 14/05/2025

At the end of this summer, the future of U.S. science and research will be decided. From weather alerts to cancer breakthroughs, science shapes every part of our lives. We need everyone in this fight. The Summer Fight for Science starts now. Are you in? The fight starts here: bit.ly/4ddiuqU

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Michael Baym @baym.lol · 14/05/2025

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

A screenshot of the termination notice showing "Outstanding Investigator Grants"

A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted

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Abby Polter @ampolter.bsky.social · 15/05/2025

I am thinking a lot today about how heavy things feel in my world of faculty doing scientific research. There's the immediate chaos and panic about our ability to pay people and continue our research. But there's also a deeper grief at watching everything get bulldozed for no reason

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Stacey Ogden 🦔 @labogden.bsky.social · 15/05/2025

I never imagined I would see something like this happen to federally funded research in the US. I am heartbroken for all the researchers whose grants have been terminated and devastated for all the patients whose current (and future) treatments are being impacted 🧪 💔

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Craig Kaplan @triggerloop.bsky.social · 15/05/2025

Current situation at Harvard Medical School for NIH grants view.u.hms.harvard.edu?qs=3ed8c01b9...

view.u.hms.harvard.edu

Harvard Medical School

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Jeremy Berg @jeremymberg.bsky.social · 12/05/2025

Slow grant making continues. Here is a graph through May 1st. 2/n

A graph with clusters gray curves showing NIH grant making for fiscal years 2015-2024 with a red curve showing slower grant making in fiscal year 2025.

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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

media.tenor.com

the word alert is in a purple circle

ALT: the word alert is in a purple circle

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Jeremy Berg @jeremymberg.bsky.social · 23/03/2025

Many hundreds (perhaps up to 1000) of additional NIH grants appear to be have been terminated on Friday. I have updated the data from the HHS TAGGS site (and converted it from a pdf to an Excel file) on the dashboard but many hundreds are still missing. jeremymberg.github.io/jeremyberg.g...

jeremymberg.github.io

NIH_since_1_20_25

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Rebecca Fielding-Miller @rebeccafieldingmiller.com · 22/03/2025

Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women. More women are murdered in the perinatal period than die of obstetric complications. I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.

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Scott Delaney @scott-delaney.bsky.social · 21/03/2025

The crush of new grant cancellations hasn't let up. If your grant was terminated (or your app was pulled) please use this Google Form👇 to submit details for tracking purposes. Multiple advocacy efforts are moving forward, but we must must must know more about what grants were cancelled and why.

forms.gle

Cancelled NIH grant information submission form

Please use this form to submit information identifying specific NIH grants that have been cancelled for any reason after January 20, 2025. Data from this form will be used to update the Rescinded NIH...

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Jeremy Berg @jeremymberg.bsky.social · 21/03/2025

ATTENTION If you are someone (or know someone) who is enrolled in an NIH-funded clinical trial that has been disrupted by grant uncertainties or terminations, please DM me. THANK YOU!

media.tenor.com

stan marsh from south park says see that 's what happened to me !

ALT: stan marsh from south park says see that 's what happened to me !

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Dave Baltrus 🦦 @surtlab.bsky.social · 15/03/2025

In my 25 years since high school I’ve seen 1. HIV/AIDS go from death sentence to manageable with drugs 2. Cystic fibrosis go from pretty much an extended death sentence to manageable with drugs 3. Sickle cell go from a horrible disease to (almost maybe) cured by gene therapy Simply incredible

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Congresswoman Pramila Jayapal @jayapal.house.gov · 10/03/2025

This is shameful. I have met with many NOAA scientists in our district. Their work monitoring extreme weather and addressing the climate crisis is critical. We must advocate for NOAA and stand with the workers who were unjustly fired. www.seattletimes.com/seattle-news...

seattletimes.com

Federal NOAA cuts hit Seattle offices

Sen. Maria Cantwell was quick to criticize the move and characterized it as a "direct hit" on the economy.

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BWJones @bwjones.bsky.social · 03/03/2025

1) The "cuts" that DOGE/Trump/Musk are doing are things that stimulate the economy. Some, like NIH return multiples to the economy. 2) The job cuts are spooking people. When people are spooked, they don't spend money. 3) Cutting contracts sends the message that America does not pay its bills.

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Science Homecoming @sciencehomecoming.bsky.social · 01/03/2025

Anne Carpenter writes about the science cuts: “this is like suddenly announcing that you will pay for doctors and nurses but not the hospital building they work in” for the LaPorte Herald Dispatch in IN 🌽 🧪🧬🔬🏠 @drannecarpenter.bsky.social www.lpheralddispatch.com/opinion/gues...

lpheralddispatch.com

Indiana’s health and economy depends on U.S.-funded science

When people ask me what city I’m from, I say I’m not from a city – I’m from a county!

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Katie Phang @katiephang.bsky.social · 27/02/2025

NEW: “Kennedy paused a multimillion dollar project to create a new Covid-19 vaccine in pill form on Tuesday, and the Food and Drug Administration canceled an advisory committee meeting on updating next season’s flu vaccine.” newrepublic.com/post/192059/...

newrepublic.com

RFK Jr. Takes a Sledgehammer to Two Major Vaccine Developments

Robert F. Kennedy Jr. is already implementing his dangerous anti-vax views at HHS.

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Meg K. 🌊🏔️❄️ @c2snow.bsky.social · 28/02/2025

We’ve tried to shelter our minds but tonight we’re preparing for the genocide of Science. Entire NIH departments will have no leaders. World renowned Scientists kicked to the curb without cause, & grants will loose their lead investigators. Is this what they want? Chaos? Destruction?

science.org

NIH ban on renewing senior scientists adds to assaults on its in-house research

Policy follows firings of tenure-track scientists and suspension of training programs

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Bill Kristol @billkristolbulwark.bsky.social · 28/02/2025

Very encouraging news about cancer research and mRNA vaccines. An administration that cared about Americans' well-being would be looking for ways to follow up and double down on such efforts. The Trump administration on the other hand seems determined to gut NIH and is hostile to vaccines.

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Bill Kristol @billkristolbulwark.bsky.social · 28/02/2025

So: We have news of very promising developments in cancer treatment with mRNA vaccines. The Trump administration wants to gut cancer research and hamper the development of mRNA vaccines.

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Dave Levitan @davelevitan.bsky.social · 19/02/2025

The head of the Autism, ADHD, and Externalizing Disorders Interventions Research Program at the National Institute of Mental Health was fired over the weekend, 21 days shy of the end of her one year probationary period. She posted about it on fb.

This-despite a stellar performance review weeks ago.
This-despite receiving an NIMH Director's Award.
This-despite being recruited SPECIFICALLY for my subject matter expertise in autism and neurodevelopmental disabilities, clinical trials, and community-based effectiveness research.

After two decades in academic research and advocacy, I was hired to help develop ways to get low-cost, evidence-based mental health care into schools and community settings-so ALL kids could access specialized treatment, not just those with private insurance or parents who could take time off work.

I didn't take the move to NIMH lightly-I went because I believed in shaping the future of autism and mental health research, impacting policy, and ensuring that science actually reaches the communities that need it most. And I LOVED my job. I found that same community in my division.

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Matt Might @matt.might.net · 16/02/2025

As a parent to a child with special needs, I can’t even begin to tell you how heartbreaking it is to see this.

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