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Jan Mašek

@maseklab.bsky.social
256 followers 202 following 52 posts

PI at CUNI Prague🇨🇿, Karolinska Institutet🇸🇪, Czexpat🌍, Junior Faculty chair. Notch & Wnt in development and disease 🔬🧫🐁. *All views my own; 🇪🇺🇺🇦 maseklab.org

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Jan Mašek @maseklab.bsky.social · 27/05/2026
Go Anna go!
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Jan Mašek @maseklab.bsky.social · 07/05/2026
Excited to share our new study, now out on bioRxiv: www.biorxiv.org/content/10.6... In this work, we identify CK1α as a novel positive regulator of NOTCH1 signaling and uncover a previously unknown phosphorylation-dependent regulatory mechanism centered on N1ICD residue S1970.
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Peter Fabian @fabianlab.bsky.social · 03/02/2026
Today at PI_Forum Brno we will discuss this graph. From 62% women at PhD level to 17% at professor level. Let’s talk about why this happens—and how to change it. 📍 CEITEC MU | 🕠 17:30 czexpats.org/en/udalost/p... @czexpats.bsky.social
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Jan Mašek @maseklab.bsky.social · 27/01/2026
Paper alert! 🤓 Cells talk to one another all the time using cascades of protein interactions. Now, we know for quite some time that proteins from different cascades can interact with each other. It's called crosstalk. But doesn't it defy the logic of clear communication channels between cells? 🧐
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Jakub Tomek @jakubtomek.bsky.social · 09/12/2025
Author copies of our new book on statistics (mainly) for life scientists arrived recently. After three years of work, this is exciting, especially as we really hope it can help make a positive difference. What's so special about it? 🧵
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Jan Mašek @maseklab.bsky.social · 03/12/2025
Great article about starting a lab at @sciencecharles.bsky.social and the positive effect of supportive peer community from my colleague and co-chair of JF Vito @geohazards.group. For more context check also my article in @vedavyzkumcz.bsky.social - vedavyzkum.cz/nazory/nazor....
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Jan Mašek @maseklab.bsky.social · 22/10/2025
15th PhD Conference in Dev Cell biology just started and it looks like another year packed with great science, opening with brilliant @ruibenedito.bsky.social keynote!
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Emma R Andersson @anderssonlab.bsky.social · 27/09/2025
👩‍🔬👨‍💻 Postdoc recruitment! 👨‍🔬👩‍💻 Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms. 🚨 Deadline Oct 1st!! 🚨 Please re-post and help us spread the word far and wide! ✈ ki.varbi.com/en/what:job/...
ki.varbi.com
Postdoctoral studies in next generation single cell lineage tracing of skin (scholarship)
Do you want to contribute to top quality medical research? A postdoctoral scholarship is available in the lab of Emma R Andersson at the Department of Cell and Molecular Biology, Karolinska Institutet
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Sofya Garushyants @garushyants.bsky.social · 15/09/2025
hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
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Oded Rechavi @odedrechavi.bsky.social · 31/07/2025
🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...
nature.com
Scientific bedlam at the world’s weirdest and wildest research conference
Woodstock Bio2 + Night Science aimed to encourage collaborations through creativity. The walk-on music for presentations was fun, too.
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Lynn Chiu @drlynnchiu.bsky.social · 20/07/2025
Read all Elements in The Philosophy of Biology series for FREE during the ISHPSSB conference 20 - 25 July. You can find all of these Elements free to download and read here: cup.org/4kEgivL
cup.org
Philosophy of Biology
Welcome to Cambridge Core
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MwahahahahahadScientist @mads100tist.bsky.social · 17/07/2025
We should have the equivalent for PIs looking for students and/or postdocs
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John Wallingford @jbwallingford.bsky.social · 11/07/2025
Birth defects kill twice as many children as cancer. Animal model are crucial; no stem-cell or computer models can yet recapitulate the embryo's complexity. If you support birth defects research tell NIH that animal models are important! Click & scroll below to comment. tinyurl.com/mr3he6bx
tinyurl.com
FDA-NIH Workshop: Reducing Animal Testing
The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.
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Czexpats in Science @czexpats.bsky.social · 06/07/2025
🍂 Podzimní London calling je opět tady! 🗣️ 🔗 czexpats.org/udalost/setk...
czexpats.org
Setkání českých vědkyň a vědců v Londýně 2025 - Czexpats in Science
V pořadí třetí setkání českých vědkyň a vědců působících ve Velké Británii se uskuteční v pátek 19. září v Londýně. Akce vzniká pod záštitou Czexpats in Science, ve spolupráci s Velvyslanectvím České ...
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paveltomancak.bsky.social @paveltomancak.bsky.social · 26/06/2025
Read this piece. It gives a great impression of #TCTeAC WoodstockBio2 & Night Science from one of the #Instigators. This is the next best thing to being there... I like the expression #BohemianFixers. Many thanks to them! Děkujeme. thenode.biologists.com/from-posters...
thenode.biologists.com
From Posters to Parades: Inside Woodstock.Bio² & Night Science Conference - the Node
A fever dream of science and spirit wrapped in the forests of Bohemia. Here’s an escalating list — starting with the standard (though nothing was standard
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Rui Benedito @ruibenedito.bsky.social · 26/06/2025
The new Department of Functional Genetics at the Max Planck Institute for Molecular Biomedicine is looking for scientists at any level. 👉 mpi-muenster.mpg.de/780013/profil
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Itai Yanai @itaiyanai.bsky.social · 16/06/2025
I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.
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Peter Fabian @fabianlab.bsky.social · 13/06/2025
This might be useful for the #TCTeAC participants 🇨🇿, 🙏 @svobodalab.bsky.social @odedrechavi.bsky.social @itaiyanai.bsky.social go.bsky.app/DPH6r8o
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Jan Mašek @maseklab.bsky.social · 11/06/2025
Super nice talk by @jesseveenvliet.bsky.social on how the environment restricts the possible courses of embryonic development 🤓 #TCTeAC
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Jan Mašek @maseklab.bsky.social · 11/06/2025
@honzadobes87.bsky.social nailing his talk at WoB2 conference #TCTeAC
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Jan Mašek @maseklab.bsky.social · 11/06/2025
That was a brilliant talk Ahmed! Thank you! #TCTeAC
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Čajánek lab @cajaneklab.bsky.social · 10/06/2025
📣Check out our recent review (written with Martina Huranova lab) on converging mechanisms controlling #cilia #dynamics during #cell #cycle, #cell #signaling, and cross-talk of ciliary modules. rdcu.be/epVDc
rdcu.be
Cilia at the crossroad: convergence of regulatory mechanisms to govern cilia dynamics during cell signaling and the cell cycle
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Czexpats in Science @czexpats.bsky.social · 18/05/2025
English-speaking colleagues welcome! Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎 If you’re planning to join us, let us please know via the link above 🙏
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epithelial mechanics fan club @epimechfc.bsky.social · 18/05/2025
Let's talk about a party—where drugs don't hit the dance floor but finely tune #EpithelialMechanics by hitting actomyosin cortex! 🧬💊 Here's our guide to doing drugs 🧵
poster
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 01/05/2025
We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA" May 13, 4PM CET Registration link: tinyurl.com/prose-seminar4 Please share!
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Claudio Cantù @claudiocantu81.bsky.social · 12/05/2025
We had previously shown that TBX3 and #WNT cooperate in limb #DevBio We now have a shocking finding, just published in @pnas.org TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC) www.pnas.org/doi/epub/10....
pnas.org
The developmental factor TBX3 engages with the Wnt/β-catenin transcriptional complex in colorectal cancer to regulate metastasis genes
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Czexpats in Science @czexpats.bsky.social · 30/04/2025
🌟 #PI_Forum Brno #5: Academic Leadership: The Big Picture is ahead! How does one lead a team vs. an institution? Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond. 🗓️ 13 May 2025 📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...
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Erik van Nimwegen @erikvannimwegen.bsky.social · 09/05/2025
Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social. I'm so excited about this! www.biorxiv.org/content/10.1...
biorxiv.org
Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data
Single-cell omics methods promise to revolutionize our understanding of gene regulatory processes during cell differentiation, but analysis of such data continues to pose a major challenge. Apart from...
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IOCB Prague @iocbprague.bsky.social · 06/05/2025
🤝 IOCB Prague is hiring – we are looking for an outstanding Junior Group Leader in Biosciences to join our vibrant scientific community. See more ► www.uochb.cz/en/open-posi... ⤵️ #openposition #iocbprague #iocb #researchjobs #biosciences
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Czexpats in Science @czexpats.bsky.social · 07/05/2025
📢 Tři osobnosti, tři příběhy, tři vědecké světy - takové bylo předávání druhého ročníku letošní Ceny Czexpats In Science! Celý článek již na našem webu ⏬ czexpats.org/clanek/tri-o...
czexpats.org
Tři osobnosti, tři příběhy, tři vědecké světy. Takové bylo předávání druhého ročníku Ceny Czexpats in Science. - Czexpats in Science
Cenu Czexpats in Science pro mladé vědce a vědkyně působící v zahraničí letos získali tři výrazné osobnosti – bioinformatička Monika Čechová, právník Jakub Drápal a expert na umělou inteligenci Stanis...
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Jan Mašek @maseklab.bsky.social · 02/05/2025
Honored to receive these t-shirts, learning the powerful story of Roberta Smith from the Alagille Syndrome Alliance behind them. 💛 www.linkedin.com/in/roberta-s...
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George Burslem @gburslem.bsky.social · 01/05/2025
Excited to see this out in @science.org today!! www.science.org/doi/10.1126/...
science.org
Intracellular protein editing enables incorporation of noncanonical residues in endogenous proteins
The ability to study proteins in their native cellular context is crucial to our understanding of biology. In this work, we report a technology for intracellular protein editing, drawing from split in...
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Jan Mašek @maseklab.bsky.social · 22/04/2025
Awesome day full of scientific discussions with David Sprinzak, who came to give a talk about inner ear patterning at our Dpt seminar series. natur.cuni.cz/en/biology/d... Huge thanks for coming, David!
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Petr Svoboda @svobodalab.bsky.social · 17/04/2025
#theconferencetoendallconferences ... if you want to join, hurry up, we will be full soon. The capacity is limited (lecture hall size) to 230 paying. 227 registered, 188 paid as of now. What you've heard is likely true. Science + music & magic, train, canoes ... (Faust too). woodstock.img.cas.cz
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Zebrafish Rock! @zebrafishrock.bsky.social · 16/04/2025
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Jess McLaughlin, PhD (they/them) @jfmclaughlin92.bsky.social · 12/04/2025
alright i have my laptop, guess i'm livetweeting the dire wolf preprint. so a quick reminder: this is not yet peer-reviewed, so there's some different expectations re: quality. also let's be clear, i'm a hella biased reader, bc i don't trust the hype they're courting
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Czexpats in Science @czexpats.bsky.social · 07/04/2025
Potkejme se v Kodani! 🇩🇰🤗 Do 21. dubna se můžete registrovat na další z našich lokálních setkaní českých vědkyň a vědců působících v zahraničí ➡️ forms.gle/YVfJCjiG1PbZpW… Těšíme se na vás!
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Czexpats in Science @czexpats.bsky.social · 04/04/2025
V květnu se opět potkáme v Haagu! 🌷🚲🧀 Keynote přednášky přednesou Sacha Prechal (@utrechtuniversity.bsky.social), Václav Valenty (@esa.int) a @katquita.bsky.social, a těšit se můžete i na účastnické flash talks. 🌟 📝 Registrace nutná! Více informací najdete na 👉 czexpats.org/udalost/setk...
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Emma R Andersson @anderssonlab.bsky.social · 04/04/2025
Hot off the press! 🧬🔬 We developed in utero nano-injection to label & trace the mouse neural plate and otic placode using next generation single cell lineage tracing. We couple progenitors to mature cell types in the CNS & resolve the lineages of cells in the hearing organ: doi.org/10.1126/scie...
doi.org
Ectoderm barcoding reveals neural and cochlear compartmentalization
Placodes and the neural crest are defining features of vertebrates. In this study, we investigate their lineages in mice using in utero approaches. We demonstrated that nanoinjection at embryonic day ...
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Czexpats in Science @czexpats.bsky.social · 03/04/2025
🏆 Již za dva týdny proběhne Slavnostní předávání Ceny Czexpats In Science v Brně. Součástí předávání budou přednášky a společná diskuze laureátů Moniky Čechové, Jakuba Drápala a @stanislavfort.bsky.social. 💫 📰 Více o jejich výzkumu si můžete přečíst již nyní 👉 czexpats.org/clanek/druhy....
czexpats.org
Druhý ročník Ceny Czexpats in Science má tři laureáty - Czexpats in Science
Laureáty druhého ročníku Ceny Czexpats in Science se stali bioinformatička Monika Čechová, právník Jakub Drápal a AI vědec Stanislav Fort. Ocenění převezmou 16. dubna na půdě Masarykovy univerzity v B...
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Petr Svoboda @svobodalab.bsky.social · 02/04/2025
Woodstock.Bio 2 & Night Science is the meeting where organizers register & pay like others! If you want to be a part of this unforeseen, unique, unbelievable, unforgettable, unpredictable & untouchable meeting, there's dozens of places left. It's 230 PAYING! Beyond that is the waiting list.
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Jan Mašek @maseklab.bsky.social · 01/04/2025
Very proud of our PhD student Anna, and grateful to GAUK for funding her 2-year project on 3D visualisation of liver mesenchyme under cholestatic condition. Well deserved!
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Alfonso Martinez Arias @amartinezarias.bsky.social · 28/03/2025
This is, indeed, an important and valuable contribution to the standardization of an experimental system that is beginning to show promise and teach us unexpected featured of mammalian development.
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Yaniv Elkouby @yanivelkouby.bsky.social · 17/03/2025
🐟🐟🐟 We are looking for the floxed dnStat3 line (pd59Tg) - Tg(actb2:LOXP-DsRed-STOP-LOXP-dnstat3-GFP), which was generated by the Poss lab (or similar). If anyone maintains the line and able to kindly share embryos, that would be much appreciated. Thanks! @zebrafishrock.bsky.social
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Oded Rechavi @odedrechavi.bsky.social · 09/03/2025
Half sold out in a week!
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Oded Rechavi @odedrechavi.bsky.social · 09/03/2025
The archetype of the scientist who sacrifices everything might’ve been romantic 50 years ago when there weren’t alternative high paying jobs. If we won’t make science FUN, reduce bureaucracy, and make it easier to secure funding and publish, few will stay in academia.
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paveltomancak.bsky.social @paveltomancak.bsky.social · 09/03/2025
At #Woodstockbio2025 #selforganization is key. If you plan to do something special at the #YMCAcampsite, go for a talk & work the #advertisement of the #event into your ~5 minutes of fame in #Prague - after the #walkupsong #TheConferenceToEndAllConferences (what a hashtag🤷🏻‍♂️) woodstock.img.cas.cz
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Oded Rechavi @odedrechavi.bsky.social · 01/03/2025
Friends! The science that we love is under threat. World-wide, there're forces seeking to make it corporate-like, focused on deliverables, or even the enemy of society. Take a stand & celebrate science & music! #theconferencetoendallconferences - Registration starts NOW! woodstock.img.cas.cz
woodstock.img.cas.cz
Woodstock.Bio2 + Night Science 2025 | Courses & Meetings
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Petr Svoboda @svobodalab.bsky.social · 01/03/2025
#theconferencetoendallconferences woodstock.img.cas.cz The website is up & registration is open!
media.tenor.com
three men in armor are standing next to each other with the words and so it begins below them
ALT: three men in armor are standing next to each other with the words and so it begins below them
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Jan Mašek @maseklab.bsky.social · 28/02/2025
Today's oval office bullying asks for a response, the only meaningful I could figure is to send more money to Ukraine, please consider doing the same. www.weaponstoukraine.com
zbraneproukrajinu.cz
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