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Claudia Alvarez Carreño

@claudiaalcar.bsky.social
904 followers 548 following 32 posts

Protein structure evolution | Royal Society Newton International Fellow at UCL | she/her

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Reposted by Claudia Alvarez Carreño
Mar Albà lab @maralbalab.bsky.social · 04/10/2026
We are recruiting!! EU-funded PhD position to study the evolution of small proteins - from noise to function Apply before Oct 22 albagroup.researchmar.net/positions www.orfeus-dn.eu @grib-barcelona.bsky.social @prbb.org @researchmar.bsky.social @official-smbe.bsky.social @sciencehr.bsky.social
albagroup.researchmar.net
Mar Albà 's evolutionary genomics LAB: Open Positions
work with us at the evolutionary genomics lab
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 30/09/2026
#NeurIPS results are out! We can finally share LEMON (Layered Extraction of Molecular Ordering from Nature), a compact 200M-parameter model for detection of remote homologs powered by ZEST (Zoned Encoding of Sequence Traits) Amazing work led by Biswajit Banerjee and Anton S Petrov at GeorgiaTech
arxiv.org
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 08/09/2026
Don’t miss today’s ProSE seminar!
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Reposted by Claudia Alvarez Carreño
Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 01/09/2026
Join us next Tuesday, 5PM CET for our first ProSE after the summer! Betül Kaçar @kacarlab.bsky.social will talk about the origin and early evolution of ancient proteins! 📜🧬 tinyurl.com/prose-seminar2
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 06/08/2026
TEDLH is out! 🎉 A library of 900K+ HMMs for sensitive protein domain searches, built from TED and mapped to CATH (@cathgene3d.bsky.social). Give it a look! #Bioinformatics #ProteinDomains Paper: doi.org/10.1093/bioi... Library: doi.org/10.6084/m9.f...
doi.org
TEDLH: domain HMMs for sensitive detection of remote homologues
AbstractMotivation. The Encyclopedia of Domains (TED) provides domain annotations for proteins in the AlphaFold Protein Structure Database (AFDB) using a c
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Joseph M. Adelman @jmadelman.bsky.social · 31/07/2026
Because the 1st is a Saturday, “How is it August already?!” will be observed today, Friday, July 31, 2026. Please panic accordingly.
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 08/06/2026
Don't miss the last ProSE seminar before summer break! We're excited to have César Ramírez-Sarmiento @cesarramirez.bsky.social presenting. Register here: tinyurl.com/prose-seminar2 @proteinstructure.bsky.social
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Reposted by Claudia Alvarez Carreño
The Royal Society @royalsociety.org · 05/06/2026
Professor Joe Felsenstein FRS is elected a Fellow of the Royal Society. After initially working on population genetics theory of recombination, of migration, and of speciation, his main focus has been on phylogenetic inference. #RSFellows royalsociety.org/people/joseph-fels…
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Cesar A. Ramirez-Sarmiento @cesarramirez.bsky.social · 05/06/2026
I will be talking about the fold-switch and evolution of RfaH next week, in case you are interested. Thanks @claudiaalcar.bsky.social for the invitation to participate!
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Reposted by Claudia Alvarez Carreño
Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 04/06/2026
Join us the last time before the summer break! Cesar A. Ramirez-Sarmiento will talk about "Unveiling the fold-switching behavior of RfaH: echoes of the past, signals of the present". As always, Tue 5PM CET, follow the link to sign-up: tinyurl.com/prose-seminar2
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 18/05/2026
I am VERY disappointed to learn that the Gordon Research Conferences have capitulated to the fascists and ended their long standing "Power Hour" programs where we could speak together as a community about challenges and approaches to address the experiences of all
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 12/05/2026
Dont't miss today's seminar by Noelia Ferruz! May 12, 5PM CET Registration link: tinyurl.com/prose-seminar2 Past seminars: tinyurl.com/ProSE-videos
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Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 05/05/2026
Join ProSe next week Tuesday, when Noelia Ferruz @noeliaferruz.bsky.social is talking about "Controllable Protein Design with Protein Language Models and Reinforcment Learning", TUE, May 12, 5PM CET! Sign-up here: tinyurl.com/prose-seminar2
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Reposted by Claudia Alvarez Carreño
ancientbio-peru.bsky.social @ancientbio-peru.bsky.social · 15/04/2026
🚨 Good news! Abstract deadline Extended! 🚨 Don’t miss your chance to be part of the meeting. Submit your abstract by May 15th, 2026. Meet our invited speakers, share your research, and connect with the community. ✨
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Reposted by Claudia Alvarez Carreño
NASA Artemis @artemis.extwitter.link · 11/04/2026
"Planet Earth: You. Are. A. Crew." Artemis II mission specialist Christina Koch reflects on what it means to be a "crew."
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Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 08/04/2026
Our next speaker will be Timothy Fuqua @timothyfuqua.bsky.social with "The Evolution and Emergence of Regulatory DNA", 14th April, 5PM CET. Sign-up here: tinyurl.com/prose-seminar2
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Zachary Ardern @zachary-ardern.bsky.social · 30/03/2026
My new mini article exploring recent developments using the phylogeny of genomes to improve data compression and the computational efficiency of some key tasks in genomics 🧬 rdcu.be/faKgm
rdcu.be
Leveraging microbial phylogeny for computational efficiency
Nature Reviews Microbiology - This Genome Watch article explores how taking into account known phylogenetic relationships can improve computational efficiency for genomics, enabling improved genome...
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ISCB News @iscb.bsky.social · 31/03/2026
🇵🇪 Tutorial proposals are open for #LATAM2026! We're seeking hands-on tutorials in cutting-edge #bioinformatics topics. Help attendees build knowledge, learn new research areas, or develop advanced skills. 📅Deadline: May 13 Submit here: www.iscb.org/latam2026/call-for-sub…
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Klara Hlouchova lab @hlouchova-lab.bsky.social · 26/03/2026
To all early life enthusiasts🦠 How did we get from soups of chemicals to the Last Universal Common Ancestor? 🌋 Help us bridge the gap at A Road to LUCA in beautiful Prague! 🇨🇿 ⏳ 1 WEEK until the abstract deadline! Explore here: natur.cuni.cz/en/aroadtoluca
natur.cuni.cz
JME: A Road to LUCA
With support from Journal of Molecular Evolution and its editorial board, we are proud to organize “ JME: A Road to LUCA - Filling the gap between prebiotic chemistry and life as we know it ”, our ...
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MPI for Biology Tübingen & Friedrich Miescher Laboratory @mpi-bio-fml.bsky.social · 23/03/2026
DSSS continues this Thursday with speaker Dr. Benjamin Podbilewicz who has thankfully managed to join us from Technion in Haifa, Israel. Everyone welcome! ▶️More info: tinyurl.com/27cedwft 📆: Thursday 26th March at 11am 📍: MP-Intelligent Systems seminar room, ground floor #DSSS #MP-IS
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Timothy Fuqua @timothyfuqua.bsky.social · 17/03/2026
ERC starting grant eligibility window increased to 10 years post-PhD defense: www.ukro.ac.uk/news/changes...
ukro.ac.uk
Changes to the 2026 and 2027 ERC Work Programmes
With the upcoming ERC Work Programme 2026 this July, several changes to the submission of applications and the evaluation of proposals will apply. The main novelties for 2026 and 2027 are are summaris...
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Reposted by Claudia Alvarez Carreño
Society for Molecular Biology and Evolution @official-smbe.bsky.social · 12/03/2026
🧬EvolCompGen presents: Christian Landry on the Evolution of gene duplication, from redundancy to dependency @christianlandry.bsky.social 🗓️ Join us on Monday, March 23 at 11:00 AM EDT 📌 Register here: us02web.zoom.us/webinar/regi...
EvolCompGen presents: Christian Landry on the Evolution of gene duplication, from redundancy to dependency
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Hassan uz Zaman @hassanzaman.bsky.social · 09/03/2026
This talk is happening tomorrow—as part of the Protein Structure Evolution seminar! Click here to register if you like cool science: tinyurl.com/prose-seminar2 Organized by @lacholt.bsky.social, @caro-rocha.bsky.social, @claudiaalcar.bsky.social, @zachary-ardern.bsky.social and myself.
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Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 03/03/2026
Our next Talk will be "Protein Origami and the Hidden Rules of Functional Innovations"! March 11th, 5PM CET. Sign-up here: tinyurl.com/prose-seminar2
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Zebrafish Rock! 🎃 @zebrafishrock.bsky.social · 28/02/2026
Today is #RareDiseaseDay & we are celebrating by highlighting the invaluable work of the Undiagnosed Diseases Network (UDN)! Formed in 2020, it aims to solve the most challenging medical mysteries using advanced technologies. In this thread, we will highlight their use of the #zebrafish model. 1/5 🧪
Logo for the Undiagnosed Diseases Network (UDN). It shows a the letter UDN is different colors that overlap to form the analogous colors.
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 10/02/2026
Starting in less than an hour! Register to join: tinyurl.com/prose-seminar2
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Ashmolean Museum, Oxford @ashmoleanmuseum.bsky.social · 08/02/2026
If the hashtag #SuperBowl has you wondering where the superb owls are…we got you! 🦉Detail from Owl, 1601–1800. EA2012.344.b 🦉An owl on a branch, 1893–1898, Sir Edward Coley Burne-Jones (1833–1898). WA2015.68.29 🦉Owl, 1865, Arthur Burgess (1843–1886). WA.RS.RUD.046
A gouache painting of an owl with blue eyes facing towards the viewerA pen and ink drawing of an owl perched on a branch with its eyes closed.A haunting charcoal and chalk drawing of an owl perched on a branch in the night
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Tom Williams @tweethinking.bsky.social · 06/02/2026
meetings.embo.org/event/26-mic... Announcing the 2026 EMBO course in Computational and Experimental Microbiomics, to be held at Bath. The course brings together experiments and bioinformatics to study host-microbe interactions and co-evolution. Register now, or at least by 11 May, if interested :)
meetings.embo.org
Computational and experimental microbiomics
The critical contribution of microbiota to animal, plant and environmental health is now widely accepted. Progress has been driven by two parallel approaches: in silico analyses of large -omics data …
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Origin of Life Early-Career Network @oolen.bsky.social · 05/02/2026
Curious about how life began? OoLEN is a global community for early-career researchers in origins of life and prebiotic chemistry. 🧬🌍 Connect with others across disciplines, find opportunities, and grow together. Join: oolen.org/join Tell us in the replies—what do you work on? #OriginOfLife
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Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 03/02/2026
Next up in our ProSE seminar series: Vyacheslav Tretyachenko on alternative translation in the human proteome Register to join: tinyurl.com/prose-seminar2 Past seminars: tinyurl.com/ProSE-videos
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Hassan uz Zaman @hassanzaman.bsky.social · 03/02/2026
Come one, come all to the first Protein Structure Evolution talk of the year (Feb 10)! Click here to register if you like cool science: tinyurl.com/prose-seminar2 Jointly organized by @lacholt.bsky.social, @caro-rocha.bsky.social, @claudiaalcar.bsky.social, @zachary-ardern.bsky.social and myself.
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Klara Hlouchova lab @hlouchova-lab.bsky.social · 03/11/2025
Can proteins fold and function with half of the amino acid alphabet? Using only 10 residues, we designed stable, mutation-resilient structures—no aromatics or basics involved. A minimalist foundation for ancient biology and synthetic design. tinyurl.com/37t8br4v #ProteinDesign #OriginsOfLife
tinyurl.com
Ancient amino acid sets enable stable protein folds
Early proteins likely arose from a chemically limited set of amino acids available through prebiotic chemistry, raising a central question in molecular evolution: could such primitive compositions yie...
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Rachel Nuwer @rachelnuwer.bsky.social · 22/01/2026
With most psychedelic drugs, you never know what you're going to get. But this mysterious mushroom from China - without fail - causes users to hallucinate tiny people: crawling up walls, popping out from under furniture and marching under doors. www.bbc.com/future/artic...
bbc.com
'They saw them on their dishes when eating': The mushroom making people hallucinate dozens of tiny humans
Only recently described by science, the mysterious mushrooms are found in different parts of the world, but they give people the same exact visions.
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Working Class History @workingclasshistory.com · 22/01/2026
#OtD 22 Jan 2018 legendary anarchist author Ursula K Le Guin died aged 88 in Portland, Oregon. An ardent feminist and advocate for diversity in literature and publishing, she won numerous awards for her work. We have made available some of her books here: shop.workingclasshistory.com/collections/...
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Victor Tobiasson @victortobiasson.bsky.social · 18/01/2026
FYI were starting weird structure/evolution/biology stuff at Glasgow University! If you're interested let me know! Tell your friends! CRYO www.jobs.gla.ac.uk/job/research... BIOINFO www.jobs.gla.ac.uk/job/research... TECHNICIAN www.jobs.gla.ac.uk/job/technici... #science #hiring #evolution
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 09/01/2026
Thrilled to introduce TEDLH, a library of profile HMMs built from TED’s structure-derived domain annotations of the AFDB. Explore 765K HMMs capturing CATH superfamily diversity. www.biorxiv.org/content/10.6...
Construction of TEDLH from TED domain annotations.
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Stephen Royle @steveroyle.bsky.social · 16/12/2025
Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there?? #CellBiology #WTFology www.biorxiv.org/content/10.6...
biorxiv.org
The vault associates with membranes in situ
The eukaryotic vault particle is a giant ribonucleoprotein complex that assembles into an iconic barrel-like cage. Its cellular function has remained elusive despite extensive characterization. Using ...
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Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 28/10/2025
The next ProSE Seminar will be given by Joana Pereira @joanampereira.bsky.social (VIB, KU Leuven) 🗓️ November 11th, 5pm CET Registration is now open: tinyurl.com/prose-seminar2 Please share!
Protein Structure Evolution Seminar
November 11, 5pm CET
Title: AI-Powered Classification and Discovery Across the Protein Universe
Speaker: Joana Pereira
Organized by: Claudia Alvarez Carreno, Zachary Ardern, Lars Eicholt, Carolina Sanchez-Rocha, Sergio Romero-Romero and MD. Hassan Uz-Zaman
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Lars Eicholt @lacholt.bsky.social · 28/10/2025
Join our next ProSe seminar 11th November 5PM CET and follow us @proteinstructure.bsky.social!
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Protein Structure Evolution (ProSE) Seminar @proteinstructure.bsky.social · 25/10/2025
Protein Structure Evolution (ProSe) Seminar is now on BlueSky! Every 2nd Tuesday, 4PM GMT. Sign-Up: tinyurl.com/prose-seminar2 Organized by Claudia Alvarez Carreño, Zachary Ardern, Lars Eicholt, Carolina Sanchez-Rocha, Sergio Romero Romero and Md. Hassan Uz-Zaman.
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Klaus Paschek @klauspaschek.bsky.social · 22/10/2025
I'll be featured at the outreach event of the Science Café in Nijmegen 🇳🇱, talking about astrochemistry and the origins of life and its building blocks in space and on early Earth. Stop by if you're in the area on Thu, Oct. 23, 7.45 PM. Admission is FREE, and there will be jazz! 🎶🎷🌌🔭☄🦠
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Gonzalo Parra @gonzaparra.bsky.social · 22/10/2025
Last week to apply to join our recently created lab as a PhD Student! Join us to research about protein computational biophysics, evolution, machine learning , and human mutations! Description and link to apply here: www.bsc.es/join-us/job-...
bsc.es
596_25_LS_ESB_R1
Reference: 596_25_LS_ESB_R1 Job title: PhD student in computational biophysics and machine learning (R1, FPI)   About BSC   The Barcelona Supercomputing Center - Centro Nacion
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 06/10/2025
The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU): Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t” Date: October 14th, 5 pm CET Registration link: tinyurl.com/prose-seminar2
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Claudèle Lemay-St-Denis @claudele.bsky.social · 08/10/2025
How does catalysis emerge from non-catalytic domains? In our new paper, we show that catalytic activity can arise without conserved active-site residues — through multimerization and electrostatic features instead. A striking case of catalysis evolving from binding.
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 06/10/2025
The next Protein Structure Evolution Seminar will be given by Stephen Fried (JHU): Title: “Who Cares About Protein Refolding Anyway?: Why Some Microbes Do and Others Don’t” Date: October 14th, 5 pm CET Registration link: tinyurl.com/prose-seminar2
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Nature @nature.com · 22/09/2025
Modelling suggests that most Caribbean coral reefs will erode by the year 2100 as sea-level rise outpaces reef growth and limits potential reef restoration go.nature.com/42229kK
go.nature.com
Caribbean coral reefs are threatened by rising seas
Modelling suggests that most Caribbean coral reefs will erode by the year 2100 as sea-level rise outpaces reef growth and limits potential reef restoration.
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Jeremy Berg @jeremymberg.bsky.social · 20/09/2025
ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS Comment period ends September 29th www.federalregister.gov/documents/20... 1/2
federalregister.gov
Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media
Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 15/09/2025
Happy to share Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record 🧪 It appears as part of a Special Section in @genomebiolevol.bsky.social organized by @cpuentelelievre.bsky.social @proteinmechanic.bsky.social and J. Douglas doi.org/10.1093/gbe/...
doi.org
Piecing Together the History of Protein Folds From a Fragmented Evolutionary Record
Abstract. Protein folds are structural units defined by the number, type, arrangement, and orientation of their core secondary structural elements. The uni
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 02/09/2025
The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space". Date: September 9 Time: 5pm CET Register here: tinyurl.com/prose-seminar2 Please share! 🧪 #mevosky
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 02/09/2025
The ProSE seminars are back after a summer break. The next speaker is Nir Ben-Tal on "Contrastive learning unites sequence and structure in a global representation of protein space". Date: September 9 Time: 5pm CET Register here: tinyurl.com/prose-seminar2 Please share! 🧪 #mevosky
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