iiinova — where your digital self keeps evolving

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The Lancet @thelancet.com · 09/07/2026

Chronic kidney disease (#CKD) affects 788–844 million adults worldwide — and is projected to become the fifth leading cause of death by 2040. A Lancet Series examines what is needed to change this trajectory: spkl.io/633227Gj1s #ERA2026

Figure showing complex and inter-related social determinants contribute to the rising burden of kidney disease. CKD=chronic kidney disease AKI=acute kidney injury. AKD=acute kidney disease. WASH=water, sanitation, and hygiene. Copyright: 2026 Elsevier Ltd. All rights reserved.

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Journal of Clinical Investigation @jci.org · 04/04/2026

Bariatric surgery in T2D/obesity can improve kidney outcomes @miktmc.bsky.social @kidney-resrch-inst.bsky.social explore structural & transcriptomic changes in kidneys of obese youth with T2D after vertical sleeve gastrectomy, revealing targets for intervention: doi.org/10.1172/JCI1...

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markusathome @markusathome.bsky.social · 05/09/2025

It's Congress-Update time! Check out our new webinar "Post ESC 2025"! youtu.be/6C6lJWUHlc8?...

youtu.be

Post ESC 2025

YouTube video by MARKUS at HOMe

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ASN Publications @asnpublications.bsky.social · 24/08/2025

New in #ASNJASN: Remote volume monitoring in heart failure has big potential. Implantable hemodynamic sensors offer early, actionable data vital for patients with kidney diseases. kidney.pub/JASN0843

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markusathome @markusathome.bsky.social · 05/08/2025

Kidney function trajectories before and after hospitalization for HFrEF by Drs. Kobayashi, Girerd et al. academic.oup.com/eurheartj/ar... In HFrEF, kidney function decline may precede a HF events by up to one year. Monitoring eGFR slopes may allow early detection of patients at risk.

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NEJM.org @nejm.org · 04/08/2025

Today at #WTC2025: A patient with type 1 diabetes underwent transplantation of genetically modified allogeneic islet cells with no immunosuppression. The results of this study support the concept of immune evasion by these modified cells. Read the Brief Report: nej.md/3TXVgwp @ttsorg.bsky.social

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Daniel Drucker @danieljdrucker.bsky.social · 31/07/2025

SURPASS CVOT #T2D #Tirzepatide Non inferior but numerically superior for some endpoints #CVD investor.lilly.com/news-release...

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ASN Publications @asnpublications.bsky.social · 16/07/2025

Could gene-targeted therapy be coming for autosomal dominant polycystic kidney disease? Farabursen, a new medication acquired by Novartis offers to potentially impact cyst formation and even regression. kidney.pub/KN1707-07 #ASNKidneyNews @nephrosparks.bsky.social

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Brendon Neuen @brendonneuen.bsky.social · 15/07/2025

SGLT2i in CKD: impact beyond kidneys 🔻 15% all-cause hospitalizations ✅ Consistent regardless of eGFR, UACR & diabetes 🏥 ~36 fewer hospitalizations per 1000 pt-years Large absolute gains for patients & health systems Meta-analysis in @asnpublications.bsky.social journals.lww.com/cjasn/pages/...

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ASN Publications @asnpublications.bsky.social · 19/07/2025

Mechanistic target of rapamycin (mTOR) inhibitor–based immunosuppression was associated with an improved T-cell response to vaccination in kidney transplant recipients. Read more in #ASNJASN: kidney.pub/JASN0716 @chengshengchai.bsky.social @griffithperkins.bsky.social

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American Journal of Kidney Diseases @ajkd.bsky.social · 18/07/2025

Uromodulin and Risk of Upper Urinary Tract Infections: A Mendelian Randomization Study bit.ly/Liyanarachi2... #OpenAccess #VisualAbstract

bit.ly

Uromodulin and Risk of Upper Urinary Tract Infections: A Mendelian Randomization Study

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NEJM.org @nejm.org · 13/07/2025

In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone production, and hypokalemia. Full SPARK study results: nej.md/40Js1kz #ENDO2025

A figure showing the changes from baseline in systolic blood pressure (SBP), plasma aldosterone–renin ratio (ARR), and serum potassium level for each patient.

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Anand Vaidya @anandvaidya17.bsky.social · 15/07/2025

New Primary Aldosteronism Guidelines - simpler, streamlined, and hopefully more pragmatic academic.oup.com/jcem/advance...

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Joel Topf @kidneyboy.bsky.social · 23/06/2025

This is new. Higher vitamin D levels associated with higher prostate cancer prevalence 🤦🏻‍♂️ I'm sure the "taking vitamin D couldn't hurt" crowd will have an explanation forthcoming

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American Journal of Hypertension @amjhypertension.bsky.social · 22/06/2025

Using an MRA empiricially or renin-guided therapy in apparent treatment resistant hypertension? academic.oup.com/ajh/article/... #WeekendReads from the #EditorsChoice archives

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markusathome @markusathome.bsky.social · 13/06/2025

The 62nd ERA congress Allstars: Late-breaking studies 2025 Our guests: @lonniepyne.bsky.social @lastwalsh.bsky.social Vianda Stel Fadi Fakhouri Hans Mann Natalie Staplin Jonathan Barratt @rosertorra.bsky.social @katestevens.bsky.social youtu.be/HbUEh8oLB2M?...

youtu.be

62nd ERA Congress - Profs. L. Pyne, F. Fakhouri, M. Walsh, H. Mann, N. Staplin, V. Stel & J. Barratt

YouTube video by MARKUS at HOMe

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Alan Jagolinzer @jagolinzer.bsky.social · 12/05/2025

"The perfect storm to support the darkest forces. ...If we don’t engage this crisis with the courage of those who fought on this continent in WW2, then I sense we risk the eventual ramp up to carnage that could easily surpass that." Speech to legislators yesterday. www.linkedin.com/pulse/addres...

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ISNkidneycare @theisn.org · 09/05/2025

📖 This weekend don't miss our @kireports.bsky.social #ISNFridaySelection: Open-Label, Randomized, Controlled, Crossover Trial on the Effect of Dapagliflozin in Patients With ADPKD Receiving Tolvaptan www.kireports.org/ar...

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The New Yorker @newyorker.com · 19/04/2025

Fascism is now in the algorithms, the neural pathways, the social interactions. How did we fail to see all this? “We wanted to see Trump in terms of his absences, so that our way of seeing the world would go unchallenged,” Timothy Snyder writes.

newyorker.com

What Does It Mean That Donald Trump Is a Fascist?

Trump takes the tools of dictators and adapts them for the Internet. We should expect him to try to cling to power until death, and create a cult of January 6th martyrs.

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JoJo CIWA Protocol @jojociwaprotocol.bsky.social · 19/04/2025

sodium 129, patient asymptomatic. please advise

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NEJM.org @nejm.org · 18/04/2025

For patients with lupus nephritis, a recent phase 2 trial showed that the addition of obinutuzumab to standard therapy was associated with a significantly better renal response than placebo. Findings of the REGENCY phase 3 trial are summarized in a new Quick Take video. youtu.be/cqu42EDvPq8 #MedSky

youtu.be

Obinutuzumab in Lupus Nephritis (REGENCY trial) | NEJM

YouTube video by NEJM Group

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markusathome @markusathome.bsky.social · 11/04/2025

Our new webinar in german language: SGLT-2 Inhibitoren & Nierensteine: SWEETSTONE - Prof. D. Fuster, Prof. S. Trelle (Bern, Schweiz) WATCH NOW: youtu.be/i_YTcIQ4YQk?... @danfuster.bsky.social @gunnarheine.bsky.social @marcussaemann.bsky.social

youtu.be

SGLT-2 Inhibitoren & Nierensteine: SWEETSTONE - Prof. D. Fuster, Prof. S. Trelle (Bern, Schweiz)

YouTube video by MARKUS at HOMe

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Joel Topf @kidneyboy.bsky.social · 11/03/2025

But if the rapid rate of correction is actually due to an underlying diagnosis, like beer drinker potomania, then perhaps the ODS is due to the alcoholism, the concurrent hypokalemia, or hypophosphatemia rather than the rate of correction (all of which are actual risk factors for ODS)

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ASN Publications @asnpublications.bsky.social · 05/03/2025

Dapagliflozin improves estimated CVD and ESKD risk in T1D participants, emphasizing the need for cardiorenal outcome trials in people living with T1D. bit.ly/CJASN0641 #ASNCJASN

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markusathome @markusathome.bsky.social · 24/01/2025

Join our new webinar NOW on YouTube! Nephroprotection 2025: "4 Pillars" & EASi-KIDNEY with our guests Dr. Doreen Zhu & Dr. Parminder Judge youtu.be/cpAel7yCW6I?... Moderators: Prof. Dr. Johannes Mann, @gunnarheine.bsky.social @marcussaemann.bsky.social

youtu.be

Nephroprotection 2025: "4 Pillars" & EASi-KIDNEY - Dr. Doreen Zhu & Dr. Parminder Judge (Oxford, UK)

YouTube video by MARKUS at HOMe

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Gunnar Heine @gunnarheine.bsky.social · 03/01/2025

Heute 19:15 Teil 1 der @markusathome.bsky.social Top 12 Nephro youtu.be/D7UeaO6dLZQ?... Partner @oegn.bsky.social DGfN @sfndt.bsky.social Gäste T. Speer, M. Girndt, M. Abu Tair Hosts @sarahelena.bsky.social @kronbichlerlab.bsky.social @marcussaemann.bsky.social M. Antlanger I. Emrich C. Schneppe

youtu.be

Nephrologie / Hypertensiologie 2024 I

YouTube video by MARKUS at HOMe

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markusathome @markusathome.bsky.social · 02/01/2025

We want to thank our 5000 Followers on our YouTube channel MARKUS@HOMe. It's been an honor streaming for you all these years! youtu.be/2gla5f78Mxo?... @gunnarheine.bsky.social @kronbichlerlab.bsky.social @marcussaemann.bsky.social @sarahelena.bsky.social @dguerrot.bsky.social

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Joel Topf @kidneyboy.bsky.social · 25/01/2022

Any good data on hyponatremia in ESRD getting rapid increases in Na during hemodialysis. Interested in neurologic outcomes/development of ODS. #AskRENAL

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Juan Carlos Q Vélez, MD @juancarlosqvelez.bsky.social · 26/11/2024

White blood cell casts in the #UrinarySediment of a pt with C3 glomerulonephritis. Results of the VALIANT trial recently presented at #KidneyWk late-breaking trials suggest that pegcetacoplan may be a game changer for this hard-to-treat condition.

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Gunnar Heine @gunnarheine.bsky.social · 23/11/2024

Es sind solche Kommentare, die selbst nach langer Arbeitswoche uns immer wieder motivieren, weiter für unsere Kollegen zu streamen 😉 @kronbichlerlab.bsky.social @marcussaemann.bsky.social @sarahelena.bsky.social youtu.be/au34nkuDhSM?...

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Gunnar Heine @gunnarheine.bsky.social · 23/11/2024

17.01.2025 Frankfurt Wir laden herzlich zu "MARKUS at HOMe Unplugged 2025" ein! Fortbildungspunkte sind bei der Hessischen ÄK beantragt; die Teilnahme ist gebührenfrei. Vorherige Anmeldung ist erbeten (marion.schirmeister@agaplesion.de) www.youtube.com/watch?v=s3tr... @marcussaemann.bsky.social

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