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Marc Bonten

@marcbonten.bsky.social
2.8K followers 409 following 113 posts

Vice-Dean of education & Professor of Molecular Epidemiology of Infectious Diseases @UMCUtrecht. All opinions my own.

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Marc Bonten @marcbonten.bsky.social · 23/09/2026
When is evidence good enough? Based on the results of the SNAP study: when do you adjust antibiotic prescribing practices? Read my blog that ends with a poll. Interested to see your thoughts on this. mbonten.substack.com/p/when-is-ev...
mbonten.substack.com
When is evidence good enough?
When are you, as a physician, sufficiently convinced by the results of scientific research to change your clinical practice?
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Aliëtte Jonkers @aliettejonkers.nl · 15/07/2026
Van elke “mislukte” studie zou de oorzaak onderzocht en gedeeld moeten worden. Daarmee kunnen onderzoekers toekomstig onderzoek beter voorbereiden, aldus @marcbonten.bsky.social over het onderzoek naar geitenhouderijen en longontstekingen. mbonten.substack.com/p/over-de-ko...
mbonten.substack.com
Over de kool en de geit
Reactie op artikel in NRC
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Ecraid @ecraid.bsky.social · 18/06/2026
📣 Practice-changing data published in both the NEJM and The Lancet! The #SNAPTrial results are set to redefine international guidelines for treating golden #Staph bloodstream infections. Ecraid is proud to be a European partner for this landmark study. #PatientSafety #AdaptiveTrials #StaphAureus
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Marc Bonten @marcbonten.bsky.social · 03/06/2026
Leuk, en ook een heel goeie voetbalfilm vind "the damned United" over de 44 dagen dat Brian Clough manager van Leeds United begin jaren 70.
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Marc Bonten @marcbonten.bsky.social · 03/06/2026
Wellicht interessant. Regelmatig schrijf ik met FritsRosendaal n kort stukje over wat ons opvalt aan de #parlementaire #enquete over #corona; over sluiten van scholen, experts, tijdstip van lockdown, enz Frits, Marc en de enquete Te volgen via 👇 substack.com/home/post/p-...
substack.com
Frits, Marc en de enquête (#4): Alle scholen dicht
Veel aandacht voor onzekerheid in de vroege fase van de pandemie tijdens de eerste dagen van de enquête.
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Angela Huttner @angelahuttner.bsky.social · 17/05/2026
Doing some final editing on next #Communicable ep & found spot where @marcbonten.bsky.social tells us how the FAST RCT got a waiver of informed consent. Anne-Grete and I start dreaming here: our countries would not let us do this. Vanderbilt is a learning health system w/ ethics oversight.🤩 #IDSky
Anne-Grete Märtson, Erin McCreary, Josh Davis, Angela Huttner, and Marc Bonten on a screen having an online conversation about trials.
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CMI Communications @cmicomms.bsky.social · 14/05/2026
📣 New #Communicable drops Mon, 18 May! Our editors - Erin McCreary, PharmD, Josh Davis, Marc Bonten, Anne-Grete Märtson, Angela Huttner - discuss some of the Late Breaker trials that caught their attention at #ESCMIDGlobal2026, and whether results will change their practice🎙️ #IDSky #clinmicro
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Marc Bonten @marcbonten.bsky.social · 09/05/2026
Crying over spilt milk? (mosterd na de maaltijd) Published: the results of ivermectin for acute COVID-19 in the REMAP-CAP study. Enrollment started in June 2021. Effective treatments (#corticosteroids and IL-6 inhibition) were used and vaccination was rolled out. journals.lww.com/ccmjournal/f...
journals.lww.com
Ivermectin for Critically and Noncritically Ill... : Critical Care Medicine
between June 11, 2021, and September 9, 2022. Patients: Critically and noncritically ill patients. Interventions: Randomized to ivermectin or no ivermectin (control). Measurements and Main Resu...
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Marc Bonten @marcbonten.bsky.social · 29/04/2026
The downside of pragmatism: low adherence to study protocol (i.e. fear of aminoglycosides among non-study group members) combined with low enrollment. Lessons learned will be published separately, soon.
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Marc Bonten @marcbonten.bsky.social · 20/04/2026
Waldorf and Statler enjoying the “trial run to non-inferiority” session at ESCMID Global 2026, remembering the times of superiority. @cmicomms.bsky.social @angelahuttner.bsky.social @absteward.bsky.social
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Prof Gavin Yamey MD MPH @gavinyamey.bsky.social · 06/02/2026
🇩🇰📰 If there are any kind Danes who have access to this newspaper, Weekendavisen, & might be willing to send me the piece (which I will Google translate!), I’d be eternally grateful www.weekendavisen.dk/opinion/fagl...
weekendavisen.dk
Faglig uenighed er ikke uredelighed
Debat. Weekendavisen får kritik fra en lang række professorer og lektorer for dækningen af sagen om forskerne Christine Stabell Benn og Peter Aaby.
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Marc Bonten @marcbonten.bsky.social · 06/02/2026
Read my post 👇 substack.com/profile/1201...
substack.com
Marc Bonten (@marcbonten1)
The placebo effect explained? I was alerted to this message in Medisch Contact, a Dutch journal for physicians: “Brain training enhances immune response after vaccination; possible benefit of posi...
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Marc Bonten @marcbonten.bsky.social · 29/01/2026
Published 🎉 Excess mortality during the COVID-19 pandemic partly exceeded COVID-19-related deaths, indicating that other causes (vaccine?) may have contributed. link.springer.com/article/10.1...
link.springer.com
COVID-19 vaccination and short-term mortality risk: a nationwide self-controlled case series study in The Netherlands - European Journal of Epidemiology
Excess mortality during the COVID-19 pandemic partly exceeded COVID-19-related deaths, indicating that other causes may have contributed. We conducted a retrospective data-linkage study including all ...
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CMI Communications @cmicomms.bsky.social · 11/12/2025
📣 New #Communicable drops Mon 15 Dec! @angelahuttner.bsky.social & @marcbonten.bsky.social invite Ilan Schwartz @germhuntermd.bsky.social , Neil Stone @drneilstone.bsky.social & Tara Smith @aetiology.bsky.social to debate staying on or leaving Twitter for alternatives 🎤 #IDTwitter #IDSky #clinmicro
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Angela Huttner @angelahuttner.bsky.social · 26/11/2025
Wait, Marc, I've got a screenshot that includes Tara @aetiology.bsky.social (although we're down to half of @germhuntermd.bsky.social, sorry!). Was a great discussion but I hope we didn't pile on @drneilstone.bsky.social too much... Luckily he was tough and gracious at the same time. #IDSky #MedSky
A screenshot of three guests (Ilan Schwartz, aka GermhunterMD, Neil Stone, and Tara Smith) and two hosts (me & Marc Bonten) of an upcoming episode on whether medical 'influencers' should stay at X or leave it.
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Marc Bonten @marcbonten.bsky.social · 25/11/2025
We recorded a next episode of communicable - podcast from @cmicomms.bsky.social - on "whether to stay or leave twitter/X" with @germhuntermd.bsky.social (40K followers, he left), Neil Stone (115.694, still there) and @aetiology.bsky.social (111.492, still there). (1/) @angelahuttner.bsky.social
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Ecraid @ecraid.bsky.social · 12/11/2025
We are very pleased to announce Lennie Derde as Ecraid's new Chief Executive Officer effective 1 January 2026. She will succeed Ecraid’s co-founder @marcbonten.bsky.social Read more 👉 ecraid.eu/articles/len... @umcutrecht.bsky.social @ec.europa.eu @horizoneu.bsky.social
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Marc Bonten @marcbonten.bsky.social · 04/11/2025
💉 Read my latest science blog on non-specific effects of BCG, a vaccine intended to prevent tuberculosis. 👇 letstalkscience.eu/2025/11/04/l...
letstalkscience.eu
Lost in translation over BCG vaccination - Let's Talk Science with Marc Bonten
Last week I engaged in a discussion on X about the validity of this recent publication on a randomized controlled trial (RCT) on neonatal mortality in newborns. As a background: BCG vaccination is rou...
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Marc Bonten @marcbonten.bsky.social · 11/09/2025
We actually discovered over-the-counter selling of antibiotics @cmicomms.bsky.social
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Marc Bonten @marcbonten.bsky.social · 10/09/2025
Now online: our commentary on the topic of initial antibiotic therapy in patients hospitalized with pneumonia. 👇 💣 Spoiler alert: we need to change rules if we want the best therapy for our patients. www.clinicalmicrobiologyandinfection.org/action/showP...
clinicalmicrobiologyandinfection.org
Empiric antibiotics for moderate-severe community-Acquired Pneumonia: We ought to serve patients better!
Each day thousands of patients are hospitalized worldwide with Community-Acquired Pneumonia (CAP), either radiologically confirmed or presumed based on clinical symptoms only, and each day physicians ...
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Marc Bonten @marcbonten.bsky.social · 18/08/2025
Can acute COVID-19 awaken dormant cancer cells? An important study, recently published. My blog on the translation of experimental findings in mice to observational population-based data in men. 👇 letstalkscience.eu/2025/08/18/c...
letstalkscience.eu
Can acute COVID-19 awaken dormant cancer cells? - Let's Talk Science with Marc Bonten
Yes, according to this study, which was the talk of the summer. In short: In mice experimental lung infection with SARS-CoV-2 and influenza reactivated dormant breast cancer cells, rapidly leading to ...
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Marc Bonten @marcbonten.bsky.social · 19/05/2025
I"Het is waar dat geen enkel gesprek perfect is en dat er altijd een risico is dat een discussie uit de hand loopt. Daarom is het nodig dat de universiteit zorgt voor ondersteuning om veilige klaslokalen te creëren waarin gepassioneerde docenten en open-minded studenten met elkaar in gesprek gaan."
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Cathy Gao-Howard MD MS @catgaohow.bsky.social · 18/05/2025
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
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Marc Bonten @marcbonten.bsky.social · 19/05/2025
Now out: complete analysis of the immune modulation for acute COVID-19 in REMAP-CAP study. Interleukin-6 receptor antagonists (tozilizumab & sarlilumab) did better than standard of care, interleukin-1 receptor antagonist (anakinra) did not. @lenniederde.bsky.social thorax.bmj.com/content/thor...
thorax.bmj.com
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CMI Communications @cmicomms.bsky.social · 18/05/2025
🎙️ Just published a new #Communicable episode: Communicable E27: Late-breaker trials... Hosted by Marc Bonten @marcbonten.bsky.social Josh Davis @gurujosh.bsky.social Erin McCreary @erinmccreary.bsky.social Emily McDonald @dremilymcd.bsky.social Listen here: #IDSky #Clinmicro #MedSky
share.transistor.fm
Communicable E27: Late-breaker trials at ESCMID Global: Should they change your practice? - part 1
This episode of Communicable takes on a special format where editors of...
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Marc Bonten @marcbonten.bsky.social · 14/05/2025
BumblebeeJoe: the gift that keeps on giving.
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Claudia de Breij @claudiazelf.bsky.social · 11/05/2025
Ik vind deze campagne op zijn minst een broodnodig signaal. Doe mee! actie.degoedezaak.org/petitions/mo...
actie.degoedezaak.org
Teken voor een motie van wantrouwen tegen minister Faber
De ondertekenaars van deze petitie laten zien dat het Nederlandse volk klaar is met een minister die de hand boven het hoofd gehouden wordt om de coalitie bij elkaar te houden. Dit terwijl de minister...
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Paul Belcher FRCP HonMFPH 🇪🇺🇬🇧 @pauljbelcher.bsky.social · 11/05/2025
🏥 1 in 3 doctors in Europe are older than 55. Which countries are most at risk from ageing workforces? 'Poor work-life balance, high administrative burdens, and inadequate pay in some countries drive younger doctors to emigrate or leave the profession altogether.' www.euronews.com/health/2025/...
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Marc Bonten @marcbonten.bsky.social · 09/05/2025
Debated for 40 years: Selective Decontamination of the Digestive tract in ICU patients (antibiotics to prevent ICU-acquired infections). My editorial to Josh Davis @gurujosh.bsky.social and Allen Cheng @peripatetical.bsky.social pro-con in @cmicomms.bsky.social. www.cmi-comms.com/article/S295...
cmi-comms.com
The Frank-Starling law of Selective Digestive Decontamination
More than hundred years ago a series of experiments demonstrated that increased strechting of heart muscles (through higher venous return) increased stroke volume (cardiac output). But not endlessly, ...
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Edward Nirenberg @enirenberg.bsky.social · 30/04/2025
Critical new piece from @helenbranswell.bsky.social. This is a crisis point in vaccine regulation.
statnews.com
8 possible indicators of how RFK Jr.’s HHS will handle vaccine policy
Here are eight possible indicators of how health secretary Robert F. Kennedy Jr. may handle U.S. vaccine policy in coming weeks.
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Ben Collins @bencollins.bsky.social · 23/04/2025
RFK Jr.: The teen cum is insufficient. I need more teen cum.
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Ali Messer @freereed59.net · 21/04/2025
www.theguardian.com/commentisfre... we need to ensure these views do not gain traction in the UK
theguardian.com
RFK’s statements prove autistic people and their families everywhere should fear Trump and his allies | John Harris
The idea that autism is some aberration that can be cured is typical of a movement that celebrates simplistic thinking and loathes human difference, says Guardian columnist John Harris
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รค๓คภtђค ๒єฬเtςђє๔ 🏳️‍⚧️ @samanthahoriz0n.bsky.social · 21/04/2025
Well that was fast, Bluesky 🤦‍♀️
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Marc Bonten @marcbonten.bsky.social · 21/04/2025
Trump administration now after editors of medical journals….
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Paul Belcher FRCP HonMFPH 🇪🇺🇬🇧 @pauljbelcher.bsky.social · 20/04/2025
“What is happening now is not normal politics. We’re seeing an assault on the fundamental institutions of our civic life, things we should all swear loyalty to — Democrat, independent or Republican. It’s time for a comprehensive national civic uprising” #HandsOff www.nytimes.com/2025/04/17/o...
nytimes.com
Opinion | What’s Happening Is Not Normal. America Needs an Uprising That Is Not Normal. (Gift Article)
It will take a concerted effort by every sector of our society to respond to Trumpism’s threat.
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Marc Bonten @marcbonten.bsky.social · 21/04/2025
Excellent 🧵debunking the 5 “facts” of the lab-leak theory, now the official thruth according to the White House.
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Alt CDC (they/them) @altcdc.altgov.info · 21/04/2025
HHS Eliminated Programs - Updated Here is an updated list of all programs eliminated in the 2026 HHS Budget. Reach out if you have information or clarity on the cuts. These cuts will impact Every Single American. Email altcdc1@pm.me for PDF and xlsx.
A list of all  agencies and programs the Trump administration is seeking to eliminate. An accessible PDF is available from altCDC. Email altcdc1@pm.me.
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Marc Bonten @marcbonten.bsky.social · 13/04/2025
Now on stage #ESCMIDGlobal2025 dr Cristina Prat presenting data from the ongoing PNEUMO study that aims to quantify the seroprevalence of pneumococcal pneumonia and invasive disease. @ecraid.bsky.social @umcutrecht.bsky.social
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Marc Bonten @marcbonten.bsky.social · 13/04/2025
Nice to see the results from the @ecraid.bsky.social POS-cUTI presented by Chantal Kats, treatment duration of complicated UTI is very heterogeneous and some baseline characteristics are prognostic for durations of >14 days. Results from 1st 1000 patients, currently >3000 in the study.
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Marc Bonten @marcbonten.bsky.social · 13/04/2025
This day is great, even though it just started. I'm still on X (no longer posting) and I had 1 new follower (since weeks): Stevie Nicks! Enjoy the day. www.youtube.com/watch?v=XYgL...
youtube.com
Stevie Nicks - Sara (Live In Chicago)
YouTube video by Stevie Nicks
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Erin McCreary, PharmD @erinmccreary.bsky.social · 12/04/2025
@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025 fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA
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Marc Bonten @marcbonten.bsky.social · 12/04/2025
Excellent presentation by Vitoria Colizza on the role of school closures during the pandemic at @escmid.bsky.social Global2025. For the Netherlands: 5 yrs after the fact I am less convinced that closing schools during the first wave was a stupid thing to do.
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Ecraid @ecraid.bsky.social · 11/04/2025
👉🏽We’re all set and can’t wait to connect with you at ESCMID tomorrow! Find us at Booth E70 in Hall B! Don’t miss out on some great sessions, such as: 🔎 14.45-15.45: Macrolides in community-acquired pneumonia: therapeutic necessity or path to overuse? Co-chaired by our CEO, @marcbonten.bsky.social
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Marc Bonten @marcbonten.bsky.social · 11/04/2025
We must do better in trauma surgery instead of seat belts.
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Marc Bonten @marcbonten.bsky.social · 11/04/2025
I’m in Austria
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Ecraid @ecraid.bsky.social · 10/04/2025
👉🏽‘'Why We Need Warm-Based Networks’' is the topic presented today by Marc Bonten, Ecraid’s CEO at the ICPM Conference. 🔍Are you interested in knowing more about the benefits of a warm-base network over conventional site selection methods? 📄 Download Ecraid’s whitepaper bit.ly/warmbasenetw...
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Ecraid @ecraid.bsky.social · 08/04/2025
#LongCOVID #ClinicalResearch #MedicalResearch #Healthcare #PublicHealth #RemoteTrials #ResearchSky #ScienceSky #AcademicSky @umcutrecht.bsky.social @postcovidnl.bsky.social @longcovidnederland.bsky.social
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Marc Bonten @marcbonten.bsky.social · 06/04/2025
🤮More Vitamin A!
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Ecraid @ecraid.bsky.social · 02/04/2025
Respiratory infections like #COVID place a huge strain on healthcare systems worldwide. The EU-funded #ECRAIDPrime study is exploring potential treatments for viral respiratory infections through a first-of-its-kind #adaptiveplatformtrial in primary care. Read more on www.ecraid.eu/news/ecraid-...
ecraid.eu
ECRAID-Prime Welcomes Georgia: Latest Study Milestones & Updates | Ecraid
The study’s newest country enrols its first patient
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Marc Bonten @marcbonten.bsky.social · 01/04/2025
eur06.safelinks.protection.outlook.com?url=https%3A...
eur06.safelinks.protection.outlook.com
Ecraid (@ecraid.bsky.social)
👋🏽Hello BlueSky! We're excited to join & connect with the community. We'll be sharing updates on how we commit to advance clinical research on infectious diseases & connect with scientific experts! ...
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