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Allen Cheng

@peripatetical.bsky.social
1.1K followers 99 following 45 posts

Infectious diseases physician, epidemiologist. Melbourne, Australia.

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Allen Cheng @peripatetical.bsky.social · 13/04/2025
Congratulations to Steve Tong, Josh Davis and the huge SNAP team (including Monash Health). Clear outcome that cefazolin is less nephrotoxic than flucloxacillin for MSSA, and pencillin is better for PSSA. @steventong.bsky.social @gurujosh.bsky.social
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BK. Titanji @boghuma.bsky.social · 01/03/2025
Cool paper from Florian Kramer & colleagues about a novel feature of circulating H5N1 clade 2.3.4.4. These viruses have a longer stalk in their neuraminidase (NA) enzyme, a key viral protein. This was not seen in past H5N1 strains (2002-2019) Why does it matter?🧪 journals.asm.org/doi/10.1128/...
journals.asm.org
Clade 2.3.4.4b H5N1 neuraminidase has a long stalk, which is in contrast to most highly pathogenic H5N1 viruses circulating between 2002 and 2020 | mBio
While the truncated version of the N1 neuraminidase stalk domain may be associated with increased virulence in poultry, the long version of the stalk domain has been associated with increased transmis...
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Allen Cheng @peripatetical.bsky.social · 02/03/2025
Looks like PubMed is down - not sure if this is a temporary outage or something more sinister. Europe PMC is an alternative search engine for medical literature that is publicly accessible. europepmc.org
europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
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Josh Davis @gurujosh.bsky.social · 12/12/2024
Great list @absteward.bsky.social! Mine is coming soon (limited to 10)
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Allen Cheng @peripatetical.bsky.social · 12/12/2024
Paul Sax's "oh wow" moments in HIV: AZT during pregnancy reduces vertical transmission; triple ARVs improve survival; integrase inhibitors as effective salvage therapy; PrEP is very effective; undetectable = untransmissible and now 6 monthly lenacapravir PReP is 100% effective
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Allen Cheng @peripatetical.bsky.social · 01/12/2024
Five years ago (1 Dec 2019), the first person became unwell in a case cluster of a new infection that we now know as COVID-19. pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV). We report the epidemiological, clinical, laboratory, and radiologica...
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Allen Cheng @peripatetical.bsky.social · 21/11/2024
Congratulations to the BALANCE group on the trial published in NEJM today. This trial tested 7 vs 14 days of antibiotics for bloodstream infection. #IDSky www.nejm.org/doi/full/10....
nejm.org
Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections | NEJM
Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...
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Sonia Koning @sonkoning.bsky.social · 15/11/2024
Lessons from practice for immunocompromised hosts by Dr Ai Li Yeo and A/Prof Claire Dendle #ForbesWeek #IDSky 1. There can be more than two pathologies in immunocompromised patients
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Allen Cheng @peripatetical.bsky.social · 16/11/2024
Allen Yung's Golden Rules of ID. Copied over from the Other Place for @kottonnelson.bsky.social #IDSky
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