iiinova — where your digital self keeps evolving

Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 12/02/2026

Join on zoom! Today at 4PM ET. temple.zoom.us/j/99060976097

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 14/12/2025

My tracing is lousy, but these panels are shifted and slightly rotated.

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Reposted by Lyle W. Ostrow MD PhD

Alexandra Whiteley @alexwhiteley.bsky.social · 23/10/2025

I'm so excited to see this Perspective with @jasonsynaptic.bsky.social out in Neuron! About 8% of our genome is made up of the remnants of LTR-containing retroelements - here, Jason and I explore the activities of retroTEs in neurological health and disease! authors.elsevier.com/c/1lzTx3BtfH...

authors.elsevier.com

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 07/07/2025

While it wouldn't seem surprising if this is happening, the recent Nikkei "investigation" article about it (below) is un-sourced and filled with anonymous quotes. I tried searching myself and only found those same couple papers on arxiv, none on medrxiv or biorxiv. asia.nikkei.com/Business/Tec...

asia.nikkei.com

'Positive review only': Researchers hide AI prompts in papers

Instructions in preprints from 14 universities highlight controversy on AI in peer review

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 19/06/2025

Listener effort measures clinically meaningful change of dysarthria in amyotrophic lateral sclerosis url:https://academic.oup.com/braincomms/article/doi/10.1093/braincomms/fcaf232/8161195 #BetterTogether #EndALS

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Reposted by Lyle W. Ostrow MD PhD

Carlos Brody @carlosbrody.bsky.social · 08/05/2025

we're crowd-sourcing a searchable repository of tangible benefits stemming from federally-funded research. Come enjoy the great stories; or send in an idea; or volunteer to join the team. publicusaresearchbenefits.com please share and re-share so we get more great stories in there!

publicusaresearchbenefits.com

Searchable database of tangible benefits that federally-funded research gave us.

A crowd-sourced site. Health and Well-being. National Security. Prosperity.

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Reposted by Lyle W. Ostrow MD PhD

Les Turner ALS Foundation @lesturnerals.bsky.social · 18/04/2025

When you join the National ALS Registry, you can also join the National ALS Biorepository. Joining is a meaningful way for people with ALS to help in the search for answers. For more information visit cdc.gov/als #ALSRegistry #ALSBiorepository #ALS

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Reposted by Lyle W. Ostrow MD PhD

Stars and Stripes @starsandstripes.bsky.social · 25/04/2025

Nonprofit agencies that assist ALS patients and support research sent a letter to the bipartisan ALS Congressional Caucus after a leaked proposed budget memo from the Health and Human Services Department called for defunding the registry and a biorepository with thousands of lab specimens.

stripes.com

Proposal would defund ALS registry for disease that afflicts veterans at higher rate than general public

Advocates for patients with amyotrophic lateral sclerosis — a fatal condition known as Lou Gehrig’s disease — urged lawmakers to keep funding the National ALS Registry that serves as a centralized dat...

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 01/04/2025

We own several games from www.neurdgames.com and love them all. I just ordered 2 copies of this new one and can't wait to play!

neurdgames.com

GAMES | Neurd Games

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 15/03/2025

I just checked the wayback machine. It looks like that goofy icon of a flag with the wrong number of white "stars" and stripes has actually been used on these websites for many years. Still seems wrong though.

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Reposted by Lyle W. Ostrow MD PhD

ALS United Greater New York @alsofgny.bsky.social · 13/03/2025

URGENT: Protect #ALS Research Funding! Congress may slash CDMRP funding in the CR, halting critical ALS research. ALS cases could rise 70% by 2030, & veterans face 2x the risk. We must act NOW! Tell your Senators to protect funding! als-ny.org/the-threat-t... #ALSResearch

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Reposted by Lyle W. Ostrow MD PhD

The ALS Association @alsassociation.bsky.social · 10/03/2025

We are very concerned about the proposed budget cuts at the NIH and the DOD that could impact ALS research. Our Board of Trustees and staff are taking to Capitol Hill on Wednesday to urge Congress to continue to fund ALS research.

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Reposted by Lyle W. Ostrow MD PhD

Kristin Anderson, PhD @immunegirl.bsky.social · 10/03/2025

A vote for this legislation is a vote to cut federally funded cancer research. Please take action today to ask Congress to vote no on the CR and instead approve a full-year FY25 Defense Appropriations Act that fully funds the OCRP and CDMRP. www.votervoice.net/Shares/B0Y6T...

votervoice.net

Oppose 57% Cut to Congressionally Directed Medical Research Programs Vote NO on the FY25 Continuing Resolution

As early as this Tuesday, the House will be voting on a continuing resolution to fund government programs through the end of fiscal year 2025 (FY25). The proposed legislation, introduced in the House,...

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 10/03/2025

WOW. This is absolutely remarkable work!

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 08/03/2025

Thank you for the quick response! He comes home next Friday for Spring Break and will be in touch and send you his CV then.

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 08/03/2025

Do you have Summer internships for university students? Our son is an Environmental Geoscience major, in his 3rd year at College of Wooster.

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 07/03/2025

Here is a screengrab from Research!America with some of the same info. www.researchamerica.org/marys-letter...

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 07/03/2025

Entire CDMRP FY25 budget may be in jeopardy. Please see below and spread the word. bsky.app/profile/alsa...

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 28/02/2025

Please read this if you want to understand more about how indirect rates are set, and why indirect costs are critical to research. Then, sign the petition linked in the article. #ScienceMatters #BetterTogether

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Reposted by Lyle W. Ostrow MD PhD

iamals.bsky.social @iamals.bsky.social · 24/02/2025

Each year ALS advocates ask Congress to support the federal funding of ALS research through appropriations requests. Help these advocates supercharge their requests in YOUR district by becoming a constituent! iamals.org/action/help-...

iamals.org

Help The Legislative Team - I AM ALS - ALS is Relentless. So Are We!

ALS Advocates! I AM ALS’ Legislative Affairs Community Team needs your help. Every single day, this team reaches out to legislators to convince them to beco ...

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 19/02/2025

From Everything ALS: 🔬 Join us for a free webinar with Dr. Laura P.W. Ranum! 🧠 📅 Date: February 19, 2025 ⏰ Time: 7 PM EDT | 4 PM PDT 📍 Free Online Webinar 📢 Register now and be part of the conversation: everythingals.org/events

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Reposted by Lyle W. Ostrow MD PhD

Katie Langin @klangin.bsky.social · 14/02/2025

Dear federal scientists: If you have been affected by the probationary firings and would be willing to speak with Science, please reach out to me by email (klangin@aaas.org) or on Signal. We can guarantee annonymity.

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 14/02/2025

A new preprint from the smarter Dr. Ostrow (and my date for Valentine's Day).

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 14/02/2025

"GsMTx-4 can reverse hyperalgesia, restoring withdrawal thresholds to baseline levels." @ostrowkimber.bsky.social,

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Reposted by Lyle W. Ostrow MD PhD

Brain @brain1878.bsky.social · 13/02/2025

Using data from the UK Biobank, Yi et al. identify two subtypes of preclinical type 2 diabetes: one with high leptin and BMI, and a greater susceptibility to psychiatric conditions; the other with abnormal glucose metabolism and increased risk of neurodegenerative disorders. tinyurl.com/mudt44kk

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 12/02/2025

Don't feel bad! I've been told it's the path to immortality. 😁

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Reposted by Lyle W. Ostrow MD PhD

Eric Topol @erictopol.bsky.social · 11/02/2025

A Direct Hit, by @holdenthorp.bsky.social @science.org www.science.org/doi/full/10.... "This is a moment to unite."

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Reposted by Lyle W. Ostrow MD PhD

Silas Maniatis @manimota.bsky.social · 10/02/2025

NYGC is organizing a number of efforts to address the changes to NIH IDCs and other changes to federal policy. If you are a US citizen, or in the US working in science, please consider signing this petition. The more signatures the stronger our hand in interacting with law makers. chng.it/kK2HMP5pGk

chng.it

Sign the Petition

Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

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Reposted by Lyle W. Ostrow MD PhD

emptywheel @emptywheel.bsky.social · 09/02/2025

This is critically important. When asked to PROVE the claims that Elon is spewing on Xitter, Trump had nothing. Nothing. Until they present proof, no media outlet should repeat unsubstantiated claim this is about efficiency.

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 05/02/2025

Tomorrow (Thursday) night at 7pm ET!

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Reposted by Lyle W. Ostrow MD PhD

Indy Auntie @indyauntie.bsky.social · 05/02/2025

Spent day with anxious ALS patients, caregivers, and resource providers; scientists who have (had?) pride in U.S. research infrastructure; and grassroots advocates who've achieved impressive results. Money quote: "Patient needs don't change when you strike DEIA language from government websites." 😢

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Reposted by Lyle W. Ostrow MD PhD

Charles Gaba ✡️ @charlesgaba.com · 02/02/2025

📣 UPDATE: OK, still working with some others to figure out the best way to present it all, but in the meantime here's the first batch of links to the most-recent archived versions of every page at the CDC prior to the Trump/Musk Purge: acasignups.net/25/02/02/whi...

acasignups.net

In which I provide links to archived versions of every CDC.gov page available pre-purge (Part 1 of 15)

As horrific as it is that the Trump/Musk Administration is purging data from federal websites, it's good to know that the Internet Archive has been archiving much of it. However, in addition to the Ar...

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Reposted by Lyle W. Ostrow MD PhD

Gary Swergold MD, PhD @gs314.bsky.social · 31/01/2025

🧪 If I were Canadian PM I would immediately: 1. Create a new $15B science fund 2. Offer any credentialed US scientist funding for lab startup and replacement of NIH grants if they move to Canada 3. Immediate permanent residency 4. Citizenship after 2 years Overnight a science superpower

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Lyle W. Ostrow MD PhD @lyleostrow.bsky.social · 29/01/2025

But won't this increase global warming?

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Reposted by Lyle W. Ostrow MD PhD

iamals.bsky.social @iamals.bsky.social · 24/01/2025

The ALS Calendar is intended to be a one-stop shop for ALS-related events of all kinds, from all across the internet. Whether you're a person hosting a local event or an organization putting on a webinar, add it to the ALS Calendar so folks can find them in one place! www.iamals.org/als-calendar/

iamals.org

Events - I AM ALS - ALS is Relentless. So Are We!Event SeriesEvent SeriesEvent SeriesEvent SeriesEvent SeriesEvent SeriesEvent SeriesEvent SeriesEvent SeriesEvent SeriesEvent SeriesEvent SeriesEvent S...

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