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Rick Huganir

@rhuganir.bsky.social
1.9K followers 153 following 46 posts

I am a neuroscientist at Johns hopkins University interested in the molecular mechanisms underlying learning and memory in health and disease.

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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 25/08/2026
"The foundation for who we are is being built long before we ever hear our first sound." - Patrick Kanold, professor of biomedical engineering and neuroscience at @jhu.edu Article Link: www.oneneurojhu.org/2026/08/25/b...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 03/04/2026
The winner of OneNeuro's March #FotoFriday #FluorescenceFriday contest is "Unleash our inner programmers, without AI" submitted by @takualiu.bsky.social in the Marina Bedny Lab @jhuartssciences.bsky.social View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/
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Reposted by Rick Huganir
Amar Sahay @amarsahay.bsky.social · 10/03/2026
Blast from the past: Hopkins relay team w @rhuganir.bsky.social @jasonsynaptic.bsky.social Gavin Rumbaugh
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Reposted by Rick Huganir
Richard Roth @rhroth.bsky.social · 13/03/2026
Finally, I’m deeply grateful to my PhD mentor @rhuganir.bsky.social and my postdoc mentor Jun Ding, as well as all the Huganir and Ding lab members, for many years of great scientific exchange, support, and friendship. Excited to continue this journey in beautiful Toronto! /3
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 10/02/2026
Figure skaters can spin at 300+ times per minute without getting dizzy. Johns Hopkins scientists explain the brain science behind Olympic winter athletes' remarkable abilities. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2026/02/10/t...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 17/02/2026
Computer-based cognitive speed training linked to 25% reduced dementia risk up to 20 years later in NIH-funded study, offering hope for non-drug interventions. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2026/02/17/c...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 06/03/2026
The winner of OneNeuro's February #FotoFriday #FluorescenceFriday contest is "Spatial transcriptomics captures brain regions in the hummingbird bobtail squid" submitted by Alyson Hally in the @loyalgoff.bsky.social Lab at @hopkinsmedicine.bsky.social View BRAINART gallery: www.oneneurojhu.org/art/
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 23/03/2026
"I worry about how poorly science is communicated to the public. There's a huge disconnect, and I think scientists need to do more to humanize what we do and make it accessible." — Blake Creighton, PhD Candidate www.oneneurojhu.org/2026/03/23/o...
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Reposted by Rick Huganir
Tychele Turner @tycheleturner.bsky.social · 07/02/2026
"δ-catenin haploinsufficiency is sufficient to alter behaviors and glutamatergic synapses in mice" www.ibroneuroscience.org/article/S030...
ibroneuroscience.org
δ-catenin haploinsufficiency is sufficient to alter behaviors and glutamatergic synapses in mice
At PSD, the N-cadherin-δ-catenin-ABP/GRIP complex functions as an anchor for GluA2. Heterozygous δ-catenin KO and G34S mice show impairments in social behavior and fear learning and memory. Only KO ha...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 06/02/2026
The winner of OneNeuro's January #FotoFriday #FluorescenceFriday contest is "Electrophysiology of Cultured Neurons" submitted by Madison Yorkowski in the Ali Fatemi Lab at Kennedy Krieger Institute. View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/
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Rick Huganir @rhuganir.bsky.social · 06/02/2026
New Neuroscience Masters Degree at Johns Hopkins The M.S. degree in Neuroscience is a full-time in-person program consisting of intensive coursework followed by 12 months of laboratory research. The application deadline is May 15, and more information is available at neuroscience.jhu.edu/graduate/51
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 29/01/2026
"Choose your training environment carefully. Lab culture and institutional culture will significantly impact your happiness and success, so choose carefully." - OneNeuro Profile: Seth Blackshaw, PhD @sethblackshaw.bsky.social www.oneneurojhu.org/2026/01/29/o...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 27/01/2026
Johns Hopkins scientists discover that brain cells constantly attempt to produce myelin at a steady pace throughout the brain, offering new insights for treating multiple sclerosis. @jhu.edu www.oneneurojhu.org/...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 21/01/2026
"We study human vision, focusing on the neural and computational basis of high-level vision using cognitive and computational neuroscience techniques." — Mick Bonner , PhD @mickbonner.bsky.social www.oneneurojhu.org/2026/01/21/o...
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Reposted by Rick Huganir
Jason Shepherd @jasonsynaptic.bsky.social · 09/01/2026
Study section done. Now can enjoy the PC learning and memory meeting! Looking forward to some stimulating science chats on the ski lift as well this weekend.
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Rick Huganir @rhuganir.bsky.social · 06/01/2026
Rescue of excitotoxicity in a mouse model of a rare neurodevelopmental disorder by ASO treatment.
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Rick Huganir @rhuganir.bsky.social · 02/01/2026
We just posted our new paper, “Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant”. In this paper, we, in collaboration with Shu-Ling Chiu's lab, generated a mouse model of a rare missense mutation in the AMPA receptor GluA1 subunit. www.biorxiv.org/content/10.6...
biorxiv.org
Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant
AMPA receptors (AMPARs) mediate fast excitatory synaptic transmission and are essential for neuronal development and brain function. We investigated the role of a recurrent variant in the AMPAR GluA1 ...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 19/12/2025
The winner of OneNeuro's November #FotoFriday #FluorescenceFriday contest is "Portrait of a Claustrocortical Neuron" submitted by Baldomero B. Ramírez Cantú in the Solange Brown Lab at @hopkinsmedicine.bsky.social View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 07/11/2025
The winner of OneNeuro's October #FotoFriday #FluorescenceFriday contest is "Purkinje cell complex spikes & simple spikes," submitted by Chenhao Bao in the Cullen lab at JHU Biomedical Engineering. @thecullenlab.bsky.social @chenhaobao.bsky.social Complete gallery: www.oneneurojhu.org/art/
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 06/11/2025
Johns Hopkins scientists discover how brain cells form nanotube networks to transport toxic molecules like amyloid-beta between neurons, offering new insights into Alzheimer's disease progression. @hyungbaekwon.bsky.social @hopkinsmedicine.bsky.social @science.org www.oneneurojhu.org/2025/11/06/n...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 23/09/2025
Four @jhu.edu @jhuartssciences.bsky.social faculty members were recently named part of three large-scale, multi-institutional, highly competitive collaborations funded by the @simonsfoundation.org to explore novel areas in established fields. www.oneneurojhu.org/2025/09/23/f...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 06/10/2025
New test detects brain cancers in cerebrospinal fluid with 80% sensitivity and 100% specificity, enabling clinicians to better detect cancer and better understand the disease status, supporting a more tailored approach to patient care. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2025/10/06/t...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 10/10/2025
The winner of OneNeuro's September #FotoFriday #FluorescenceFriday contest is "The Cochlear Constellation," submitted by Yassine Balhi in Amanda Lauer's lab at @hopkinsmedicine.bsky.social. View the complete gallery here: www.oneneurojhu.org/art/
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 15/10/2025
Novel in utero gene therapy shows promise for spinal muscular atrophy, with potential to help babies reach motor milestones previously thought impossible. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2025/10/15/n...
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Rick Huganir @rhuganir.bsky.social · 19/09/2025
I am excited to announce that the Johns Hopkins University Solomon H. Snyder Department has become an interdivisional department between the School of Medicine and the Krieger School of Arts and Sciences, unifying neuroscience research and education across the university. hub.jhu.edu/2025/09/15/j...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 05/09/2025
OneNeuro's August #FotoFriday #FluorescenceFriday contest winner is "Cellular Subtype Composition of an Amphetamine-activated Ensemble in mPFC," by Suhaas Adiraju from @martinowk.bsky.social at the @lieberinstitute.bsky.social View the complete gallery here: www.oneneurojhu.org/art/
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Bita Moghaddam @bita137.bsky.social · 28/08/2025
The statement by Caroline Kennedy about RFK Jr has aged well www.youtube.com/shorts/fm0-a...
youtube.com
Caroline Kennedy calls cousin RFK Jr a 'predator' | ABC NEWS
YouTube video by ABC News (Australia)
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Reposted by Rick Huganir
Kurt Fraser @kurtfraser.bsky.social · 22/08/2025
My hero!!!!
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 20/08/2025
Johns Hopkins scientists discover how a protein organizes message-carrying "bubbles" in brain synapses—advancing understanding of memory formation and learning. www.oneneurojhu.org/... @watanabelab.bsky.social
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Rick Huganir @rhuganir.bsky.social · 19/08/2025
A giant in the field! Gave some of the best talks I have ever seen.
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Reposted by Rick Huganir
Piali Sengupta @senguptalab.bsky.social · 19/08/2025
A legend. Was and am still inspired by his work. Sad to hear this.
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Rick Huganir @rhuganir.bsky.social · 12/08/2025
Go Tricia! Go Hopkins!
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 11/08/2025
We are thrilled to announce that OneNeuro Co-Director Patricia Janak, Ph.D., has been elected as the 2026-2027 President of the Society for Neuroscience (SfN). @janaklab.bsky.social View the official announcement: www.sfn.org/publications...
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Stacy Lu @moxieluhu.bsky.social · 15/07/2025
Well said, Rick. I remember covering your groundbreaking work on SYNGAP many years ago for Monitor on Psychology magazine. I fully hope your research endures.
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University of Maryland School of Medicine @medschool.umaryland.edu · 15/07/2025
🚨 BREAKTHROUGH: UMSOM researchers win $250K NIH prize for tech that delivers CRISPR across the blood-brain barrier. 🧠🧬 Led by Dr. Poulopoulos, the Crisaptics Trans-BBB Team’s work could transform treatment for Huntington’s & glioblastoma. 🔗 bit.ly/44NGUDP #CRISPR #NIH #Neuroscience #MedEd #MedSky
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Reposted by Rick Huganir
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14/07/2025
Dynamic extracellular interactions with AMPA receptors www.biorxiv.org/content/10.1101/202…
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 11/07/2025
The winner of OneNeuro's June #FotoFriday #FluorescenceFriday contest was submitted by Victor Omoniyi at the Marie Hardwick and Lauren Jantzie Laboratories. @johnshopkinsmmi.bsky.social View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 09/07/2025
"Labs like mine, working toward treatments that could transform thousands of lives, are forced to shut down projects, turn away talent, and walk away from cures within reach. It's not abstract. It's not academic. This is real. This is happening now. And it is crushing." tinyurl.com/3vt7wc99
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Rick Huganir @rhuganir.bsky.social · 30/06/2025
In this essay in Hopkins Magazine, I talk about how NIH budget cuts will delay or stop the translation of basic science to the clinic and impact kids with intellectual disability, autism, and epilepsy. hub.jhu.edu/magazine/202...
hub.jhu.edu
Research funding cuts: What's at stake
Researchers like Richard Huganir are closing in on a cure for SYNGAP1-related disorders. But in the face of federal funding cuts, can they finish what they started?
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 26/06/2025
New gene therapy approach targets rare genetic diseases by boosting expression of autism-linked genes. "We stand on the brink of medical breakthroughs—we are so close." @jmcoller.bsky.social www.oneneurojhu.org/2025/06/26/a...
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 18/06/2025
OneNeuro Discovery Awards 2025 announced. Three projects spanning School of Medicine, Krieger School of Arts & Sciences, and Bloomberg School of Public Health: axon research, psilocybin for amblyopia, and mosquito neuroscience View the official announcement here: hub.jhu.edu/2025/06/17/j...
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Reposted by Rick Huganir
ACLU @aclu.org · 16/06/2025
BREAKING: A federal judge reversed National Institutes of Health's terminations of hundreds of critical research grants that were canceled because of their alleged connection to disfavored topics, including diversity, equity, inclusion, and gender identity. This is a major win for public health.
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Ed Twomey @cryoet.bsky.social · 16/06/2025
Here's our new preprint led by @wdhale.bsky.social with @rhuganir.bsky.social: "Architecture, Activation, and Conformational Plasticity in the GluA4 AMPA Receptor" www.biorxiv.org/content/10.1... #iGluRs #cryoEM Some key points below that Dylan discovered:
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Rick Huganir @rhuganir.bsky.social · 10/06/2025
Warning about national brain drain and the end of American Science as we know it. www.nytimes.com/2025/06/03/u...
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Stand Up for Science! @standupforscience.net · 09/06/2025
"It's a horror show. We're under attack in every way all the time," says Sarah Kobrin, who has worked at the National Cancer Institute for more than 21 years. "We're told we're worthless. We're told we're cheats.… They're breaking things that won't be repairable." www.npr.org/sections/sho...
npr.org
NIH scientists call on director to protect biomedical research
In a public letter, hundreds of scientists expressed their dissent to the Trump administration's policies affecting the National Institutes of Health and called on its director to support the agency.
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Walker Bragman @walkerbragman.bsky.social · 10/06/2025
“Bhattacharya later testified before Congress that it – and he – immediately became targets of suppression and censorship by those leading scientific agencies.” This line in CNN’s piece on the Bethesda Declaration is really inexcusable. Bhattacharya was never censored. He took case to SCOTUS & lost
cnn.com
NIH employees publish ‘Bethesda Declaration’ in dissent of Trump administration policies | CNN
Staffers at the US National Institutes of Health published a letter of dissent, taking issue with what they see as the politicization of research and destruction of scientific progress under the Trump...
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Denis Wirtz @deniswirtz.bsky.social · 09/06/2025
The NIH has not issued a single new call for proposals since the end of January.
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Jeremy Berg @jeremymberg.bsky.social · 09/06/2025
I wanted to show support for these brave public servants and to allow others, including the scientific community, to join me. In partnership with @standupforscience.bsky.social‬, we have a way for you to do that... www.standupforscience.net/bethesda-dec...
standupforscience.net
Bethesda Declaration — STAND UP FOR SCIENCE
Support NIH Staff Now!
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Reposted by Rick Huganir
OneNeuro Initiative @oneneurojhu.org · 05/06/2025
As the United States cuts budgets and restricts immigration, China and Europe are offering researchers money and stability. Article Link: www.nytimes.com/2025/06/03/u...
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OneNeuro Initiative @oneneurojhu.org · 04/06/2025
The winner of OneNeuro's May #FotoFriday #FluorescenceFriday contest, "Astrocytes chewing tau aggregates in mouse brain", was submitted by Meghraj Baghel at the Philip C. Wong Lab. View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/
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