Research Assistant I - Molecular & Human Genetics

Reprogramming resident glia into neurons holds great therapeutic promise for neurodegenerative diseases across the central nervous system, yet thes...

Retinal ganglion cells (RGCs) are the sole output neurons of the retina, responsible for transmitting visual information to the brain. Recent transcriptomic studies have revealed extensive molecular d...

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Summary: Temporal disruption of sonic hedgehog signaling reveals stage-specific roles in eye cup patterning and in regulating proliferation, progenitor competence and fate specification during retinal...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Zhang et al. found that two waves of apoptosis occur in developing human retinas and retinal organoids, affecting RPCs and RGCs, respectively. Retinal organoids undergo an additional wave of necrosis ...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Summary The applicant will join the Scalabrino Lab at the Medical College of Wisconsin Eye Institute. The research explores how various blinding diseases change neuronal function of the retina, the li...

Featuring Deepak Lamba, Director and Distinguished Scientist, Ophthalmology, and Susie Crowell, Senior Director, Project Team Leader.

Join Neurogenesis and Repair 2026, July 13-16, 2026. Learn more on Fourwaves.

In the central region of the human retina, the high-acuity foveola is notable for its dense packing of green (M) and red (L) cones and absence of b...

A fundamental role for division orientation in progenitor output driving cortical and retinal growth is revealed.

A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields

The regulatory codes controlling vertebrate retinal gene expression have been conserved over more than half a billion years.

Summary: Modulation of members of the retinal determination gene regulatory network and their co-factors in Drosophila eyes reveals that differential expression of transcription factors is sufficient ...

Circadian photoentrainment depends on intrinsically photosensitive retinal ganglion cells (ipRGCs), which convey environmental light information to th…

The Sonic Hedgehog (Shh) signaling pathway is essential for the patterning, growth, and morphogenesis of many tissues. During early eye development, Shh is critical for the formation of the two optic ...

Dr. Joel Miesfeld’s lab studies the mechanisms behind retinal ganglion cells to better understand vision development.

Biological age is a major risk factor in the development of common degenerative retinal diseases such as age-related macular degeneration and glaucoma. To systematically characterize molecular mechani...

Müller glia are retinal support cells that play crucial roles in tissue structure, waste management, and repair. A challenge for the field has been to find Müller glia markers that detect non-reactive...

Morphogenesis of the anterior segment (AS) is crucial for healthy ocular physiology and vision but is only partially understood. The Schlemm's canal (SC) and trabecular meshwork (TM) are essential dra...

Highlighted Article: Distinct gene sets are differentially expressed in response to the knockdown of Polycomb Group (PcG) members, suggesting that multiple avenues may exist for the eye to be transfor...