Sign in

Revathi Balasubramanian

@ladyglaucoma.bsky.social
724 followers 567 following 47 posts

Assistant Professor of Ophthalmic Sciences @Columbia University, Developmental ocular biology, Mom-scientist, Chai lover, All things women-in-science, Immigrant.

PostsRepliesMedia
Reposted by Revathi Balasubramanian
Flavio Zolessi @fzolessi.bsky.social · 23/06/2026
New preprint! Another piece from @gaparicio.bsky.social thesis, now exploring the role of PALS1 (aka Nok, or MPP5) in lamination and photoreceptor progenitors positioning in the developing zebrafish retina and retinal organoids: tinyurl.com/yya754tf
tinyurl.com
Reduction of PALS1/Nok disrupts retinal lamination through altered cell positioning while preserving photoreceptor self-organization capacity
The vertebrate neural retina is composed of several neuronal types that precisely organize into layers, with photoreceptors facing the outer surface and the projection neurons, retinal ganglion cells,...
1125
Revathi Balasubramanian @ladyglaucoma.bsky.social · 15/07/2026
Feels like someone spied into my life to write this. Hits so close! 😭
020
Reposted by Revathi Balasubramanian
Gretchen Goldman, PhD @gretchentg.bsky.social · 09/06/2026
The strong collective response of the science community to the proposed OMB rule has demonstrated the broad unity that’s possible when we all work together. We'd do well to apply this same level of activation to the larger assaults on science and democracy. My new post: blog.ucs.org/gretchen-gol...
blog.ucs.org
The Science Community Is Stepping Up. Let’s Go Bigger.
The scientific community is fighting a proposed change to research funding. Let's keep this momentum going to take on more attacks on science.
213961
Reposted by Revathi Balasubramanian
Cubical/ Kizhatil @cubical.bsky.social · 08/05/2026
Our new review of #development of the #Schlemm’s canal and implication for #glaucoma treatment is out!!!!! Thanks to my coauthors, Marina Simón, Revathi Balasubramanian @ladyglaucoma.bsky.social and Simon John!!! www.annualreviews.org/docserver/fu...
annualreviews.org
041
Revathi Balasubramanian @ladyglaucoma.bsky.social · 03/05/2026
For me, this signals the start of fun science at #ARVO ❤️
1213
Revathi Balasubramanian @ladyglaucoma.bsky.social · 27/04/2026
I will be at ARVO and have a poster 3006 - 0256, May 5th at 1:15. Hope to connect with you all vision people!
194
Revathi Balasubramanian @ladyglaucoma.bsky.social · 20/04/2026
Honored to receive the @brightfocus.bsky.social National Glaucoma Research Award! Thank you for supporting my lab's work on developmental glaucomas!
1100
Revathi Balasubramanian @ladyglaucoma.bsky.social · 17/04/2026
Congratulations to @mfsd2a.bsky.social and co-authors for this fantastic paper showing elevations in intraocular pressure compromises the blood-retina barrier. Incredible work and opens up a whole new investigative line for glaucoma! www.nature.com/articles/s41...
nature.com
Intraocular pressure induced blood retinal barrier compromise in mouse models and human glaucoma - Nature Communications
Glaucoma is a common cause of vision loss. Here the authors show that elevated intraocular pressure disrupts the blood retinal barrier (BRB) and contributes to retinal ganglion cell death in mouse gla...
050
Reposted by Revathi Balasubramanian
Anna Vlasits @annaintegrated.bsky.social · 16/04/2026
The Vlasits Lab is hiring a technician because our current technician was accepted into a PhD program! This position combines lab management and experiments. If you are interested in gaining experience with #retina research in Chicago, please apply. vlasitslab.org uic.csod.com/ux/ats/caree...
vlasitslab.org
Vlasits Lab
0136
Reposted by Revathi Balasubramanian
Mariko Bennett @nachoriko.bsky.social · 24/03/2026
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
491706568
Reposted by Revathi Balasubramanian
Danny Saban @sabanlab.bsky.social · 24/03/2026
Resident tissue #macrophages (RTM) are now recognized as integral regulators of tissue physiology, not transient immune sentinels. one fundamental question remains unresolved: why do some populations achieve lifelong self-maintenance, while others are replaced under steady-state conditions? 🧵1/11
22711
Revathi Balasubramanian @ladyglaucoma.bsky.social · 13/03/2026
Our recent paper picked up by The Ophthalmologist! www.theophthalmologist.com/issues/2026/...
theophthalmologist.com
Targeting Trabecular Meshwork Metabolism
Study suggests potential new vitamin B3 treatment for glaucoma protection
021
Reposted by Revathi Balasubramanian
Anna La Torre @latorrelab.bsky.social · 09/02/2026
Check out this beautiful new story from @michelcayouette.bsky.social lab!!! We got to play a small part along the way. So thrilled to see this out in the world!
041
Reposted by Revathi Balasubramanian
Michel Cayouette @michelcayouette.bsky.social · 04/02/2026
Happy to announce that our latest paper is now out! Have you ever wondered how neural tissues control their size? In this paper, we show that cell division orientation is critical in both the cortex and retina. www.science.org/doi/10.1126/...
science.org
Oriented cell divisions induce basal progenitors and regulate neural expansion across tissues and species
A fundamental role for division orientation in progenitor output driving cortical and retinal growth is revealed.
59331
Reposted by Revathi Balasubramanian
Seth Blackshaw @sethblackshaw.bsky.social · 12/12/2025
A couple of papers are finally out too. First, Meis factors are (unfortunately) not sufficient to respecify temporal identity in retinal progenitor cells. www.nature.com/articles/s41...
nature.com
Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis - Scientific Reports
The vertebrate retina serves as a model for studying neurogenesis and cell fate specification, with retinal progenitor cells following a tightly regulated temporal sequence to generate distinct cell t...
062
Revathi Balasubramanian @ladyglaucoma.bsky.social · 20/10/2025
This Diwali I am hoping that the good truly does triumph over all evil, and soon. Happy Diwali to those celebrating!
media.tenor.com
a greeting card for happy diwali with fireworks and candles
ALT: a greeting card for happy diwali with fireworks and candles
150
Reposted by Revathi Balasubramanian
Anita Devineni @anitadevineni.bsky.social · 30/09/2025
My department at Emory is a hiring a tenure-track neuroscientist! Anyone who's talked to me in the last 4 years knows I cannot say enough good things about my dept and the neuroscience community here. My colleagues are so wonderfully supportive. Postdocs, please apply! apply.interfolio.com/174371
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
1135104
Reposted by Revathi Balasubramanian
Schallek Lab @schalleklab.bsky.social · 12/09/2025
#FluorescenceFriday Strand and branch pericytes surround the vessels of the retina👁️🔬 color=depth @flaumeye.bsky.social @urneuroscience.bsky.social @cvsuor.bsky.social @uofrbme.bsky.social @urochestersmd.bsky.social
39813
Reposted by Revathi Balasubramanian
Seth Blackshaw @sethblackshaw.bsky.social · 12/09/2025
Our latest manuscript is out, and this one tackles the problem of cellular aging in the retina, using comparative multiomic analysis of zebrafish, mouse, and humans. What led us to work on aging after studying development and regeneration? Explainer follows./1 www.biorxiv.org/content/10.1...
biorxiv.org
Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging.
Biological age is a major risk factor in the development of common degenerative retinal diseases such as age-related macular degeneration and glaucoma. To systematically characterize molecular mechani...
17421
Revathi Balasubramanian @ladyglaucoma.bsky.social · 22/08/2025
Excited to share this study! We created a developmental atlas of the anterior segment of the eye and provide crucial molecular information that guides the development of Schlemm’s canal and trabecular meshwork cell subtypes. www.biorxiv.org/content/10.1...
biorxiv.org
Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm's Canal
Morphogenesis of the anterior segment (AS) is crucial for healthy ocular physiology and vision but is only partially understood. The Schlemm's canal (SC) and trabecular meshwork (TM) are essential dra...
2213
Reposted by Revathi Balasubramanian
Oliver lab @lymphaticsprox1.bsky.social · 31/07/2025
Please repost and share
043
Reposted by Revathi Balasubramanian
BWJones @bwjones.bsky.social · 28/07/2025
The NIH was healthiest when pay lines were in the 20th percentile range. We are headed into an environment where pay lines are in the 5% range. In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one. This is going to destroy science.
1524080
Revathi Balasubramanian @ladyglaucoma.bsky.social · 29/07/2025
Paper alert! With co-first authors Nick Tolman and @taiboli.bsky.social , we profile trabecular meshwork cells using single-cell RNA + ATAC seq, identify mitochondrial dysfunction in an early-onset glaucoma model, and use Vitamin B3 to protect against nerve damage. elifesciences.org/reviewed-pre...
elifesciences.org
Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment
192
Reposted by Revathi Balasubramanian
Michel Cayouette @michelcayouette.bsky.social · 25/07/2025
Hi all, we got a grant for a cool project that will follow up of our paper published a few months ago (see below). We will explore how light acts as a morphogen to instruct PCP. If you are looking for a postdoc position and interested in this topic, please reach out!
02615
Reposted by Revathi Balasubramanian
Michel Cayouette @michelcayouette.bsky.social · 20/06/2025
On Sunday I will cycle 50 km to raise money to support research to prevent blindness. If you can, please sponsor me! fightingblindness.akaraisin.com/ui/MOVEFORSI...
fightingblindness.akaraisin.com
0104
Revathi Balasubramanian @ladyglaucoma.bsky.social · 13/06/2025
In more good new for the lab.. Just heard that we got a grant from The Glaucoma Foundation for our work on early onset glaucomas! Thank you TGF.
1160
Reposted by Revathi Balasubramanian
Tal Nuriel, PhD @talnuriel.bsky.social · 10/06/2025
Ok, that’s it. Here’s the link again: joinus.cuimc.columbia.edu/participant/.... I know there's a lot of chaos right now, and it’s hard to know which crisis to focus your attention on and where to devote your time/resources. So if you decided to support my lab, I really do appreciate it! 9/9
0104
Revathi Balasubramanian @ladyglaucoma.bsky.social · 04/06/2025
Just got word that I got the RPB career development award. It feels weird to be happy when science funding is under attack. But one small win, one more day of science (or 4 more years). Thank you, Research to Prevent Blindness foundation.
7411
Reposted by Revathi Balasubramanian
Paloma Liton @palomaliton.bsky.social · 22/05/2025
🚨 Final Reminder! 🚨 Don't miss your chance to share your research at the ISER BrightFocus Glaucoma Meeting 2025! 📅 Abstract Submission Deadline: May 27, 2025 🔗 iserbrightfocusglaucoma.org/abstract-sub... @iser.bsky.social @brightfocus.bsky.social
iserbrightfocusglaucoma.org
Abstract Submission – Iser/Bright Focus Glaucoma Symposium
076
Reposted by Revathi Balasubramanian
Rejji Kuruvilla @rkuruvi1.bsky.social · 10/05/2025
The pact of the federal govt with universities was not a handout. It was a strategic decision to boost US leadership in technology, defense, and health. And it paid dividends. In tech, internet, in cancer drugs (for example), No other sector has invested in high risk high reward ideas like US govt.
11411116
Reposted by Revathi Balasubramanian
Denis Wirtz @deniswirtz.bsky.social · 07/05/2025
We have updated our database of funding opportunities for Early-Career Researchers (private foundations, federal, international) We have 456 entries, for which we provide $ amount, deadline, eligibility criteria, etc. Download this massive database here for free: research.jhu.edu/rdt/funding-...
3193139
Revathi Balasubramanian @ladyglaucoma.bsky.social · 03/05/2025
These are my people! 🫶
040
Reposted by Revathi Balasubramanian
Seth Blackshaw @sethblackshaw.bsky.social · 29/04/2025
Our latest manuscript (7 years in the works) tackles the question of how diurnal ground squirrels evolved a cone-dominant retina, in contrast to the ancestral rod-dominant retina retained by virtually all other mammals./1 www.biorxiv.org/content/10.1...
biorxiv.org
Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.
Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the rod-dominant retinas of most mammals. The molecular mechani...
68531
Reposted by Revathi Balasubramanian
Dr. Lucky Tran @luckytran.com · 28/04/2025
Deaths from heart disease down 75%, that’s NIH. Deaths from stroke down 75%, that’s NIH. HIV/AIDS no longer a death sentence, that’s NIH. 99% of FDA approved drugs in the last decade, that’s NIH. Please show this video to anyone who doesn’t understand why the NIH is so important.
5650352379
Revathi Balasubramanian @ladyglaucoma.bsky.social · 27/04/2025
Will be at #ARVO next week and would love to catch up, vision science folk! I am also presenting a talk on May 6th on trascriptomics in aging and glaucoma.
150
Reposted by Revathi Balasubramanian
Bob Johnston @bobbyjeyeguy.bsky.social · 22/04/2025
Wanna grow organoids to understand human retinal development as a research assistant? Wanna help run the lab as a lab manager? The Johnston lab is hiring a research assistant/lab manager. If you are interested, please apply (also please share!): jobs.jhu.edu/job/Baltimor...
jobs.jhu.edu
Research Technologist
Research Technologist
0410
Reposted by Revathi Balasubramanian
Sonali Majumdar @sonali-m-19.bsky.social · 21/04/2025
Scientists must explore R&D careers beyond U.S. in current climate. My @insidehighered.com article today outlines approaches to explore global research careers for U.S. trained early-career scientists, particularly international scientists. 1/2 www.insidehighered.com/opinion/care...
insidehighered.com
Approaches for Finding International Research Jobs (opinion)
For U.S.-trained scientists searching for early-career research opportunities in other countries, Sonali Majumdar suggests some approaches to consider.
44519
Reposted by Revathi Balasubramanian
Science Magazine @science.org · 09/04/2025
Exclusive: Weeks after President Donald Trump’s administration ordered NIH to pull $250 million in biomedical research grants to Columbia University, the agency is freezing all remaining grant money owed to the university until further notice. scim.ag/4if5Rg1
scim.ag
NIH freezes all research grants to Columbia University
Amid negotiations with Trump, the university could risk losing nearly $700 million
82728465
Reposted by Revathi Balasubramanian
Jeremy Berg @jeremymberg.bsky.social · 09/04/2025
See, if you just cooperate with the administration and comply, it all turns out OK... www.science.org/content/arti...
science.org
NIH freezes all research grants to Columbia University
Amid negotiations with Trump, the university could risk losing nearly $700 million
614035
Revathi Balasubramanian @ladyglaucoma.bsky.social · 07/04/2025
Spotted Valerie Wallace in this. Need to bring her here to bluesky. Or maybe we move to Canada? @blockintheback.bsky.social @michelcayouette.bsky.social @flyeyelab.bsky.social
050
Reposted by Revathi Balasubramanian
Seth Blackshaw @sethblackshaw.bsky.social · 05/04/2025
Our latest manuscript on glia-to-neuron conversion in retina is out in @elife.bsky.social. We show that AAV-mediated overexpression of Oct4 induces glia-to-bipolar cell conversion in wildtype retina, and that this is greatly enhanced by loss of function of Rbpj. elifesciences.org/reviewed-pre...
elifesciences.org
Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
44915
Reposted by Revathi Balasubramanian
Paloma Liton @palomaliton.bsky.social · 04/04/2025
📣 Call for @iser.bsky.social Members! Want to take on a leadership role at ISER? We're seeking volunteers for: 🟢 Members • 📣 Comms • 💰 Fundraising • 🌱 Early Career Help shape the future of ISER—get involved! #ISER #Volunteer #Leadership #ScienceCommunity #EarlyCareerResearchers
043
Revathi Balasubramanian @ladyglaucoma.bsky.social · 02/04/2025
Just found out NEI science communications Director was among the ones purged by the recent NIH RIF. I personally benefitted from his work - he highlighted our NEI funded Neuron publication when I was on the job market. Every week I enjoyed his NEI research update. Thank you for everything you did.
0265
Reposted by Revathi Balasubramanian
John Wallingford @jbwallingford.bsky.social · 02/04/2025
Director of the Nat'l Institute of Child Health and Human Development (NICHD) was summarily dismissed yesterday. So here's your reminder that birth defects kill twice as many American kids as cancer. But there is no St. Jude's for birth defects. Only the NICHD. www.nature.com/articles/d41...
nature.com
‘One of the darkest days’: NIH purges agency leadership amid mass layoffs
In shock move, four institute directors at the US biomedical agency are removed from their posts.
5167102
Reposted by Revathi Balasubramanian
Jeremy Berg @jeremymberg.bsky.social · 28/03/2025
Powerful new Washington Post story up... wapo.st/426d9fT (Gift link) 1/n
wapo.st
Trump promised scientific breakthroughs. Researchers say he’s breaking science.
NIH funding for biomedical research has abruptly fallen by billions of dollars, with many grant decisions on hold. Trump officials say they’re reviewing the agency.
6340146
Revathi Balasubramanian @ladyglaucoma.bsky.social · 27/03/2025
My lab studies mechanisms of pediatric glaucoma and the development of tissues affected (Schlemm's canal and trabecular meshwork). I am getting creative with fundraising because, well... So if you know someone who might be interested in funding our work: joinus.cuimc.columbia.edu/index.cfm?fu...
joinus.cuimc.columbia.edu
I'm supporting Your Columbia!
Your Columbia is your opportunity to be a part of the unparalleled research, education, and clinical care that takes place every day at Columbia University Irving Medical Center. It’s a potent and imp...
12913
Reposted by Revathi Balasubramanian
Eric Topol @erictopol.bsky.social · 27/03/2025
On the potential risk of a type of optic neuropathy from GLP-1 drugs. One of several retrospective studies with mixed results jamanetwork.com/journals/jam...
56013
Revathi Balasubramanian @ladyglaucoma.bsky.social · 20/03/2025
@schalleklab.bsky.social : look who I met today and went down the Rochester memory lane!
170
Reposted by Revathi Balasubramanian
Center for Vision Research @upstate-vision.bsky.social · 18/03/2025
congratulations to our very own Dr. Preethi Ganapathy on her NEI R01 award to investigate optic nerve head astrocyte sensitivity to glaucomatous insult. www.upstate.edu/news/article...
upstate.edu
Upstate research could pave the way for improved glaucoma treatments | Upstate News | SUNY Upstate
With a $2.1 million grant, Preethi Ganapathy, MD/PhD, is using 3D models to explore how optic nerve cells respond to pressure, aiming to uncover new ways to prevent vision loss from glaucoma.
715625