Reposted by Revathi Balasubramanian
New preprint! Another piece from @gaparicio.bsky.social thesis, now exploring the role of PALS1 (aka Nok, or MPP5) in lamination and photoreceptor progenitors positioning in the developing zebrafish retina and retinal organoids: tinyurl.com/yya754tf
tinyurl.com
Reduction of PALS1/Nok disrupts retinal lamination through altered cell positioning while preserving photoreceptor self-organization capacity
The vertebrate neural retina is composed of several neuronal types that precisely organize into layers, with photoreceptors facing the outer surface and the projection neurons, retinal ganglion cells,...