Sign in

Mioara Larion, Ph.D

@larionmioara.bsky.social
201 followers 519 following 6 posts

Principal Investigator Lead of Cancer Metabolism Lab at @NCI. Studying lipid metabolism in brain tumors. Views are my own.

PostsRepliesMedia
Reposted by Mioara Larion, Ph.D
The Brain Prize @brainprize.org · 21/10/2025
“I was advised that having multiple children would detract from my scientific career. But I actually think that it has greatly benefited it.” Prof. @michellemonje.bsky.social, Neurology and Neurological Sciences at Stanford University, #BrainPrize2025. #Neuroscience youtu.be/f7sbSuWie5A?...
youtu.be
Balancing a career in science and personal life
YouTube video by BrainPrize
0178
Mioara Larion, Ph.D @larionmioara.bsky.social · 08/09/2025
AI denoising transforms spontaneous Raman - 80 % faster cell acquisition and a realistic path to high-throughput single cell profiling. See our back cover in Advanced Optical Materials. @adrianlita.bsky.social advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com
RADAR: Raman Spectral Analysis Using Deep Learning for Artifact Removal (Advanced Optical Materials 25/2025)
Raman Spectroscopy In article 10.1002/adom.202500736, Ion Petre and co-workers introduce RADAR, two lightweight deep learning models that simultaneously denoise and correct Raman spectra, reducing da...
022
Mioara Larion, Ph.D @larionmioara.bsky.social · 28/07/2025
Excited to be part of this study! We show that we can reduce the noise in spontaneous Raman spectra, thus making the live cell acquisition faster! advanced.onlinelibrary.wiley.com/doi/full/10.... Also the journal picked this as the back cover! @adrianlita.bsky.social
advanced.onlinelibrary.wiley.com
RADAR: Raman Spectral Analysis Using Deep Learning for Artifact Removal
RADAR is introduced, two lightweight deep learning models for artifact removal, capable of simultaneous denoising and correction of Raman spectra, significantly accelerating high-quality data acquisi....
021
Mioara Larion, Ph.D @larionmioara.bsky.social · 01/05/2025
So nice to participate in the annual retreat of Staff Scientist at NCI! Our work was highlighted by Dr. Adrian Lita @adrianlita.bsky.social who gave a fantastic presentation. Here is the link the the publication: pubmed.ncbi.nlm.nih.gov/38828478/
062
Reposted by Mioara Larion, Ph.D
Eugene Valkov @eugenevalkov.bsky.social · 24/04/2025
Will be taking a deep dive into this today. Congrats to Joe Lobel and Nick Ingolia! #RNAsky #RNAbiology www.nature.com/articles/s41...
nature.com
Deciphering disordered regions controlling mRNA decay in high-throughput - Nature
Using high-throughput functional profiling, how disordered regions control mRNA stability and translation is explored.
04013
Reposted by Mioara Larion, Ph.D
Christian Frezza @frezzalab.bsky.social · 11/04/2025
www.nature.com/articles/s42... Metabolites are not genes. repeat, please!
nature.com
Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics - Nature Metabolism
Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites compared with genes, pat...
09131
Reposted by Mioara Larion, Ph.D
UCSF Neurosurgery @neurosurgucsf.bsky.social · 26/03/2025
A big congratulations to @ucsanfrancisco.bsky.social neurosurgeon and scientist Shawn Hervey-Jumper, MD on being honored with the Mitchel S. Berger, MD Endowed Professorship! 🎉 @ucsfhealth.bsky.social @ucsfcancer.bsky.social #UCSFProud
Shawn Hervey-Jumper, MD, sitting in his chair with Heather Hervey-Jumper, MD (his wife), his daughters, and Mitchel Berger, MD, standing around him.Shawn-Hervey Jumper, MD, receives a standing ovation as he takes the stage following remarks from neurosurgery department chair Edward Chang, MD.UCSF Brain Tumor Center director Mitchel Berger, MD, delivering his remarks at the podium.
0135
Reposted by Mioara Larion, Ph.D
OncoDaily @oncodaily.bsky.social · 12/03/2025
Kimryn Rathmell was Awarded 2025 ACS Medal of Honor On March 8, 2025, Dr. Kimryn Rathmell was honored with the American Cancer Society’s Medal of Honor, the highest recognition for those whose contributions have made a transformative impact in the fight against cancer. 🏅
1161
Reposted by Mioara Larion, Ph.D
Ludwig Cancer Research @ludwigcancer.bsky.social · 11/03/2025
Congratulations to Ludwig @unil.bsky.social’s Douglas Hanahan on being honored with the 2025 Pezcoller Foundation-@theaacr.bsky.social International Award for Extraordinary Achievement in Cancer Research for his seminal contributions to the field. Learn more here: bit.ly/3DGCnt6 #CanSky #OncoSky
0135
Reposted by Mioara Larion, Ph.D
Ana Luisa Correia @alpcorreia.bsky.social · 17/11/2024
If you want to work at the interface of #cancer #dormancy #immunity in beautiful #Lisbon reach out to me. We have positions fully funded by #LaCaixa Join our amazing blue sky at Champalimaud Foundation ☀️
1248
Reposted by Mioara Larion, Ph.D
Phillip White @phillipjwhitephd.bsky.social · 15/11/2024
Registration is open for #METPHYS2025! www.sablesys.com/metphys2025-...
03421
Reposted by Mioara Larion, Ph.D
Cosimo Commisso @cosimocommisso.bsky.social · 04/12/2024
I'm thrilled to share our latest research, published in Nature Communications. This work highlights how pancreatic cancer cells hijack cell polarity proteins to regulate macropinocytosis and tumor metabolism, shedding light on potential therapeutic vulnerabilities. www.nature.com/articles/s41...
nature.com
Cell polarity proteins promote macropinocytosis in response to metabolic stress - Nature Communications
Cancer cells rely on macropinocytosis to survive in a nutrient-deprived environment. Here, Lambies et al. identified various members of the cell polarity protein network as essential regulators of mac...
47316
Reposted by Mioara Larion, Ph.D
Eddy Pasquier 🧪🇫🇷🇦🇺 @eddpasquier.bsky.social · 07/12/2024
Wait what?!? Metabolism regulates anti-tumor immunity? I can’t believe it 😉
071
Reposted by Mioara Larion, Ph.D
Blake Wilde @brwilde.bsky.social · 28/02/2025
📢 Postdoc Opening – Metabolism & Cancer! 📢 Looking for a motivated postdoc to explore how metabolism regulates tumor initiation at Roswell Park in Buffalo, NY! Join us to tackle big questions with cool science in a collaborative environment. Interested? DM me! #PostdocJobs #CancerMetabolism
055
Reposted by Mioara Larion, Ph.D
htw @heniek-htw.bsky.social · 10/02/2025
•Single-cell tracking of tumor organoids maps cell-type transitions & #metabolism • #Cancer stem & differentiated cells vary in glycolytic rates & exchange #lactate •Lactate drives cancer stem cell identity by disrupting cell fate commitment •Lactate metabolism epigenetically activates MYC oncogene
https://www.sciencedirect.com/science/article/pii/S1550413125000026
054
Reposted by Mioara Larion, Ph.D
Jean-Ehrland RICCI @jer-06.bsky.social · 12/01/2025
Here I discuss the link between metabolism and immunosurveillance and how to exploit this link to improve treatment. I hope you find it interesting and useful. 🤗 Tumor-induced metabolic immunosuppression: Mechanisms and therapeutic targets: Cell Reports www.cell.com/cell-reports...
cell.com
Tumor-induced metabolic immunosuppression: Mechanisms and therapeutic targets
This review explores how metabolic reprogramming in cancer and immune cells impacts antitumor responses. It highlights how altered metabolism affects immune function and cancer progression, discusses therapeutic strategies targeting these pathways, and examines innovative combinations of immunotherapy, cellular therapies, and metabolic interventions to enhance treatment efficacy.
2185
Reposted by Mioara Larion, Ph.D
Science News @scinews.bsky.social · 09/12/2024
Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity #CancerCell "Cell-intrinsic mannose metabolism is a physiological regulator of CD8+ T cell fate, decoupling proliferation/expansion from differentiation" www.cell.com/cancer-cell/...
0333
Reposted by Mioara Larion, Ph.D
The Brain Prize @brainprize.org · 06/03/2025
Watch Lene Skole, the CEO of the @lundbeckfonden.bsky.social explain why The Brain Prize is awarded, and hear from the 2025 winners: @michellemonje.bsky.social @stanfordneuro.bsky.social, @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital. Watch the full film at brainprize.org
095
Reposted by Mioara Larion, Ph.D
Nature Methods @natmethods.nature.com · 06/03/2025
News & Views from @vadim-demichev.bsky.social: Advances in single-cell proteomics allow quantification of half of the expressed proteome in an individual cell. www.nature.com/articles/s41...
nature.com
Entering the era of deep single-cell proteomics - Nature Methods
Advances in single-cell proteomics allow quantification of half of the expressed proteome in an individual cell.
1187
Reposted by Mioara Larion, Ph.D
Karl Deisseroth @deisseroth.bsky.social · 05/03/2025
Congratulations to these two outstanding physician-neuroscientists! Many people now are familiar with the fascinating fundamental research of @michellemonje.bsky.social but most people probably don't know she is a truly great physician. I'm fortunate to be inspired by her every day, in every way.
310310
Reposted by Mioara Larion, Ph.D
Nature Metabolism @natmetabolism.nature.com · 06/03/2025
RESEARCH | T Walzer, A Marçais et al. (Univ Lyon): Natural killer cells are shown to rely on exogenous pyruvate import to support effector functions 🧫✨ bit.ly/4brHAld
bit.ly
Pivotal role of exogenous pyruvate in human natural killer cell metabolism - Nature Metabolism
Kern Coquillat et al. show that NK cells rely on exogenous pyruvate import to support effector functions.
011
Reposted by Mioara Larion, Ph.D
Winkler Laboratory @winklerlab.bsky.social · 05/03/2025
📢 We are excited and honored to announce that Frank Winkler received #thebrainprize2025, together with @michellemonje.bsky.social, for pioneering the field of #cancerneuroscience. 💐 @brainprize.bsky.social #neuroscience #cancer brainprize.org
brainprize.org
The Brain Prize
The Brain Prize is the world’s largest prize for brain research that is awarded each year by the Lundbeck Foundation.
45211
Reposted by Mioara Larion, Ph.D
Johanna Joyce @johannajoyce.bsky.social · 05/03/2025
Congratulations to the Brain Prize 2025 recipients - Michelle Monje & Frank Winkler 🎉 Recognized for ground-breaking discoveries in cancer neuroscience 🧠🧪 that have transformed oncology It was a privilege to write on their incredible findings - here with their inspiring biographies: brainprize.org
1387
Mioara Larion, Ph.D @larionmioara.bsky.social · 06/03/2025
Congratulations @michellemonje.bsky.social and @winklerlab.bsky.social for this well deserved recognition!
091
Reposted by Mioara Larion, Ph.D
The Brain Prize @brainprize.org · 05/03/2025
Congratulations to winners of The Brain Prize 2025! Professors @michellemonje.bsky.social, @stanfordmedicine.bsky.social and @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital, have pioneered the field of Cancer Neuroscience. Learn more: brainprize.org/winners/canc...
114036