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Joe Lalli

@lalli.bsky.social
28 followers 132 following 15 posts

Recent PhD graduate from Dr. Donna Werling's lab (UW-Madison), current MD student. I make tools to help understand how our genes shape how we think. Applying to psychiatry residencies in the 2025-2026 cycle.

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Reposted by Joe Lalli
Megan Dennis @mydennis.bsky.social · 21/07/2025
Check out our latest work co-led by @dcsoto.bsky.social and @jmuribescr.bsky.social identifying hundreds of human duplicated gene families using the new T2T-CHM13 assembly, with a focus on those potentially contributing to brain evolution 🧪: authors.elsevier.com/a/1lTQtL7PXu...
authors.elsevier.com
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Sharon 🪳🌹 @sharonk.bsky.social · 14/06/2025
the virgin star spangled banner vs the chad battle hymn of the republic
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Rajiv McCoy @rajivmccoy.bsky.social · 23/05/2025
Congrats to Dr. @saracarioscia.bsky.social and Dr. Dylan Taylor!!
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Josh Marshall @joshtpm.bsky.social · 02/04/2025
It's getting a lot of attn today. But even before today most of the country had very little idea of what has happened at NIH or through it the entire ecosystem of biomedical research in the US. Simply put, Musk, Kennedy & Trump exploded a bomb right in the middle of cancer cure research in the US.
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Rajiv McCoy @rajivmccoy.bsky.social · 03/03/2025
In work led by @lalli.bsky.social, we present recombination maps and a diverse haplotype reference panel (1000 Genomes Project) for the T2T-CHM13 human reference genome. These resources improve the accuracy of phasing and imputation, especially around common CNVs. www.biorxiv.org/content/10.1...
biorxiv.org
A T2T-CHM13 recombination map and globally diverse haplotype reference panel improves phasing and imputation
The T2T-CHM13 complete human reference genome contains ~200 Mb of newly resolved sequence, improving read mapping and variant calling compared to GRCh38. However, the benefits of using complete refere...
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Joe Lalli @lalli.bsky.social · 01/03/2025
Just a reminder that the NIH has been shut down, and nobody is reporting it. $29 billion in congressionally allocated research funds have been suspended with no announcement, timeline, or explanation. @joshtpm.bsky.social, why has this been reported as an “arcane administrative loophole”?
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Adam Sharp @adamcsharp.bsky.social · 31/03/2024
Me, a fan of The Killers AND a critic of whitewashing in fiction: “He doesn’t look a thing like Jesus”
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Captain Howdy @captainhowdy.bsky.social · 31/03/2024
Somehow, Jesus returned.
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Dave Weigel @daveweigel.bsky.social · 31/03/2024
Guess who’s back
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Brendel @brendelbored.bsky.social · 19/01/2024
I kind of think the Jordan Peterson types are right that there’s a deep hunger among some young men to explore their masculinity and it’s pretty unfortunate that they’ve been duped into thinking weeping beef Professor and homophobic UFC fighter are better options than “guy in town who is good dad”
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Sansa Sandisk @cheatlines.co · 19/01/2024
the "DEI pilots" thing is not only untrue, but the opposite of true. The piloting profession in the late 20th century was so dominated by one Guy Type that they had to invent a new kind of training that forced pilots to listen to their first officers so they would stop flying planes into the ground
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karanormal activity 💜 @deadontheoutside.bsky.social · 29/12/2023
[delivery room] mom: it's a boy. let's name him after you. dad: no, let him go first, i've already got a name. *all the dads high-five*
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Sergio Tenenbaum @sergioten.bsky.social · 23/12/2023
Word defaults to "Keep source formatting" when you paste, while Powerpoint defaults to "Match destination formatting". EVERYONE KNOWS it should be the exact opposite; this is positively evil.
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Joseph Galbo @josephgalbo.bsky.social · 21/12/2023
Much of my early time in gov
A picture of Agent Mulder from the TV show the x files. The text reads: I bring a sort of silly goose vibe to the situation that serious geese don't really understand.
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Dmitriy @dmitriy.bsky.social · 10/12/2023
🧪An estimated one in 10 people, about nine million Egyptians, were chronically infected with HepC. In a public health campaign extraordinary for both its scale and its success, Egypt screened its entire population, brokered a deal for hugely discounted drugs and cured almost everyone with the virus.
nytimes.com
Egypt Wiped Out Hepatitis C. Now It Is Trying to Help the Rest of Africa.
Effective drugs that have made the disease curable have yet to reach most of the region.
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Doug Mack @douglasmack.bsky.social · 07/12/2023
It's incredible how accurately Shel Silverstein predicted AI decades ago
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Joe Lalli @lalli.bsky.social · 24/11/2023
!foryou
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Graham J. @grahamj.bsky.social · 15/11/2023
An extremely wise friend once called Gamergate the Spanish Civil War of the modern fascist movement
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Amanda Wong @amandawtwong.bsky.social · 09/11/2023
Honestly, I wish some people would just admit to themselves, “Some young people annoy me” and it doesn’t have to turn into a whole… fucking human rights issue
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