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Reposted by José Uribe-Salazar

Osman Sharifi @osmansharifi.bsky.social · 02/06/2025

🧬 Excited to share our new research exploring the critical intersection between genetics and environmental toxins in neurodevelopmental disorders! In our latest paper, we discovered remarkable overlap between PCB exposure effects and MeCP2 mutations. www.biorxiv.org/content/10.1...

biorxiv.org

Female cortical cellular mosaicism underlies shared MeCP2 and PCB impacted gene pathways

Etiologies of neurodevelopmental disorders involve genes and environment however their interactions are understudied. Rett Syndrome (RTT) is an X-linked, dominant neurodevelopmental disorder caused by...

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