iiinova — where your digital self keeps evolving

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Hubrecht Institute @hubrechtinstitute.bsky.social · 15/10/2026

The @sonnenlab.bsky.social discovered a functional role for oscillation frequencies in keeping the gut cells in balance. They experimentally changed the frequency of Hes1 oscillations in intestinal organoids and showed that this altered cell-type composition.https://www.hubrecht.eu/cells-got-rhythm/

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 16/10/2026

In trying to track down Jonathan Hodgkin's Wormbreeders Gazette masterpiece "A modest Proposal" (still not found I did find this related gem by @wyomingwormboy.bsky.social helpimascientist.com/wp-content/u...

Names Given to Children of C. elegans Scientists
Will Now Require Jonathan Hodgkin’s Approval
(Oxford UK). In a move widely viewed as a gross
overreach on the part of the C. elegans Genetics
Center and WormBase, Jonathan Hodgkin has been
authorized to oversee the naming of all human
progeny spawned by C. elegans researchers. The
apparent last-minute power grab follows in the wake
of the announcement that Tim Schedl of Washington
University will soon be taking over for Hodgkin.
AlthoughAlthough initial reports suggested that all children would be categorized by
three- or four-letter names, followed by a number, recent statements from
Hodgkin suggest at least some degree of flexibility. “We’re not trying to
dictate everything,” said a conciliatory Hodgkin, “however, basic standards
must be maintained for the sake of the field.” “For example,” he continued,
“this practice of christening all of one’s offspring with the same first letter,
like ‘Kylee’, ‘Kaleb’ and ‘Kirsten’, simply must stop.” “Also,” added a visibly
frustrated Hodgkin, “enough of the weird spellings for common names
already. There is no bloody ‘y’ in Alex. The pillars of our field all have boring
traditional names like Bob, Barbara, John, Sydney, Judy, and Marty. It didn’t
stop them from distinguishing themselves, did it?” “It’s what’s on the inside
that counts,” went on Hodgkin, forcing a smile and speaking more calmly.
“But if you’re thinking of naming your daughter McKayla or Micalya or some
such nonsense, think again. Maybe that’s okay for a Drosophila geneticist, but
not in my house and not on my watch dammit!”

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Grosshans Lab @labgrosshans.bsky.social · 09/09/2026

Very proud of Jana 👇 for receiving the 2026 Ed Fischer Prize recognizing the best dissertation at FMI in 2025! And her presentation at the award ceremony at the FMI's Annual Meeting would have merited a separate award for most entertaining/dry-humored talk - wonderful! @fmiscience.bsky.social

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FMI science @fmiscience.bsky.social · 27/08/2026

Looking forward to taking part in the Doctoral Insights Symposium on 10 September and sharing an inside perspective on PhD life at FMI. Join us online for an open conversation about doctoral research in Europe! 👇

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SIRD - Swiss Initiative for RNA & Disease @swissinitiativerna.bsky.social · 26/08/2026

Join the 4th Swiss RNA Therapeutics Summit on 28 January 2027 at the University of Bern. Connect with experts from academia, biotech and pharma and explore the latest developments in RNA-based medicines. 📝 Registration opens soon. More information: www.rnatx.ch #RNA #RNATherapeutics

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Reese Richardson @reeserichardson.bsky.social · 25/08/2026

A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵

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Teresa Rayon @trayon.bsky.social · 15/08/2026

Our work on the role of the proteasome in developmental tempo is out!!!! 🐭⌛️👤⏳ Six years after identifying an association between protein stability and developmental tempo, we now demonstrate a causal link between protein turnover and developmental tempo through proteasomal degradation

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Max Heiman @heiman.bsky.social · 16/08/2026

For the last year, aECM Club seminars have brought together researchers working on apical ECM in diverse species and tissues - yeast cell wall, C. elegans cuticle, Drosophila lens, mammalian inner ear and pancreatic lumen, and many others. Sign up for 2026-27: forms.gle/DDJUxGLkcSRb...

forms.gle

aECM Club 2026-27

Dear aECM researchers, Thank you for your interest in aECM Club! Feel free to forward this brief survey to any colleagues and trainees who may be interested.

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David Brückner @davidbrueckner.bsky.social · 10/08/2026

If you're looking for a PhD position, or know someone looking checkout our interdisciplinary PhD Fellowship program! We are always looking for talented students with a physics or computational background to join our group to work on the physics of living systems!

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Grosshans Lab @labgrosshans.bsky.social · 05/08/2026

So how commonly do RBPs act through only few targets? At least In the context of developmental timing, this may not be unusual: LIN41/TRIM71, lin-4 miRISC, and let-7 miRISC each also act through four or fewer targets. Clearly, binding data alone is insufficient to invoke network effects. n/n

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Grosshans Lab @labgrosshans.bsky.social · 05/08/2026

This is a striking parallel to mammalians, including humans, were LIN28 controls the age of onset of puberty. 5/n

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Grosshans Lab @labgrosshans.bsky.social · 05/08/2026

Whereas lin-28 was known to be required for the correct number and identity of larval stages, we also found that it controls developmental tempo: animals lacking lin-28 develop consistently more slowly than the wild type - and also this phenotype depends on regulation of let-7 and lin-46 4/n

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Grosshans Lab @labgrosshans.bsky.social · 05/08/2026

First author Jana Brunner teamed up with colleagues @fmiscience.bsky.social to show that among the many LIN28 binders, let-7 and lin-46 suffice to explain various developmental timing phenotypes (precocious vulva formation, skin differentiation and exit from the molting cycle). 3/n

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Grosshans Lab @labgrosshans.bsky.social · 05/08/2026

Mammalian and worm LIN28 are known to bind hundreds of transcripts. This is also what we observed - yet among those, only lin-46 mRNA and let-7 miRNA were up in animals lacking lin-28. So there either had to be different mechanisms of regulation, or these were the sole critical targets. 2/n

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Grosshans Lab @labgrosshans.bsky.social · 05/08/2026

RNA-binding proteins (RBPs) often bind numerous transcripts - but do they act through a network effect? Our new paper in @plosbiology.org shows that the highly conserved LIN28 RBP controls developmental timing in C. elegans larvae through only two targets. doi.org/10.1371/jour... 1/n

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Grosshans Lab @labgrosshans.bsky.social · 05/08/2026

Tweetorial/thread with some academic details to follow 👇

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FMI science @fmiscience.bsky.social · 03/08/2026

Looking forward to joining the Doctoral Insights Symposium on 10 September and introducing students to the FMI PhD Program, our research, and life in Basel’s vibrant biomedical ecosystem 🧬

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FMI science @fmiscience.bsky.social · 08/07/2026

Much of the genome is made up of repetitive DNA sequences that trace back to ancient mobile elements. Two new studies from the @marcbuhler.bsky.social group, now published in @cp-molcell.bsky.social, show how cells keep these potentially disruptive sequences under control. www.fmi.ch/news-events/...

fmi.ch

How cells keep genomic hitchhikers under control

Much of the genome is made up of repetitive DNA sequences that trace back to ancient mobile elements, many of which have lost their ability to copy themselves into new locations but can still cause pr...

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FMI science @fmiscience.bsky.social · 22/06/2026

Undergraduate or master’s student in the life sciences looking for fully funded PhD programs in Europe? Don’t miss the free @docinsightssymp.bsky.social on Sep 10 at 14:00 CET, featuring 20+ programs across 7 countries, including the FMI International PhD Program. Register: www.doctoralinsights.at

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FMI science @fmiscience.bsky.social · 23/06/2026

We’re delighted to welcome @computingcaitie.bsky.social to the FMI next year! Her work will bring an interdisciplinary perspective spanning structural biology, quantitative imaging and computational analysis to our institute, opening exciting new ways to study ciliary structure and dynamics.

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FMI science @fmiscience.bsky.social · 23/06/2026

Congratulations to FMI senior group leader Jeff Chao and his team for being awarded €2.5 million through the @erc.europa.eu Advanced Grant scheme to study how RNA controls gene expression in living cells, with the goal of uncovering fundamental principles of RNA biology. www.fmi.ch/news-events/...

fmi.ch

Jeff Chao’s group awarded €2.5m ERC grant to study RNA in living cells

FMI senior group leader Jeff Chao and his team have been awarded €2.5 million through the prestigious European Research Council Advanced Grant scheme to study how RNA controls gene expression in livin...

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Mike Dorrity @mwdorr.bsky.social · 19/06/2026

First pre-print from the lab, a collaborative effort led by Jess Bourn @bournsupremacy.bsky.social, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype? www.biorxiv.org/content/10.6...

biorxiv.org

Quantitative mapping of heterochrony to species-specific phenotypes

The genetic program of animal development is conserved, but its rate of execution varies across species. Heterochrony, shifts in the relative timing of developmental events, generates phenotypic varia...

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FMI science @fmiscience.bsky.social · 16/06/2026

We’re excited that the FMI is participating in the Doctoral Insights Symposium for the first time! Registration is now open — don’t miss this opportunity to explore top PhD programs in life sciences.

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Grosshans Lab @labgrosshans.bsky.social · 14/04/2026

Looking forward to seeing you all at the #aECM club today!👇

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meisterlab.bsky.social @meisterlab.bsky.social · 04/03/2026

Exciting news: Our RNA community in @uniregensburg.bsky.social is set to grow! We are opening a Junior Group Leader position in RNA biochemistry / ribonucleases / RNA stability. A great opportunity to start your own team within our collaborative RNA network. Details & application 👇

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Torben Heick Jensen @heick.bsky.social · 06/03/2026

Postdoc positions available in my lab in Aarhus, Denmark on 'Mammalian Nuclear RNA Production and Turnover Systems'. Please get in touch for further information or simply apply here: mbg.au.dk/en/news-and-...

mbg.au.dk

Postdoc positions in Nuclear RNA Biology - Vacancy at Aarhus University

Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University

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Grosshans Lab @labgrosshans.bsky.social · 19/02/2026

Join us 👇. Together with our CompBio and Proteomics platforms, we'd love to work with you on examining protein dynamics!

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FMI science @fmiscience.bsky.social · 12/02/2026

🚀 We’re hiring! The Structural Biology Platform is seeking a Project Leader to advance cryo-electron tomography and expand capabilities at the FMI. Join a vibrant research community at the interface of structural biology, cell biology & disease mechanisms. Apply at: www.fmi.ch/education-ca...

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FMI science @fmiscience.bsky.social · 06/02/2026

👩‍🔬 On February 11, to mark the International Day of Women and Girls in Science, we’re hosting a panel discussion on how scientific progress and gender equality can advance together. The panel brings together voices from academia, industry, and EDI. Join us for this important conversation! #IDWGS

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Johannes Felsenberg @felsenberg.bsky.social · 05/02/2026

Very thankful for this thoughtful dispatch by @shaisrael.bsky.social sky.social and Moshe Parnas about our work. Learning and memory: Forgetting to remember: Current Biology www.cell.com/current-biol...

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FMI science @fmiscience.bsky.social · 19/01/2026

Our annual brochure “Year in Review” is out now! It highlights the FMI’s key scientific publications, major events, and facts & figures from 2025, a year that marked our 55th anniversary. www.fmi.ch/news-events/...

fmi.ch

FMI Year in Review 2025

Our annual brochure highlighting the FMI’s key scientific publications, major events, and facts & figures from the past year is now available. Discover the highlights of 2025, a year that marked the F...

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Biozentrum, University of Basel @biozentrum.unibas.ch · 15/01/2026

Prof. Fiona Doetsch has been awarded the 2026 Louis-Jeantet Prize for Medicine! Her discoveries reveal how neural stem cells support lifelong brain plasticity and repair. 🧠 Read more: www.biozentrum.unibas.ch/news/detail/...

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Grosshans Lab @labgrosshans.bsky.social · 15/01/2026

RNA-binding proteins function through network effects, coordinately binding and weakly regulating many transcripts – or don’t they? Read our new preprint on how LIN28 controls developmental timing through only two targets, one mRNA, one miRNA. doi.org/10.64898/202...

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Grosshans Lab @labgrosshans.bsky.social · 08/12/2025

Please repost - position of Head of Student & Postdoc Affairs available at our Institute in the heart of Europe (Basel, Switzerland) 👇

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Oded Rechavi @odedrechavi.bsky.social · 25/11/2025

Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...

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Ursula von der Leyen @vonderleyen.ec.europa.eu · 10/11/2025

Switzerland is joining Horizon Europe! We are uniting two research powerhouses. For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more. Today is a good day for science, and for our EU-Switzerland partnership.

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Christa Buecker @chribue.bsky.social · 06/11/2025

And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!

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FMI science @fmiscience.bsky.social · 04/11/2025

Now in @embojournal.org: Researchers in @labgrosshans.bsky.social & UCSC found that similar molecular machineries control daily circadian rhythms & developmental timing—showing that evolution can repurpose core timing systems to coordinate both daily cycles & growth. www.fmi.ch/news-events/...

fmi.ch

One clock, two functions: from daily rhythms to development

Scientists at the FMI and the University of California-Santa Cruz have found that similar molecular machineries control daily circadian rhythms and developmental timing. Their work in worms shows that...

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Max Planck Institute of Immunobiology and Epigenetics @mpi-ie.bsky.social · 30/10/2025

Here is the schedule for the next TriRhena Gene Regulation Club at the FMI @fmiscience.bsky.social in Basel 🇨🇭 next week (5 Nov 2025; 14:00-18:45). Exciting topics ahead & we are looking forward to the #newPI talks by @julianeg.bsky.social (MPI) & Anupama Hemalatha (FMI). www.ie-freiburg.mpg.de/grc

Programme of the upcoming TriRhena Gene Regulation Club in Basel on November 5, 2025

https://www.ie-freiburg.mpg.de/gene-regulation-club

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Grosshans Lab @labgrosshans.bsky.social · 29/10/2025

"[In C. elegans] researchers uncovered key principles of cell death and RNA interference [that] paved the way for new therapies and technologies. These breakthroughs were made not because they were sought by design, but because a few scientists, supported by public grants, followed their curiosity"

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SIRD - Swiss Initiative for RNA & Disease @swissinitiativerna.bsky.social · 24/10/2025

🔬 Next in the NCCR RNA & Disease Seminar Series: Prof. Olivia Rissland (Univ. of Colorado School of Medicine, USA)! 📅 27.10. 16:30 – University of Bern, DCBP 📅 28.10. 15:00 – ETH Zurich, Hönggerberg 👉 More info: nccr-rna-and-disease.ch/education/nc... @unibe.ch @ethz.ch @snf-fns.ch

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Wyoming Wormboy @wyomingwormboy.bsky.social · 22/10/2025

For what it’s worth, The Wyoming Worm lab has funding for 5 years along with exciting projects with solid foundations. We are is still looking for capable, dedicated, and fun-to-work-with lab members at all career stages. davidfay@uwyo.edu scholar.google.com/citations?us...

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Grosshans Lab @labgrosshans.bsky.social · 20/10/2025

This invites speculations about the evolution of circadian vs. developmental clocks and the features that make the PER/LIN-42:CK1/KIN-20 module so central to different timing mechanisms – as discussed in the accompanying News & Views article @embojournal.org doi.org/10.1038/s443... . 8/n

doi.org

Old cogs, new clocks: a conserved protein complex controls developmental and circadian timing | The EMBO Journal

EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

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