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Kjetill S Jakobsen

@kjetillsj.bsky.social
106 followers 96 following 19 posts

Evolutionary biologist studying functional, comparative and populations diversity processes

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Reposted by Kjetill S Jakobsen
Genome Biology and Evolution @genomebiolevol.bsky.social · 13/07/2026
Solbakken et al. compared lanternfish genomes, finding great flexibility in their immune systems, challenging perceptions of vertebrate immunity. 🔗 doi.org/10.1093/gbe/... #societyjournal #genome #evolution
doi.org
Loss of Major Histocompatibility Complex I and II Function in the Genome of Glacier Lanternfish Provides Insight Into Evolution of Vertebrate Immune Systems
Abstract. Lanternfishes (Myctophidae) are one of the most abundant and species diverse orders inhabiting the mesopelagic zone. Exploitation of marine resou
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Kjetill S Jakobsen @kjetillsj.bsky.social · 25/06/2026
Loss of MHC I and II function in the genome of glacier lanternfish provides insight into evolution of vertebrate immune systems academic.oup.com/gbe/article/...
academic.oup.com
Loss of MHC I and II function in the genome of glacier lanternfish provides insight into evolution of vertebrate immune systems
Abstract. Lanternfishes (Myctophidae) are one of the most abundant and species diverse orders inhabiting the mesopelagic zone. Exploitation of marine resou
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Reposted by Kjetill S Jakobsen
Molecular Biology and Evolution @molbioevol.bsky.social · 20/05/2026
@robinaraya.bsky.social @mariusmaur.bsky.social @kjetillsj.bsky.social et al. investigated the evolution of bivalent inhibitor cystine knot toxins in spider venom, finding evidence of multiple domain loss events in this family. 🔗 doi.org/10.1093/molbev/msag076 #evobio #molbio
doi.org
Ancient origin and dynamic evolution of bivalent spider toxins
Abstract. Bivalent peptide toxins comprising 2 cysteine-rich domains have evolved from single-domain precursors on multiple occasions in animal venoms, res
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Kjetill S Jakobsen @kjetillsj.bsky.social · 21/05/2026
Ancient origin and dynamic evolution of bivalent spider toxins academic.oup.com/mbe/article/...
academic.oup.com
Ancient origin and dynamic evolution of bivalent spider toxins
Abstract. Bivalent peptide toxins comprising 2 cysteine-rich domains have evolved from single-domain precursors on multiple occasions in animal venoms, res
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Kjetill S Jakobsen @kjetillsj.bsky.social · 18/05/2026
Parasitism loss and the underlying genomics in lampreys - Check out the new preprint😀https://www.biorxiv.org/content/10.64898/2026.05.11.724254v1
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Lee Hsiang Liow (廖珕庠) @lhliow.bsky.social · 10/03/2026
The wonderful @baalsrud.bsky.social led work on a new #bryozoan genome (Flustra foliacea) adding to their macrosynteny story with @oletoerresen.bsky.social @kjetillsj.bsky.social & others @biovitenskap.bsky.social academic.oup.com/jhered/advan... @biovitenskap.bsky.social
academic.oup.com
Chromosomal Fusions Shaped the Genome of the Greater Hornwrack Bryozoan (Flustra Foliacea) (Linnaeus, 1758)
Abstract. The phylum Bryozoa is an understudied, yet commonly-occurring, globally distributed bilaterian metazoan organismal group. They have a colonial li
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Kjetill S Jakobsen @kjetillsj.bsky.social · 06/12/2025
Due to complex evolutionary histories, hybridisations and polyploidizations - just to name some - pan genomes are crucial to plant research. American Journal of Botany bsapubs.onlinelibrary.wiley.com/doi/10.1002/...
bsapubs.onlinelibrary.wiley.com
Pangenomes as a framework for adaptive radiation, speciation, and adaptation
Understanding the genomic basis of diversification is a central goal in evolutionary biology. In recent years, the development and use of pangenomes, a genomic representation of multiple individuals ...
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Earth BioGenome Project 🌍 @ebpgenome.bsky.social · 27/11/2025
Huge congratulations to everyone who made this milestone possible! 🎉🦋 Field teams out exploring 🥾🌿 and lab teams powering the sequencing 🧬 — every single contribution mattered. 🙌✨
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Journal of Experimental Botany @jxbotany.bsky.social · 22/11/2025
🧬 SPECIAL ISSUE REVIEW 🧬 Kearly & Nelson discuss historical and modern approaches and their limitations for identifying and characterizing plant short open reading frame-encoded peptides, and how improved techniques are rapidly changing the field 🌱 🔗 doi.org/10.1093/jxb/... #PlantScience 🧪
Fig. 1.Overview of gene annotation. Genomes contain several different kinds of coding and non-coding genes, some of which encode functional proteins while others yield functional RNAs. Historically, experimental and computational efforts to annotate genes have frequently overlooked the protein-coding potential of genes with short open reading frames (sORFs), leading to their misclassification as non-coding despite producing a functional sORF-encoded peptide (SEP). Functional genomic, genetic, and biochemical data now support the inclusion of this additional class of SEP genes.
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GIFS GALORE @gifs-bot.bsky.social · 19/11/2025
NATURE/NORWAY1.GIF
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Genome Biology and Evolution @genomebiolevol.bsky.social · 20/11/2025
Pegan & Winger tested whether inversions are common within populations without phenotypic polymorphisms in 28 N. American bird species, finding that many polymorphisms are present at balanced frequencies, but possibly segregating neutrally. 🔗 doi.org/10.1093/gbe/evaf205 #genome #evolution #birds
GBE | Large Inversion Polymorphisms are Widespread in North American Songbirds

The Yellow-bellied Flycatcher (Empidonax flaviventris) is a North American migratory bird species whose nondescript exterior conceals dramatic genomic polymorphisms, including the putative inversion highlighted on the upper left in elevated orange points. Population genomic data from across the species’ breeding range revealed that this large 57-Mb region produces PCA plots with a distinctive 3-cluster pattern (upper right), not present in other parts of the chromosome (lower left). The middle cluster in the 3-cluster PCA corresponds to individuals heterozygous for the polymorphism, while the other two clusters represent the two classes of homozygotes. Pegan & Winger (2025) used whole genome data to find that evidence for large inversion polymorphisms is common even in species that lack known external phenotypic variation, which is frequently associated with inversions in studies on avian genomics. The depicted polymorphism is one of 170 identified across 28 species. Photo: Georg Langebrake.
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Judith Mank @judithmank.bsky.social · 20/11/2025
Team fish - we need your help! We are trying to build a database of all the fish chromosome-scale genomes where sex chromosomes have been identified. Have you build one or some? Do you know someone who has? Can you post the link in the comments? Please spread the word and repost! Thank you!
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Genome Biology and Evolution @genomebiolevol.bsky.social · 18/11/2025
@katharinasures.bsky.social @probstlab.bsky.social et al. analysed CRISPR-Cas systems of metagenome-assembled genomes from two subsurface environments, shedding new light on the diversity of CRISPR spacers in natural microbial communities. 🔗 doi.org/10.1093/gbe/evaf201 #genome #evolution #CRISPR
doi.org
Acquisition of Spacers from Foreign Prokaryotic Genomes by CRISPR-Cas Systems in Natural Environments
Abstract. Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems of bacteria and archaea provide immunities
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Nature Reviews Genetics @natrevgenet.nature.com · 18/11/2025
New online! Harnessing artificial intelligence to advance CRISPR-based genome editing technologies
nature.com
Harnessing artificial intelligence to advance CRISPR-based genome editing technologies
Nature Reviews Genetics, Published online: 18 November 2025; doi:10.1038/s41576-025-00907-1CRISPR-based genome editing has revolutionized biotechnology, enabling precise DNA modifications for research and therapy. The authors review how artificial intelligence, including deep learning, is advancing genome editing by improving guide RNA design, editor protein engineering, novel effector discovery and predicting editing outcomes.
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Francesca Tinti @francescatinti.bsky.social · 18/11/2025
The serpent head of the Oseberg Viking ship, carved in 820, and shown for the first time to the public in the Oslo Historical Museum
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Earth BioGenome Project 🌍 @ebpgenome.bsky.social · 18/11/2025
🌍✨ Why genome sequence mega-diverse countries? A handful of countries hold >70% of Earth’s terrestrial biodiversity — packed with species found nowhere else. These places are evolution’s playground… and extinction’s front line. #Biodiversity 🌿 #GenomeSequencing 🧬 #Genomics 🔬 #ConservationGenomics 🌍
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Science Magazine @science.org · 13/11/2025
An early Triassic bone bed excavated at 78°N changes the story about how marine life recovered after the most cataclysmic extinction in Earth history ~252 million years ago. Learn more in this week's issue of Science: scim.ag/48bLsGI
An early Triassic bone bed excavated at 78°N changes the story about how marine life recovered after the most cataclysmic extinction in Earth history ~252 million years ago. The quantity and diversity of marine reptile and amphibian fossils show that these groups had already radiated into complex oceanic ecosystems by ~249 million years ago.
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Royal Society Publishing @royalsocietypublishing.org · 11/11/2025
The number of low-quality or fraudulent publications is rising to hundreds of thousands per year. It is time to reevaluate current publishing models and outline a global plan. Read the 'Reformation of science publishing: the Stockholm Declaration': royalsocietypublishing.org/doi/10.1098/... #RSOS 🧪
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Genome Biology and Evolution @genomebiolevol.bsky.social · 11/11/2025
The recent GBE paper on whole-genome duplication in Potamopyrgus antipodarum is the focus of November's Highlight. Highlight: Genome Duplication in a New Zealand Snail Holds Clues for the Persistence of (A)sexual Reproduction 🔗 doi.org/10.1093/gbe/evaf198 #genome #evolution #WGD
GBE | Highlight: Genome Duplication in a New Zealand Snail Holds Clues for the Persistence of (A)sexual Reproduction
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Department of Biosciences, University of Oslo @biovitenskap.bsky.social · 07/11/2025
New publication: "A quality standard for conservation of wild #reindeer" with Atle Mysterud from @unioslo-cees.bsky.social & @biovitenskap.bsky.social Published in The Wildlife Society @thewildlifesociety.bsky.social
wildlife.onlinelibrary.wiley.com
TWS Journals
Reindeer is an iconic species in the Arctic and subarctic but populations are declining. An environmental quality standard for reindeer populations assess their overall status (poor, medium, and good...
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Kjetill S Jakobsen @kjetillsj.bsky.social · 07/11/2025
The most original wild reindeer in Norway has been sequenced: Chromosome-level genome assembly of alpine reindeer (Rangifer tarandus tarandus) url: academic.oup.com/jhered/artic...
academic.oup.com
Validate User
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Reposted by Kjetill S Jakobsen
Lee Hsiang Liow (廖珕庠) @lhliow.bsky.social · 03/11/2025
#marineinvert folks, not many #bryozoa genomes, here’s a new one, a Norwegian Flustra foliacea www.biorxiv.org/content/10.1... Genome is "large" (at c. 900Mb). Lead by Helle Baalsrud (NMBU) and Ole Tørresen (UiO). @ebpgenome.bsky.social Norway @kjetillsj.bsky.social
biorxiv.org
Chromosomal fusions shaped the genome of the greater hornwrack bryozoan (Flustra foliacea) (Linnaeus, 1758)
The phylum Bryozoa is an understudied, yet commonly-occurring, globally distributed bilaterian metazoan organismal group. They have a colonial lifestyle and an evolutionary history that spans at least...
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Reposted by Kjetill S Jakobsen
Fabien Burki @fburki.bsky.social · 30/10/2025
Phylogenomic analysis of deep-branching telonemid #protistsonsky academic.oup.com/gbe/advance-...
academic.oup.com
Phylogenomic analysis of deep-branching telonemid
Abstract. The evolutionary history of eukaryotic supergroups has been investigated primarily by large-scale phylogenomics, but one major hindrance to conti
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Department of Biosciences, University of Oslo @biovitenskap.bsky.social · 30/10/2025
New publication highlight the interplay between sound exposure, environmental conditions, and the impact on #zooplankton in areas of #seismic activity. With Josefin Titelman from @biovitenskap.bsky.social Published in @nature.com
nature.com
Zooplankton mortality and distribution around a seismic survey - Scientific Reports
Scientific Reports - Zooplankton mortality and distribution around a seismic survey
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Reposted by Kjetill S Jakobsen
Blanca Jimeno @bjimeno.bsky.social · 23/10/2025
Very excited about this work now out in @molecology! We test whether🐦with ⬆️dispersal propensity differ in the nº CpGs across the genome, with the hypothesis that⬆️CpGs allow for⬆️epigenetically-driven plasticity facilitating environmental coping onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Epigenetic Potential and Dispersal Propensity in a Free‐Living Songbird: A Spatial and Temporal Approach
Natal dispersal is a key life history trait determining fitness and driving population dynamics, genetic structure, and species distributions. Despite existing evidence that not all phenotypes are eq...
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Department of Biosciences, University of Oslo @biovitenskap.bsky.social · 20/10/2025
New publication: "Role of forest edges and other seminatural linear landscape features in structuring wild bee habitat connectivity in intensively managed landscapes" with Marianne Torvanger & Bastiaan Star @biovitenskap.bsky.social Published in Conservation Biology @scbeurope.bsky.social
conbio.onlinelibrary.wiley.com
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Genome Biology and Evolution @genomebiolevol.bsky.social · 20/10/2025
@notothentoma.bsky.social @arcolon14.bsky.social & @jpostlethwait.bsky.social show how Antarctic white-blooded icefishes, the only vertebrates without hemoglobin, independently lost hemoglobin cluster genes, driven by TEs and repeats. 🔗 doi.org/10.1093/gbe/evaf184 #genome #evolution #TEsky
GBE | Hemoglobin-Gene Cluster Deletions in Antarctic White-Blooded Icefishes Facilitated by Transposable Elements

Analyzing numerous genome assemblies of notothenioid fishes, Desvignes et al. demonstrated that in Antarctic white-blooded icefishes, the only vertebrates living without hemoglobin, the two hemoglobin gene clusters were lost independently from one another by different genomic mechanisms, although both mechanisms incriminate transposable and repeat-like elements.
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Sissel Jentoft @jentoft.bsky.social · 15/10/2025
New paper out where we demonstrate how pop gen parameters and scoring of structural variants (inversions) could be affected by the choice of reference genome (both in terms of both quality and relatedness). @unioslo-cees.bsky.social @biovitenskap.bsky.social link.springer.com/article/10.1...
link.springer.com
Reference genome bias in light of species-specific chromosomal reorganization and translocations - Genome Biology
Background Whole-genome sequencing efforts, have during the past decade, unveiled the central role of genomic rearrangements—such as chromosomal inversions—in evolutionary processes, including local a...
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Kjetill S Jakobsen @kjetillsj.bsky.social · 15/10/2025
Article alert: Maurstad, Hoff; Cerca et al. Reference genome bias in light of species-specific chromosomal reorganization and translocations. Now out in Genome Biol. Congrats to Sissel and the team😀 doi.org/10.1186/s130...
doi.org
Reference genome bias in light of species-specific chromosomal reorganization and translocations - Genome Biology
Background Whole-genome sequencing efforts, have during the past decade, unveiled the central role of genomic rearrangements—such as chromosomal inversions—in evolutionary processes, including local a...
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Earth BioGenome Project 🌍 @ebpgenome.bsky.social · 14/10/2025
🧬 Not all DNA comes out easily! Some species lock their secrets behind tough shells, rigid walls, or tricky chemistry. Extracting high-quality DNA can mean cracking exoskeletons, dissolving cell walls, or working around inhibitory compounds — science meets detective work 🔬💥
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CEES, University of Oslo @unioslo-cees.bsky.social · 10/10/2025
forskning.no
Utviklingen av fingrene våre har et svært overraskende opphav
Genregulering som lot oss utvikle fingre, ble først brukt å danne rumpehull hos fisk.
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Sam Bogan @snbogan.bsky.social · 09/10/2025
Excited to share this work, out today in MBE! In polar fishes, we found that antifreeze protein genes expanded in copy number at low temperatures and contracted in the deep sea, highlighting a role of depth and pressure in AFP evolution. 🔗 academic.oup.com/mbe/article/...
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CEES, University of Oslo @unioslo-cees.bsky.social · 10/10/2025
Congratulations, Inga! @biovitenskap.bsky.social
mn.uio.no
Inga is a new member at the Academy - Department of Biosciences
Inga Angelica Frøland Steindal has been accepted as a new member of The Young Academy of Norway. Inga is a researcher at the Center for Ecological and Evolutionary Synthesis (CEES) at the Department o...
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Kjetill S Jakobsen @kjetillsj.bsky.social · 23/09/2025
Article alert! Single Nucleotide Polymorphisms, Structural Variants, and Short Tandem Repeats Capture Distinct Signals of Adaptive Divergence in the Atlantic Puffin url: academic.oup.com/gbe/article/...
academic.oup.com
Single Nucleotide Polymorphisms, Structural Variants, and Short Tandem Repeats Capture Distinct Signals of Adaptive Divergence in the Atlantic Puffin
Abstract. The Arctic has been the scene for (re)colonization, diversification, and adaptation of boreal and Arctic fauna. As anthropogenic warming of the A
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José Cerca @naturalselection.bsky.social · 17/09/2025
🧨 The Naturhistoriska riksmuseet has a position open for a Tenure-Track group Leader position (DDLS fellow). 17 M SEK start-up (1.6 million euros, which will account for your salary / 2 PhDs / 2 Postdocs / plenty of money for starting projects and sending peoeple to conferences). lnkd.in/d5jNr_Ti
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Chris Lennard @cklennard.bsky.social · 11/09/2025
Cool intro to the Earth Biogenome Project (link in the article) … and who doesn’t love our cute Aussie spiders? 🕷️ share.google/XvZI57IbEdNU...
share.google
'Dark DNA' may explain dancing spiders' extraordinary diversity
There are many more species of peacock spider than other animals, scientists think they may know why.
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Genome Biology and Evolution @genomebiolevol.bsky.social · 18/09/2025
The recent GBE Review on approaches to phylogenetic genotype to phenotype mapping is the focus of a new Highlight. Highlight: Leveraging Phylogenomics to Uncover the Loci of Repeated Evolution 🔗 doi.org/10.1093/gbe/evaf164 #genome #evolution #phylogenetics
GBE | Highlight: Leveraging Phylogenomics to Uncover the Loci of Repeated Evolution
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Genome Biology and Evolution @genomebiolevol.bsky.social · 16/09/2025
In a new Review article in GBE, @scientific-arlie.bsky.social et al delve into the growing field of phylogenetic genotype to phenotype mapping (PhyloG2P), discussing advances and future directions for using phylogenomic data to map traits to genomes 🔗 doi.org/10.1093/gbe/evaf150 #genome #evolution
GBE | From Trees to Traits: A Review of Advances in PhyloG2P Methods and Future Directions
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PLOS Biology @plosbiology.org · 15/09/2025
Neuron-specific splicing of Agrin by Nova is essential for AChR clustering at the NMJ. @rnadoctor.bsky.social @lionlchristiaen.bsky.social &co show that this pathway is conserved in tunicates & that the transcription factor Ebf is a key activator of Nova expression @plosbiology.org 🧪 plos.io/3VhTwig
Top left: Two-color double ISH of Nova (green) and Islet (magenta) showing co-expression in the bilaterally symmetric Motor Neuron 2 (MN2) pair of cells (arrows). Note that Nova mRNA distribution appears more nuclear than Islet in these cells at this stage. Top right:  Summary model diagram of a conserved Nova-Agrin-Lrp4 pathway for AChR clustering in Ciona. Upper panel: Summary of conserved pathway, and previously unidentified Ebf-Nova regulatory connection identified in Ciona. Lower panel: Model of proposed mechanism for Ciona Nova-dependent alternative Agrin splicing via binding of KH1 and KH2 domains to two YCAY-rich NISEs identified in the intron 3′ to the Z exons (though not known in what exact orientation or configuration). Inhibitory effect of KH3 domain is relieved by the N- and C-termini. Diagram not drawn to scale. Bottom: Neural-specific CRISPR-mediated disruption of Agrin using sgRNAs results in loss of Acetylcholine receptor A1::GFP clusters (AChRA1::GFP, green) in tail muscles, driven by the Tbx6-r.b promoter. Motor neuron axons labeled by VAChT > Unc-76::mCherry in magenta.
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Nature Reviews Genetics @natrevgenet.nature.com · 27/01/2025
Nuclear mRNA decay: regulatory networks that control gene expression go.nature.com/3WzQ7wc #Review by Xavier Rambout & Lynne E. Maquat
nature.com
Nuclear mRNA decay: regulatory networks that control gene expression - Nature Reviews Genetics
In this Review, the authors summarize our current understanding of nuclear pre-mRNA and mRNA decay pathways. They describe how aberrantly processed mRNAs are targeted for decay in the nucleus and how ...
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Matt Friedman @friedmanlab.bsky.social · 12/09/2025
Do you like cichlids? Fossils? Fossil cichlids? Would you like to study them as part of a graduate degree at the University of Michigan, joining an NSF-funded project? Get in touch.
Multicolored CT model of a fossil cichlid skeleton. Image credit: Austin Babut (project technician).
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Lukas VF Novak @animalculum.bsky.social · 13/09/2025
#Arctic #algae aren't immobile or entombed. They're not just surviving either—they're gliding into record books phys.org/news/2025-09... Ice gliding #diatoms establish record-low temperature limits for motility in a eukaryotic cell www.pnas.org/doi/10.1073/... #protists #microbes #extremophiles
schematic pictures and microscopic photos showing various aspects of movement in single-celled algae
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Catherine Chambers @coastalcultureice.bsky.social · 10/09/2025
📣 New paper out! Ecosystem approach to capelin fisheries #marsocsci link.springer.com/article/10.1...
link.springer.com
Small fish, big implications: considerations for an ecosystem approach to capelin fisheries management - Reviews in Fish Biology and Fisheries
Climate-driven changes in the Subarctic will directly impact capelin populations and the ecosystem they inhabit, including their predators, prey, and physical habitats. Consequently, incorporating eco...
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Kristen Behrens, PhD @behrenskristen.bsky.social · 12/09/2025
So proud to see my cohort-mate’s paper up!
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Camille Roux @crouxevo.bsky.social · 12/09/2025
Hybridization and introgression are major evolutionary processes. Since the 1940s, the prevailing view has been that they shape plants far more than animals. In our new study (www.science.org/doi/10.1126/... ), we find the opposite: animals exchange genes more, and for longer, than plants
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Richard Lenski @relenski.bsky.social · 11/09/2025
Curious to hear thoughts from #popgen, #humangenetics, #genomics folks on recent paper: www.pnas.org/doi/10.1073/... "Directed mutation" in specific human pop'ns seems unlikely to me. DM didn't stand up as proposed in bacteria, but there are hot spots shaped by past selection. Plausible here?
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 12/09/2025
Parallel but distinct adaptive routes in the budding and fission yeasts after 10,000 generations of experimental evolution www.biorxiv.org/content/10.1101/202…
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Christian Landry @christianlandry.bsky.social · 10/09/2025
Really excited to share our latest paper led by @simonaube.bsky.social. Fascinating results examining whether regulatory mutations can lead to adaptation as fast as coding mutations do. #mevosky #evobio #evoSky www.biorxiv.org/content/10.1...
biorxiv.org
Adaptation is less accessible through mutations in promoters than in coding sequences when large effect sizes are needed
Mutations within promoters and coding sequences are both involved in adaptation, but their relative contributions remain to be compared directly. Using the fungal enzyme cytosine deaminase, we examine...
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José Cerca @naturalselection.bsky.social · 10/09/2025
Cool preprint! 🚨 Lanternfish lack MHC I and functional MHC II — yet still produce antibodies! 🧬🐟 www.biorxiv.org/content/10.1...
biorxiv.org
The genome of the Glacier lanternfish shows loss of MHC I and II function and provides insight into evolution of lanternfish immune systems
Lanternfishes (Myctophidae) are one of the most abundant and species diverse orders inhabiting the mesopelagic zone. Exploitation of marine resources has recently attracted increased interest. It is t...
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Rose 🌹 @rose.bsky.team · 09/09/2025
People are talking about Bluesky! From data analyzed between Jan 1 — Aug 18, 2025, we captured 85.5% of share of voice across social, digital, and traditional media, according to Meltwater. This is what death looks like 💀
Screenshot of Meltwater report showing Bluesky is 85.5% of mentions across platforms while other social platforms are much lowerScreenshot of Meltwater report showing Bluesky mentions by search is 10x higher than the alt platform, Threads
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