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The Probst Lab

@probstlab.bsky.social
312 followers 51 following 39 posts

Group for Microbial Systems Ecology, led by @alexjprobst.bsky.social Microbial, viral, & geochemical interactions by linking meta'omics & microscopy Managed by @geomicrosoares.bsky.social

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The Probst Lab @probstlab.bsky.social · 25/08/2026
Not too long left to apply to this great position here in Essen with us! Come work on ERC project Archean Park and uncover carbodioxyphilic metabolisms around the world! 🌋🧬🥼💻
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André Soares @geomicrosoares.bsky.social · 07/08/2026
Come work with us, we're really cool people to hang out with 😁 You'll get to do interdisciplinary research exploring microbial metabolisms during the Archean Eon by investigating the deep biosphere in high-CO₂ ecosystems hundreds of meters below ground. Please retweet and spread the word! 🧬 💻
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The Probst Lab @probstlab.bsky.social · 07/08/2026
We're looking for a Postdoctoral Researcher (f/m/d) for the ERC Synergy project “Archean Park”! 📍 Location: Essen, Germany ⏱ Duration: 36 months (Full-time | EG 13 TV-L) 📅 Start Date: As soon as possible ⏰ Application Deadline: September 2, 2026 www.uni-due.de/karriere/ste...
uni-due.de
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The Probst Lab @probstlab.bsky.social · 02/04/2026
🤯 Manual MAG refinement? Still doing it by hand?? We’ve been there... You could just leave those messy, ill-assigned contigs/scaffolds in your data for NCBI to pick up during your submission… …OR you could add itBins, our new automated MAG refiner by @jmk-ude.bsky.social, to your pipeline!! 🔥
Figure 1 shows the conceptual workflow of the algorithm. It first loads the configuration file and the input data of one or multiple binned metagenomes, yet evaluates each bin individually. It then iteratively processes each candidate bin in the input, going through the refinement tasks, potentially multiple times. The refinement either stops when the last step or a preset stop task have been reached or an unrecoverable error has been encountered. The algorithm tasks can be configured individually.
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The Probst Lab @probstlab.bsky.social · 05/03/2026
We’re out and about yet again, this time in the vulcanic Eifel region drilling with Jens Kallmeyer @gfz.bsky.social 🌋
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The Probst Lab @probstlab.bsky.social · 04/12/2025
Near-zero temperatures, but field sampling is still a-go for the Probst lab 😎 @geomicrosoares.bsky.social @feriel.bsky.social @pengyaoz.bsky.social are out in Regensburg! @unidue.bsky.social @uniregensburg.bsky.social
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The Probst Lab @probstlab.bsky.social · 17/11/2025
We are excited to share @probstlab.bsky.social's latest publication on the diversity of CRISPR-Cas spacers, led by @katharinasures.bsky.social !! 🧬 Have a read!! ➡️ doi.org/10.1093/gbe/... @emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
doi.org
Acquisition of Spacers from Foreign Prokaryotic Genomes by CRISPR-Cas Systems in Natural Environments
Abstract. Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems of bacteria and archaea provide immunities
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The Probst Lab @probstlab.bsky.social · 30/09/2025
Our own @alexjprobst.bsky.social @geomicrosoares.bsky.social and Cristina Moraru have recently authored a @natmicrobiol.nature.com Consensus Statement where they discuss new mechanisms for sequencing data reuse! 🧬💻 Check out their manuscript here: www.nature.com/articles/s41...
nature.com
A roadmap for equitable reuse of public microbiome data - Nature Microbiology
In this Consensus Statement, a consortium of microbiome scientists discuss current sequencing data sharing policies and propose the use of a Data Reuse Information (DRI) tag to promote equitable and collaborative data sharing.
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The Probst Lab @probstlab.bsky.social · 07/08/2025
Fresh out of the oven! 🍞 We're happy to see this preprint out, fruit of a recent collaboration with @wei-biogeochem.bsky.social! 🧬💻 Small 🧵 below going through the main points 👇 www.biorxiv.org/content/10.1...
biorxiv.org
Uranium mining fuels evolution in deep groundwater microbiomes
Microbial communities in the deep biosphere underpin global biogeochemical cycles, yet their evolutionary responses to extensive anthropogenic disturbances remain unclear. Uranium in-situ leaching (IS...
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The Probst Lab @probstlab.bsky.social · 31/07/2025
Please RT this awesome opportunity to do a PhD at @unidue.bsky.social in collaboration with @jgi.doe.gov!! 🔥 Thanks!
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The Probst Lab @probstlab.bsky.social · 16/07/2025
We’re happy to announce Dr. Lennard Stach!! 🥳🥳 Well done Lennard for a brilliant defense and thesis!! We will miss you! Finally, thank you @leeselab.bsky.social for sitting in the thesis committee! 🫶
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The Probst Lab @probstlab.bsky.social · 13/06/2025
Our @umweltstiftung.bsky.social fellow Linda Labecka presented her work at the most recent DBU conference! She works closely with the Institute for Artificial Intelligence in Medicine (@unidue.bsky.social & University Medicine Essen) and Universitätsklinikum Bonn (@unibonn.bsky.social)! 🧬💻
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The Probst Lab @probstlab.bsky.social · 04/06/2025
Our latest work is out - here, our own Dr. Sarah Eßer compares transcriptomic patterns of Altiarchaeum in Crystal Geyser (US) and the Muehlbacher sufidic spring (Germany)! 🧬 Read more below: enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
enviromicro-journals.onlinelibrary.wiley.com
Differential Expression of Core Metabolic Functions in Candidatus Altiarchaeum Inhabiting Distinct Subsurface Ecosystems
Major differences between Candidatus Altiarchaeum species living in two distinct subsurface ecosystems as determined via metatranscriptomics. Genes overly expressed in different Ca. Altiarchaea in Mu...
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The Probst Lab @probstlab.bsky.social · 30/05/2025
Excited to welcome @hsintunglai.bsky.social and @renaandraes.bsky.social as PhD students to our group!! They will be working within Phase 2 of @crc-resist.bsky.social @unidue.bsky.social under the supervision of @alexjprobst.bsky.social and @cristinamoraru.bsky.social.
media.tenor.com
a person in a lab coat with the word let 's do this
ALT: a person in a lab coat with the word let 's do this
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The Probst Lab @probstlab.bsky.social · 03/04/2025
#TBT to @joernstarke.bsky.social and @katharinasures.bsky.social presenting their amazing work at the @vaam-microbes.bsky.social AC 2025 which took place at @ruhr-uni-bochum.de just last week! Well done you two! @crc-resist.bsky.social @unidue.bsky.social
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The Probst Lab @probstlab.bsky.social · 31/03/2025
Here's our latest group photo! Our lovely team keeps growing, as does our enthusiasm for doing great science together! 🦠🧬
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The Probst Lab @probstlab.bsky.social · 24/03/2025
We’re looking forward to meeting all our science friends at the @vaam-microbes.bsky.social Annual Conference 2025 at @ruhr-uni-bochum.de !! 🧬🦠 On our side, we’re exceptionally giving two talks about our latest work: ⬇️
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The Probst Lab @probstlab.bsky.social · 17/03/2025
Super happy to be hosting Prof. Richard Allen White III AKA @raw937.bsky.social from the University of North Carolina at Charlotte at @unidue.bsky.social for 3 surprisingly sunny weeks!! Great to have you around Rick!! 🦠🧬
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The Probst Lab @probstlab.bsky.social · 11/03/2025
Want to know who’s replicating and who’s just hanging out in your enrichment cultures? Our new study led by @soansi.bsky.social shows how @nanoporetech.com long-read sequencing can reveal replication states, shedding light on microbial growth. 🦠🧬 See our latest publication: doi.org/10.1093/isme...
doi.org
Inferring replication states of bacteria and viruses in enrichment cultures via long-read sequencing
Abstract. Most microorganisms cannot be cultured in isolation, necessitating sophisticated methods for studying their (eco)physiology. While numerous appro
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The Probst Lab @probstlab.bsky.social · 20/02/2025
Is stress response in stream sediments uniform across catchments? 🌊🦠 With @TheWrightonLab at CSU, we built river MAG & gene DBs and used metaT data to explore this while uncovering active stream microbiome metabolic functions! Read our preprint here: doi.org/10.1101/2025... @unidue.bsky.social
doi.org
A uniform stress response of stream microbiomes in the hyporheic zone across North America
Background Stream hyporheic zones represent a unique ecosystem at the interface of stream water and surrounding sediments, characterized by high heterogeneity and accelerated biogeochemical activity. ...
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The Probst Lab @probstlab.bsky.social · 20/02/2025
Quick PSA: we’ve officially deactivated our profile on Twitter/X and will henceforth only use Bluesky to communicate our science 😁
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The Probst Lab @probstlab.bsky.social · 13/01/2025
We’re kicking off our Archean Park ERC project at @uni-muenster.de with @alexjprobst.bsky.social Jens Kallmeyer, Ivan Berg and Kai-Uwe Hinrichs & respective groups! Thanks very much to @donatogiovannelli.bsky.social and Prof. William Martin for giving invited talks to get us started!
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cristinamoraru.bsky.social @cristinamoraru.bsky.social · 20/12/2024
@probstlab.bsky.social @crc-resist.bsky.social #1 on virus-host stress response in rivers tinyurl.com/43cjd6es #2 on microbial & epigenetic stress response in rivers tinyurl.com/bdf8eu5a @alexjprobst.bsky.social @unidue.bsky.social Pls RT!
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André Soares @geomicrosoares.bsky.social · 20/12/2024
We're hiring two bioinformatics-focused PhD students - one on microbial & epigenetic stress response in rivers, another on virus-host stress response in rivers! 🧬🦠💻 @unidue.bsky.social @cristinamoraru.bsky.social Please RT & spread the word - the @probstlab.bsky.social awaits you! 🦸 @idw-online.de
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Daniel Hering @danielheringude.bsky.social · 19/12/2024
Interested in multiple stressor research in rivers? Interested in a PhD under excellent supervision in one of Europe’s largest freshwater research centres? We seek 8 doctoral researchers for the CRC RESIST at the University of Duisburg-Essen! sfb-resist.de/people/open-... #rivers #PhDjobs
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The Probst Lab @probstlab.bsky.social · 19/12/2024
We’re hiring!! Come do a PhD with us using -omics to better understand river microbiomes responses to drought processes! ⬇️
media.tenor.com
kermit the frog is standing behind a red curtain .
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Alex Probst @alexjprobst.bsky.social · 19/12/2024
#PhD #position #alert 2 bioinfo PhD positions @ProbstLab @RESIST_CRC #1 on microbial & epigenetic stress response in rivers tinyurl.com/bdf8eu5a #2 on virus-host stress response in rivers tinyurl.com/43cjd6es (supervision Moraru) Please share!
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The Probst Lab @probstlab.bsky.social · 12/12/2023
We are grateful for the privilege of hosting Sigrid Neuhauser @sigridneuhauser.bsky.social today. She delivered a fascinating talk about her work on Phytomyxids. As part of the university network AURORA she currently visits the ProbstLab to foster scientific cooperations. 🥬🧬🥦
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