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Matt Sampson

@kidneyomicsamps.bsky.social
1.6K followers 959 following 167 posts

Pediatric nephrologist at Boston Children’s Hospital. Obsessed w/genomics to discover causes & cures for pediatric kidney disease #Kidneyomics Sampsonlab.org

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Reposted by Matt Sampson
Simone Sanna-Cherchi 🧬 @genetickidneydoc.bsky.social · 11/03/2026
Online today on @jamanetworkopen.com our new paper on the role of #APOL1 M1 in increasing precision diagnosis for CKD in individuals from African ancestry. Collaboration with @kidneyomicsamps.bsky.social @gbadegesinlab.bsky.social @kirylukk.bsky.social et al jamanetwork.com/journals/jam...
jamanetwork.com
Precision Diagnosis in APOL1 Kidney Disease With p.N264K M1 Protective Variant
This case-control study evaluates whether, in patients with APOL1 high-risk genotype kidney disease with at least 1 G2 allele, M1 can distinguish APOL1 chronic kidney disease from non-APOL1 chronic ki...
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Matt Sampson @kidneyomicsamps.bsky.social · 21/01/2026
🚀 Multiple open post-doc positions in our lab If you're a driven scientist with a strong interest in human genomics related to kidney disease & want to advance genetic discoveries, therapeutic hypotheses, & precision medicine for them, I hope you apply! tinyurl.com/kidneyomics-...
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Gabriel Cara Fuentes @carafuentes-neph.bsky.social · 14/01/2026
In 2020, we started to question whether #idiopathicnephroticsyndrome is strictly a 'pure' podocytopathy. Today, I am happy to share our new manuscript proposing a role of the glomerular endothelium in the disease pathogenesis. urldefense.com/v3/__https:/...
urldefense.com
Endothelial cell–released CD93 contributes to podocyte injury in idiopathic nephrotic syndrome
Soluble CD93 contributes to podocyte injury, and CD93 blockade emerges as a candidate therapeutic target in INS.
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Stefano Da Sacco @stefanodasacco.bsky.social · 14/01/2026
From a chance encounter years ago, far away, to this milestone today. Proud to have been involved in this research! Breakthroughs happen when we share ideas and challenge paradigms. Science moves forward when we work together—and this is just the beginning. #Nephrology #Research #TeamScience
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dongwon-lee.bsky.social @dongwon-lee.bsky.social · 14/01/2026
Thanks for doing this, Matt! I am so excited to get this out finally!
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Matt Sampson @kidneyomicsamps.bsky.social · 14/01/2026
Supervised by @dongwon-lee.bsky.social we're excited to share our preprint on the landscape of allele-specific expression (ASE) in human kidneys. Using paired WGS and RNA-seq from kidney biopsies, we mapped ASE in proteinuric kidney disease in the #NEPTUNE study www.biorxiv.org/content/10.6...
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Janewit Wongboonsin @janewit-thekidgene.bsky.social · 13/01/2026
A long engaging and amazing journey for me in Kidney Genetics !!
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Matt Sampson @kidneyomicsamps.bsky.social · 12/01/2026
In 2021 @janewit-thekidgene.bsky.social joined our lab & decided to define the prevalence & clinical correlates of known genetic forms of nephrotic syndrome among an unselected group of adults. 5 yrs later, we're excited to share what he found; a 🧵 kidney-international.org/article/S008...
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Matt Sampson @kidneyomicsamps.bsky.social · 05/01/2026
The 9th-11th annual “Conferences on The Nephrotic Syndrome” took place from 1957-1959 & I am privileged to have their Proceedings. From the library of Dr. David Cornfeld to Bernard Kaplan to now me. The topics still resonate, check out the ‘57 ToC. Looking forward to sharing excerpts from in ‘26
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Matt Sampson @kidneyomicsamps.bsky.social · 19/12/2025
Dr. Nuno Loureiro, the MIT Physicist murdered this week, was a neighbor in Brookline whose daughters are in the same schools as my own kdis. We are all saddened by his loss. A GoFundMe has been established to support his children. Please consider donating if you can. gofund.me/f1657ba10
gofund.me
Donate to In Loving Memory of Nuno Loureiro, Supporting His Family, organized by Iva Konieczka
With heavy hearts, we share this page on behalf of the Loureiro… Iva Konieczka needs your support for In Loving Memory of Nuno Loureiro, Supporting His Family
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Majmundar Laboratory @majmundarlab.bsky.social · 11/12/2025
Genes regulate kidney stones. In our recent editorial, Ken Saida and I review the evolving landscape of Mendelian genetics in KSD and discuss findings from a large cohort analysis in cJASN: doi.org/10.2215/CJN.... @harvardmed.bsky.social @bostonchildrens.bsky.social
doi.org
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Majmundar Laboratory @majmundarlab.bsky.social · 11/12/2025
Great collaboration with Florian Buerger, Friedhelm Hildebrandt, Jim Fawcett, @kidneyomicsamps.bsky.social, Markus Rinschen and many others. Huge thanks to all of our students who contributed so much to this work. #raredisease #nephrology #nephtwitter #medtwitter #kidney #fsgs
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Matt Sampson @kidneyomicsamps.bsky.social · 11/12/2025
Excited to make a small contribution to this great work by my @bostonchildrens.bsky.social Peds Neph colleague @majmundarlab.bsky.social. He is doing amazing work to tease out the genetic drivers & molecular mechanisms of rare pediatric kidney dz while also directing our Kidney Genetics Clinic
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Matt Sampson @kidneyomicsamps.bsky.social · 05/11/2025
Sad that I can’t take my littlest podocyte to #KidneyWk with me. Can’t quite get the zipper to close @thesampsonlab.bsky.social
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Matt Sampson @kidneyomicsamps.bsky.social · 05/11/2025
Ahead of #KidneyWk25, I’m recruiting 2-3 folks to help us map the genomics of pediatric kidney diseases toward treatments & cures. Please reach out if you’d like to connect in Houston @bostonchildrens.bsky.social @asnkidney.bsky.social @harvardmed.bsky.social @broadinstitute.org sampsonlab.org
sampsonlab.org
Sampson Lab for Kidney Genomics
The Sampson Lab for Kidney Genomics, a research lab at Boston Children's Hospital's Division of Nephrology, seeks to discover causes, treatments, and cures of nephrotic syndrome through genomics. We b...
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 14/10/2025
We’re excited to share that the Sampson Lab and Dongwon Lee Labs will be at ASHG 2025! 🎉 This year, our team is presenting 7 posters, and we can’t wait to connect, learn, and exchange ideas. If you’re attending, come check out our posters! #ASHG2025 @kidneyomicsamps.bsky.social
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Matt Sampson @kidneyomicsamps.bsky.social · 14/10/2025
Our team is excited to meet folks at #ASHG25 #kidneyomics
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Struan Grant @struangrant.bsky.social · 14/10/2025
Our #ASHG25 platform activities: Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11 Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15 Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15 Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11
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Matt Sampson @kidneyomicsamps.bsky.social · 29/09/2025
Like many, I'm faced with having to resubmit a well scored RO1 (8th%ile to NIDDK on proteinuric kidney dz multiomics) My question: Can/should I share the A0 percentile in the 1 page intro to resubmission? Or is there some rule/convention against this? I can just share supportive quotes too
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Janewit Wongboonsin @janewit-thekidgene.bsky.social · 19/07/2025
🧬Introducing our first-ever handbook of genetic nephrology, with free download until 8/2025 authors.elsevier.com/a/1lSgWzcYo6... @andrewmallett8.bsky.social and I saw a gap in foundational reading of genetic nephrology and decided to gather articles that clinician and learners can all enjoy
authors.elsevier.com
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Janewit Wongboonsin @janewit-thekidgene.bsky.social · 19/07/2025
We have 14 chapters covering 1️⃣ Clinical approaches to genetic kidney diseases 2️⃣ Core and relevant concepts in genetics 3️⃣ Research, implementation & med-ed in this growing field Big thanks to Dr. Bonventre and my incredible mentor @kidneyomicsamps.bsky.social for the opportunity and support. 🙏
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 27/05/2025
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 04/06/2025
Why does your DNA matter?🧬 Because it holds clues that can unlock answers, not just for your child’s care, but for families everywhere facing nephrotic syndrome. 💙 Swipe to see how your sample can spark change. #thesampsonlab #nephroticsyndrome #DNA #raredisease
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 30/04/2025
Yesterday, Matt Sampson and Kathy Madrazo represented our team at the Boston Children’s Hospital Pediatric Rare Disease Summit. Matt Sampson, Pediatric Nephrologist and Principal Investigator, spoke on a panel about the critical role of language accessibility in enhancing care and research.
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 30/04/2025
Kathy Madrazo, Pediatrician and Clinical Research Specialist, presented on the power of biobanking and genomic research, highlighting insights from our BIGKiDs Study. @kidneyomicsamps.bsky.social
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 18/04/2025
Principal Investigator. Pediatric Nephrologist. On a mission to find a cure for nephrotic syndrome. Now in action figure form. @kidneyomicsamps.bsky.social
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Simone Sanna-Cherchi 🧬 @genetickidneydoc.bsky.social · 12/04/2025
Congrats to Elena Martinelli for being selected among @columbiamed.bsky.social top postdocs to present her research on #APOL1 and the value of the protective M1 variant at Medicine Grand Rounds. #FSGS #genetics @apollonetwork13.bsky.social @gbadegesinlab.bsky.social @kidneyomicsamps.bsky.social
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Matt Sampson @kidneyomicsamps.bsky.social · 13/04/2025
Where to go for a nice post-NKF brunch with @ksusztak.bsky.social ? To a spot whose acronym they use for marketing represents what the two of us are trying to stamp out using #kidneyomics 🧬🫘
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 02/04/2025
Happy National #ChildrensBookDay! 📚 @kidneyomicsamps.bsky.social
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Shematologist, MD @shematologist.medsky.social · 01/04/2025
Someone get him a nephrologist @kidneyboy.bsky.social @kidneyomicsamps.bsky.social @caulimovirus.bsky.social @therealdoctort.bsky.social
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Matt Sampson @kidneyomicsamps.bsky.social · 19/03/2025
sjobs.brassring.com/TGnewUI/Sear... Come be @thesampsonlab.bsky.social Social Media & Community Outreach Coordinator. I am VERY interested in applicants bilingual in Spanish. We're growing by leaps and bounds & there are lots of opportunities to bring your own ideas. Please repost
sjobs.brassring.com
Social Media Coordinator - Sampson Lab - Boston Childrens Hospital - Job Details
Job Details: The Sampson Lab for Kidney Genomics at Boston Children’s Hospital/Harvard Medical School is dedicated to uncov
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 11/03/2025
Lily McCloskey, a student research assistant from last summer, reflects on her time working with our lab. Our team, made up of individuals from diverse backgrounds, fosters an inclusive environment where everyone can thrive. Watch the full video here: buff.ly/2vkENNY @kidneyomicsamps.bsky.social
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Matt Sampson @kidneyomicsamps.bsky.social · 08/03/2025
www.wpbf.com/article/sat-... Also was an issue here in Brookline, MA
wpbf.com
SAT glitch disrupts tests at local high schools
A nationwide SAT glitch affected students at Martin County High School and South Fork High School.
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Matt Sampson @kidneyomicsamps.bsky.social · 08/03/2025
(1/2)😡My daughter sat for SATs today & the @collegeboard SAT software froze halfway through a Reading module. By the time an AV expert arrived and got it to work on another computer, she had 16 seconds remain. After, she had to do a Math module in this state, which worked for some reason
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Tom Sandora, MD MPH @tomsandora.bsky.social · 07/03/2025
A second measles death has now occurred (in New Mexico) in the ongoing outbreak. Weak and confusing messaging about the role of vaccination will only lead to more deaths. Vitamin A is not a substitute for vaccination - the MMR vaccine is the only reliable way to prevent measles. #IDSky #PedsIDSky
nbcnews.com
Second measles death reported in ongoing outbreak
An unvaccinated adult in New Mexico tested positive for the measles virus after their death, the state Health Department said.
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 05/03/2025
Two weeks ago, Matt touched down in Cape Town, South Africa, to attend the IPNA Congress. Thanks to everyone who presented and made it a great trip! #IPNA2025 @kidneyomicsamps.bsky.social
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 04/03/2025
QOTD: Who on the team would be your emergency contact? @kidneyomicsamps.bsky.social
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 03/03/2025
It’s #KidneyMonth! Here are some memes to kick it off. @kidneyomicsamps.bsky.social
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 26/02/2025
With over 6,000 identified rare diseases, we are fortunate to have doctors and researchers around the globe working to learn more about nephrotic syndrome. #RareDiseaseDay #nephrology #computationalbiology #kidneyomics @kidneyomicsamps.bsky.social
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Annika Barber @annikabarber.bsky.social · 24/02/2025
Wondering if your study section cancelled? I update this sheet daily. As of today, 56/124 study sections that should have met since Jan 2, 2025 have "not met as scheduled." docs.google.com/spreadsheets...
docs.google.com
2025 Study section tracking
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Matt Sampson @kidneyomicsamps.bsky.social · 24/02/2025
“Dear Applicant,  The GHD study section meeting scheduled for today and tomorrow, is not occurring on these dates.  It is being postponed to later dates, to be determined.  This is because the meeting has not yet posted in the Federal Register.  I do not know when the meeting will be rescheduled..."
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Michelle Rheault, MD @rheaultm.bsky.social · 23/02/2025
#EmailsToDOGE 1. Spoke about Alport syndrome to international audience at #IPNA2025 2. Peer reviewed manuscripts x2 3. Cared for children with kidney disease 4. Review clinical trial enrollment and lab results 5. Brought my daughter to South Africa to learn about effects of apartheid first hand 🇿🇦
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Matt Sampson @kidneyomicsamps.bsky.social · 23/02/2025
This is the best article I’ve read so far in terms of describing the challenges impacting research in the US. I am being directly affected already. My RO1 is due to be reviewed on Monday but the study section is likely to be canceled. This will have a profound impact on our lab’s work #kidneyomics
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 21/02/2025
Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at: 5calls.org
5calls.org
5 Calls
Spend 5 minutes. Make 5 calls. Make your voice heard.
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Dr Louise Oni @louiseoni.bsky.social · 19/02/2025
A great evening meeting the phenomenal @kidneyomicsamps.bsky.social & our great Oz colleagues including @cathyquinlan.bsky.social #IPNA2025
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Dr Louise Oni @louiseoni.bsky.social · 19/02/2025
Incredible to meet & I look forward to collaborating to bring benefit to children globally
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Sampson Lab for Kidney Genomics @thesampsonlab.bsky.social · 19/02/2025
📍Cape Town, South Africa 🇿🇦 Matt is at the 2025 International Pediatric Nephrology Association (IPNA) Congress in Cape Town, South Africa, where experts are coming together to learn, connect, and push the boundaries of pediatric nephrology. #IPNA2025 @kidneyomicsamps.bsky.social
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Matt Sampson @kidneyomicsamps.bsky.social · 19/02/2025
So great to spend some time chatting about pediatric nephrology and life with @louiseoni.bsky.social Great to meet folks who I admire at @ped-neph.bsky.social
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Joseph Flynn, MD @jostflynnmd.bsky.social · 17/02/2025
With 3 former division heads, no less! Note the huge smiles! #nephsky #medsky
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