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Reposted by Kei Sakamoto

European Association for the Study of Diabetes @easdnews.bsky.social · 16/07/2026

🏆 We are honoured to announce Prof. Kei Sakamoto (@ucph.bsky.social) as the recipient of the #EASD - Novo Nordisk Foundation #Diabetes Prize for Excellence 2026! Learn more 👉 www.easd.org/prizes/easd-... We look forward to his prize lecture & honouring him at #EASD2026 in Milan👏

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Reposted by Kei Sakamoto

NNF Center for Basic Metabolic Research @cbmr.science · 07/04/2026

We are delighted to learn that Vice Executive Director Professor @keisakamoto.bsky.social has been elected a Fellow of the @royalsoced.bsky.social! He says: "I am deeply honoured to be elected as a Fellow of the Royal Society of Edinburgh ... It inspires me to keep pursuing meaningful science."

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Reposted by Kei Sakamoto

Rune Busk Damgaard @rbdamgaard.bsky.social · 16/02/2026

🧐 What if metabolic defects are not just a consequence of inflammatory disease - but actively contribute to it? Inflammation and metabolism are deeply intertwined, but the molecular links remain unclear. Our new paper in Cell Death & Differentiation uncovers one. 🧵👇 nature.com/articles/s41...

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Reposted by Kei Sakamoto

Sakamoto Lab @labsakamoto.bsky.social · 09/09/2025

The structure of BAY-3827 with wild-type AMPK α2 kinase domain by @zeqiraj.bsky.social & postdoc Mohd. Syed Ayengar helped determine the mechanism of action of this compound and the limitations for its use, addressing a long-standing challenge in the field: the absence of specific AMPK inhibitors.

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Reposted by Kei Sakamoto

Sakamoto Lab @labsakamoto.bsky.social · 09/09/2025

Latest publication from the lab spearheaded by @shoreseashell.bsky.social & in collaboration with @zeqiraj.bsky.social is out. Using structural, biochemical & computational tools, this work sheds light on the mechanism of action of BAY-3827 in inhibiting #AMPK 1/3 www.science.org/doi/full/10....

science.org

Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827

The mechanism and unique molecular/cellular features of the potent and selective AMPK inhibitor BAY-3827 are unraveled.

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Reposted by Kei Sakamoto

Juleen R. Zierath @juleenrzierath.bsky.social · 11/07/2025

Obesity is a global public health concern closely linked to cardiometabolic complications. This Comment provides views on recent breakthroughs, emerging innovations and future needs of therapeutic interventions to counteract obesity and its associated health risks. www.nature.com/articles/s42...

nature.com

Shaping the future of cardiometabolic innovation: advances and opportunities - Nature Metabolism

Obesity is a global public health concern closely linked to cardiometabolic complications. This Comment provides our views on recent breakthroughs, emerging innovations and future needs of therapeutic...

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Kei Sakamoto @keisakamoto.bsky.social · 23/05/2025

Happy to have contributed to this very interesting work ked/driven by Raid Nisr, Alison McNeilly and Graham Rena (University of Dundee). doi.org/10.1111/apha...

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Reposted by Kei Sakamoto

Sakamoto Lab @labsakamoto.bsky.social · 16/05/2025

Special day for our group @cbmr.science as we celebrate the successful defense of our (first) freshly minted PhD, Dr. Conchita Bringas 🥳 Her thesis was based on characterizing novel #AMPK inhibitors. Special thanks to the great committee @rbdamgaard.bsky.social ,Dave Carling & Lykke Sylow.

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Reposted by Kei Sakamoto

Eric Topol @erictopol.bsky.social · 20/04/2025

The surprising result for a GLP-1 pill (orforglipron) is the magnitude of weight loss in a Phase 3 trial of participants with Type 2 diabetes. For still unexplained reasons, people with diabetes lose much less weight on GLP-1 drugs than those with obesity, w/o diabetes.

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Kei Sakamoto @keisakamoto.bsky.social · 21/04/2025

Th most-cited research papers of all time. A 1951 publication by US biochemist Oliver Lowry in the Journal of Biological Chemistry describing an assay to determine the amount of protein in a solution has been cited more than 350,000 times.

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Kei Sakamoto @keisakamoto.bsky.social · 21/04/2025

Eli Lilly announced positive results from a large clinical trial of its once-daily pill orforglipron in people with type 2 diabetes, while Pfizer announced last week it was halting development of its candidate after signs of liver injury in a trial participant.

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Kei Sakamoto @keisakamoto.bsky.social · 18/04/2025

Joan was a visionary and inspirational leader, researcher and generous mentor and friend. His legacy will stay forever. @irbbarcelona.org

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Reposted by Kei Sakamoto

Science Magazine @science.org · 26/03/2025

President Donald Trump has nominated Susan Monarez, an infectious disease researcher and current acting director of the Centers for Disease Control and Prevention, to become the agency’s permanent leader. scim.ag/425J0xs

scim.ag

Trump’s new CDC pick ‘has her work cut out for her’

Susan Monarez, an expert in biosecurity and infectious disease, strikes some as a sensible choice to head the health agency—but some staffers there have raised concerns

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Reposted by Kei Sakamoto

Mark Cuban @mcuban.bsky.social · 22/03/2025

From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

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Reposted by Kei Sakamoto

BrunetLab @brunetlab.bsky.social · 22/03/2025

Interested in aging? Super excited about this upcoming Keystone meeting!! 🧪🌲🌲 Aging: Immune Function and Organ Health -- Banff, Canada in 2026!!! ✨✨ Joint meeting with the Keystone Innate Immunity meeting! #aging #immunity @keystonesymposia.bsky.social www.keystonesymposia.org/conferences/...

keystonesymposia.org

Aging: Immune Function and Organ Health | Keystone Symposia

Join us at the Keystone Symposia on Aging: Immune Function and Organ Health, March 2026, in Banff, with field leaders!

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Reposted by Kei Sakamoto

Anna Krook @annakrook.bsky.social · 21/03/2025

The Strategic Research Programme in Diabetes at Karolinska Institutet and Umeå Univeristy is seeking a Programme Manager (based in Stockholm). More information about the programme is here ki.se/en/srp-diabe... and the link to the position is here ki.varbi.com/en/what:job/... Please repost!

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Kei Sakamoto @keisakamoto.bsky.social · 21/03/2025

Thank you very much for this initiative and providing us with the opportunity to share our memories and stories. His legacy will stay forever. Visionary and inspirational leader, researcher and generous mentor and friend.

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Reposted by Kei Sakamoto

Eric Topol @erictopol.bsky.social · 13/03/2025

More than 2 decades ago the PINK1 protein was found to be linked to Parkinson's disease, but its structure and how it was activated was not known. Until @science.org today. A triumph for cryo-EM and structural biology, introducing new targets for drug intervention. www.science.org/doi/10.1126/...

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Kei Sakamoto @keisakamoto.bsky.social · 12/03/2025

"Glycogen drives tumour initiation and progression in lung adenocarcinoma"

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Reposted by Kei Sakamoto

Sakamoto Lab @labsakamoto.bsky.social · 11/03/2025

Strong presence of the @labsakamoto.bsky.social group members at the Metabolism Day #MD25 @cbmr.science Posters were presented by postdocs Joy & Jordana and by PhD students Maria, Hongling, Conchita & Costanza. #AMPK #TFEB #SIK

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Reposted by Kei Sakamoto

Science Magazine @science.org · 11/03/2025

A special issue on #WomensHealth in #ScienceAdvances highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Learn more: scim.ag/3R59fPe (THREAD 🧵)

Science Advances’ special issue on women’s health highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Articles cover a range of studies from the interplay between menopause and Alzheimer’s risk to the menstrual cycle’s influence on the brain-heart connection. It also describes the opportunities pregnancy provides to research aspects of both physical and mental health. By prioritizing women’s unique physiological and psychological experiences, research can expand the frontiers of knowledge in ways that benefit everyone.

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Reposted by Kei Sakamoto

Sakamoto Lab @labsakamoto.bsky.social · 10/03/2025

Our group @cbmr.science is now driven by an all women workforce (barring Kei), & we are incredibly fortunate to have these (multi)talented, hard working & generous women who support & elevate each other every day! Happy International Women's Day! #WomensDay2025 #LatePost

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Reposted by Kei Sakamoto

Science Magazine @science.org · 08/03/2025

Currently, NIH's Center for Scientific Review reviews 66,000 grant applications a year, with panels run by NIH’s separate institutes reviewing the rest. Under a new plan, the institute-run panels will be eliminated, and many of the scientists overseeing them will be laid off. scim.ag/3QP0FUG

scim.ag

NIH will eliminate many peer review panels and lay off some scientists overseeing them

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Reposted by Kei Sakamoto

Science Magazine @science.org · 08/03/2025

"The academic structure … makes planning for a family feel like an impossible luxury." In this #ScienceWorkingLife, two postdocs share how, as women in academia, having children can feel impossible—and how talking about it makes them feel less alone. scim.ag/3F60VMt #InternationalWomensDay

scim.ag

As women in academia, having children can feel impossible. Talking about it makes us feel less alone

The struggle is “balancing their careers not just with motherhood, but with what comes before: relationships and planning for a family,” these postdocs write

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Kei Sakamoto @keisakamoto.bsky.social · 06/03/2025

Pleased to share our new preprint describing mechanistic insights and cellular selectivity of the AMPK inhibitor.

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