The South African National Department of Health have set ambitious targets to scale up TB testing, focusing primarily on clinic attendees. In the context of declining funding for TB care and preventio...

Age at TB diagnosis in Zimbabwe increased between 2000 and 2024. TB programmes must adapt case-finding, clinical services and management for older adults considering multimorbidity, polypharmacy and f...

Background Sex differences in Mycobacterium tuberculosis (Mtb) exposure likely contribute to sex differences in tuberculosis (TB) burden. However, population-level age- and sex-specific patterns of Mt...

A modelling analysis at a global scale estimates that three interventions (vaccination, community-wide screening and prison screening programmes) could prevent more than 10% of tuberculosis cases betw...

This case study highlights how LIGHT addressed these challenges through gender-responsive and equity-focused research across Kenya, Malawi, Nigeria and Uganda. LIGHT combined primary and secondary

The South Africa National Department of Health have set ambitious targets to scale up TB testing, focusing primarily on clinic attendees. In the context of declining funding for TB care and prevention...

The infant tuberculosis vaccine, BCG, prevents severe tuberculosis disease, but protection is rarely durable beyond childhood. New tuberculosis vaccines are being developed for the prevention of infec...

Tuberculosis (TB) disproportionately affects low-income populations due to socioeconomic barriers. Conditional cash transfers (CCTs) are promising str…

YouTube video by LIGHT Consortium

Current efforts to reduce global tuberculosis incidence have proved insufficient, highlighting that urgent action is needed to address underlying modi…

In a systematic review and meta-analysis, Seyed Alireza Mortazavi and colleagues investigate urban versus rural differences in adult pulmonary tuberculosis prevalence between 2000 and 2024 in 26 low- ...

In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...

Hira Tanvir and colleagues estimate the potential impact of new tuberculosis vaccines under three scenarios of efficacy and conclude that to achieve the greatest impact, vaccines must prevent asymptom...

Several tuberculosis (TB) vaccines intended for adults and adolescents are in late-stage clinical trials, but there is limited research into how a new TB vaccine would be introduced. South Africa is a...

Epidemiological impact of heterogeneity in community screening for tuberculosis SUPERVISORY TEAM Supervisor Dr Katherine Horton...

Author summary Why was this study done? Infections caused by bacteria that are resistant to antibiotics are a major and growing threat to public health. Older adults and men are at higher risk of...

The WHO recommends the bedaquiline, pretomanid, and linezolid (BPaL) regimen with the additional fluoroquinolone antibiotic moxifloxacin (BPaLM) for initial treatment of multidrug- or rifampicin-resis...

Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...

Tuberculosis (TB) is a major public health concern and the leading infectious cause of mortality globally. The disease exhibits strong prevalence patterns by age and sex, but the implications of these...

Background Community-wide screening is a crucial strategy to end tuberculosis (TB), but a common concern is potential harm from overtreatment following false positive diagnoses. However, current refer...

PhD Project - New approaches for modelling tuberculosis transmission in low incidence settings at University of Bristol, listed on FindAPhD.com

Background: Tuberculosis (TB) prevalence is higher among men than women in low- and middle-income countries (LMICs). However, summary measures of sex difference