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Matthew Saunders

@mjsaunder.bsky.social
45 followers 58 following 21 posts

Public health physician and social epidemiologist passionate about addressing inequities in health and wellbeing through practice, research, and advocacy www.researchgate.net/profile/Matthe…

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Matthew Saunders @mjsaunder.bsky.social · 21/07/2026
Bedaquiline resistance is increasing globally and threatens to undermine efforts to end TB. In this cohort study from Uzbekistan, we describe the characteristics, treatment strategies, and long-term health outcomes of people with bedaquiline-resistant TB academic.oup.com/ofid/advance...
academic.oup.com
Characteristics, treatment strategies, and long-term health outcomes of people with bedaquiline-resistant tuberculosis in Karakalpakstan, Uzbekistan – a retrospective cohort study
AbstractBackground. Bedaquiline resistance is increasing globally, threatening effectiveness of short regimens for rifampicin/multi-drug resistant (RR/MDR)
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Tom Wingfield @tomwingfield.bsky.social · 23/06/2026
📢 Our new Thorax @bmj.com study. In England, 574 people with TB were diagnosed only after death, 2010–2022: ~𝗼𝗻𝗲 𝗽𝗲𝗿𝘀𝗼𝗻 𝗲𝘃𝗲𝗿𝘆 𝘄𝗲𝗲𝗸. Postmortem TB diagnosis is the ultimate diagnostic delay & should be a “never event”. 🔗 doi.org/10.1136/thor... @lstmnews.bsky.social Thanks @ukhsa.bsky.social
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Lara Goscé @laragosce.bsky.social · 13/06/2026
Poverty is a major driver of TB.Conditional cash transfers combined with counselling improve pre-treatment loss to follow-up.In this economic analysis our modelling projections show that this intervention is cost-effective and can reduce incidence and mortality. www.sciencedirect.com/science/arti...
sciencedirect.com
Cost-effectiveness of conditional cash transfers with pre- and post-test tuberculosis counselling in South Africa: a modelling analysis
Tuberculosis (TB) disproportionately affects low-income populations due to socioeconomic barriers. Conditional cash transfers (CCTs) are promising str…
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Matthew Saunders @mjsaunder.bsky.social · 02/06/2026
So...what would happen to the global TB epidemic if we "eliminated" undernutrition? Our paper out now @lancetgh.bsky.social, where we combined estimates from our review (academic.oup.com/ije/article/...) with population-specific BMI distributions to find out...(www.thelancet.com/journals/lan...
thelancet.com
Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study
Almost a quarter of global tuberculosis incidence in adults could be averted by eliminating undernutrition, approximately two-and-a-half times higher than current estimates. These findings highlight t...
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Tom Wingfield @tomwingfield.bsky.social · 19/05/2026
🧵 Our new @thelancet.com Regional Health Africa study from #SierraLeone: MORE THAN ONE IN FOUR PEOPLE WITH MDR/RR-TB DIED (𝟮𝟲%, 191/739) before treatment, during treatment, and to 12 months after "treatment success" (key figs 👇) TB care must extend beyond TB “cure”. 🔗 tinyurl.com/2p9zabwz #MDR-TB
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Finn McQuaid @cfmcquaid.bsky.social · 12/05/2026
So...what would happen to the global TB epidemic if we "eliminated" undernutrition? Our paper out now @lancetgh.bsky.social, where we combined estimates from our review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(www.sciencedirect.com/science/arti...)
sciencedirect.com
Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study
Current efforts to reduce global tuberculosis incidence have proved insufficient, highlighting that urgent action is needed to address underlying modi…
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Matthew Saunders @mjsaunder.bsky.social · 07/11/2025
Climate change and tuberculosis: www.thelancet.com/journals/lan.... Podcast with @cfmcquaid.bsky.social here: open.spotify.com/episode/28jr...
thelancet.com
Climate change and tuberculosis: an analytical framework
Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...
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Finn McQuaid @cfmcquaid.bsky.social · 31/10/2025
Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...
thelancet.com
Climate change and tuberculosis: an analytical framework
Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...
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The Lancet Infectious Diseases @thelancetinfdis.bsky.social · 28/10/2025
New comment: Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative www.thelancet.com/journals/lan...
thelancet.com
Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative
Undernutrition is a key driver of the global tuberculosis epidemic, increasing the risk of people developing tuberculosis disease and of poor outcomes in those who do.1 Each year, WHO publishes estima...
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Matthew Saunders @mjsaunder.bsky.social · 28/10/2025
“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say… Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...
thelancet.com
Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative
Undernutrition is a key driver of the global tuberculosis epidemic, increasing the risk of people developing tuberculosis disease and of poor outcomes in those who do.1 Each year, WHO publishes estima...
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Matthew Saunders @mjsaunder.bsky.social · 10/09/2025
So...what would happen to the global TB epidemic if we hypothetically "eliminated" undernutrition? In this preprint, we combined estimates from our new review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(doi.org/10.1101/2025...)
doi.org
Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study
Background Current efforts to reduce global tuberculosis incidence have proved insufficient, highlighting that urgent action is needed to address underlying modifiable risk factors such as undernutrit...
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Matthew Saunders @mjsaunder.bsky.social · 09/09/2025
Nutritional status is a key determinant of TB. In this updated systematic review and dose-response meta-analysis (43 cohorts inc > 26 million people) we redefined the relationship between body mass index (BMI) and TB. doi.org/10.1093/ije/...
doi.org
Body mass index and tuberculosis risk: an updated systematic literature review and dose–response meta-analysis
AbstractBackground. The relationship between nutritional status and tuberculosis is critically important but poorly understood. We extended a 2009 review c
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Matthew Saunders @mjsaunder.bsky.social · 12/08/2025
The global TB epidemic is driven by social determinants. In this case-control study in Peru, we characterised the associations between multidimensional household poverty, personal risk factors, and TB. @tb-lshtm.bsky.social idpjournal.biomedcentral.com/articles/10....
idpjournal.biomedcentral.com
The social determinants of tuberculosis: a case-control study characterising pathways to equitable intervention in Peru - Infectious Diseases of Poverty
Background Despite being key components of global tuberculosis policy, poverty reduction and social protection interventions have been inconsistently implemented. We aimed to characterise how poverty ...
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The Union @theunion.org · 07/08/2025
The Union's TB Undernutrition working group is hosting a webinar with Dr Matthew Saunders. 📅 21 August at 2pm CET Dr Saunders (@lshtm.bsky.social‬) will share findings from a new analysis that redefines the relationship between BMI and TB incidence. 📧 To join email membership@theunion.org.
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