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Julien Joseph

@jujoseph.bsky.social
50 followers 84 following 3 posts

Evolutionary biologist at Aarhus University, Denmark. Working on meiotic recombination, mutation, selection and genome evolution.

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Reposted by Julien Joseph
Laura Ross @laurarossevo.bsky.social · 08/09/2026
Ever wondered why diverse organism shrink their genome in specific cells? We try to make sense of these curious cases of programmed DNA elimination in a review that came out today @naturerevgenet.bsky.social trebuchet.public.springernature.app/get_content/... @sandraduharcourt.bsky.social
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Soni Lacefield @lacefieldlab.bsky.social · 21/08/2026
Excited to share this review that @needhibhalla.bsky.social and I wrote on meiotic checkpoints! www.annualreviews.org/content/jour...
annualreviews.org
Tuning Meiotic Checkpoints: Evolutionary Costs and Mechanistic Trade-Offs
In this review, we discuss three meiotic checkpoints—the DNA damage response, the pachytene checkpoint, and the spindle checkpoint—and highlight their similarities and differences across diverse syste...
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Colin Carlson @colincarlson.bsky.social · 10/08/2026
I wrote about a reason not to use generative AI in your writing that I haven't seen anyone talking about. Once I realized this, banning GenAI in our lab's writing became a no-brainer. Feel free to share, I think this is probably useful especially for trainees: www.carlsonlab.bio/thoughts/the...
carlsonlab.bio
The only reason you’ll ever need not to write with AI — The Carlson Lab
Over the last year, our lab has been developing a policy on AI use. To do this, we did three main things: We read a lot of academic publications and tech news. We set up an #ai channel on our la...
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Mario Vallejo-Marin @nicrodemo.bsky.social · 09/08/2026
Last year we took a small amber with a fossil bee to the Oxford synchrotron. Little did we know that it would become a tiny window into the ecology of bees and their mites in the subtropical forests 40 million years ago. @charliezoology.bsky.social @hfspo.bsky.social www.cell.com/iscience/ful...
cell.com
Insights into the ecology of early leaf-cutter bees revealed through synchrotron X-ray tomography
Zoology; Entomology; Evolutionary biology; Paleobiology
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Hervé Rogissart @herverogissart.bsky.social · 22/07/2026
🏔️🐟🧬 Excited to share my first PhD publication! We investigated how phenotypic plasticity, rapid selection, and genetic drift contribute to rapid phenotypic divergence in Arctic charr populations isolated for just over a century. Thanks to all my co-authors, collaborators, and reviewers! 😊
royalsocietypublishing.org
A century of allopatry: plasticity and rapid selection shape phenotypic trait variability under contrasting environments
Abstract. Allopatric isolation under contrasting environments can drive rapid phenotypic divergence, even over contemporary timescales. Rapid changes in mo
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Charles Mullon @charlesmullon.bsky.social · 03/08/2026
Looking for an Associate Prof position? Interested in behavioural ecology & cultural evolution? Come join us at the Dpt of Ecology and Evolution in Lausanne🇨🇭 @dee-unil.bsky.social @unil.bsky.social! Great department & great place to live. Pls RP. Apply here: wwwfbm.unil.ch/releve/appli...
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Claudia Astorino @claudistics.bsky.social · 04/08/2026
it’s #ToothyTuesday! some of my fav teeth are colugo lower incisors. these teeth are pectinate or “fan-like,” exhibiting many long, thin projections used for grooming! while colugos are sometimes called flying lemurs, they’re not actual lemurs: lemurs = primates, and colugos = dermopterans!
This image depicts the anterior, or front part, of the mandible, or lower jaw, of the colugo. The three incisors on each side of the jaw - especially the middle two teeth on each side of the jaw - are pectinate, or “fan-like” in form, with tooth crowns exhibiting many long, thin projections that colugos use for grooming. This photo was taken by Curious Sengi.
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Rosana Zenil-Ferguson @roszenil.bsky.social · 04/08/2026
Maybe late to the game, but if you have not read the 75th Anniversary special series of @systbiol.bsky.social you should. So many good ideas and history there academic.oup.com/sysbio/pages... #systematicbiology
academic.oup.com
Systematic Biology's 75th Anniversary
In celebration of Systematic Biology's 75th anniversary, the 2026 volume features a special series of discussions and essays commissioned by the Society’s Legac
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Reposted by Julien Joseph
Christian Landry @christianlandry.bsky.social · 04/08/2026
Our latest contribution on #regulatoryevolution in which we show that the shape of fitness functions and the distribution of mutational effect sizes jointly limit adaptation by regulatory mutations. Led by @simonaube.bsky.social www.nature.com/articles/s41...
nature.com
The shape of fitness functions and the distribution of mutational effect sizes jointly limit adaptation by regulatory mutations - Nature Ecology & Evolution
Saturation mutagenesis of the FCY1 promoter in budding yeast shows that adaptation to 5-fluorocytosine is not accessible through single cis-regulatory mutations, despite large mutational effects on pr...
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tomomi parins-fukuchi @tomopfuku.bsky.social · 16/06/2026
Excited to share my new paper in Syst Biol! academic.oup.com/sysbio/advan...
academic.oup.com
The Effects of Hemiplasy and Maintained Polymorphisms in Fossil Clades
Abstract. One of the most transformative advances in molecular systematics over the past several decades has been our understanding of how population proce
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Reposted by Julien Joseph
Priscilla Lau @prilau.bsky.social · 30/07/2026
Our paper (also, my first first-author paper) is now available in MEE early view! In this study, we introduced a state-dependent Ornstein-Uhlenbeck model we implemented in RevBayes to test adaptive hypotheses in macroevolution. (1/3) besjournals.onlinelibrary.wiley.com/doi/10.1111/...
besjournals.onlinelibrary.wiley.com
An efficient Bayesian phylogenetic approach for joint inference of continuous and discrete trait evolution under a state‐dependent Ornstein–Uhlenbeck model
Macroevolutionary adaptation of a continuous trait to different discrete states across species can be modelled using a phylogenetic state-dependent Ornstein–Uhlenbeck (OU) process. Existing infere...
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Caroline Farrior @cfarrior.bsky.social · 26/07/2026
Spread the word! My lab group is hosting a workshop tomorrow at #ESA2026: Ecological Theory for Everyone: A practical introduction to engaging with theory in your own research for those with little or no theoretical experience 1:30pm, Room 254B events.rdmobile.com/Sessions/Det...
A collage of theory figures: Trees searching for light, chaos from logistic growth, evolutionary analyses, stabilizing coexistence, and collective movement.
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Christian Landry @christianlandry.bsky.social · 08/07/2026
Our latest work on drug resistance and epistasis. We performed comparative deep mutational scanning of two fungal orthologs to estimate how much data on one can help predict the impact of mutations on the other. We dissect the source of epistasis at the atomic level. www.biorxiv.org/content/10.6...
biorxiv.org
Epistasis limits but does not prevent the transfer of mutation-drug resistance mapping across 600 million years of fungal evolution
Whether different pathogens acquire resistance to antimicrobials through the same mutations is a major question in evolution and microbiology. Most antifungal drugs are used to treat infections caused...
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Thibault (Tibo) Leroy @tiboleroyinen.bsky.social · 07/07/2026
Happy to share that Maëva Gabrielli's latest work on Zosterops borbonicus is now published in Evolution! Interested by identifying barrier loci with genomic data? I hope you will find this piece of work interesting! ⬇️ academic.oup.com/evolut/advan...
academic.oup.com
Accounting for recombination rate variation improves inference of barrier loci and reveals the role of both natural and sexual selection in an incipient bird radiation
Abstract. Examining genomic patterns of differentiation across lineage pairs at different stages of the speciation continuum, in combination with recombina
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Emiliano Martí 🇦🇷 @emilianomarti.bsky.social · 27/01/2026
Meiotic drive has long been considered as a genetic curiosity. Genomic "footprints" suggest otherwise. Check out our new review doi.org/10.1093/molb..., a cross-taxa synthesis arguing that recurrent drive is a pervasive and underappreciated force in genome evolution.
doi.org
The Evolutionary Genomics of Meiotic Drive
Abstract. Meiotic drivers are selfish genetic elements that gain transmission advantages by distorting equal, Mendelian segregation. For decades, biologist
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Benoit Nabholz @benoitevol.bsky.social · 07/07/2026
Very happy to have contributed to the study of the genomic differentiation of the British swallowtail butterfly (Papilio machaon britannicus). Despite the regular immigration of P. machaon from the nearby mainland, the British swallowtail butterfly remains genetically distinct. 1/..
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Guillaume Ramstein @guillramstein.bsky.social · 05/08/2025
Happy to share this review led by Janek Sendrowski, and written with Thomas Bataillon. We provided an overview of sequence-based AI models: what they can (and cannot) do, and what differentiates them from traditional techniques based on statistical associations link.springer.com/article/10.1...
link.springer.com
In silico prediction of variant effects: promises and limitations for precision plant breeding - Theoretical and Applied Genetics
Key message Sequence-based AI models show great potential for prediction of variant effects at high resolution, but their practical value in plant breeding remains to be confirmed through rigorous val...
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Julien Joseph @jujoseph.bsky.social · 07/07/2026
Hi everyone, I just started a bluesky account to share my work and keep up with the work of others :) ! I am very pleased to share this review on the evolutionary causes behind the existence of meiotic recombination hotspots: doi.org/10.1371/jour... I hope it will be useful to some of you!
doi.org
Why recombination hotspots?
Meiotic recombination is the process by which DNA is exchanged between parental chromosomes during the production of gametes in eukaryotes. This phenomenon has important implications for fertility, ge...
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