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Jonna Singh

@jonnasingh.bsky.social
758 followers 502 following 97 posts

Interoception, psychedelics, pain, flashy neurons, and everything in between prev basal ganglia and birds Postdoc @ Andermann lab

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Jonna Singh @jonnasingh.bsky.social · 26/08/2026
We're excited to present EASI-PASS! We can record the activity of many neurons, and separately, the expression of many genes. A natural next step for the field is to link these two types of information. 🧵👇 1/n
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Kanaka Rajan @kanakarajanphd.bsky.social · 07/08/2026
(1/8) Our approach for untangling brain-wide interactions is out today in @cp-neuron.bsky.social! Current-Based Decomposition (CURBD) uses RNNs constrained by real neural data to reveal the input driving neurons, uncovering how brain regions talk to each other. doi.org/10.1016/j.ne... 🧵👇
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Jonna Singh @jonnasingh.bsky.social · 27/07/2026
Favorite way to browse Bsky (:
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Lorenzo Posani @lorenzoposani.com · 15/07/2026
Out today on @nature.com! Connecting neural specialization, population geometry, and their functional implications across the cortical hierarchy. So grateful for this beautiful and fun collaboration with @shuqiw.bsky.social, S Muscinelli, L Paninski, and @stefanofusi.bsky.social!
nature.com
Rarely categorical, highly separable representations along the cortical hierarchy - Nature
Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.
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The Transmitter @thetransmitter.bsky.social · 01/06/2026
A hackathon reveals that disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data, write @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence www.thetransmitter.org/reproducibil...
thetransmitter.org
18 teams analyzed a neuro dataset and got different answers
Disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data.
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Jenna Norton @jenna-m-norton.bsky.social · 30/05/2026
Stopping Vought’s proposed rule will be critical to save science and future cures. @standupforscience.net created an action center to help you comment and contact Congress. Time to get loud! fight2win.standupforscience.net
fight2win.standupforscience.net
Stand up for Science
Stand up for Science
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Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 30/05/2026
If you are going to comment on the proposed changes to how science is done in the US, please use this guide. The rules specify that you have to mention the number associated with the proposed changes, and this blog has those. Here is where to comment: www.federalregister.gov/documents/20...
federalregister.gov
Regulation for Federal Financial Assistance
The Office of Management and Budget (OMB) proposes to revise the Guidance for Federal Financial Assistance to improve government- wide policies and requirements related to the management of grants, co...
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Jeremy Berg @jeremymberg.bsky.social · 30/05/2026
Ways to push back against the proposed OMB regulations fight2win.standupforscience.net
Front page from Stand Up for Science site regarding the proposed OMB regulations
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Carsen Stringer @computingnature.bsky.social · 22/05/2026
🚨🧠 Our paper is out! We introduce a simple computational model that generates macroscopic, long-timescale dynamics as seen in large-scale neural recordings. #neuroscience #dynamics @marius10p.bsky.social @zhong-lin.bsky.social @hhmijanelia.bsky.social Link: go.nature.com/4tRNjIu
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Ian Oldenburg @ianoldenburg.bsky.social · 19/05/2026
We are hiring a postdoc! We study neural activity and movement using holographic optogenetics, imaging, and recordings in awake mice. My first postdoc, Masashi, is starting his own lab, so now we have an opening. Seeking candidates excited about circuits, optics, coding, or ephys. oldenburglab.com
oldenburglab.com
Oldenburg Lab
Decoding the motor system through the use of multiphoton holographic optogenetics.
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Dr Kathleen Millen @neurodevkathy.bsky.social · 20/05/2026
🚨🧪🧵URGENT INPUT NEEDED: NIH asks input for next strategic plan-including emphasis on non-animal models (NAMs) to replace animals. Per NIH insider, anti-animal responses now outnumber scientists 200-700x. Please please provide input. Deadline: May 26, 11:59 PM ET. grants.nih.gov/news-events/...
grants.nih.gov
NIH Seeks Input on Framework for Next NIH-Wide Strategic Plan | Grants & Funding
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Sarah McAnulty, Ph.D. @sarahmackattack.bsky.social · 18/05/2026
I need your help. When I'm making projects happen, I don't have as much time to remind people to buy merch/donate to Skype a Scientist. SO our balance sheet is...oh dear 😅 If you're able, becoming a monthly donor, even a couple bucks a month, would be really amazing. givebutter.com/SupportSAS26
givebutter.com
Support Skype a Scientist!
By Skype a Scientist
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Paul Kristian LaFosse @lafosse.bsky.social · 15/05/2026
🚨 Ever wanted a simple way to control the activity of thousands of neurons? We introduce an all-optical raster photostimulation method to do just that! w/ @computingnature.bsky.social @marius10p.bsky.social #FluorescenceFriday #neuroskyence www.biorxiv.org/content/10.6... 1/n
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Madelyn Hjort @mmhjort.bsky.social · 06/05/2026
Thrilled to share our work out in @nature.com today! Linking flexibility modeling, single-cell imaging, and targeted optogenetics allowed us to characterize how some prefrontal neurons, and mPFC-VTA neurons in particular, drive contingency degradation behavior. www.nature.com/articles/s41...
nature.com
Prefrontal to ventral tegmental area dynamics drive contingency degradation - Nature
This work provides a mechanistic understanding of how certain prefrontal circuits in the rodent brain permit flexibility to selectively stop learned behaviours through interactions with core subcortic...
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Jonna Singh @jonnasingh.bsky.social · 30/04/2026
I love this idea so much
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Jeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026
Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
biorxiv.org
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Jonna Singh @jonnasingh.bsky.social · 11/03/2026
Eager to learn how one shanks a P10 rat with a neuropixels Very cool stuff
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Jonna Singh @jonnasingh.bsky.social · 06/03/2026
1) Why is this the first I’m learning about fish talking to each other by slapping their bellies 2) The actual results in this paper are awesome
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Jonna Singh @jonnasingh.bsky.social · 03/03/2026
how a small (~15) prolific and opinionated set of reviewers could steer a field over time This is great, and even these numbers underestimate the effect. Some fields have <10 qualified reviewers, one loud voice can tank or lift papers on its own
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Jason Moore @moorejh.bsky.social · 24/02/2026
Our perspectives piece on Agentic AI for biomedical research has been published in Nature Biotechnology www.nature.com/articles/s41... #agenticAI #artificialintelligence #agents
nature.com
Agentic AI and the rise of in silico team science in biomedical research - Nature Biotechnology
This study examines the emerging use of agentic artificial intelligence (AI) in biomedical research, highlighting the challenges and opportunities that may inform the design of agentic AI systems suit...
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Pat Savage @patrickesavage.bsky.social · 23/02/2026
Science has now published our eLetter responding to Rajendran et al., titled, “Data show that macaques do not synchronize to a beat” doi.org/10.1126/scie...
doi.org
Monkeys have rhythm
Synchronizing movements to music is a hallmark of human culture, but its evolutionary and neurobiological origins remain unknown. This ability requires (i) extracting a steady rhythmic pulse, or beat,...
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Jonna Singh @jonnasingh.bsky.social · 18/02/2026
For all the energy we use in developing new technologies and fancier data handling, this is an immediate, actionable problem that we need to prioritize Beautifully written!
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Yoav Livneh @yoavlivneh.bsky.social · 13/02/2026
New lab preprint! Can we study conscious perception of gut sensations in mice to reveal its neuronal basis? Can we train mice to report their gut sensations? Omer Rafael and Stav Shtiglitz in the lab teamed up to discover that…YES! Thread…1/6 www.biorxiv.org/content/10.6...
biorxiv.org
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Jonna Singh @jonnasingh.bsky.social · 12/02/2026
Almost feels wrong to see suite2p as a paper after all these years, used to it being a more of a silent pillar
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adamezracohen.bsky.social @adamezracohen.bsky.social · 04/01/2026
What is the computational role of dendritic excitations? Byung Hun Lee and team mapped voltage dynamics throughout the dendritic trees of CA1 pyramidal neurons in mice navigating in virtual reality. www.biorxiv.org/content/10.6...
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Yoav Livneh @yoavlivneh.bsky.social · 12/12/2025
lab preprint! Interopceptive predictions are central to many brain-body interactions theories, but it's unclear if/how they affect bodily physiology. We (fearless Einav Litvak et al) show that insular cortex predictions are essential for glucose homeostasis-THREAD.. www.biorxiv.org/content/10.6...
biorxiv.org
Insular cortex predictions regulate glucose homeostasis
Brain-body interactions are essential for physical and emotional homeostasis. The brain uses information from the external world to predict upcoming bodily changes. This process involves interoceptive...
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Alex Kwan @alexkwan.bsky.social · 05/12/2025
We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect. The full study is now online at Cell. @cp-cell.bsky.social Paper 👉 www.cell.com/cell/fulltex... Thread for a synopsis 👉 bsky.app/profile/alex...
cell.com
Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks
Psilocybin reshapes brain networks through activity-dependent plasticity, including a weakening of recurrent cortical loops that could underlie its therapeutic effects.
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The Transmitter @thetransmitter.bsky.social · 24/11/2025
In @thetransmitter.bsky.social’s Rising Stars of Neuroscience 2025, we recognize 25 early-career researchers who have made outstanding scientific contributions and demonstrated a commitment to mentoring and community-building in neuroscience. #neuroskyence #StateOfNeuroscience bit.ly/4rnFnyQ
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Jonna Singh @jonnasingh.bsky.social · 17/11/2025
Thanks @thetransmitter.bsky.social and to my lab for brightening my week with this rising stars in neuroscience award!! Wish I could be in #sfn to celebrate in the sun. Wonderful list of people: www.thetransmitter.org/early-career...
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Jonna Singh @jonnasingh.bsky.social · 02/11/2025
Woulda guessed 50%, glass half full kinda person
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Jeremy Berg @jeremymberg.bsky.social · 20/09/2025
ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS Comment period ends September 29th www.federalregister.gov/documents/20... 1/2
federalregister.gov
Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media
Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...
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Jonna Singh @jonnasingh.bsky.social · 17/06/2025
graphical abstract goes hard
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Mark Andermann @markandermann.bsky.social · 02/06/2025
Wild! Stephen, Praneel and their team use fluorescence lifetime imaging and various manipulations to show that, in male mice, both mating drive and hypothalamic tonic dopamine release drop after a successful mating and gradually recover over the next week, paralleling the recovery in sperm count.
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Jonna Singh @jonnasingh.bsky.social · 04/06/2025
Featuring 2p FLIM to track DA levels over days, and a demonstration that a neurons molecular identity is pretty labile @stephen-zhang.bsky.social @markandermann.bsky.social P.S: Praneel will be applying to MD PhD and is an absolute beast. Systems neuro labs don’t miss out!!
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Ecological Society of America @ecologicalsociety.bsky.social · 02/06/2025
URGENT! Contact your senators today to advocate to fund science agencies and programs! The Senate Appropriations Committee & its subcommittees are writing appropriation bills for the federal FY26 budget now. Here's how you can help: esa.org/esablog/2025...
the U.S. Capitol building on an overcast day, looking ominous
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Philip Ball @philipcball.bsky.social · 27/05/2025
I know it's not very helpful, but I find myself thinking about those who criticized Nature's and Scientific American's Harris endorsement on the grounds that "science should stay out of politics." I think about those people quite a lot.
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Jonna Singh @jonnasingh.bsky.social · 24/05/2025
It’s is practically guaranteed that what is happening to Harvard WILL happen to your favorite R1 institution if we don’t continue to engage our local representatives.
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Jonna Singh @jonnasingh.bsky.social · 23/05/2025
Reminder: Bluesky is an echo chamber. As useful as it is to get informed and feel support on here, it’s time to get uncomfortable and speak up *in real life*. Talk to those who are not here. Be ready to explain these catastrophes. Add YOUR grain of salt to the mobilization process. It matters.
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Jonna Singh @jonnasingh.bsky.social · 22/05/2025
Positional molecular markers guide the regeneration of the correct body parts in axolotls. Go axolotl gang!
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Carl T. Bergstrom @carlbergstrom.com · 18/05/2025
Under 65 years old? No Novovax COVID vaccine for you this year. As expected, the Republicans have enabled RFK Jr. and his coterie of antivax grifters to take away your right to make your own medical decisions in consultation with your doctor. Gift Link: www.nytimes.com/2025/05/17/h...
The new restriction will sharply limit access to the Novavax vaccine for people under 65 who are in good health. It may leave Americans who do not have underlying conditions at risk if a more virulent version of the coronavirus were to emerge. It could also limit options for people who want the vaccine for a wide array of reasons, including to protect a vulnerable loved one.
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Paul Bierman @paul-bierman.bsky.social · 16/05/2025
Dozens of responses to my essay summarized. 1. Why aren’t scientists in an uproar? 2. Most Americans don't know that defunding science will make their lives worse. Bluesky, tell your neighbors, science matters. Scientists, roar. 🧪💙📚 #scicomm #science 🌎 🔬 ⚒️ theconversation.com/unprecedente...
theconversation.com
Unprecedented cuts to the National Science Foundation endanger research that improves economic growth, national security and your life
The Trump administration has terminated hundreds of federal grants that support engineering, biology, geology, computer science, STEM education and much more.
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Jonna Singh @jonnasingh.bsky.social · 14/05/2025
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Grace Lindsay @neurograce.bsky.social · 12/05/2025
TOMORROW 12pm PT/3pm ET, academic workers across the country are organizing to call Senators and Representatives, particularly from historically “red” districts, to sign onto to letters supporting federal research funding. Register here to join the phonebank: form.laborbase.org/251246245216...
form.laborbase.org
Phonebank to Support Federal Research Funding on 5/13
Please click the link to complete this form.
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Jonna Singh @jonnasingh.bsky.social · 10/05/2025
Hardest surgery I’ve seen to get the coolest brainstem imaging I’ve seen! Rachel’s paper shows interoceptive information, in particular feeding-related info, is organized across PBN
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NIH Fellows United @nihfellowsunited.bsky.social · 09/05/2025
A thread: NIH Fellows United is committed to showing up, even when leadership won’t. 🧪
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Jonna Singh @jonnasingh.bsky.social · 06/05/2025
Pretty ironic that those who stand to gain the most from a quantitative arm are biologists given the reformatting of the field with new tech.
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Alt National Archives @altnatarchives.altgov.info · 04/05/2025
One of the most inspiring essays I’ve read on resistance. www.vnews.com/Column-A-tim...
vnews.com
Column: A time for bravery
It is no longer enough to be good; it is time to be brave.
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Brian Lovett @lovettbr.bsky.social · 03/05/2025
I am extremely pleased to share this feature articulating why I have lost my sanity lately. www.science.org/content/arti...
science.org
U.S. scientists’ lives and careers are being upended. Here are five of their stories
As the second Trump administration sends U.S. science into upheaval, countless researchers are fighting for their futures
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Marius Pachitariu @marius10p.bsky.social · 03/05/2025
🚀🔬🦠 Releasing 🤖Cellpose-SAM🤖, a cellular segmentation algorithm with superhuman generalization 🦸‍♀️. Try it now on 🤗 huggingface.co/spaces/mouse... paper: www.biorxiv.org/content/10.1... w/ @computingnature.bsky.social 1/n
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Gretchen Goldman, PhD @gretchentg.bsky.social · 02/05/2025
The scientific community is at a pivotal moment right now. And we are seeing things start to shift. Now is the time for scientists and scientific institutions to step up. No one is coming to save us. 🧵
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