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John Delaney

@johndelaney.bsky.social
231 followers 59 following 33 posts

Interested in .... molecular modeling, computational chemistry, QSAR, chemoinformatics doi.org/10.1016/j.drudis.2008.10.007

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Reposted by John Delaney
Dan Neidle @danneidle.bsky.social · 08/10/2026
Kemi Badenoch wants to exempt the family home from inheritance tax. But that creates a perverse incentive for elderly people to *upsize* to save IHT. That could double the cost of the policy, and push £100bn+ from savings into housing. A 🧵 on bad tax cuts.
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Tim Bale @timbale.bsky.social · 03/10/2026
Nice to have a letter in @economist.com - this one on why naughty Nigel's £72 million bung won't necessarily buy him the next election. #HowToSpendIt
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Ed Zitron @edzitron.com · 01/10/2026
Going to be honest this might be my favourite headline of the AI bubble
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Dan Neidle @danneidle.bsky.social · 01/10/2026
Manchester City cheated Premier League rules, the Commission found. Did it also cheat HMRC? We've examined the decision and leaked Mancini documents. We think City likely failed to pay £12m in tax. There should be a criminal investigation. Thread:
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Rich @pibasedlifeform.bsky.social · 29/09/2026
Viz letter page will always say it best thou
The famous Viz letters about Lance Armstrong on drugs
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EMBL-EBI @ebi.embl.org · 28/09/2026
We often get asked what biocurators do so we quizzed our colleague Emily Bowler-Barnett about her role in the UniProt team. We also explored why biocuration is critical to open science, how AI is changing the field & how Emily's dog got her name 🐕
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Ben Ansell @benansell.bsky.social · 28/09/2026
Good thing that this couldn’t have been predicted almost a year ago <runs bitter victory lap> and the government didn’t just blithely carry on doing the same thing. www.prospectmagazine.co.uk/politics/718...
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Mark Appleby @markappleby.bsky.social · 26/09/2026
The false ”rogue” narrative rolls out again. These autonomous hacking tools have been built and released on the orders of tech bro execs who need to be prosecuted each time this happens. www.nytimes.com/2026/09/25/t...
nytimes.com
OpenAI’s A.I. Went Rogue and Meddled With U.S. Government Websites
The company did not learn until recently that its technology had meddled with websites for the Education and Commerce Departments and the Securities and Exchange Commission.
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Daniel Knowles @dlknowles.bsky.social · 26/09/2026
Some unintended consequences I suspect the rise of AI agents will create: 1. Restaurants that only take reservations by hand written letter, or more likely, don't take them at all. 2. Gigs where you can only buy tickets in person. 3. Businesses that operate without websites.
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James O’Brien @mrjamesob.bsky.social · 24/09/2026
A characteristically coruscating thread from Mr Snow.
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John Harris @johnharris1969.bsky.social · 24/09/2026
Also upcoming in budget Tax breaks on stag weekends in Prague Legalization of cocaine but only if it's crap, cut and suspiciously cheap Limited edition pound coin featuring Finchy from The Office
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Mark Thompson @markreckons.bsky.social · 24/09/2026
Just seen Danny Tommo referred to as "Captain Thugwash" and seriously, that's excellent work.
static.klipy.com
Amy Poehler's Perfect Chef's Kiss
ALT: Amy Poehler's Perfect Chef's Kiss
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Sarah O'Connor @sarahoconnorft.ft.com · 24/09/2026
Please excuse me while I scream into a cushion at the thought of ALL the articles I had to write on the "UK productivity puzzle" in the 2010s www.ft.com/content/c819...
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General Boles @generalboles.bsky.social · 24/09/2026
"do you have any cleaning experience?" "well we've scrubbed away every trace of our involvement in the last government"
Conservative leader Kemi Badenoch and Shadow Work and Pensions Secretary Helen Whately visit Cleanology on September 24, 2026 in London, England. 

They are carrying cleaning equipment including a blue Charles hoover
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Andre the Chemist @andrechemist.bsky.social · 21/09/2026
It's a shame no chemist ever came up with the idea to say "I'm working on something that might kill all of humanity, so please give me several billion dollars so I can stop myself" That feels like something that should've been right up our alley
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Katie Martin @katie0martin.ft.com · 13/09/2026
Good job the entire stock market is not perched on AI now the teenage boys running it have decided it's a massive nuclear bomb and they don't know how to turn it off *Taps ear piece*
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Peter Geoghegan @petergeoghegan.bsky.social · 19/09/2026
🔴 Something Tom Watson won't tell you: Five police forces in the East Midlands working with Palantir on a controversial surveillance programme are ending their involvement Exclusive by Democracy for Sale and Liberty Investigates. democracyforsale.substack.com/p/revealed-f...
democracyforsale.substack.com
Revealed: Five police forces to drop Palantir surveillance tool
Exclusive: Palantir's UK policing ambitions take a hit as East Midlands forces end their involvement in a controversial data pilot.
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Jim Pickard @pickardje.bsky.social · 18/09/2026
my brilliant colleague @robertshrimsley.bsky.social on the threat from Elon Musk’s X platform www.ft.com/content/f270...
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Tim Bale @timbale.bsky.social · 19/09/2026
That wouldn't happen to be tax paid on profits made, in no small part, from the delusions and often outright misery of thousands upon thousands of his fellow countrymen, would it?
ft.com
UK’s top taxpayer says he would ‘not wish to be reborn’ in Britain
Betfred founder Fred Done threatens 500 shop closures over tax rises that have left him fearful for the UK’s prospects
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Derek Lowe @dereklowe.bsky.social · 17/09/2026
How far can AI get you in designing and optimizing new antibodies? Not as far as you might have thought:
science.org
The State of AI Antibody Design
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The Onion @theonion.com · 16/09/2026
Gas Station Price Sign Using Scientific Notation
Gas Station Price Sign Using Scientific Notation
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Heather Burns @heatherburnstech.bsky.social · 16/09/2026
Regular reminder that JG Ballard’s final novel, “Kingdom Come” (2006), is about a far-right English town which creates their own militarised breakaway state in a shopping mall, where they worship the gods of St George and consumerism. Old JG wrote it as tongue-in-cheek satire. At the time.
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By Cory Doctorow (GPG 0xBF3D9110957E5F4C) @doctorow.pluralistic.net · 12/09/2026
If you showed up at Defcon and gave talk about how your autonomous malware did something unexpected and damaged someone else's computers, the first question from the audience would be "Why are you so shit at making secure sandboxes?" It wouldn't be "How are you so awesome at making hacking tools?"
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Tim Bale @timbale.bsky.social · 11/09/2026
Oh, and if you're ever in Eastbourne and you need gift shop!
RNLI museum, Eastbourne.
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PoliticsHome @politicshome.bsky.social · 11/09/2026
The cost of concealment: why polling needs transparency ✍️ Alastair McCapra www.politicshome.com/opinion/articl…
politicshome.com
The cost of concealment: why polling needs transparency
Public opinion is one of the great shaping forces in British political life, and polling is how we listen to it.
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Will Jennings📉🗳️ @drjennings.bsky.social · 09/09/2026
Surprising this story isn't getting more coverage...
portsmouth.co.uk
Protestors confuse Pakistan cricket team for migrants after gathering at hotel
Misinformation caused groups of people to gather at The Marriott Hotel
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Owen Boswarva @owenboswarva.bsky.social · 08/09/2026
This is that "vendor lock-in" problem you may have heard about Recent report from the SITC Committee committees.parliament.uk/committee/13... Particularly egregious because it's Palantir, obv #techpolicy #publicprocurement
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Tim Bale @timbale.bsky.social · 08/09/2026
'[Labour] has failed to act seriously to tackle the problem, whether through persuasion or the force of law. Instead, it has now produced two governments whose response to acts of thuggery and intimidation is to reiterate that perhaps the thugs have a point.' @stephenkb.bsky.social 👏 (but also 🤬)
ft.com
Labour’s muddled migration policy won’t stop thuggery
A government that can’t distinguish between ‘legitimate concerns’ and open racism is only making things worse
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Tim Bale @timbale.bsky.social · 08/09/2026
On days like this, thank heavens for not-so-small mercies!
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Tim Bale @timbale.bsky.social · 07/09/2026
😆👏
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Old British Telly @oldbritishtelly.co.uk · 07/09/2026
[1965] Tomorrow's World - Pioneering sound engineer Delia Derbyshire, who realised Ron Grainer's Doctor Who Theme, shows how electronic sounds are produced and demonstrates the techniques used to build them into scores for the likes of Quatermass and the Pit.
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Otto English @ottoenglish.bsky.social · 05/09/2026
All those British politicians like Badenoch and Farage who were such huge fans of Trump and Javier Milei should be asked repeatedly to state where they stand now... and what's changed
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David Henig @davidheniguk.bsky.social · 03/09/2026
Afraid I profoundly disagree with this paper, the theory of performance management when turned into reality becomes one of the most divisive morale-ruining events in the calendar, an opportunity to let bullying run amok particularly with the fallacies of distribution curves.
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Abby Innes @abbyinnes.bsky.social · 31/08/2026
No, and for same ontological and epistemological reasons Soviet socialism failed, because we are not God, we cannot read the future in our real, evolving, open-system world full of imaginative people… in short: because we do not live in a computable world…🤔 www.ft.com/content/cd3f...
ft.com
Could AI revive the socialist dream?
Artificial intelligence has the potential to both reignite and overturn the century-old debate over central economic planning
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John Bull @garius.bsky.social · 27/08/2026
Many years ago, I wrote down this bit of a speech Obama gave to an audience in Silicon Valley. Because it absolutely NAILED the difference between government and business.
The final thing I’ll say is that government will never run the way Silicon Valley runs because, by definition, democracy is messy. This is a big, diverse country with a lot of interests and a lot of disparate points of view. And part of government’s job, by the way, is dealing with problems that nobody else wants to deal with.

So sometimes I talk to CEOs, they come in and they start telling me about leadership, and here’s how we do things. And I say, well, if all I was doing was making a widget or producing an app, and I didn’t have to worry about whether poor people could afford the widget, or I didn’t have to worry about whether the app had some unintended consequences then I think those suggestions are terrific.

That's not, by the way, to say that there aren't huge efficiencies and improvements that have to be made.

But the reason I say this is sometimes we get, I think, in the scientific community, the tech community, the entrepreneurial community, the sense of we just have to blow up the system, or create this parallel society and culture because government is inherently wrecked.

No, it's not inherently wrecked; it's just government has to care for, for example, veterans who come home. That's not on your balance sheet, that's on our collective balance sheet, because we have a sacred duty to take care of those veterans. And that's hard and it's messy, and we're building up legacy systems that we can't just blow up.
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Republicans Against Trumpism @rpsagainsttrump.bsky.social · 28/08/2026
WTF
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EMBL-EBI @ebi.embl.org · 27/08/2026
Read more about Dame Janet Thornton’s illustrious career: www.ebi.ac.uk/about/news/a...
ebi.ac.uk
Janet Thornton retires: a pioneer in structural bioinformatics
In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments shaping the field of bioinformatics.
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Brilliant Maps @brilliantmaps.bsky.social · 22/08/2026
The two types of people in this world Explanation: brilliantmaps.com/uk-plugs/
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John Bull @garius.bsky.social · 19/08/2026
Back when i was editor of @lonrec.bsky.social the BBC asked me during an interview if i thought the Elizabeth line would be Sadiq Khan's big legacy for London. i said: "no. it's ULEZ expansion." they looked at me like i had three heads. Every year though there's more and more proof I was right.
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Dmitry Grozoubinski @explaintrade.com · 15/08/2026
It's me, a Telegraph columnist, taking a break screaming bloody murder about fairness in the women's sports I wouldn't be caught dead watching to wax lyrical about academic integrity in sociology, a field I consider to be fake, at institutions I consider to be communist indoctrination centers.
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Declan Gaffney @greyskiesthinking.bsky.social · 13/08/2026
OMG actual Blackshorts!
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Philip Ball @philipcball.bsky.social · 12/08/2026
In my column for @thenewworldmag.bsky.social this week, I look at the shitshow that is the "trial" of Anthony Fauci, and say that it needs to draw condemnation from the scientific community in the strongest terms. It's Stalinist stuff. www.thenewworld.co.uk/philip-ball-...
thenewworld.co.uk
The grotesque show trial of Anthony Fauci
The White House’s chief medical adviser was not perfect during Covid, but science must resist his persecution by conspiracy-deranged Republicans
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Saloni @scientificdiscovery.dev · 11/08/2026
BIG NEW piece by me. A few years ago, if you asked me to summarize my entire worldview in one article, I would’ve said it was too broad and too difficult. But this year, I decided to do it.
worksinprogress.co
Every disease is a policy failure
Few people know how much medicine has progressed in their lifetimes. Fewer know how much faster it could be progressing.
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Andrew R @excelpope.net · 12/08/2026
Can't believe that Europe is getting the same eclipse as us. Was Brexit for nothing?
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Grumio @grumio.eurosky.social · 10/08/2026
There’s a certain irony in the owner of the Big Baps lay-by cafe complaining about doggers www.examinerlive.co.uk/news/west-yo...
examinerlive.co.uk
Police to investigate Brighouse 'dogging hotspot' behind Big Baps cafe
Organisations set to work together to 'address concerns' raised about the Brighouse 'dogging site'
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David Quantick @quantick.bsky.social · 10/08/2026
"The objection appeared on page 75 of a press release in a section with a non-functioning hyperlink that takes the user back to the page they were on before."
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Richard Smyth @rsmythfreelance.bsky.social · 04/08/2026
Bede's World! Bede's World! Party time! Venerable!
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Charlie Stross @cstross.bsky.social · 05/08/2026
My answer is LOL ROFL (dickbrain) The terminally AI-pilled can't even *imagine* some people have *never* asked stochastic parrots to cheat at their job for them.
Screencap of a social media post by: kavishj611 
 
 All the people who are anti-Al or want to
 slow Al progress, I have one question:
 If Al disappeared tomorrow, could you
 still get through an entire workday
 without ChatGPT, Claude, or any other
 Al tool?
 
Imagine Al was suddenly banned.
 Would you actually be willing to give it
 up?
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James Chalmers @jameschalmers.bsky.social · 04/08/2026
Yes I acknowledge it makes sense in context but “I need my car to meet criminals” is now my favourite basis for an attempted exceptional hardship plea. www.bbc.co.uk/news/article...
Best-selling crime author Lynda La Plante has been disqualified from driving for six months, despite tearfully telling the court a ban would end her writing career.
The 83-year-old author and screenwriter told Lavender Hill Magistrates' Court she needed her car to meet criminals and sources for research into her next works of fiction.
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