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Jesse Brown

@jesseab.bsky.social
343 followers 83 following 50 posts

Neuro + data scientist, building radiata.ai - better brain biomarkers.

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Reposted by Jesse Brown
Aperture Neuro @apertureohbm.bsky.social · 13/05/2026
Do longer scans really improve prediction and reduce costs in BWAS? Explore the commentary series: • Breakspear: doi.org/10.52294/001... • Bijsterbosch: doi.org/10.52294/001... • McIntosh: doi.org/10.52294/001... @drbreaky.bsky.social @janinebijsterbosch.bsky.social @ar0mcintosh.bsky.social
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Gagan Wig @gaganwig.bsky.social · 31/03/2026
Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely New @pnas.org paper🧵 www.pnas.org/doi/10.1073/...
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Arne Ekstrom @adekstreme.bsky.social · 19/03/2026
We are hiring a postdoctoral fellow as part of a recently funded R01 on memory and dementia. Please circulate widely: arizona.csod.com/ux/ats/caree...
arizona.csod.com
Postdoctoral Research Associate I (Psychology)
Duties and Responsibilities: Lead the MRI component of the project, including neuroimaging data collection, preprocessing, and analysis.Integrate...
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The Transmitter @thetransmitter.bsky.social · 17/03/2026
A new data-sharing policy proposed by the NIH would result in “substantial harm to scientific progress,” a neuroimaging consortium says. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/data-sharing...
thetransmitter.org
Neuroscientists challenge NIH’s proposed data-access policy
The changes would restrict the sharing of human neuroimaging, transcriptomic and genetic data.
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Reposted by Jesse Brown
The Transmitter @thetransmitter.bsky.social · 21/01/2026
When a brain researcher solved a logistical problem by going rogue, the idea proved remarkably infectious. By @lyrebard.bsky.social #neuroskyence www.thetransmitter.org/brain-imagin...
thetransmitter.org
A brief history of precision self-scanning
When a researcher solved a logistical problem by going rogue, the idea proved remarkably infectious.
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Jesse Brown @jesseab.bsky.social · 17/01/2026
Been pondering the lesion network mapping study all day. Here's my $0.02 [🧵]:
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Reposted by Jesse Brown
The Transmitter @thetransmitter.bsky.social · 16/01/2026
More than 200 published studies and at least seven ongoing clinical trials rely on potentially faulty brain network maps, according to a study published yesterday. By @avaskham.bsky.social #neuroskyence www.thetransmitter.org/brain-imagin...
thetransmitter.org
Methodological flaw may upend network mapping tool
The lesion network mapping method, used to identify disease-specific brain networks for clinical stimulation, produces a nearly identical network map for any given condition, according to a new study.
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Reposted by Jesse Brown
Max Elliott @maxwellelliott.bsky.social · 09/01/2026
I am recruiting a Postdoc to join my lab at UMN. If you or someone you know is interested in studying individual differences in brain and cognitive aging, check out the listing and my website in my bio and apply! I appreciate RTs to help get the word out as well :)
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Jesse Brown @jesseab.bsky.social · 24/12/2025
Paradigm shift away from regionalization, finally?
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Jesse Brown @jesseab.bsky.social · 25/11/2025
Excited to share our new work in @natcomms.nature.com: Functional network collapse in neurodegenerative disease How does functional connectivity change across dementia types and stages? www.nature.com/articles/s41...
nature.com
Functional network collapse in neurodegenerative disease - Nature Communications
This study demonstrates that brain functional network imbalance appears linked to progressive brain atrophy and cognitive decline across the dementia spectrum.
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tor @torwager.bsky.social · 14/11/2025
❤️ Bluesky fMRI people! 3-day #fMRI course live online Jan 7-9, 2026. #SPM, #ICA, GLM, connectivity, mediation, MRI physics, #DataScience with @vcalhoun.bsky.social and Kent Kiehl. We love talking methods & connecting with colleagues! Come join us! Register here: sites.google.com/dartmouth.ed...
sites.google.com
fMRI Course
Instructors
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Reposted by Jesse Brown
Randy McIntosh @ar0mcintosh.bsky.social · 21/10/2025
A couple of computational neuroscience positions at UT Dallas. This is an emerging program with great collaboration potential. jobs.utdallas.edu/postings/30394
jobs.utdallas.edu
Open Rank faculty positions in Computational Neuroscience
Position Description The Department of Neuroscience at The University of Texas at Dallas seeks to hire up to two tenure-system faculty members (open rank) with expertise in neural coding, neural compu...
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Reposted by Jesse Brown
Caterina Gratton @caterinagratton.bsky.social · 16/10/2025
Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization? @rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print): go.illinois.edu/Gratton2025-... #neuroskyence #psychscisky #MedSky 🧵👇
go.illinois.edu
Dense Phenotyping of Human Brain Network Organization Using Precision fMRI
The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...
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Bratislav Misic @misicbata.bsky.social · 16/09/2025
Network spreading and local biological vulnerability in amyotrophic lateral sclerosis | doi.org/10.1038/s420... How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
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Jesse Brown @jesseab.bsky.social · 15/09/2025
Stimulating the LGN with ultrasound and real-time fMRI, this is cool. Ultrasound system for precise neuromodulation of human deep brain circuits. www.nature.com/articles/s41...
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Reposted by Jesse Brown
Brad Postle @bradpostle.bsky.social · 09/09/2025
The Dept. of Psychology at the U. Wisconsin–Madison has an opening for an Assistant Professor in the area of Computational Neuroscience and/or Cognitive Science, with an emphasis on artificial intelligence (AI). Domain of behavior or cognition is open. Details at jobs.wisc.edu/jobs/assista...
jobs.wisc.edu
Assistant Professor of Psychology - Madison, Wisconsin, United States
Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:FacultyEmployment Type:Regula...
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Jesse Brown @jesseab.bsky.social · 08/09/2025
Would be perfectly happy if cool new mechanistic brain function studies like this one omitted the individual trait prediction. Don't think every new finding needs a cognitive correlation to have merit. www.nature.com/articles/s41...
nature.com
Large-scale cortical functional networks are organized in structured cycles - Nature Neuroscience
The human brain cycles through a repertoire of brain networks on a 1-second timescale during rest and tasks. This cycling appears to allow periodic engagement of essential cognitive functions, with th...
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Reposted by Jesse Brown
Ben Hayden @benhayden.bsky.social · 04/09/2025
Sad day for peope who still believe brain areas are the primary organizational units of function in the brain. www.nature.com/articles/s41...
nature.com
A brain-wide map of neural activity during complex behaviour - Nature
The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...
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Jesse Brown @jesseab.bsky.social · 13/08/2025
Doing a deep dive on TMS. Kinda crazy how much of this field is built on DLPFC-sgACC anticorrelation. One little edge.
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Lucina Uddin @lucinauddin.bsky.social · 28/05/2025
When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...
nature.com
The history and future of resting-state functional magnetic resonance imaging - Nature
This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...
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Eric Topol @erictopol.bsky.social · 08/05/2025
Using the advances in the science of aging to prevent the major age-related diseases (no reversal of aging required) www.theguardian.com/world/2025/m... @theguardian.com
theguardian.com
‘Get rid of the pseudoscience’: top doctor’s plan to improve America’s health
Eric Topol says we can prevent age-related disease and live fuller lives – but only if we reject anti-science ‘malarkey’
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Jean-Rémi King @jeanremiking.bsky.social · 01/05/2025
🔴 Our `Brain and AI` team at Meta has a new Research Engineer position in Paris to work on infrastructure and scale deep learning experimentations: www.metacareers.com/jobs/1769841... We'll favor industry experience or Github track record.
metacareers.com
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The Transmitter @thetransmitter.bsky.social · 16/04/2025
The scientific community needs to develop processes to support, hire and retain researchers whose work sits between traditional fields of study, writes @avramholmes.bsky.social #neuroskyence www.thetransmitter.org/future-of-fm...
thetransmitter.org
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
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Reposted by Jesse Brown
Eric Topol @erictopol.bsky.social · 14/04/2025
Most people haven’t heard of this test, which is available in the US. It accurately predicts Alzheimer’s (not just if there’s a risk, but when). It is modulated by exercise and likely other lifestyle factors. Here’s (almost) everything we know about it erictopol.substack.com/p/the-breakt...
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Sam Krimmel @samkrimmelneuro.bsky.social · 10/04/2025
It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in @naturecomms.bsky.social we show that current thinking on the red nucleus is in need of a serious upgrade. rdcu.be/ehbOy
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Lianglong Sun @longonga.bsky.social · 04/04/2025
Happy to share that our article “Human lifespan changes in the brain’s functional connectome” is now published online at Nature Neuroscience @natureneuro.bsky.social ! Many thanks to all collaborators & data contributors, and the editor team & reviewers! www.nature.com/articles/s41...
nature.com
Human lifespan changes in the brain’s functional connectome - Nature Neuroscience
Sun et al. report human lifespan changes in the brain’s functional connectome in 33,250 individuals, which highlights critical growth milestones and distinct maturation patterns and offers a normative...
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Reposted by Jesse Brown
Carolyn Fredericks @carolynfredericks.bsky.social · 28/03/2025
We are HIRING!! Postdoc for multimodal imaging lab at Yale. If you get excited about preclinical and prodromal states, atypical Alzheimer’s, graph theory, predictive modeling, and/or baked goods at lab meetings, come join us: postdocs.yale.edu/postdoctoral... Please share with your circles!
The Fredericks Lab! - with deliberately poor photoshopping of lab members who couldn't be there that day.
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Jesse Brown @jesseab.bsky.social · 31/03/2025
Proxies aren't the thing, the thing is the thing. Just don't forget what the "thing" is.
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Reposted by Jesse Brown
Frederic Schaper @fredschaper.bsky.social · 24/03/2025
Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:
nature.com
A generalized epilepsy network derived from brain abnormalities and deep brain stimulation - Nature Communications
Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce general...
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Jesse Brown @jesseab.bsky.social · 21/01/2025
Here's a new open dataset of ~4000 processed brain structural MRIs from across the lifespan: huggingface.co/datasets/rad... Get it in three lines of code: pip install datasets from datasets import load_dataset ds = load_dataset("radiata-ai/brain-structure", trust_remote_code=True)
huggingface.co
radiata-ai/brain-structure · Datasets at Hugging Face
We’re on a journey to advance and democratize artificial intelligence through open source and open science.
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Reposted by Jesse Brown
Kevin Mitchell @wiringthebrain.bsky.social · 18/01/2025
Rethinking Brain Mechanisms in the Light of Evolution with Paul Cisek youtu.be/CnT7jaQX4X8?... - if you want to understand what brains are for (and their functional organisation), this is the way... 👍👏
youtu.be
Rethinking Brain Mechanisms in the Light of Evolution with Paul Cisek
YouTube video by Kempner Institute at Harvard University
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Reposted by Jesse Brown
Nature Neuroscience @natneuro.nature.com · 17/01/2025
Using a brain–computer interface to challenge monkeys to override their natural time courses of neural activity reveals that the time courses are highly robust, suggestive of network-level computational mechanisms @aaronbatista.bsky.social and colleagues www.nature.com/articles/s41...
nature.com
Dynamical constraints on neural population activity - Nature Neuroscience
Oby, Degenhart, Grigsby and colleagues used a brain–computer interface to challenge monkeys to override their natural time courses of neural activity. They found the time courses to be highly robust, ...
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Jesse Brown @jesseab.bsky.social · 07/01/2025
Here's how you can build classifiers for brain structural MRI data on radiata.ai. www.youtube.com/watch?v=oDan... We built this to make it easier to: - set up and run machine learning models on the fly with no installs
youtube.com
Radiata Brain Imaging Classification
YouTube video by Radiata
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Jesse Brown @jesseab.bsky.social · 01/12/2024
Pretty amazing that we can now do regression with words and concepts (via LLM embeddings) as predictors. arxiv.org/abs/2411.14708
arxiv.org
Understanding LLM Embeddings for Regression
With the rise of large language models (LLMs) for flexibly processing information as strings, a natural application is regression, specifically by preprocessing string representations into LLM embeddi...
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Jesse Brown @jesseab.bsky.social · 18/11/2024
Our brain biomarker engine is live at radiata.ai. Here's how you can use our interactive latent space to explore brain anatomy individual differences in structural MRI scans. www.youtube.com/watch?v=EaJy...
youtube.com
Radiata Brain Latent Space
YouTube video by Radiata
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Jesse Brown @jesseab.bsky.social · 27/02/2024
Enjoying this, giving me 1996 feels and hope for the next wave.
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Jesse Brown @jesseab.bsky.social · 26/11/2023
Optimal approaches to analyzing functional MRI data in glioma patients www.sciencedirect.com/science/arti...
sciencedirect.com
Optimal approaches to analyzing functional MRI data in glioma patients
Resting-state fMRI is increasingly used to study the effects of gliomas on the functional organization of the brain. A variety of preprocessing techni…
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